-
1
-
-
0031039888
-
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β
-
Kuiper GG, Carlsson B, Grandien K, Enmark E, Häggblad J, Nilsson S, Gustafsson JA 1997 Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 138:863-870
-
(1997)
Endocrinology
, vol.138
, pp. 863-870
-
-
Kuiper, G.G.1
Carlsson, B.2
Grandien, K.3
Enmark, E.4
Häggblad, J.5
Nilsson, S.6
Gustafsson, J.A.7
-
2
-
-
0030593681
-
ERβ: Identification and characterization of a novel human estrogen receptor
-
Mosselman S, Polman J, Dijkema R 1996 ERβ: identification and characterization of a novel human estrogen receptor. FEBS Lett 392:49-53
-
(1996)
FEBS Lett
, vol.392
, pp. 49-53
-
-
Mosselman, S.1
Polman, J.2
Dijkema, R.3
-
3
-
-
18844429222
-
Reflections on the discovery and significance of estrogen receptor β
-
Koehler KF, Helguero LA, Haldosén LA, Warner M, Gustafsson JA 2005 Reflections on the discovery and significance of estrogen receptor β. Endocr Rev 26:465-478
-
(2005)
Endocr Rev
, vol.26
, pp. 465-478
-
-
Koehler, K.F.1
Helguero, L.A.2
Haldosén, L.A.3
Warner, M.4
Gustafsson, J.A.5
-
4
-
-
33846018559
-
Estrogen receptor-β: Recent lessons from in vivo studies
-
Harris HA 2007 Estrogen receptor-β: recent lessons from in vivo studies. Mol Endocrinol 21:1-13
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1-13
-
-
Harris, H.A.1
-
6
-
-
78649335764
-
Selectively targeting estrogen receptors for cancer treatment
-
Shanle EK, Xu W 2010 Selectively targeting estrogen receptors for cancer treatment. Adv Drug Deliv Rev 62:1265-1276
-
(2010)
Adv Drug Deliv Rev
, vol.62
, pp. 1265-1276
-
-
Shanle, E.K.1
Xu, W.2
-
7
-
-
0035050785
-
Role of estrogen receptor β in estrogen action
-
Pettersson K, Gustafsson JA 2001 Role of estrogen receptor β in estrogen action. Annu Rev Physiol 63:165-192
-
(2001)
Annu Rev Physiol
, vol.63
, pp. 165-192
-
-
Pettersson, K.1
Gustafsson, J.A.2
-
8
-
-
73549104043
-
Genome-wide dynamics of chromatin binding of estrogen receptors α and β: Mutual restriction and competitive site selection
-
Charn TH, Liu ET, Chang EC, Lee YK, Katzenellenbogen JA, Katzenellenbogen BS 2010 Genome-wide dynamics of chromatin binding of estrogen receptors α and β: mutual restriction and competitive site selection. Mol Endocrinol 24:47-59
-
(2010)
Mol Endocrinol
, vol.24
, pp. 47-59
-
-
Charn, T.H.1
Liu, E.T.2
Chang, E.C.3
Lee, Y.K.4
Katzenellenbogen, J.A.5
Katzenellenbogen, B.S.6
-
10
-
-
0030747070
-
Mouse estrogen receptor β forms estrogen response element-binding heterodimers with estrogen receptor α
-
Pettersson K, Grandien K, Kuiper GG, Gustafsson JA 1997 Mouse estrogen receptor β forms estrogen response element-binding heterodimers with estrogen receptor α. Mol Endocrinol 11:1486-1496
-
(1997)
Mol Endocrinol
, vol.11
, pp. 1486-1496
-
-
Pettersson, K.1
Grandien, K.2
Kuiper, G.G.3
Gustafsson, J.A.4
-
11
-
-
0037040967
-
Differential modulation of DNA conformation by estrogen receptors α and β
-
Schultz JR, Loven MA, Melvin VM, Edwards DP, Nardulli AM 2002 Differential modulation of DNA conformation by estrogen receptors α and β. J Biol Chem 277:8702-8707
-
(2002)
J Biol Chem
, vol.277
, pp. 8702-8707
-
-
Schultz, J.R.1
Loven, M.A.2
Melvin, V.M.3
Edwards, D.P.4
Nardulli, A.M.5
-
13
-
-
43049090857
-
Estrogen receptorsα andβ as determinants of gene expression: Influence of ligand, dose, and chromatin binding
-
Chang EC, Charn TH, Park SH, Helferich WG, Komm B, Katzenellenbogen JA, Katzenellenbogen BS 2008 Estrogen receptorsα andβ as determinants of gene expression: influence of ligand, dose, and chromatin binding. Mol Endocrinol 22:1032-1043
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1032-1043
-
-
Chang, E.C.1
