PDE1 isozymes, key regulators of pathological vascular remodeling

Current Opinion in Pharmacology

Volumn 11, Issue 6, 2011, Pages 720-724

  Chan, Stefan ^a   Yan, Chen ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLIC AMP; CYCLIC GMP; MYOSIN LIGHT CHAIN; NITRIC OXIDE; PHOSPHODIESTERASE 1A; PHOSPHODIESTERASE 1B; PHOSPHODIESTERASE 1C; PHOSPHODIESTERASE I; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL PROLIFERATION; COLLAGEN DEGRADATION; ENDOTHELIUM CELL; HUMAN; MYOFIBROBLAST; NONHUMAN; PATHOLOGICAL VASCULAR REMODELING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PULMONARY HYPERTENSION; UPREGULATION; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE;

EID: 82255162733     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2011.09.002     Document Type: Review

References (52)

1. S. Heeneman, J.C. Sluimer, and M.JaP. Daemen Angiotensin-converting enzyme and vascular remodeling Circ Res 101 2007 441 454 (Pubitemid 47347875)
2. D.M. Lloyd-Jones, and K.D. Bloch The vascular biology of nitric oxide and its role in atherogenesis Annu Rev Med 47 1996 365 375 (Pubitemid 26138897)
3. R. Ross The pathogenesis of atherosclerosis: a perspective for the 1990s Nature 362 1993 801 809 (Pubitemid 23132154)
4. G.K. Owens Regulation of differentiation of vascular smooth muscle cells Physiol Rev 75 1995 487 517
5. R. Ross Rous-Whipple award lecture. Atherosclerosis: a defense mechanism gone awry Am J Pathol 143 1993 987 1002 (Pubitemid 24070539)
6. A. Forte, A. Della Corte, M. De Feo, F. Cerasuolo, and M. Cipollaro Role of myofibroblasts in vascular remodelling: focus on restenosis and aneurysm Cardiovasc Res 88 2010 395 405
7. A. Schober, and A. Zernecke Chemokines in vascular remodeling Thromb Haemost 97 2007 730 737 (Pubitemid 46779958)
8. P. Libby, P.M. Ridker, and A. Maseri Inflammation and atherosclerosis Circulation 105 2002 1135 1143 (Pubitemid 34212626)
9. K. Maiellaro, and W.R. Taylor The role of the adventitia in vascular inflammation Cardiovasc Res 75 2007 640 648 (Pubitemid 47238746)
10. E.J. Tsai, and D.A. Kass Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics Pharmacol Ther 122 2009 216 238
11. X. Cullere, S.K. Shaw, L. Andersson, J. Hirahashi, F.W. Luscinskas, and T.N. Mayadas Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase Blood 105 2005 1950 1955 (Pubitemid 40731777)
12. R.C. Hewer, G.B. Sala-Newby, Y.J. Wu, A.C. Newby, and M. Bond PKA and Epac synergistically inhibit smooth muscle cell proliferation J Mol Cell Cardiol 50 2011 87 98
13. M. Biel, and S. Michalakis Cyclic nucleotide-gated channels Handb Exp Pharmacol 191 2009 111 136
14. K.T. Cheng, F.L. Chan, Y. Huang, W.Y. Chan, and X. Yao Expression of olfactory-type cyclic nucleotide-gated channel (CNGA2) in vascular tissues Histochem Cell Biol 120 2003 475 481 (Pubitemid 38058202)
15. X. Yao, P.S. Leung, H.Y. Kwan, T.P. Wong, and M.W. Fong Rod-type cyclic nucleotide-gated cation channel is expressed in vascular endothelium and vascular smooth muscle cells Cardiovasc Res 41 1999 282 290 (Pubitemid 29016068)
16. Y. Cai, C.L. Miller, D.J. Nagel, K.-I. Jeon, S. Lim, P. Gao, Pa. Knight, and C. Yan Cyclic nucleotide phosphodiesterase 1 regulates lysosome-dependent type I collagen protein degradation in vascular smooth muscle cells Arterioscler Thromb Vasc Biol 31 2011 616 623
17. T. Aizawa, H. Wei, J.M. Miano, J. Abe, B.C. Berk, and C. Yan Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells Circ Res 93 2003 406 413 (Pubitemid 37100005)
18. G. Vandecasteele, I. Verde, C. Rucker-Martin, and P. Donzeau-Gouge Fischmeister R: cyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytes J Physiol 533 2001 329 340 (Pubitemid 32519991)
