Antioxidants protect against reactive oxygen species associated with adriamycin-treated cardiomyocytes

Cancer Letters

Volumn 136, Issue 1, 1999, Pages 41-46

  Deatley, S Michael ^a   Aksenov, Michael Y ^a,b   Aksenova, Marina V ^a   Harris, Bart ^a   Hadley, Robert ^a   Cole Harper, Pamela ^a   Carney, John M ^a,c   Butterfield, D Allan ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c EVOTEC AG   (Germany)

Author keywords

Adriamycin; Antioxidants; Cardiotoxicity; Free radicals

Indexed keywords

ANTIOXIDANT; DOXORUBICIN; FLUORESCEIN DERIVATIVE; MESALAZINE; N TERT BUTYL ALPHA PHENYLNITRONE; OXYGEN RADICAL; PROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; TROLOX C;

ANIMAL CELL; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; FLUORESCENCE; HEART MUSCLE CELL; HEART PROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIOXIDANTS; CHROMANS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; FLUORESCEINS; HEART; MESALAMINE; MYOCARDIUM; NITROGEN OXIDES; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES;

EID: 0033040251     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00306-1     Document Type: Article

References (39)

1. Weiss R.B., Sarosy G., Clagett-Carr K., Russo M., Leyland-Jones B. Anthracycline analogs: the past, present, and future. Cancer Chemother. Pharmacol. 18:1986;185-197.
2. Arena E., Arico M., Biondo F., Dusonchet N., Gebbia L., Gerbasi F., Sanguedolce R., Rausa L. Analysis of some probable factors responsible for adriamycin-induced cardiotoxicity. 2nd International Symposium on Adriamycin. 1974;Belgium European Press, Medikon. pp. 160-172.
3. Lefrak E.A., Pitha J., Rosenheim S., Gottlieb J.A. A clinicopathologic analysis of adriamycin cardiotoxicity. Cancer. 32:1973;302-314.
4. Doroshow J.H., Locker G.Y. Role of oxygen radical formation in anthracycline cardiac toxicity. Muggia F.M., Young C.W., Carter S.K. Anthracycline Antibiotics in Cancer Therapy. 1982;317 Martinus Nijhoff, Le Hague.
5. Doroshow J.H. Effect of anthracycline antibiotics on oxygen radical formation in rat heart. Cancer Res. 43:1983;460-472.
6. Myers C.E. The role of free radical damage in the genesis of doxorubicin cardiac toxicity. Muggia F.M., Young C.W., Carter S.K. Anthracycline Antibiotics in Cancer Chemotherapy. 1982;297 Martinus Nijhoff, The Hague.
7. Olson R.D., Boert R.C., Gerber J.G., Niles A.S. Mechanism of adriamycin cardiotoxicity: Evidence for oxidative stress. Life Sci. 29:1981;1393-1401.
8. DeAtley S.M., Aksenov M.Y., Aksenova M.V., Carney J.M., Butterfield D.A. Adriamycin induces protein oxidation in erythrocyte membranes. Pharmacol. Toxicol. 1998;. in press.
9. Butterfield D.A., Stadtman E.R. Protein oxidation processes in aging brain. Mattson M.P., Geddes J.W. The Aging Brain. 1997;161 JAI Press, Greenwich.
10. Myers C.E., McGuire W.P., Liss R.H., Ifrim I., Grotzinger K., Young R.C. Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response. Science. 197:1977;165-167.
11. Singal P.K., Tong J.G. Vitamin E deficiency accentuates adriamycin-induced cardiomyopathy and cell surface changes. Mol. Cell. Biochem. 84:1988;163-171.
12. Hermansen K., Wasserman K. The effect of vitamin E and selenium on doxorubicin (Adriamycin) induced delayed toxicity in mice. Acta Pharmacol. Toxicol. 58:1986;31-37.
13. Van Vleet J.F., Ferrans V.J., Weirich W.E. Cardiac disease induced by chronic adriamycin administration in dogs and an evaluation of vitamin E and selenium as cardioprotectants. Am. J. Pathol. 99:1980;13-42.
14. Breed J., Zimmerman A., Dormans J., Pinedo H.M. Failure of the antioxidant vitamin E to protect against adriamycin-induced cardiotoxicity in the rabbit. Cancer Res. 40:1980;2033-2038.
15. Villani F., Galimberti M., Monti E., Piccinini F., Lanza E., Rozza A., Favalli L., Poggi P., Zunino F. Effect of glutathione and N-acetylcysteine on in vitro and in vivo cardiac toxicity of doxorubicin. Free Radical Res. Commun. 11:1990;145-151.
16. Paracchini L., Jotti A., Bottiroli G., Prosperi E., Supino R., Piccinini F. The spin trap alpha-phenyl-tert-butyl nitrone protects against myelotoxicity and cardiotoxicity of adriamycin while preserving the cytotoxic activity. Anticancer Res. 13:1993;1607-1612.
