3-Hydroxy-3-methylglutaryl coenzyme A reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture

Circulation Research

Volumn 83, Issue 5, 1998, Pages 490-500

  Guijarro, Carlos ^a,d   Blanco Colio, Luis Miguel ^a   Ortego, Mónica ^a   Alonso, Covadonga ^b   Ortiz, Alberto ^a   Plaza, Juan José ^a   Díaz, Cristina ^c   Hernández, Gonzalo ^c   Egido, Jesús ^a,e  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b INIA   (Spain)

^c Parke Davis SA   (Spain)

^d HOSPITAL UNIVERSITARIO FUNDACIÓN ALCORCÓN   (Spain)

^e Vascular Research Laboratory   (Spain)

Author keywords

Apoptosis; Atherosclerosis; Mevalonate; Protein isoprenylation; Rho; Smooth muscle cell

Indexed keywords

ADENOSINE; ANTILIPEMIC AGENT; ATORVASTATIN; DIMETHYLALLYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOCORTIN 5; MEVALONIC ACID; MEVINOLIN; PRAVASTATIN; SIMVASTATIN; SQUALENE; UBIQUINONE;

ANIMAL CELL; APOPTOSIS; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0032494101     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.83.5.490     Document Type: Article

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