Charn, T.H.2
Park, S.H.3
Helferich, W.G.4
Komm, B.5
Katzenellenbogen, J.A.6
Katzenellenbogen, B.S.7
-
14
-
-
0037314762
-
Estrogen receptor (ER)-β reduces ERα-regulated gene transcription, supporting a "ying yang" relationship between ERα and ERβ in mice
-
Lindberg MK, Movérare S, Skrtic S, Gao H, Dahlman-Wright K, Gustafsson JA, Ohlsson C 2003 Estrogen receptor (ER)-β reduces ERα-regulated gene transcription, supporting a "ying yang" relationship between ERα and ERβ in mice. Mol Endocrinol 17:203-208
-
(2003)
Mol Endocrinol
, vol.17
, pp. 203-208
-
-
Lindberg, M.K.1
Movérare, S.2
Skrtic, S.3
Gao, H.4
Dahlman-Wright, K.5
Gustafsson, J.A.6
Ohlsson, C.7
-
15
-
-
0037397074
-
Monitoring protein-protein interactions using split synthetic renilla luciferase protein-fragmentassisted complementation
-
Paulmurugan R, Gambhir SS 2003 Monitoring protein-protein interactions using split synthetic renilla luciferase protein-fragmentassisted complementation. Anal Chem 75:1584-1589
-
(2003)
Anal Chem
, vol.75
, pp. 1584-1589
-
-
Paulmurugan, R.1
Gambhir, S.S.2
-
16
-
-
14744281422
-
Firefly luciferase enzyme fragment complementation for imaging in cells and living animals
-
Paulmurugan R, Gambhir SS 2005 Firefly luciferase enzyme fragment complementation for imaging in cells and living animals. Anal Chem 77:1295-1302
-
(2005)
Anal Chem
, vol.77
, pp. 1295-1302
-
-
Paulmurugan, R.1
Gambhir, S.S.2
-
17
-
-
33750483267
-
An intramolecular folding sensor for imaging estrogen receptor-ligand interactions
-
Paulmurugan R, Gambhir SS 2006 An intramolecular folding sensor for imaging estrogen receptor-ligand interactions. Proc Natl Acad Sci USA 103:15883-15888
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15883-15888
-
-
Paulmurugan, R.1
Gambhir, S.S.2
-
18
-
-
46349084349
-
A human estrogen receptor (ER)α mutation with differential responsiveness to nonsteroidal ligands: Novel approaches for studying mechanism of ER action
-
Paulmurugan R, Tamrazi A, Katzenellenbogen JA, Katzenellenbogen BS, Gambhir SS 2008 A human estrogen receptor (ER)α mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action. Mol Endocrinol 22:1552-1564
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1552-1564
-
-
Paulmurugan, R.1
Tamrazi, A.2
Katzenellenbogen, J.A.3
Katzenellenbogen, B.S.4
Gambhir, S.S.5
-
19
-
-
0036908594
-
Estrogen receptor dimerization: Ligand binding regulates dimer affinity and dimer dissociation rate
-
Tamrazi A, Carlson KE, Daniels JR, Hurth KM, Katzenellenbogen JA 2002 Estrogen receptor dimerization: ligand binding regulates dimer affinity and dimer dissociation rate. Mol Endocrinol 16: 2706-2719
-
(2002)
Mol Endocrinol
, vol.16
, pp. 2706-2719
-
-
Tamrazi, A.1
Carlson, K.E.2
Daniels, J.R.3
Hurth, K.M.4
Katzenellenbogen, J.A.5
-
20
-
-
0034727853
-
Pyrazole ligands: Structure-affinity/activity relationships and estrogen receptor- α-selective agonists
-
Stauffer SR, Coletta CJ, Tedesco R, Nishiguchi G, Carlson K, Sun J, Katzenellenbogen BS, Katzenellenbogen JA 2000 Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor- α-selective agonists. J Med Chem 43:4934-4947
-
(2000)
J Med Chem
, vol.43
, pp. 4934-4947
-
-
Stauffer, S.R.1
Coletta, C.J.2
Tedesco, R.3
Nishiguchi, G.4
Carlson, K.5
Sun, J.6
Katzenellenbogen, B.S.7
Katzenellenbogen, J.A.8
-
21
-
-
0036177151
-
Antagonists selective for estrogen receptor α
-
Sun J, Huang YR, Harrington WR, Sheng S, Katzenellenbogen JA, Katzenellenbogen BS 2002 Antagonists selective for estrogen receptor α. Endocrinology 143:941-947
-
(2002)
Endocrinology
, vol.143
, pp. 941-947
-
-
Sun, J.1
Huang, Y.R.2
Harrington, W.R.3
Sheng, S.4
Katzenellenbogen, J.A.5
