Role of PDE3A in regulation of cell cycle progression in mouse vascular smooth muscle cells and oocytes: Implications in cardiovascular diseases and infertility

Current Opinion in Pharmacology

Volumn 11, Issue 6, 2011, Pages 725-729

  Begum, Najma ^a   Shen, Weixing ^a   Manganiello, Vincent ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 25B; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHODIESTERASE 3A; PHOSPHODIESTERASE 3B; PHOSPHODIESTERASE III; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; GROWTH REGULATION; HEART MUSCLE CONTRACTILITY; INFERTILITY; KNOCKOUT MOUSE; MEIOSIS; NONHUMAN; OOCYTE; OOCYTE MATURATION; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; RESTENOSIS; VASCULAR SMOOTH MUSCLE;

EID: 82255175547     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2011.10.006     Document Type: Review

References (44)

1. T.M. Lincoln, X. Wu, H. Sellak, N. Dey, and C.S. Choi Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase Front Biosci 11 2006 356 367 (Pubitemid 43253498)
2. N. Begum Insulin signaling in the vasculature Front Biosci 8 2003 796 804
3. M. Conti, C.B. Andersen, F. Richard, C. Mehats, S.Y. Chun, K. Horner, C. Jin, and A. Tsafriri Role of cyclic nucleotide signaling in oocyte maturation Mol Cell Endocrinol 187 2002 153 159 (Pubitemid 34436944)
4. S. Vaccari, J.L. Weeks, M. Hsieh, F.S. Menniti, and M. Conti cGMP signaling is involved in the lutenizing hormone-dependent meiotic maturation of mouse oocytes Biol Reprod 8 2009 595 604
5. S. Vaccari, K. Horner, L.M. Mehlmann, and M. Conti Generation of mouse oocytes defective in cAMP synthesis and degradation: endogenous cAMP is essential for meiotic arrest Dev Biol 316 2008 124 134
6. R. Ross The pathogenesis of atherosclerosis: a perspective for the 1990s Nature 362 1993 801 809 (Pubitemid 23132154)
7. S.H. Francis, J.L. Busch, J.D. Corbin, and D. Sibley cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action Pharmacol Rev 62 2010 525 563
8. D.H. Maurice, D. Palmer, D.G. Tilley, H.A. Dunkerley, S.J. Netherton, D.R. Raymond, H.S. Elbatarny, and S.L. Jimmo Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system Mol Pharmacol 64 2003 533 546 (Pubitemid 37048555)
9. T. Aizawa, H. Wei, J.M. Miano, J. Abe, B.C. Berk, and C. Yan Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells Circ Res 93 2003 406 413 (Pubitemid 37100005)
10. D.A. Kass, E. Takimoto, T. Nagayama, and H.C. Champion Phosphodiesterase regulation of nitric oxide signaling Cardiovasc Res 75 2007 303 314 (Pubitemid 46961917)
11. S. Chan, and C. Yan PDE1 isozymes, key regulators of pathological vascular remodelling Curr Opin Pharmacol 11 2011 715 719
12. M. Movsesian, O. Wever-Pinzon, and F. Vandeput PDE3 inhibition in dilated cardiomyopathy Curr Opin Pharmacol 11 2011 702 708
13. C. Lugnier PDE inhibitors: a new approach to treat metabolic syndrome? Curr Opin Pharmacol 11 2011 693 701
14. S. Beca, R. Aschars-Sobbi, B.K. Panama, and P.H. Backx Regulation of murine cardiac function by phosphodiesterases type 3 and 4 Curr Opin Pharmacol 11 2011 709 714
15. M. Conti Phosphodiesterases and regulation of female reproductive function Curr Opin Pharmacol 11 2011 660 664
16. N. Begum, S. Hockman, and V. Manganiello PDE3A deletion suppresses proliferation of cultured murine VSMCs via inhibition of mitogen activated protein kinase signaling and alterations in critical cell cycle regulatory proteins J Biol Chem 286 2011 26238 26249
17. P.R. Nelson, S. Yamamura, L. Mureebe, H. Itoh, and K.C. Kent Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase J Vasc Surg 27 1998 117 125 (Pubitemid 28081167)
18. E.R. Isenovic, M.H. Kedees, S. Tepavcević, T. Milosavljević , G. Korićanac, A. Trpković, and P. Marche Role of PI3K/AKT, cPLA2 and ERK1/2 signaling pathways in insulin regulation of vascular smooth muscle cells proliferation Cardiovasc Hematol Disord Drug Targets 9 2009 172 180
19. G. Pages, P. Lenormand, G. L'Allemain, J.C. Chambard, S. Meloche, and J. Pouysségur Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation PNAS 90 1993 8319 8323 (Pubitemid 23277659)
20. J. Wu, P. Dent, T. Jelinek, A. Wolfman, M.J. Weber, and T.W. Sturgill Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate Science 262 1993 1065 1069 (Pubitemid 24035048)
21. H. Sun, N.K. Tonks, and D. Bar-Sagi Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1 Science 26 1994 3203 3213
22. R.C. Hewer, G.B. Sala-Newby, Y.J. Wu, A.C. Newby, and M. Bond PKA and Epac synergistically inhibit smooth muscle cell proliferation Mol Cell Cardiol 50 2011 87 98