19. A.T. Bender, and J.A. Beavo Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use Pharmacol Rev 58 2006 488 520 (Pubitemid 44394910)
20. J.A. Beavo Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms Physiol Rev 75 1995 725 748
21. D. Kim, S.D. Rybalkin, X. Pi, Y. Wang, C. Zhang, T. Munzel, J.A. Beavo, B.C. Berk, and C. Yan Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance Circulation 104 2001 2338 2343 (Pubitemid 33049518)
22. C.R. Molina, J.W. Andresen, R.M. Rapoport, S. Waldman, and F. Murad Effect of in vivo nitroglycerin therapy on endothelium-dependent and independent vascular relaxation and cyclic GMP accumulation in rat aorta J Cardiovasc Pharmacol 10 1987 371 378 (Pubitemid 17153826)
23. R.K. Jaiswal Endothelin inhibits the atrial natriuretic factor stimulated cGMP production by activating the protein kinase C in rat aortic smooth muscle cells Biochem Biophys Res Commun 182 1992 395 402
24. C.L. Miller, M. Oikawa, Y. Cai, A.P. Wojtovich, D.J. Nagel, X. Xu, H. Xu, V. Florio, S.D. Rybalkin, and J.A. Beavo Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy Circ Res 105 2009 956 964
25. D.J. Nagel, T. Aizawa, K.-I. Jeon, W. Liu, A. Mohan, H. Wei, J.M. Miano, Va. Florio, P. Gao, and Va. Korshunov Role of nuclear Ca2+/calmodulin-stimulated phosphodiesterase 1A in vascular smooth muscle cell growth and survival Circ Res 98 2006 777 784
26. A.T. Bender, C.L. Ostenson, D. Giordano, and Ja. Beavo Differentiation of human monocytes in vitro with granulocyte, Ämacrophage colony-stimulating factor and macrophage colony-stimulating factor produces distinct changes in cGMP phosphodiesterase expression Cell Signal 16 2004 365 374 (Pubitemid 37542411)
27. S.D. Rybalkin, K.E. Bornfeldt, W.K. Sonnenburg, I.G. Rybalkina, K.S. Kwak, K. Hanson, E.G. Krebs, and J.A. Beavo Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype J Clin Invest 100 1997 2611 2621 (Pubitemid 27514902)
28. F. Murray, H.H. Patel, R.Y.S. Suda, S. Zhang, Pa. Thistlethwaite, J.X.J. Yuan, and Pa. Insel Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1 Am J Physiol Lung Cell Mol Physiol 292 2007 L294 L303
29. P. Han, J. Werber, M. Surana, N. Fleischer, and T. Michaeli The calcium/calmodulin-dependent phosphodiesterase PDE1C down-regulates glucose-induced insulin secretion J Biol Chem 274 1999 22337 22344
30. T.R. Dunkern, and A. Hatzelmann Characterization of inhibitors of phosphodiesterase 1C on a human cellular system FEBS J 274 2007 4812 4824 (Pubitemid 47353125)
31. C. Lugnier, and V.B. Schini Characterization of cyclic nucleotide phosphodiesterases from cultured bovine aortic endothelial cells Biochem Pharmacol 39 1990 75 84 (Pubitemid 20027972)
32. Y. Kishi, T. Ashikaga, and F. Numano Phosphodiesterases in vascular endothelial cells Adv Second Messenger Phosphoprotein Res 25 1992 201 213
33. S.J. Netherton, and D.H. Maurice Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis Mol Pharmacol 67 2005 263 272 (Pubitemid 40069987)
34. T. Ashikaga, S.J. Strada, and W.J. Thompson Altered expression of cyclic nucleotide phosphodiesterase isozymes during culture of aortic endothelial cells Biochem Pharmacol 54 1997 1071 1079 (Pubitemid 27479020)
35. J. Wang, S. Bingaman, and V.H. Huxley Intrinsic sex-specific differences in microvascular endothelial cell phosphodiesterases Am J Physiol Heart Circ Physiol 298 2010 H1146 H1154
36. F.R. Giachini, V.V. Lima, F.S. Carneiro, R.C. Tostes, and R.C. Webb Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1 Hypertension 57 2011 655 663
