-
1
-
-
0037064542
-
The role of soluble receptors in cytokine biology: The agonistic properties of the sIL-6R/IL-6 complex
-
DOI 10.1016/S0167-4889(02)00319-1, PII S0167488902003191
-
Jones S. A., Rose-John S., The role of soluble receptors in cytokine biology: the agonistic properties of the sIL-6R/IL-6 complex Biochimica et Biophysica Acta 2002 1592 3 251 263 (Pubitemid 35284882)
-
(2002)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1592
, Issue.3
, pp. 251-263
-
-
Jones, S.A.1
Rose-John, S.2
-
2
-
-
0030891228
-
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment
-
DOI 10.1016/S1074-7613(00)80334-9
-
Romano M., Sironi M., Toniatti C., Polentarutti N., Fruscella P., Ghezzi P., Faggioni R., Luini W., Van Hinsbergh V., Sozzani S., Bussolino F., Poli V., Ciliberto G., Mantovani A., Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment Immunity 1997 6 3 315 325 (Pubitemid 27148598)
-
(1997)
Immunity
, vol.6
, Issue.3
, pp. 315-325
-
-
Romano, M.1
Sironi, M.2
Toniatti, C.3
Polentarutti, N.4
Fruscella, P.5
Ghezzi, P.6
Faggioni, R.7
Luini, W.8
Van Hinsbergh, V.9
Sozzani, S.10
Bussolino, F.11
Poli, V.12
Ciliberto, G.13
Mantovani, A.14
-
3
-
-
0027398766
-
The soluble interleukin-6 receptor is generated by shedding
-
Mullberg J., Schooltink H., Stoyan T., Gunther M., Graeve L., Buse G., Mackiewicz A., Heinrich P. C., Rose-John S., The soluble interleukin-6 receptor is generated by shedding European Journal of Immunology 1993 23 2 473 480 (Pubitemid 23075080)
-
(1993)
European Journal of Immunology
, vol.23
, Issue.2
, pp. 473-480
-
-
Mullberg, J.1
Schooltink, H.2
Stoyan, T.3
Gunther, M.4
Graeve, L.5
Buse, G.6
Mackiewicz, A.7
Heinrich, P.C.8
Rose-John, S.9
-
4
-
-
0027074343
-
Protein kinase C activity is rate limiting for shedding of the interleukin 6 receptor
-
DOI 10.1016/0006-291X(92)92272-Y
-
Mullberg J., Schooltink H., Stoyan T., Heinrich P. C., Rose-John S., Protein kinase C activity is rate limiting for shedding of the interleukin 6 receptor Biochemical and Biophysical Research Communications 1992 189 2 794 800 (Pubitemid 23032443)
-
(1992)
Biochemical and Biophysical Research Communications
, vol.189
, Issue.2
, pp. 794-800
-
-
Mullberg, J.1
Schooltink, H.2
Stoyan, T.3
Heinrich, P.C.4
Rose-John, S.5
-
5
-
-
0026828552
-
Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor
-
Lust J. A., Donovan K. A., Kline M. P., Greipp P. R., Kyle R. A., Maihle N. J., Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor Cytokine 1992 4 2 96 100
-
(1992)
Cytokine
, vol.4
, Issue.2
, pp. 96-100
-
-
Lust, J.A.1
Donovan, K.A.2
Kline, M.P.3
Greipp, P.R.4
Kyle, R.A.5
Maihle, N.J.6
-
6
-
-
0028087834
-
Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism
-
DOI 10.1002/eji.1830240837
-
Horiuchi S., Koyanagi Y., Zhou Y., Miyamoto H., Tanaka Y., Waki M., Matsumoto A., Yamamoto M., Yamamoto N., Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism European Journal of Immunology 1994 24 8 1945 1948 (Pubitemid 24237574)
-
(1994)
European Journal of Immunology
, vol.24
, Issue.8
, pp. 1945-1948
-
-
Horiuchi, S.1
Koyanagi, Y.2
Zhou, Y.3
Miyamoto, H.4
Tanaka, Y.5
Waki, M.6
Matsumoto, A.7
Yamamoto, M.8
Yamamoto, N.9
-
7
-
-
0036772859
-
Chemotactic agents induce IL-6Ralpha shedding from polymorphonuclear cells: Involvement of a metalloprotease of the TNFalpha converting enzyme (TACE) type
-
