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Volumn 2, Issue FEB, 2011, Pages

Systemic effector and regulatory immune responses to chlamydial antigens in trachomatous trichiasis

Author keywords

Chlamydia trachomatis; Immune response; Interferon gamma; NK cells; Trachoma; Tregs

Indexed keywords


EID: 82155184199     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2011.00010     Document Type: Article
Times cited : (21)

References (75)
  • 1
    • 33847163271 scopus 로고    scopus 로고
    • CD4(+)CD25(-) Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
    • Anderson, C. F., Oukka, M., Kuchroo, V. J., and Sacks, D. (2007). CD4(+)CD25(-) Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J. Exp. Med. 204, 285-297.
    • (2007) J. Exp. Med. , vol.204 , pp. 285-297
    • Anderson, C.F.1    Oukka, M.2    Kuchroo, V.J.3    Sacks, D.4
  • 2
    • 0033374375 scopus 로고    scopus 로고
    • The duration of human ocular Chlamydia trachomatis infection is age dependent
    • Bailey, R., Duong, T., Carpenter, R., Whittle, H., and Mabey, D. (1999). The duration of human ocular Chlamydia trachomatis infection is age dependent. Epidemiol. Infect. 123, 479-486.
    • (1999) Epidemiol. Infect. , vol.123 , pp. 479-486
    • Bailey, R.1    Duong, T.2    Carpenter, R.3    Whittle, H.4    Mabey, D.5
  • 3
    • 0028912614 scopus 로고
    • Subjects recovering from human ocular chlamydial infection have enhanced lymphoproliferative responses to chlamydial antigens compared with those of persistently diseased controls
    • Bailey, R. L., Holland, M. J., Whittle, H. C., and Mabey, D. C. (1995). Subjects recovering from human ocular chlamydial infection have enhanced lymphoproliferative responses to chlamydial antigens compared with those of persistently diseased controls. Infect. Immun. 63, 389-392.
    • (1995) Infect. Immun. , vol.63 , pp. 389-392
    • Bailey, R.L.1    Holland, M.J.2    Whittle, H.C.3    Mabey, D.C.4
  • 4
    • 39249084174 scopus 로고    scopus 로고
    • In silico identification and in vivo analysis of a novel T-cell antigen from Chlamydia
    • Barker, C. J., Beagley, K. W., Hafner, L. M., and Timms, P. (2008). In silico identification and in vivo analysis of a novel T-cell antigen from Chlamydia, NrdB. Vaccine 26, 1285-1296.
    • (2008) NrdB. Vaccine , vol.26 , pp. 1285-1296
    • Barker, C.J.1    Beagley, K.W.2    Hafner, L.M.3    Timms, P.4
  • 5
    • 67649138829 scopus 로고    scopus 로고
    • Regulatory T cells in the control of host-microorganism interactions (*)
    • Belkaid, Y., and Tarbell, K. (2009). Regulatory T cells in the control of host-microorganism interactions (*). Annu. Rev. Immunol. 27, 551-589.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 551-589
    • Belkaid, Y.1    Tarbell, K.2
  • 6
    • 0026543619 scopus 로고
    • The statistical analysis of data from immunoepidemiological studies
    • Bennett, S., and Riley, E. M. (1992). The statistical analysis of data from immunoepidemiological studies. J. Immunol. Methods 146, 229-239.
    • (1992) J. Immunol. Methods , vol.146 , pp. 229-239
    • Bennett, S.1    Riley, E.M.2
  • 7
    • 77956932834 scopus 로고    scopus 로고
    • Delaying bacillus Calmette-Guerin vaccination from birth to 4 1/2 months of age reduces postvaccination Th1 and IL-17 responses but leads to comparable mycobacterial responses at 9 months of age
    • Burl, S., Adetifa, U. J., Cox, M., Touray, E., Ota, M. O., Marchant, A., Whittle, H., McShane, H., Rowland-Jones, S. L., and Flanagan, K. L. (2010). Delaying bacillus Calmette-Guerin vaccination from birth to 4 1/2 months of age reduces postvaccination Th1 and IL-17 responses but leads to comparable mycobacterial responses at 9 months of age. J. Immunol. 185, 2620-2628.