17. Siveski-Iliskovic N., Thomas T.P., Kaul N., Slezak J., Singal P.K. Probucol protects against adriamycin cardiomyopathy without interfering with its anti-tumor properties. Circulation. 91:1995;10-15.
18. Sarvazyan N. Visualization of doxorubicin-induced oxidative stress in isolated cardiac myocytes. Am. J. Physiol. 271:1996;H2079-H2085.
19. Kimes B.W., Brandt B.L. Properties of a clonal muscle cell line from rat heart. Exp. Cell Res. 98:1976;367-381.
20. Zhu H., Bannenberg G.L., Moldeus P., Shertzer H.G. Oxidation pathways for the intracellular probe 2′7′-dichlorofluorescein. Arch. Toxicol. 68:1994;582-587.
21. Hsieh H.J., Cheng C.C., Wu S.T., Chiu J.J., Wung B.S., Wang D.L. Increase of reactive oxygen species (ROS) in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression. J. Cell. Physiol. 175:1998;156-162.
22. Ruiz-munoz L.M., Vidal-Vanaclocha F., Lampreabe I. Enalprilat inhibits hydrogen peroxide production by murine mesangial cells exposed to high glucose concentrations. Nephrol. Dial. Transplant. 12:1997;456-464.
23. Ishibashi M., Akazawa S., Sakamaki H., Matsumoto K., Yamasaki H., Yamaguchi Y., Goto S., Urata Y., Kondo T., Nagataki S. Oxygen-induced embryopathy and the significance of glutathione-dependent antioxidant system in the rat embryo during early organogenesis. Free Rad. Biol. Med. 22:1997;447-454.
24. Perez-Garcia F., Marin E., Canigueral S., Adzet T. Anti-inflammatory action of Pluchea sagittalis: involvement of an antioxidant mechanism. Life Sci. 59:1996;2033-2040.
25. Harris M.E., Hensley K., Butterfield D.A., Leedle R.A., Carney J.M. Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons. Exp. Neurol. 131:1995;193-202.
26. Ubezio P., Civoli F. Flow cytometric detection of hydrogen peroxide production induced by doxorubicin in cancer cells. Free Rad. Biol. Med. 16:1994;509-516.
27. Gille L., Nohl H. Analyses of the molecular mechanism of adriamycin-induced cardiotoxicity. Free Rad. Biol. 23:1997;775-782.
28. Griffin-Green E.A., Zaleska M.M., Erecinska M. Adriamycin-induced lipid peroxidation in mitochondria and microsomes. Biochem. Pharmacol. 37:1988;3071-3077.
29. Marcillat O., Zhang Y., Davies K.J. Oxidative and non-oxidative mechanism in the inactivation of cardiac mitochondrial electron transport chain components by doxorubicin. Biochem. J. 259:1989;181-189.
30. Olson R.D., Mushlin P.S. Mechanisms of anthracycline cardiotoxicity: are metabolites involved? Acosta D. Focus on Molecular, Cellular and In Vitro Toxicology. 1990;51 CRC Press, Boca Raton, FL.
31. Eckenhoff R.G., Somlyo A.P. Cardiac mitochondrial calcium content during fatal doxorubicin toxicity. Toxicol. Appl. Pharmacol. 97:1989;167-172.
32. Solem L.E., Henry T.R., Wallace K.B. Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration. Toxicol. Appl. Pharmacol. 129:1994;214-222.
33. 2+ binding and lipid peroxidation but depresses myocardial function. Am. J. Physiol. 250:1986;H419-H425.
34. Subramaniam R., Roediger F., Jordan B., Mattson M.P., Keller J.N., Waeg G., Butterfield D.A. The lipid peroxidation product, 4-hydroxy-2-trans-nonenal, alters the conformation of cortical synaptosomal membrane proteins. J. Neurochem. 69:1997;1161-1169.
35. Allgayer H., Hofer P., Schmidt M., Bohne P., Kruis W., Gugler R. Superoxide, hydroxyl and fatty acid radical scavenging by aminosalicylates. Direct evaluation with electron spin resonance spectroscopy. Biochem. Pharmacol. 43:1992;259-262.
36. Pearson D.C., Jourd'heuil D., Meddings J.B. The anti-oxidant properties of 5-aminosalicylic acid. Free Rad. Biol. Med. 21:1996;367-373.
37. Hall N.C., Carney J.M., Cheng M., Butterfield D.A. Prevention of ischemia/reperfusion-induced alterations in synaptosomal membrane-associated proteins and lipids by n-tert-butyl-alpha-phenylnitrone and difluoromethylornithine. Neuroscience. 69:1995;591-600.
38. Howard B.J., Yatin S., Hensley K., Allen K.L., Kelly J.P., Carney J.M., Butterfield D.A. Prevention of hyperoxia-induced alterations in synaptosomal membrane-associated by n-tert-butyl-alpha-phenylnitrone and 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl (tempo). J. Neurochem. 67:1996;2045-2050.
39. Butterfield D.A., Howard B.J., Yatin S., Allen K.L., Carney J.M. Free radical oxidation of brain proteins in accelerated senescence and its modulation by n-tert-butyl-alpha-phenylnitrone. Proc. Natl. Acad. Sci. USA. 94:1997;674-678.