Concomitant overdosing of other drugs in patients with paracetamol poisoning

British Journal of Clinical Pharmacology

Volumn 53, Issue 5, 2002, Pages 535-541

  Schmidt, Lars E ^a   Dalhoff, Kim ^a  

^a Rigshospitalet   (Denmark)

Author keywords

Acetaminophen; Acetylsalicylic acid; Benzodiazepines; Cointoxication; Drug interaction; Liver failure; NSAID; Opioid analgesics; Paracetamol; Poisoning

Indexed keywords

ACETYLCYSTEINE; ACETYLSALICYLIC ACID; ANALGESIC AGENT; BENZODIAZEPINE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL;

ADOLESCENT; ADULT; AGED; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG INTOXICATION; DRUG OVERDOSE; FEMALE; HEPATIC ENCEPHALOPATHY; HOSPITAL ADMISSION; HUMAN; KIDNEY DISEASE; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; TREATMENT OUTCOME; CHEMICALLY INDUCED DISORDER; CHILD; DENMARK; DRUG INTERACTION; INTOXICATION; LIVER DISEASE; MIDDLE AGED; MORTALITY;

ACETAMINOPHEN; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, NON-NARCOTIC; CHILD; DENMARK; DRUG INTERACTIONS; FEMALE; HUMAN; KIDNEY DISEASES; LIVER DISEASES; MALE; MIDDLE AGE; OVERDOSE; HUMANS; MIDDLE AGED;

EID: 0035999646     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2002.01564.x     Document Type: Article

References (47)

1. Danske analgetikaforgiftninger i en 14 års periode - En registerundersøgelse for 1979-92
2. Drugs taken in fatal and non-fatal self-poisoning: A study in South London
3. 1993 Annual report of the American Association of Poison Control Centers toxic exposure surveillance system
4. A 7-year experience of severe acetaminophen-induced hepatotoxicity
5. Etiology and outcome for 295 patients with acute liver failure in the United States
6. Risk factors in the development of adverse reactions to N-acetylcysteine in patients with paracetamol poisoning
7. Paracetamol overdose - Facts not misconceptions
8. Combined aspirin/acetaminophen intoxication
9. The effect on paracetamol absorption of stimulation and blockade of β-adrenoceptors
10. Effect on premedication on drug absorption and gastric emptying
11. Effect of i.v. metoclopramide on gastric emptying after opioid premedication
12. Effect of acetylsalicylic acid on a toxic dose of acetaminophen in the mouse
13. The effect of diazepam in the recovery of rabbits from acute acetaminophen poisoning
14. Paracetamol overdose. Protective effect of concomitantly ingested antimuscarinic drugs and codeine
15. Cimetidine as adjunctive treatment for acetaminophen overdose
16. Disulfiram prevents acetaminophen hepatotoxicity in rats
17. Does hypothermia protect against the development of hepatitis in paracetamol overdose?
18. 2 inhibitors
19. Effects of calcium channel blocking agents on calcium and centrilobular necrosis in the liver of rats treated with hepatotoxic agents
20. Acetaminophen hepatotoxicity: Is there a role for prostaglandin synthesis?
21. Cytoprotection by iloprost against paracetamol-induced toxicity in hamster isolated hepatocytes
22. Effect of oral contraceptive steroids on acetaminophen metabolism and elimination
23. Depression of hepatic glutathione by opioid analgesic drugs in mice
24. Factors influencing paracetamol metabolism
25. Single dose oxazepam has no effect on acetaminophen clearance or metabolism
26. Effect of diazepam on drug absorption and gastric emptying in man
27. Influence of sex and oral contraceptive steroids on paracetamol metabolism
28. Therapeutic doses of codeine have no effect of acetaminophen clearance or metabolism
29. Long-term anticonvulsant therapy worsens outcome in paracetamol-induced fulminant hepatic failure
30. Rekommandation for behandling af paracetamolforgiftning
31. Early indicators of prognosis in fulminant hepatic failure
32. The effect of access to lethal methods of injury on suicide rates
33. Does the availability of prescribed drugs affect rates of self poisoning?
34. Ethical issues in European psychiatry
35. A comparison of drugs taken in fatal and non-fatal deliberate self-poisoning
36. Benzodiazepine poisoning. Experience of 702 admissions to an intensive care unit during a 14-year period
37. Brain edema and portal-systemic encephalopathy
38. Plasma and CSF benzodiazepine receptor ligand concentrations in cirrhotic patients with hepatic encephalopathy: Relationship to severity of encephalopathy and to pharmaceutical benzodiazepine intake
39. Imidazole and indomethacin improve hepatic perfusion in sepsis
40. Effects of ibuprofen and indomethacin on the regional circulation in newborn piglets
41. Indomethacin normalizes intracranial pressure in acute liver failure: A twenty-three-year-old woman treated with indomethacin
42. Indomethacin for brain edema following stroke
43. Indomethacin. A review of its cerebral blood flow effects and potential use for controlling intracranial pressure in traumatic brain injury patients
44. Acute salicylate self-poisoning in 177 consecutive patients treated in ICU
45. Adult salicylate poisoning, deaths and outcome in patients with high plasma salicylate concentrations