    • (2010) J. Immunol. , vol.185 , pp. 2620-2628
    • Burl, S.1    Adetifa, U.J.2    Cox, M.3    Touray, E.4    Ota, M.O.5    Marchant, A.6    Whittle, H.7    McShane, H.8    Rowland-Jones, S.L.9    Flanagan, K.L.10
  • 9
    • 9244263031 scopus 로고    scopus 로고
    • Cytokine and fibrogenic gene expression in the conjunctivas of subjects from a Gambian community where trachoma is endemic
    • Burton, M. J., Bailey, R. L., Jeffries, D., Mabey, D. C., and Holland, M. J. (2004). Cytokine and fibrogenic gene expression in the conjunctivas of subjects from a Gambian community where trachoma is endemic. Infect. Immun. 72, 7352-7356.
    • (2004) Infect. Immun. , vol.72 , pp. 7352-7356
    • Burton, M.J.1    Bailey, R.L.2    Jeffries, D.3    Mabey, D.C.4    Holland, M.J.5
  • 15
    • 0028845224 scopus 로고
    • Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection
    • Cotter, T. W., Meng, Q., Shen, Z. L., Zhang, Y. X., Su, H., and Caldwell, H. D. (1995). Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection. Infect. Immun. 63, 4704-4714.
    • (1995) Infect. Immun. , vol.63 , pp. 4704-4714
    • Cotter, T.W.1    Meng, Q.2    Shen, Z.L.3    Zhang, Y.X.4    Su, H.5    Caldwell, H.D.6
  • 17
    • 33748348172 scopus 로고    scopus 로고
    • Conjunctival FOXP3 expression in trachoma: do regulatory T cells have a role in human ocular Chlamydia trachomatis infection?
    • doi: 10.1371/ journal.pmed.0030266
    • Faal, N., Bailey, R. L., Jeffries, D., Joof, H., Sarr, I., Laye, M., Mabey, D. C., and Holland, M. J. (2006). Conjunctival FOXP3 expression in trachoma: do regulatory T cells have a role in human ocular Chlamydia trachomatis infection? PLoS Med. 3, e266. doi: 10.1371/ journal.pmed.0030266
    • (2006) PLoS Med , vol.3
    • Faal, N.1    Bailey, R.L.2    Jeffries, D.3    Joof, H.4    Sarr, I.5    Laye, M.6    Mabey, D.C.7    Holland, M.J.8
  • 19
    • 74249118677 scopus 로고    scopus 로고
    • Phenotypic analysis of human peripheral blood regulatory T cells (CD4+FOXP3+CD127lo/-) ex vivo and after in vitro restimulation with malaria antigens
    • Finney, O. C., Riley, E. M., and Walther, M. (2010). Phenotypic analysis of human peripheral blood regulatory T cells (CD4+FOXP3+CD127lo/-) ex vivo and after in vitro restimulation with malaria antigens. Eur. J. Immunol. 40, 47-60.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 47-60
    • Finney, O.C.1    Riley, E.M.2    Walther, M.3
  • 22
    • 9144249657 scopus 로고    scopus 로고
    • Human CD8+ T cells recognize the 60-kDa cysteine-rich outer membrane protein from Chlamydia trachomatis
    • Gervassi, A. L., Grabstein, K. H., Probst, P., Hess, B., Alderson, M. R., and Fling, S. P. (2004). Human CD8+ T cells recognize the 60-kDa cysteine-rich outer membrane protein from Chlamydia trachomatis. J. Immunol. 173, 6905-6913.
    • (2004) J. Immunol. , vol.173 , pp. 6905-6913
    • Gervassi, A.L.1    Grabstein, K.H.2    Probst, P.3    Hess, B.4    Alderson, M.R.5    Fling, S.P.6
  • 23
    • 70249099278 scopus 로고    scopus 로고
    • T cell responses in the absence of IFN-gamma exacerbate uterine infection with Chlamydia trachomatis
    • Gondek, D. C., Roan, N. R., and Starnbach, M. N. (2009). T cell responses in the absence of IFN-gamma exacerbate uterine infection with Chlamydia trachomatis. J. Immunol. 183, 1313-1319.