Katzenellenbogen, B.S.6
-
22
-
-
0035935731
-
Estrogen receptor-β potency-selective ligands: Structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues
-
Meyers MJ, Sun J, Carlson KE, Marriner GA, Katzenellenbogen BS, Katzenellenbogen JA 2001 Estrogen receptor-β potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem 44: 4230-4251
-
(2001)
J Med Chem
, vol.44
, pp. 4230-4251
-
-
Meyers, M.J.1
Sun, J.2
Carlson, K.E.3
Marriner, G.A.4
Katzenellenbogen, B.S.5
Katzenellenbogen, J.A.6
-
23
-
-
1542319924
-
Equol, a natural estrogenic metabolite from soy isoflavones: Convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors α and β
-
Muthyala RS, Ju YH, Sheng S, Williams LD, Doerge DR, Katzenellenbogen BS, Helferich WG, Katzenellenbogen JA 2004 Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors α and β. Bioorg Med Chem 12:1559-1567
-
(2004)
Bioorg Med Chem
, vol.12
, pp. 1559-1567
-
-
Muthyala, R.S.1
Ju, Y.H.2
Sheng, S.3
Williams, L.D.4
Doerge, D.R.5
Katzenellenbogen, B.S.6
Helferich, W.G.7
Katzenellenbogen, J.A.8
-
24
-
-
0344417000
-
Estrogen receptor subtype-selective ligands: Asymmetric synthesis and biological evaluation of cis- and trans- 5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes
-
Meyers MJ, Sun J, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA 1999 Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans- 5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes. J Med Chem 42: 2456-2468
-
(1999)
J Med Chem
, vol.42
, pp. 2456-2468
-
-
Meyers, M.J.1
Sun, J.2
Carlson, K.E.3
Katzenellenbogen, B.S.4
Katzenellenbogen, J.A.5
-
25
-
-
77955417371
-
A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography
-
Massoud TF, Paulmurugan R, Gambhir SS 2010 A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography. Nat Med 16:921-926
-
(2010)
Nat Med
, vol.16
, pp. 921-926
-
-
Massoud, T.F.1
Paulmurugan, R.2
Gambhir, S.S.3
-
26
-
-
0033305438
-
Estrogen receptor null mice: What have we learned and where will they lead us?
-
Couse JF, Korach KS 1999 Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev 20:358-417
-
(1999)
Endocr Rev
, vol.20
, pp. 358-417
-
-
Couse, J.F.1
Korach, K.S.2
-
27
-
-
0037180571
-
Noninvasive im-aging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies
-
Paulmurugan R, Umezawa Y, Gambhir SS 2002 Noninvasive im-aging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies. Proc Natl Acad Sci USA 99:15608-15613
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15608-15613
-
-
Paulmurugan, R.1
Umezawa, Y.2
Gambhir, S.S.3
-
28
-
-
0021327660
-
Estrogen receptor synthesis and turnover in MCF-7 breast cancer cells measured by a density shift technique
-
Eckert RL, Mullick A, Rorke EA, Katzenellenbogen BS 1984 Estrogen receptor synthesis and turnover in MCF-7 breast cancer cells measured by a density shift technique. Endocrinology 114: 629-637
-
(1984)
Endocrinology
, vol.114
, pp. 629-637
-
-
Eckert, R.L.1
Mullick, A.2
Rorke, E.A.3
Katzenellenbogen, B.S.4
-
29
-
-
0036234964
-
Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism
-
Shiau AK, Barstad D, Radek JT, Meyers MJ, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA, Agard DA, Greene GL 2002 Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat Struct Biol 9:359-364
-
(2002)
Nat Struct Biol
, vol.9
, pp. 359-364
-
-
Shiau, A.K.1
Barstad, D.2
Radek, J.T.3
Meyers, M.J.4
Nettles, K.W.5
Katzenellenbogen, B.S.6
Katzenellenbogen, J.A.7
Agard, D.A.8
Greene, G.L.9
-
30
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, SchützG, Umesono K, Blumberg B, Kastner P, Mark M, Chambon P, Evans RM 1995 The nuclear receptor superfamily: the second decade. Cell 83:835-839