Marin V., Montero-Julian F. A., Gres S., Bongrnad P., Farnarier C., Kaplanski G., Chemotactic agents induce IL-6Ralpha shedding from polymorphonuclear cells: involvement of a metalloprotease of the TNFalpha converting enzyme (TACE) type European Journal of Immunology 2002 32 2965 2972
-
(2002)
European Journal of Immunology
, vol.32
, pp. 2965-2972
-
-
Marin, V.1
Montero-Julian, F.A.2
Gres, S.3
Bongrnad, P.4
Farnarier, C.5
Kaplanski, G.6
-
8
-
-
0037829128
-
Serum concentrations of the CXC chemokines interleukin 8 and growth-regulated oncogene- are elevated in patients with systemic sclerosis
-
Furuse S., Fujii H., Kaburagi Y., Fujimoto M., Hasegawa M., Takehara K., Sato S., Serum concentrations of the CXC chemokines interleukin 8 and growth-regulated oncogene- are elevated in patients with systemic sclerosis Journal of Rheumatology 2003 30 7 1524 1528 (Pubitemid 36835450)
-
(2003)
Journal of Rheumatology
, vol.30
, Issue.7
, pp. 1524-1528
-
-
Furuse, S.1
Fujii, H.2
Kaburagi, Y.3
Fujimoto, M.4
Hasegawa, M.5
Takehara, K.6
Sato, S.7
-
9
-
-
0027397988
-
Demonstration of interleukin 8 and autoantibodies to interleukin 8 in the serum of patients with systemic sclerosis and related disorders
-
DOI 10.1001/archderm.129.2.189
-
Reitamo S., Remitz A., Varga J., Ceska M., Effenberger F., Jimenez S., Uitto J., Demonstration of interleukin 8 and autoantibodies to interleukin 8 in the serum of patients with systemic sclerosis and related disorders Archives of Dermatology 1993 129 2 189 193 (Pubitemid 23063871)
-
(1993)
Archives of Dermatology
, vol.129
, Issue.2
, pp. 189-193
-
-
Reitamo, S.1
Remitz, A.2
Varga, J.3
Ceska, M.4
Effenberger, F.5
Jimenez, S.6
Uitto, J.7
-
10
-
-
29144443643
-
Cyclooxygenase- and lipoxygenase-derived eicosanoids in bronchoalveolar lavage fluid from patients with scleroderma lung disease: An imbalance between proinflammatory and antiinflammatory lipid mediators
-
DOI 10.1002/art.21432
-
Kowal-Bielecka O., Kowal K., Distler O., Rojewska J., Bodzenta-Lukaszyk A., Michel B. A., Gay R. E., Gay S., Sierakowski S., Cyclooxygenase- and lipoxygenase-derived eicosanoids in bronchoalveolar lavage fluid from patients with scleroderma lung disease: an imbalance between proinflammatory and antiinflammatory lipid mediators Arthritis and Rheumatism 2005 52 12 3783 3791 (Pubitemid 41798216)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.12
, pp. 3783-3791
-
-
Kowal-Bielecka, O.1
Kowal, K.2
Distler, O.3
Rojewska, J.4
Bodzenta-Lukaszyk, A.5
Michel, B.A.6
Gay, R.E.7
Gay, S.8
Sierakowski, S.9
-
11
-
-
18644385612
-
IL-6 transsignaling: The in vivo consequences
-
DOI 10.1089/jir.2005.25.241
-
Jones S. A., Richards P. J., Scheller J., Rose-John S., IL-6 transsignaling: the in vivo consequences Journal of Interferon and Cytokine Research 2005 25 5 241 253 (Pubitemid 40664421)
-
(2005)
Journal of Interferon and Cytokine Research
, vol.25
, Issue.5
, pp. 241-253
-
-
Jones, S.A.1
Richards, P.J.2
Scheller, J.3
Rose-John, S.4
-
12
-
-
0037213682
-
IL-6: A regulator of the transition from neutrophil to monocyte recruitment during inflammation
-
DOI 10.1016/S1471-4906(02)00013-3, PII S1471490602000133
-
Kaplanski G., Marin V., Montero-Julian F., Mantovani A., Farnarier C., IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation Trends in Immunology 2003 24 1 25 29 (Pubitemid 35462110)
-
(2003)
Trends in Immunology
, vol.24
, Issue.1
, pp. 25-29
-
-
Kaplanski, G.1
Marin, V.2
Montero-Julian, F.3