    • (2009) J. Immunol. , vol.183 , pp. 1313-1319
    • Gondek, D.C.1    Roan, N.R.2    Starnbach, M.N.3
  • 24
    • 0035657276 scopus 로고    scopus 로고
    • Recognition of the 60 kilodalton cysteine-rich outer membrane protein OMP2 by CD4(+) T cells from humans infected with Chlamydia trachomatis
    • Goodall, J. C., Beacock-Sharp, H., Deane, K. H., and Gaston, J. S. (2001a). Recognition of the 60 kilodalton cysteine-rich outer membrane protein OMP2 by CD4(+) T cells from humans infected with Chlamydia trachomatis. Clin. Exp. Immunol. 126, 488-493.
    • (2001) Clin. Exp. Immunol. , vol.126 , pp. 488-493
    • Goodall, J.C.1    Beacock-Sharp, H.2    Deane, K.H.3    Gaston, J.S.4
  • 25
    • 0035017003 scopus 로고    scopus 로고
    • Identification of Chlamydia trachomatis antigens recognized by human CD4+ T lymphocytes by screening an expression library
    • Goodall, J. C., Yeo, G., Huang, M., Raggiaschi, R., and Gaston, J. S. (2001b). Identification of Chlamydia trachomatis antigens recognized by human CD4+ T lymphocytes by screening an expression library. Eur. J. Immunol. 31, 1513-1522.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1513-1522
    • Goodall, J.C.1    Yeo, G.2    Huang, M.3    Raggiaschi, R.4    Gaston, J.S.5
  • 26
    • 5644302161 scopus 로고    scopus 로고
    • Human T regulatory cells can use the perforin pathway to cause autologous target cell death
    • Grossman, W. J., Verbsky, J. W., Barchet, W., Colonna, M., Atkinson, J. P., and Ley, T. J. (2004). Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity 21, 589-601.
    • (2004) Immunity , vol.21 , pp. 589-601
    • Grossman, W.J.1    Verbsky, J.W.2    Barchet, W.3    Colonna, M.4    Atkinson, J.P.5    Ley, T.J.6
  • 28
    • 0029846656 scopus 로고    scopus 로고
    • T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring
    • Holland, M. J., Bailey, R. L., Conway, D. J., Culley, F., Miranpuri, G., Byrne, G. I., Whittle, H. C., and Mabey, D. C. (1996). T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring. Clin. Exp. Immunol. 105, 429-435.
    • (1996) Clin. Exp. Immunol. , vol.105 , pp. 429-435
    • Holland, M.J.1    Bailey, R.L.2    Conway, D.J.3    Culley, F.4    Miranpuri, G.5    Byrne, G.I.6    Whittle, H.C.7    Mabey, D.C.8
  • 29
    • 0027524749 scopus 로고
    • Conjunctival scarring in trachoma is associated with depressed cell-mediated immune responses to chlamydial antigens
    • Holland, M. J., Bailey, R. L., Hayes, L. J., Whittle, H. C., and Mabey, D. C. (1993). Conjunctival scarring in trachoma is associated with depressed cell-mediated immune responses to chlamydial antigens. J. Infect. Dis. 168, 1528-1531.
    • (1993) J. Infect. Dis. , vol.168 , pp. 1528-1531
    • Holland, M.J.1    Bailey, R.L.2    Hayes, L.J.3    Whittle, H.C.4    Mabey, D.C.5
  • 31
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., Nomura, T., and Sakaguchi, S. (2003). Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 32
    • 78049382659 scopus 로고    scopus 로고
    • NK cells as effectors of acquired immune responses: effector CD4+ T cell-dependent activation of NK cells following vaccination
    • Horowitz, A., Behrens, R. H., Okell, L., Fooks, A. R., and Riley, E. M. (2010a). NK cells as effectors of acquired immune responses: effector CD4+ T cell-dependent activation of NK cells following vaccination. J. Immunol. 185, 2808-2818.