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schütz, G.5
Umesono, K.6
Blumberg, B.7
Kastner, P.8
Mark, M.9
Chambon, P.10
Evans, R.M.11
-
31
-
-
77949409085
-
A dual estrogen receptor TR-FRET assay for simultaneous measurement of steroid site binding and coactivator recruitment
-
Hilal T, Puetter V, Otto C, Parczyk K, Bader B 2010 A dual estrogen receptor TR-FRET assay for simultaneous measurement of steroid site binding and coactivator recruitment. J Biomol Screen 15: 268-278
-
(2010)
J Biomol Screen
, vol.15
, pp. 268-278
-
-
Hilal, T.1
Puetter, V.2
Otto, C.3
Parczyk, K.4
Bader, B.5
-
32
-
-
0348110368
-
Molecular sensors of estrogen receptor conformations and dynamics
-
Tamrazi A, Carlson KE, Katzenellenbogen JA 2003 Molecular sensors of estrogen receptor conformations and dynamics. Mol Endocrinol 17:2593-2602
-
(2003)
Mol Endocrinol
, vol.17
, pp. 2593-2602
-
-
Tamrazi, A.1
Carlson, K.E.2
Katzenellenbogen, J.A.3
-
33
-
-
22344450551
-
Coactivator proteins as determinants of estrogen receptor structure and function: Spectroscopic evidence for a novel coactivator-stabilized receptor conformation
-
Tamrazi A, Carlson KE, Rodriguez AL, Katzenellenbogen JA 2005 Coactivator proteins as determinants of estrogen receptor structure and function: spectroscopic evidence for a novel coactivator-stabilized receptor conformation. Mol Endocrinol 19:1516-1528
-
(2005)
Mol Endocrinol
, vol.19
, pp. 1516-1528
-
-
Tamrazi, A.1
Carlson, K.E.2
Rodriguez, A.L.3
Katzenellenbogen, J.A.4
-
34
-
-
34547896679
-
Measuring ligand-dependent and ligand-independent interactions between nuclear receptors and associated proteins using bioluminescence resonance energy transfer (BRET)
-
Koterba KL, Rowan BG 2006 Measuring ligand-dependent and ligand-independent interactions between nuclear receptors and associated proteins using bioluminescence resonance energy transfer (BRET). Nucl Recept Signal 4:e021
-
(2006)
Nucl Recept Signal
, vol.e021
, pp. 4
-
-
Koterba, K.L.1
Rowan, B.G.2
-
35
-
-
34247898925
-
Raloxifene and ICI182,780 increase estrogen receptor-α association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12
-
Lupien M, Jeyakumar M, Hébert E, Hilmi K, Cotnoir-White D, Loch C, Auger A, Dayan G, Pinard GA, Wurtz JM, Moras D, Katzenellenbogen J, Mader S 2007 Raloxifene and ICI182,780 increase estrogen receptor-α association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12. Mol Endocrinol 21:797-816
-
(2007)
Mol Endocrinol
, vol.21
, pp. 797-816
-
-
Lupien, M.1
Jeyakumar, M.2
Hébert, E.3
Hilmi, K.4
Cotnoir-White, D.5
Loch, C.6
Auger, A.7
Dayan, G.8
Pinard, G.A.9
Wurtz, J.M.10
Moras, D.11
Katzenellenbogen, J.12
Mader, S.13
-
36
-
-
57749105457
-
Intermolecular interactions identify ligandselective activity of estrogen receptor α/β dimers
-
Powell E, Xu W 2008 Intermolecular interactions identify ligandselective activity of estrogen receptor α/β dimers. Proc Natl Acad Sci U S A 105:19012-19017
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19012-19017
-
-
Powell, E.1
Xu, W.2
-
37
-
-
33947380192
-
Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions
-
Paulmurugan R, Gambhir SS 2007 Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions. Anal Chem 79:2346-2353
-
(2007)
Anal Chem
, vol.79
, pp. 2346-2353
-
-
Paulmurugan, R.1
Gambhir, S.S.2
-
38
-
-
1542615075
-
Molecular imaging of drug-modulated protein-protein interactions in living subjects
-
Paulmurugan R, Massoud TF, Huang J, Gambhir SS 2004 Molecular imaging of drug-modulated protein-protein interactions in living subjects. Cancer Res 64:2113-2119
-
(2004)
Cancer Res
, vol.64
, pp. 2113-2119
-
-
Paulmurugan, R.1
Massoud, T.F.2
Huang, J.3
Gambhir, S.S.4
|