Phosphodiesterases and regulation of female reproductive function

Current Opinion in Pharmacology

Volumn 11, Issue 6, 2011, Pages 665-669

  Conti, Marco ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC NUCLEOTIDE; GONADOTROPIN; N (3,5 DICHLORO 1 OXIDO 4 PYRIDINYL) 8 METHOXY 2 TRIFLUOROMETHYL 5 QUINOLINECARBOXAMIDE; PHOSPHODIESTERASE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IIIA; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; PHOSPHODIESTERASE V; PHOSPHODIESTERASE VIII; UNCLASSIFIED DRUG;

ARTICLE; BIRTH CONTROL; CELL CYCLE; DRUG MECHANISM; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; FEMALE GENITAL SYSTEM; HORMONE ACTION; KNOCKOUT MOUSE; NONHUMAN; OOCYTE; OOCYTE MATURATION; OVARY; OVARY FOLLICLE DEVELOPMENT; OVULATION; PRIORITY JOURNAL; REGULATORY MECHANISM; REPRODUCTION; SIGNAL TRANSDUCTION; SOMATIC CELL; TOXICITY TESTING;

EID: 82255162531     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2011.10.004     Document Type: Review

References (46)

1. A.M. Simon, D.A. Goodenough, E. Li, and D.L. Paul Female infertility in mice lacking connexin 37 Nature 385 1997 525 529 (Pubitemid 27074669)
2. R.L. Robker, D.L. Russell, S. Yoshioka, S.C. Sharma, J.P. Lydon, B.W. O'Malley, L.L. Espey, and J.S. Richards Ovulation: a multi-gene, multi-step process Steroids 65 2000 559 570
3. J.S. Richards, and S.A. Pangas New insights into ovarian function Handb Exp Pharmacol 198 2010 3 27
4. M. Conti, C.B. Andersen, F. Richard, C. Mehats, S.Y. Chun, K. Horner, C. Jin, and A. Tsafriri Role of cyclic nucleotide signaling in oocyte maturation Mol Cell Endocrinol 187 2002 153 159 (Pubitemid 34436944)
5. D.L. Segaloff, and M. Ascoli The lutropin/choriogonadotropin receptor - 4 years later Endocr Rev 14 1993 324 347
6. J.A. Dias, B.D. Cohen, B. Lindau-Shepard, C.A. Nechamen, A.J. Peterson, and A. Schmidt Molecular, structural, and cellular biology of follitropin and follitropin receptor Vitam Horm 64 2002 249 322 (Pubitemid 135763167)
7. J.S. Richards Perspective: the ovarian follicle - a perspective in 2001 Endocrinology 142 2001 2184 2193
8. M. Conti Specificity of the cyclic adenosine 3′,5′- monophosphate signal in granulosa cell function Biol Reprod 67 2002 1653 1661 (Pubitemid 35387993)
9. J.S. Richards, D.L. Russell, S. Ochsner, M. Hsieh, K.H. Doyle, A.E. Falender, Y.K. Lo, and S.C. Sharma Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization Recent Prog Horm Res 57 2002 195 220
10. R.L. Davis, and B. Dauwalder The Drosophila dunce locus: learning and memory genes in the fly Trends Genet 7 1991 224 229 (Pubitemid 121001927)
11. M. Conti, and J. Beavo Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling Annu Rev Biochem 76 2007 481 511
12. M. Conti, B.G. Kasson, and A.J. Hsueh Hormonal regulation of 3′,5′-adenosine monophosphate phosphodiesterases in cultured rat granulosa cells Endocrinology 114 1984 2361 2368 (Pubitemid 14120298)
13. J.Y. Park, F. Richard, S.Y. Chun, J.H. Park, E. Law, K. Horner, S.L. Jin, and M. Conti Phosphodiesterase regulation is critical for the differentiation and pattern of gene expression in granulosa cells of the ovarian follicle Mol Endocrinol 17 2003 1117 1130 (Pubitemid 36683719)
14. M. Sasseville, F.K. Albuz, N. Cote, C. Guillemette, R.B. Gilchrist, and F.J. Richard Characterization of novel phosphodiesterases in the bovine ovarian follicle Biol Reprod 81 2009 415 425
