AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-β-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway

Biochemical Pharmacology

Volumn 80, Issue 8, 2010, Pages 1210-1220

  Chang, Mei Ying ^a   Ho, Feng Ming ^b,c   Wang, Jang Shiun ^a   Kang, Hao Cheng ^a   Chang, Yung ^c   Ye, Zhi Xian ^a   Lin, Wan Wan ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAO YUAN GENERAL HOSPITAL   (Taiwan)

^c CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

AMPK; COX 2; P38; TAK1

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; 5' IODOTUBERCIDIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLOOXYGENASE 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTACYCLIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUBERCIDIN DERIVATIVE; UNCLASSIFIED DRUG; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; RIBONUCLEOTIDE;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL TYPE; CONTROLLED STUDY; DRUG ACTIVITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL LINE; CYCLOOXYGENASE 2; ENDOTHELIAL CELLS; EPOPROSTENOL; GENE EXPRESSION REGULATION; HUMANS; MACROPHAGES; MAP KINASE KINASE KINASES; MICE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RIBONUCLEOTIDES; SIGNAL TRANSDUCTION;

EID: 77956229580     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.06.049     Document Type: Article

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