37. K.-I. Jeon, H. Jono, C.L. Miller, Y. Cai, S. Lim, X. Liu, P. Gao, J.-I. Abe, J.-D. Li, and C. Yan Ca2+/calmodulin-stimulated PDE1 regulates the beta-catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells FEBS J 277 2010 5026 5039
38. H.-Y. Zhou, W.-D. Chen, D.-L. Zhu, L.-Y. Wu, J. Zhang, W.-Q. Han, J.-D. Li, C. Yan, and P.-J. Gao The PDE1A-PKCalpha signaling pathway is involved in the upregulation of alpha-smooth muscle actin by TGF-beta1 in adventitial fibroblasts J Vasc Res 47 2010 9 15
39. A.T. Bender, C.L. Ostenson, E.H. Wang, and J.A. Beavo Selective up-regulation of PDE1B2 upon monocyte-to-macrophage differentiation Proc Natl Acad Sci U S A 102 2005 497 502 (Pubitemid 40116795)
40. S.D. Rybalkin, I. Rybalkina, J.A. Beavo, and K.E. Bornfeldt Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation Circ Res 90 2002 151 157 (Pubitemid 34627083)
41. M. Humbert, N.W. Morrell, S.L. Archer, K.R. Stenmark, M.R. Maclean, B. Sc, I.M. Lang, B.W. Christman, E.K. Weir, and O. Eickelberg Cellular and molecular pathobiology of pulmonary arterial hypertension J Am Coll Cardiol 43 2004 13S 24S (Pubitemid 38759713)
42. M.R. Maclean, E.D. Johnston, K.M. McCulloch, L. Pooley, M.D. Houslay, and G. Sweeney Phosphodiesterase isoforms in the pulmonary arterial circulation of the rat: changes in pulmonary hypertension J Pharmacol Exp Ther 283 1997 619 624 (Pubitemid 27514618)
43. X. Tao, Y.-J. Zhang, F.-M. Shen, Y.-F. Guan, and D.-F. Su Fosinopril prevents the pulmonary arterial remodeling in sinoaortic-denervated rats by regulating phosphodiesterase J Cardiovasc Pharmacol 51 2008 24 31
44. R.T. Schermuly, C. Inholte, H.A. Ghofrani, H. Gall, N. Weissmann, A. Weidenbach, W. Seeger, and F. Grimminger Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors Respir Res 6 2005 76
45. P.G. Phillips, L. Long, M.R. Wilkins, and N.W. Morrell cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling American Journal of Physiology. Lung Cellular and Molecular Physiology 288 2005 L103 L115
46. O.V. Evgenov, C.J. Busch, N.V. Evgenov, R. Liu, B. Petersen, G.E. Falkowski, B. Petho, Am. Vas, K.D. Bloch, and W.M. Zapol Inhibition of phosphodiesterase 1 augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs with acute pulmonary hypertension American Journal of Physiology. Lung Cellular and Molecular Physiology 290 2006 L723 L729
47. A.E. Medina, T.E. Krahe, and A.S. Ramoa Restoration of neuronal plasticity by a phosphodiesterase type 1 inhibitor in a model of fetal alcohol exposure J Neurosci 26 2006 1057 1060 (Pubitemid 43237096)
48. R. Deshmukh, V. Sharma, S. Mehan, N. Sharma, and K.L. Bedi Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine - a PDE1 inhibitor Eur J Pharmacol 620 2009 49 56
49. T.E. Krahe, W. Wang, and A.E. Medina Phosphodiesterase inhibition increases CREB phosphorylation and restores orientation selectivity in a model of fetal alcohol spectrum disorders PLoS One 4 2009 e6643
50. P. Bonoczk, B. Gulyas, V. Adam-Vizi, A. Nemes, E. Karpati, B. Kiss, M. Kapas, C. Szantay, I. Koncz, and T. Zelles Role of sodium channel inhibition in neuroprotection: effect of vinpocetine Brain Res Bull 53 2000 245 254
51. K.-I. Jeon, X. Xu, T. Aizawa, J.H. Lim, H. Jono, D.-S. Kwon, J.-I. Abe, B.C. Berk, J.-D. Li, and C. Yan Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism Proc Natl Acad Sci U S A 107 2010 9795 9800
52. G. Szilagyi, Z. Nagy, L. Balkay, I. Boros, M. Emri, S. Lehel, T. Marian, T. Molnar, S. Szakall, and L. Tron Effects of vinpocetine on the redistribution of cerebral blood flow and glucose metabolism in chronic ischemic stroke patients: a PET study J Neurol Sci 229-230 2005 275 284 (Pubitemid 40341594)