15. C. Chen, J. Wickenheisser, K.G. Ewens, W. Ankener, R.S. Legro, A. Dunaif, J.M. McAllister, R.S. Spielman, and J.F. Strauss III PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women Mol Hum Reprod 15 2009 459 469
16. S. Vaccari, J.L. Weeks II, M. Hsieh, F.S. Menniti, and M. Conti Cyclic GMP signaling is involved in the luteinizing hormone-dependent meiotic maturation of mouse oocytes Biol Reprod 81 2009 595 604
17. J. Schmidtke, H. Meyer, and J.T. Epplen Cyclic AMP phosphodiesterases of the rat ovary. Oestrous cycle dependent activity change of high affinity form Acta Endocrinol (Copenh) 95 1980 404 411 (Pubitemid 11211738)
18. L.C. Jin S, F. Richard, W.-P. Kuo, and A.J. D'Ercole Conti M: Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice Proc Natl Acad Sci U S A 96 1999 11998 112003
19. J.Y. Park, Y.Q. Su, M. Ariga, E. Law, S.L. Jin, and M. Conti EGF-like growth factors as mediators of LH action in the ovulatory follicle Science 303 2004 682 684 (Pubitemid 38141636)
20. S.D. McKenna, M. Pietropaolo, E.G. Tos, A. Clark, D. Fischer, D. Kagan, B. Bao, P.J. Chedrese, and S. Palmer Pharmacological inhibition of phosphodiesterase 4 triggers ovulation in follicle-stimulating hormone-primed rats Endocrinology 146 2005 208 214 (Pubitemid 40051741)
21. P.E. Losco, F.M. Poulet, G.Z. Kaminska-McNamara, and M.F. Klein Myocardial and reproductive system toxicity of SCH 351591, a selective phosphodiesterase-4 inhibitor, in CD-1 mice Toxicol Pathol 38 2010 568 582
22. G. Pincus, and E.V. Enzmann The comparative behavior of mammalian eggs in vivo and in vitro. I. The activation of ovarian eggs J Exp Med 62 1935 665 675
23. R.G. Edwards Maturation in vitro of mouse, sheep, cow, pig, rhesus monkey and human ovarian oocytes Nature 208 1965 349 351
24. J.J. Eppig, R.R. Freter, P.F. Ward-Bailey, and R.M. Schultz Inhibition of oocyte maturation in the mouse: participation of cAMP, steroid hormones and a putative maturation-inhibitory factor Dev Biol 100 1983 39 49 (Pubitemid 14238254)
25. E.A. Bornslaeger, M.W. Wilde, and R.M. Schultz Regulation of mouse oocyte maturation: involvement of cyclic AMP phosphodiesterase and calmodulin Dev Biol 105 1984 488 499
26. K. Shitsukawa, C.B. Andersen, F.J. Richard, A.K. Horner, A. Wiersma, M. van Duin, and M. Conti Cloning and characterization of the cyclic guanosine monophosphate-inhibited phosphodiesterase PDE3A expressed in mouse oocyte Biol Reprod 65 2001 188 196 (Pubitemid 32574799)
27. F.J. Richard, A. Tsafriri, and M. Conti Role of phosphodiesterase type 3A in rat oocyte maturation Biol Reprod 65 2001 1444 1451 (Pubitemid 33031502)
28. V.C. Manganiello, C.J. Smith, E. Degerman, and P. Belfrage Cyclic GMP-inhibited cyclic nucleotide phosphodiesterase JJ 1990 87 116
29. E. Degerman, P. Belfrage, and V.C. Manganiello Structure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3) J Biol Chem 272 1997 6823 6826 (Pubitemid 27166373)
30. D.H. Maurice, and R.J. Haslam Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP Mol Pharmacol 37 1990 671 681 (Pubitemid 20171502)
31. A. Tsafriri, S.Y. Chun, R. Zhang, A.J. Hsueh, and M. Conti Oocyte maturation involves compartmentalization and opposing changes of cAMP levels in follicular somatic and germ cells: studies using selective phosphodiesterase inhibitors Dev Biol 178 1996 393 402 (Pubitemid 26365046)