23. Y.J. Wu, M. Bond, G.B. Sala-Newby, and A.C. Newby Altered S-phase kinase-associated protein-2 levels are a major mediator of cyclic nucleotide-induced inhibition of vascular smooth muscle cell proliferation Circ Res 98 2006 1141 1150 (Pubitemid 43948100)
24. B. Ducommun From growth to cell cycle control Semin Cell Biol 2 1991 233 324
25. T. Onishi The mitogenic effect of parathyroid hormone is associated with E2F-dependent activation of cyclin-dependent kinase 1 (cdc2) in osteoblast precursors J Bone Mineral Res 12 1997 1596 1605 (Pubitemid 27422360)
26. P. Brindle, P. Brindle, T. Nakajima, and M. Montminy Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP Proc Natl Acad Sci U S A 92 1995 10521 10525
27. O. Coqueret New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol 13 2003 65 722
28. C. Yan, C.L. Miller, and J. Abe Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart Circ Res 100 2007 489 501 (Pubitemid 46673258)
29. V. Adler, M.R. Pincus, T. Minamoto, S.Y. Fuchs, M.J. Bluth, P.W. Brandt-Rauf, F.K. Friedman, R.C. Robinson, J.M. Chen, and X.W. Wang Conformation-dependent phosphorylation of p53 Proc Natl Acad Sci U S A. 94 1997 1686 1691 (Pubitemid 27113896)
30. S.J. Netherton, and D.H. Maurice Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: Implications in angiogenesis Mol Pharmacol 67 2005 263 272 (Pubitemid 40069987)
31. Y. Inoue, K. Toga, T. Sudo, K. Tachibana, S. Tochizawa, Y. Kimura, Y. Yoshida, and H. Hidaka Suppression of arterial intimal hyperplasia by cilostamide, a cyclic nucleotide phosphodiesterase 3 inhibitor, in a rat balloon double-injury model Br J Pharmacol 130 2000 231 241 (Pubitemid 30261032)
32. C.C. Chini, J.P. Grande, E.N. Chini, and T.P. Dousa Compartmentalization of cAMP signaling in mesangial cells by phosphodiesterase isozymes PDE3 and PDE4. Regulation of superoxidation and mitogenesis J Biol Chem 272 1997 9854 9859 (Pubitemid 27171652)
33. R. Plevin, K. Malarkey, D. Aidulis, A. McLees, and G.W. Gould Cyclic AMP inhibitors inhibits PDGF-stimulated mitogen-activated protein kinase activity in rat aortic smooth muscle cells via inactivation of c-Raf-1 kinase and induction of MAP kinase phosphatase-1 Cell Signal 9 1997 323 328 (Pubitemid 27271653)
34. S. Fukumoto, H. Koyama, M. Hosoi, K. Yamakawa, S. Tanaka, H. Morii, and Y. Nishizawa Distinct role of cAMP and cGMP in the cell cycle control of vascular smooth muscle cells: cGMP delays cell cycle transition through suppression of cyclin D1 and cyclin-dependent kinase 4 activation Circ Res 85 1999 985 991
35. H. Koyama, K.E. Bornfeldt, S. Fukumoto, and Y. Nishizawa Molecular pathways of cyclic nucleotide-inhibition of arterial smooth muscle cell proliferation J Cell Physiol 186 2001 1 10
36. M.T. Osinski, B.H. Rauch, and K. Schrör Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A Mol Pharmacol 59 2001 1044 1050 (Pubitemid 32381583)
37. S. Hayashi, R. Morishita, H. Matsushita, H. Nakagami, Y. Taniyama, T. Nakamura, M. Aoki, K. Yamamoto, J. Higaki, and T. Ogihara Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21 Hypertension 35 2000 237 243 (Pubitemid 30054179)
38. R. Morishita A scientific rationale for the CREST trial results: evidence for the mechanism of action of cilostazol in restenosis Atherosclerosis Suppl 6 2005 41 66
39. M. Aoki, R. Morishita, S. Hayashi, N. Jo, K. Matsumoto, T. Nakamura, Y. Kaneda, and T. Ogihara Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model Diabetologia 44 2001 1034 1042 (Pubitemid 32778137)
40. B. Sun, H. Li, Y. Shakur, J. Hensley, S. Hockman, J. Kambayashi, V.C. Manganiello, and Y. Liu Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice Cell Signal 19 2007 1765 1771 (Pubitemid 46935432)
41. H. Zhao, Q. Guan, C.J. Smith, and J. Quilley Increased phosphodiesterase 3A/4B expression after angioplasty and the effect on VASP phosphorylation Eur J Pharmacol 590 2008 29 35
42. S. Masciarelli, K. Horner, C. Liu, S.H. Park, M. Hinckley, S. Hockman, T. Nedachi, C. Jin, M. Conti, and V. Manganiello Cyclic nucleotide phosphodiesterase 3A-KO mice as a model of female infertility J Clin Invest 114 2004 196 205 (Pubitemid 39071624)
43. W. Shen, F. Ahmad, S. Hockman, J. Ma, H. Omi, N. Raghavachari, and V. Manganiello Female infertility in PDE3A(-/-) mice: polo-like kinase 1 (Plk1) may be a target of protein kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A(-/-) mice Cell Cycle 9 2010 4720 4734
44. G. Pirino, M.P. Wescott, and P.J. Donovan Protein kinase A regulates resumption of meiosis by phosphorylation of Cdc25B in mammalian oocytes Cell Cycle 8 2009 665 670