    • (2010) J. Immunol. , vol.185 , pp. 2808-2818
    • Horowitz, A.1    Behrens, R.H.2    Okell, L.3    Fooks, A.R.4    Riley, E.M.5
  • 33
    • 77953380103 scopus 로고    scopus 로고
    • Cross-talk between T cells and NK cells generates rapid effector responses to Plasmodium falciparum-infected erythrocytes
    • Horowitz, A., Newman, K. C., Evans, J. H., Korbel, D. S., Davis, D. M., and Riley, E. M. (2010b). Cross-talk between T cells and NK cells generates rapid effector responses to Plasmodium falciparum-infected erythrocytes. J. Immunol. 184, 6043-6052.
    • (2010) J. Immunol. , vol.184 , pp. 6043-6052
    • Horowitz, A.1    Newman, K.C.2    Evans, J.H.3    Korbel, D.S.4    Davis, D.M.5    Riley, E.M.6
  • 34
    • 77449154111 scopus 로고    scopus 로고
    • Activation of human NK cells by malaria-infected red blood cells
    • Horowitz, A., and Riley, E. M. (2010). Activation of human NK cells by malaria-infected red blood cells. Methods Mol. Biol. 612, 429-446.
    • (2010) Methods Mol. Biol. , vol.612 , pp. 429-446
    • Horowitz, A.1    Riley, E.M.2
  • 37
    • 85047690488 scopus 로고    scopus 로고
    • An integrated view of suppressor T cell subsets in immunoregulation
    • Jiang, H., and Chess, L. (2004). An integrated view of suppressor T cell subsets in immunoregulation. J. Clin. Invest. 114, 1198-1208.
    • (2004) J. Clin. Invest. , vol.114 , pp. 1198-1208
    • Jiang, H.1    Chess, L.2
  • 38
    • 67649201737 scopus 로고    scopus 로고
    • Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine
    • Kari, L., Whitmire, W. M., Crane, D. D., Reveneau, N., Carlson, J. H., Goheen, M. M., Peterson, E. M., Pal, S., de la Maza, L. M., and Caldwell, H. D. (2009). Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine. J. Immunol. 182, 8063-8070.
    • (2009) J. Immunol. , vol.182 , pp. 8063-8070
    • Kari, L.1    Whitmire, W.M.2    Crane, D.D.3    Reveneau, N.4    Carlson, J.H.5    Goheen, M.M.6    Peterson, E.M.7    Pal, S.8    de la Maza, L.M.9    Caldwell, H.D.10
  • 39
    • 34548181388 scopus 로고    scopus 로고
    • Activation-induced expression of CD56 by T cells is associated with a reprogramming of cytolytic activity and cytokine secretion profile in vitro
    • Kelly-Rogers, J., Madrigal-Estebas, L., O'Connor, T., and Doherty, D. G. (2006). Activation-induced expression of CD56 by T cells is associated with a reprogramming of cytolytic activity and cytokine secretion profile in vitro. Hum. Immunol. 67, 863-873.
    • (2006) Hum. Immunol. , vol.67 , pp. 863-873
    • Kelly-Rogers, J.1    Madrigal-Estebas, L.2    O'Connor, T.3    Doherty, D.G.4
  • 40
    • 0035425496 scopus 로고    scopus 로고
    • Epitope clusters in the major outer membrane protein of Chlamydia trachomatis
    • Kim, S. K., and DeMars, R. (2001). Epitope clusters in the major outer membrane protein of Chlamydia trachomatis. Curr. Opin. Immunol. 13, 429-436.
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 429-436
    • Kim, S.K.1    DeMars, R.2
  • 41
    • 0029079615 scopus 로고
    • Chlamydia trachomatis A peptide of shown to be a primary T-cell epitope in vitro induces cell-mediated immunity in vivo
    • Knight, S. C., Iqball, S., Woods, C., Stagg, A., Ward, M. E., and Tuffrey, M. (1995). Chlamydia trachomatis A peptide of shown to be a primary T-cell epitope in vitro induces cell-mediated immunity in vivo. Immunology 85, 8-15.