32. R.E. Thomas, D.T. Armstrong, and R.B. Gilchrist Differential effects of specific phosphodiesterase isoenzyme inhibitors on bovine oocyte meiotic maturation Dev Biol 244 2002 215 225 (Pubitemid 34450638)
33. M.A. Mayes, and M.A. Sirard Effect of type 3 and type 4 phosphodiesterase inhibitors on the maintenance of bovine oocytes in meiotic arrest Biol Reprod 66 2002 180 184 (Pubitemid 34020601)
34. C.B. Andersen, R.A. Roth, and M. Conti Protein kinase B/Akt induces resumption of meiosis in Xenopus oocytes J Biol Chem 273 1998 18705 18708 (Pubitemid 28366252)
35. M. Sasseville, N. Cote, C. Guillemette, and F.J. Richard New insight into the role of phosphodiesterase 3A in porcine oocyte maturation BMC Dev Biol 6 2006 47
36. J.T. Jensen, K.M. Schwinof, M.B. Zelinski-Wooten, M. Conti, L.V. DePaolo, and R.L. Stouffer Phosphodiesterase 3 inhibitors selectively block the spontaneous resumption of meiosis by macaque oocytes in vitro Hum Reprod 17 2002 2079 2084
37. D. Nogueira, R. Cortvrindt, B. Everaerdt, and J. Smitz Effects of long-term in vitro exposure to phosphodiesterase type-3 inhibitors on follicle and oocyte development Reproduction 130 2005 177 186 (Pubitemid 41149805)
38. S. Masciarelli, K. Horner, C. Liu, S.H. Park, M. Hinckley, S. Hockman, T. Nedachi, C. Jin, M. Conti, and V. Manganiello Cyclic nucleotide phosphodiesterase 3A-deficient mice as a model of female infertility J Clin Invest 114 2004 196 205 (Pubitemid 39071624)
39. A. Wiersma, B. Hirsch, A. Tsafriri, R.G. Hanssen, M. Van de Kant, H.J. Kloosterboer, M. Conti, and A.J. Hsueh Phosphodiesterase 3 inhibitors suppress oocyte maturation and consequent pregnancy without affecting ovulation and cyclicity in rodents J Clin Invest 102 1998 532 537 (Pubitemid 28376156)
40. C.B. Andersen, H. Sakaue, T. Nedachi, K.S. Kovacina, C. Clayberger, M. Conti, and R.A. Roth Protein kinase B/Akt is essential for the insulin- but not progesterone-stimulated resumption of meiosis in Xenopus oocytes Biochem J 369 2003 227 238 (Pubitemid 36174192)
41. S.J. Han, S. Vaccari, T. Nedachi, C.B. Andersen, K.S. Kovacina, R.A. Roth, and M. Conti Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation EMBO J 25 2006 5716 5725 (Pubitemid 44967755)
42. R.P. Norris, W.J. Ratzan, M. Freudzon, L.M. Mehlmann, J. Krall, M.A. Movsesian, H. Wang, H. Ke, V.O. Nikolaev, and L.A. Jaffe Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte Development 136 2009 1869 1878
43. J. Tornell, H. Billig, and T. Hillensjo Resumption of rat oocyte meiosis is paralleled by a decrease in guanosine 3′,5′-cyclic monophosphate (cGMP) and is inhibited by microinjection of cGMP Acta Physiol Scand 139 1990 511 517 (Pubitemid 20249323)
44. J. Tornell, M. Brannstrom, and T. Hillensjo Different effects of cyclic nucleotide derivatives upon the rat oocyte-cumulus complex in vitro Acta Physiol Scand 122 1984 507 513 (Pubitemid 15197444)
45. A. Tsafriri, S.H. Pomerantz, and C.P. Channing Inhibition of oocyte maturation by porcine follicular fluid: partial characterization of the inhibitor Biol Reprod 14 1976 511 516
46. M. Zhang, Y.Q. Su, K. Sugiura, G. Xia, and J.J. Eppig Granulosa cell ligand NPPC and its receptor NPR2 maintain meiotic arrest in mouse oocytes Science 330 2010 366 369