    • (1995) Immunology , vol.85 , pp. 8-15
    • Knight, S.C.1    Iqball, S.2    Woods, C.3    Stagg, A.4    Ward, M.E.5    Tuffrey, M.6
  • 42
    • 69149094927 scopus 로고    scopus 로고
    • Mechanism of human natural killer cell activation by Haemophilus ducreyi
    • Li, W., Janowicz, D. M., Fortney, K. R., Katz, B. P., and Spinola, S. M. (2009). Mechanism of human natural killer cell activation by Haemophilus ducreyi. J. Infect. Dis. 200, 590-598.
    • (2009) J. Infect. Dis. , vol.200 , pp. 590-598
    • Li, W.1    Janowicz, D.M.2    Fortney, K.R.3    Katz, B.P.4    Spinola, S.M.5
  • 43
    • 59449109417 scopus 로고    scopus 로고
    • Characterization of the recognition and functional heterogeneity exhibited by cytokine-induced killer cell subsets against acute myeloid leukaemia target cell
    • Linn, Y. C., Lau, S. K., Liu, B. H., Ng, L. H., Yong, H. X., and Hui, K. M. (2009). Characterization of the recognition and functional heterogeneity exhibited by cytokine-induced killer cell subsets against acute myeloid leukaemia target cell. Immunology 126, 423-435.
    • (2009) Immunology , vol.126 , pp. 423-435
    • Linn, Y.C.1    Lau, S.K.2    Liu, B.H.3    Ng, L.H.4    Yong, H.X.5    Hui, K.M.6
  • 45
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy, K. J., and Powrie, F. (2001). Regulatory T cells in the control of immune pathology. Nat. Immunol. 2, 816-822.
    • (2001) Nat. Immunol. , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 46
    • 66149151068 scopus 로고    scopus 로고
    • Trachoma: global magnitude of a preventable cause of blindness
    • Mariotti, S. P., Pascolini, D., and Rose-Nussbaumer, J. (2009). Trachoma: global magnitude of a preventable cause of blindness. Br. J. Ophthalmol. 93, 563-568.
    • (2009) Br. J. Ophthalmol. , vol.93 , pp. 563-568
    • Mariotti, S.P.1    Pascolini, D.2    Rose-Nussbaumer, J.3
  • 48
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
    • McGuirk, P., McCann, C., and Mills, K. H. (2002). Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J. Exp. Med. 195, 221-231.
    • (2002) J. Exp. Med. , vol.195 , pp. 221-231
    • McGuirk, P.1    McCann, C.2    Mills, K.H.3
  • 50
    • 78049419276 scopus 로고    scopus 로고
    • Human conjunctival transcriptome analysis reveals the prominence of innate defense in Chlamydia trachomatis infection
    • Natividad, A., Freeman, T. C., Jeffries, D., Burton, M. J., Mabey, D. C., Bailey, R. L., and Holland, M. J. (2010). Human conjunctival transcriptome analysis reveals the prominence of innate defense in Chlamydia trachomatis infection. Infect. Immun. 78, 4895-4911.
    • (2010) Infect. Immun. , vol.78 , pp. 4895-4911
    • Natividad, A.1    Freeman, T.C.2    Jeffries, D.3    Burton, M.J.4    Mabey, D.C.5    Bailey, R.L.6    Holland, M.J.7
  • 53
    • 34447263785 scopus 로고    scopus 로고
    • Functional Foxp3+ CD4+ CD25(bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection
    • Nesburn, A. B., Bettahi, I., Dasgupta, G., Chentoufi, A. A., Zhang, X., You, S., Morishige, N., Wahlert, A. J., Brown, D. J., Jester, J. V., Wechsler, S. L., and BenMohamed, L. (2007). Functional Foxp3+ CD4+ CD25(bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection. J. Virol. 81, 7647-7661.
    • (2007) J. Virol. , vol.81 , pp. 7647-7661
    • Nesburn, A.B.1    Bettahi, I.2    Dasgupta, G.3    Chentoufi, A.A.4    Zhang, X.5    You, S.6    Morishige, N.7    Wahlert, A.J.8    Brown, D.J.9    Jester, J.V.10    Wechsler, S.L.11    BenMohamed, L.12
  • 54
    • 17444414236 scopus 로고    scopus 로고
    • GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily
    • Nocentini, G., and Riccardi, C. (2005). GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily. Eur. J. Immunol. 35, 1016-1022.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 1016-1022
    • Nocentini, G.1    Riccardi, C.2
  • 55
    • 78049304748 scopus 로고    scopus 로고
    • Adaptive evolution of the Chlamydia trachomatis dominant antigen reveals distinct evolutionary scenarios for B-and T-cell epitopes: worldwide survey
    • doi: 10.1371/journal. pone.0013171
    • Nunes, A., Nogueira, P. J., Borrego, M. J., and Gomes, J. P. (2010). Adaptive evolution of the Chlamydia trachomatis dominant antigen reveals distinct evolutionary scenarios for B-and T-cell epitopes: worldwide survey. PLoS ONE 5, e13171. doi: 10.1371/journal. pone.0013171
    • (2010) PLoS ONE , vol.5
    • Nunes, A.1    Nogueira, P.J.2    Borrego, M.J.3    Gomes, J.P.4
  • 56
    • 38449095531 scopus 로고    scopus 로고
    • Identification of human T cell targets recognized during Chlamydia trachomatis genital infection
    • Olsen, A. W., Follmann, F., Hojrup, P., Leah, R., Sand, C., Andersen, P., and Theisen, M. (2007). Identification of human T cell targets recognized during Chlamydia trachomatis genital infection. J. Infect. Dis. 196, 1546-1552.
    • (2007) J. Infect. Dis. , vol.196 , pp. 1546-1552
    • Olsen, A.W.1    Follmann, F.2    Hojrup, P.3    Leah, R.4    Sand, C.5    Andersen, P.6    Theisen, M.7
  • 57
    • 33750296372 scopus 로고    scopus 로고
    • Identification of CT521 as a frequent target of Th1 cells in patients with urogenital Chlamydia trachomatis infection
    • Olsen, A. W., Follmann, F., Jensen, K., Hojrup, P., Leah, R., Sorensen, H., Hoffmann, S., Andersen, P., and Theisen, M. (2006). Identification of CT521 as a frequent target of Th1 cells in patients with urogenital Chlamydia trachomatis infection. J. Infect. Dis. 194, 1258-1266.
    • (2006) J. Infect. Dis. , vol.194 , pp. 1258-1266
    • Olsen, A.W.1    Follmann, F.2    Jensen, K.3    Hojrup, P.4    Leah, R.5    Sorensen, H.6    Hoffmann, S.7    Andersen, P.8    Theisen, M.9
  • 58
    • 77956279310 scopus 로고    scopus 로고
    • Protection against Chlamydia promoted by a subunit vaccine (CTH1) compared with a primary intranasal infection in a mouse genital challenge model
    • doi: 10.1371/journal.pone.0010768
    • Olsen, A. W., Theisen, M., Christensen, D., Follmann, F., and Andersen, P. (2010). Protection against Chlamydia promoted by a subunit vaccine (CTH1) compared with a primary intranasal infection in a mouse genital challenge model. PLoS ONE 5, e10768. doi: 10.1371/journal.pone.0010768
    • (2010) PLoS ONE , vol.5
    • Olsen, A.W.1    Theisen, M.2    Christensen, D.3    Follmann, F.4    Andersen, P.5
  • 59
    • 70349906776 scopus 로고    scopus 로고
    • Chlamydia vaccine candidates and tools for chlamydial antigen discovery
    • Rockey, D. D., Wang, J., Lei, L., and Zhong, G. (2009). Chlamydia vaccine candidates and tools for chlamydial antigen discovery. Expert Rev. Vaccines 8, 1365-1377.
    • (2009) Expert Rev. Vaccines , vol.8 , pp. 1365-1377
    • Rockey, D.D.1    Wang, J.2    Lei, L.3    Zhong, G.4
  • 60
    • 77958116988 scopus 로고    scopus 로고
    • Characterization of humoral immune responses to chlamydial heat shock protein 60, protease-like activity factor and hypothetical protein CT795 in inflammatory and severe trachoma
    • Skwor, T., Kandel, R. P., Basravi, S., Khan, A., Sharma, B., and Dean, D. (2010). Characterization of humoral immune responses to chlamydial heat shock protein 60, protease-like activity factor and hypothetical protein CT795 in inflammatory and severe trachoma. Invest. Ophthalmol. Vis. Sci. 51, 5128-5136.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 5128-5136
    • Skwor, T.1    Kandel, R.P.2    Basravi, S.3    Khan, A.4    Sharma, B.5    Dean, D.6
  • 61
    • 9244223651 scopus 로고    scopus 로고
    • Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity
    • Stock, P., Akbari, O., Berry, G., Freeman, G. J., Dekruyff, R. H., and Umetsu, D. T. (2004). Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nat. Immunol. 5, 1149-1156.
    • (2004) Nat. Immunol. , vol.5 , pp. 1149-1156
    • Stock, P.1    Akbari, O.2    Berry, G.3    Freeman, G.J.4    Dekruyff, R.H.5    Umetsu, D.T.6
  • 62
    • 1642305619 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells control the severity of viral immunoinflammatory lesions
    • Suvas, S., Azkur, A. K., Kim, B. S., Kumaraguru, U., and Rouse, B. T. (2004). CD4(+)CD25(+) regulatory T cells control the severity of viral immunoinflammatory lesions. J. Immunol. 172, 4123-4132.
    • (2004) J. Immunol. , vol.172 , pp. 4123-4132
    • Suvas, S.1    Azkur, A.K.2    Kim, B.S.3    Kumaraguru, U.4    Rouse, B.T.5
  • 63
    • 33846925025 scopus 로고    scopus 로고
    • Discovery of a vaccine antigen that protects mice from Chlamydia pneumoniae infection
    • Thorpe, C., Edwards, L., Snelgrove, R., Finco, O., Rae, A., Grandi, G., Guilio, R., and Hussell, T. (2007). Discovery of a vaccine antigen that protects mice from Chlamydia pneumoniae infection. Vaccine 25, 2252-2260.
    • (2007) Vaccine , vol.25 , pp. 2252-2260
    • Thorpe, C.1    Edwards, L.2    Snelgrove, R.3    Finco, O.4    Rae, A.5    Grandi, G.6    Guilio, R.7    Hussell, T.8
  • 66
    • 15544372354 scopus 로고    scopus 로고
    • Human leukocyte antigen and cytokine gene variants as predictors of recurrent Chlamydia trachomatis infection in high-risk adolescents
    • Wang, C., Tang, J., Geisler, W. M., Crowley-Nowick, P. A., Wilson, C. M., and Kaslow, R. A. (2005). Human leukocyte antigen and cytokine gene variants as predictors of recurrent Chlamydia trachomatis infection in high-risk adolescents. J. Infect. Dis. 191, 1084-1092.
    • (2005) J. Infect. Dis. , vol.191 , pp. 1084-1092
    • Wang, C.1    Tang, J.2    Geisler, W.M.3    Crowley-Nowick, P.A.4    Wilson, C.M.5    Kaslow, R.A.6
  • 67
    • 65049091364 scopus 로고    scopus 로고
    • A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice
    • Wang, J., Chen, L., Chen, F., Zhang, X., Zhang, Y., Baseman, J., Perdue, S., Yeh, I. T., Shain, R., Holland, M., Bailey, R., Mabey, D., Yu, P., and Zhong, G. (2009). A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice. Vaccine 27, 2967-2980.
    • (2009) Vaccine , vol.27 , pp. 2967-2980
    • Wang, J.1    Chen, L.2    Chen, F.3    Zhang, X.4    Zhang, Y.5    Baseman, J.6    Perdue, S.7    Yeh, I.T.8    Shain, R.9    Holland, M.10    Bailey, R.11    Mabey, D.12    Yu, P.13    Zhong, G.14
  • 68
    • 77956408136 scopus 로고    scopus 로고
    • A genome-wide profiling of the humoral immune response to Chlamydia trachomatis infection reveals vaccine candidate antigens expressed in humans
    • Wang, J., Zhang, Y., Lu, C., Lei, L., Yu, P., and Zhong, G. (2010). A genome-wide profiling of the humoral immune response to Chlamydia trachomatis infection reveals vaccine candidate antigens expressed in humans. J. Immunol. 185, 1670-1680.
    • (2010) J. Immunol. , vol.185 , pp. 1670-1680
    • Wang, J.1    Zhang, Y.2    Lu, C.3    Lei, L.4    Yu, P.5    Zhong, G.6
  • 69
    • 0032751041 scopus 로고    scopus 로고
    • IFN-gamma knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection
    • Wang, S., Fan, Y., Brunham, R. C., and Yang, X. (1999). IFN-gamma knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection. Eur. J. Immunol. 29, 3782-3792.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 3782-3792
    • Wang, S.1    Fan, Y.2    Brunham, R.C.3    Yang, X.4
  • 71
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • Wynn, T. A. (2004). Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat. Rev. Immunol. 4, 583-594.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 583-594
    • Wynn, T.A.1
  • 72
    • 0037247570 scopus 로고    scopus 로고
    • Role of cytokines in Chlamydia trachomatis protective immunity and immunopathology
    • Yang, X. (2003). Role of cytokines in Chlamydia trachomatis protective immunity and immunopathology. Curr. Pharm. Des. 9, 67-73.
    • (2003) Curr. Pharm. Des. , vol.9 , pp. 67-73
    • Yang, X.1
  • 73
    • 0033556174 scopus 로고    scopus 로고
    • IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection
    • Yang, X., Gartner, J., Zhu, L., Wang, S., and Brunham, R. C. (1999). IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection. J. Immunol. 162, 1010-1017.
    • (1999) J. Immunol. , vol.162 , pp. 1010-1017
    • Yang, X.1    Gartner, J.2    Zhu, L.3    Wang, S.4    Brunham, R.C.5
  • 74
    • 0030747201 scopus 로고    scopus 로고
    • DNA vaccination with the major outer-membrane protein gene induces acquired immunity to Chlamydia trachomatis (mouse pneumonitis) infection
    • Zhang, D., Yang, X., Berry, J., Shen, C., McClarty, G., and Brunham, R. C. (1997). DNA vaccination with the major outer-membrane protein gene induces acquired immunity to Chlamydia trachomatis (mouse pneumonitis) infection. J. Infect. Dis. 176, 1035-1040.
    • (1997) J. Infect. Dis. , vol.176 , pp. 1035-1040
    • Zhang, D.1    Yang, X.2    Berry, J.3    Shen, C.4    McClarty, G.5    Brunham, R.C.6
  • 75
    • 4043147851 scopus 로고    scopus 로고
    • B7-CD28 interaction promotes proliferation and survival but suppresses differentiation of CD4-CD8-T cells in the thymus
    • Zheng, X., Gao, J. X., Chang, X., Wang, Y., Liu, Y., Wen, J., Zhang, H., Zhang, J., and Zheng, P. (2004). B7-CD28 interaction promotes proliferation and survival but suppresses differentiation of CD4-CD8-T cells in the thymus. J. Immunol. 173, 2253-2261
    • (2004) J. Immunol. , vol.173 , pp. 2253-2261
    • Zheng, X.1    Gao, J.X.2    Chang, X.3    Wang, Y.4    Liu, Y.5    Wen, J.6    Zhang, H.7    Zhang, J.8    Zheng, P.9


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