Mantovani, A.4
Farnarier, C.5
-
13
-
-
32144454167
-
Longitudinal analysis of serum cytokine concentrations in systemic sclerosis: Association of interleukin 12 elevation with spontaneous regression of skin sclerosis
-
Matsushita T., Hasegawa M., Hamaguchi Y., Takehara K., Sato S., Longitudinal analysis of serum cytokine concentrations in systemic sclerosis: association of interleukin 12 elevation with spontaneous regression of skin sclerosis Journal of Rheumatology 2006 33 2 275 284 (Pubitemid 43209303)
-
(2006)
Journal of Rheumatology
, vol.33
, Issue.2
, pp. 275-284
-
-
Matsushita, T.1
Hasegawa, M.2
Hamaguchi, Y.3
Takehara, K.4
Sato, S.5
-
14
-
-
0034856397
-
Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis
-
DOI 10.1016/S0923-1811(01)00128-1, PII S0923181101001281
-
Sato S., Hasegawa M., Takehara K., Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis Journal of Dermatological Science 2001 27 2 140 146 (Pubitemid 32781022)
-
(2001)
Journal of Dermatological Science
, vol.27
, Issue.2
, pp. 140-146
-
-
Sato, S.1
Hasegawa, M.2
Takehara, K.3
-
15
-
-
0026767273
-
Mechanisms of pathogenesis in scleroderma. I. Overproduction of interleukin 6 by fibroblasts cultured from affected skin sites of patients with scleroderma
-
Feghali C. A., Bost K. L., Boulware D. W., Levy L. S., Mechanisms of pathogenesis in scleroderma. I. Overproduction of interleukin 6 by fibroblasts cultured from affected skin sites of patients with scleroderma Journal of Rheumatology 1992 19 8 1207 1211
-
(1992)
Journal of Rheumatology
, vol.19
, Issue.8
, pp. 1207-1211
-
-
Feghali, C.A.1
Bost, K.L.2
Boulware, D.W.3
Levy, L.S.4
-
16
-
-
0031935542
-
Increased production of interleukin 6 and interleukin 8 in scleroderma fibroblasts
-
Kadono T., Kikuchi K., Ihn H., Takehara K., Tamaki K., Increased production of interleukin 6 and interleukin 8 in scleroderma fibroblasts Journal of Rheumatology 1998 25 2 296 301 (Pubitemid 28088258)
-
(1998)
Journal of Rheumatology
, vol.25
, Issue.2
, pp. 296-301
-
-
Kadono, T.1
Kikuchi, K.2
Ihn, H.3
Takehara, K.4
Tamaki, K.5
-
17
-
-
0029913252
-
Peripheral blood mononuclear cells of patients with systemic sclerosis produce increased amounts of interleukin 6, but not transforming growth factor 1
-
Giacomelli R., Cipriani P., Danese C., Pizzuto P., Lattanzio R., Parzanese I., Passacantando A., Perego M. A., Tonietti G., Peripheral blood mononuclear cells of patients with systemic sclerosis produce increased amounts of interleukin 6, but not transforming growth factor 1 Journal of Rheumatology 1996 23 2 294 296 (Pubitemid 126500951)
-
(1996)
Journal of Rheumatology
, vol.23
, Issue.2
, pp. 294-296
-
-
Giacomelli, R.1
Cipriani, P.2
Danese, C.3
Pizzuto, P.4
Lattanzio, R.5
Parzanese, I.6
Passacantando, A.7
Perego, M.A.8
Tonietti, G.9
-
18
-
-
0031911610
-
Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis
-
Hasegawa M., Sato S., Fujimoto M., Ihn H., Kikuchi K., Takehara K., Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis Journal of Rheumatology 1998 25 2 308 313 (Pubitemid 28088260)
-
(1998)
Journal of Rheumatology
, vol.25
, Issue.2
, pp. 308-313
-
-
Hasegawa, M.1
Sato, S.2
Fujimoto, M.3
Ihn, H.4
Kikuchi, K.5
Takehara, K.6
-
19
-
-
3142670517
-
Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis
-
DOI 10.1161/01.RES.0000134644.89917.96
-
Distler O., Distler J. H. W., Scheid A., Acker T., Hirth A., Rethage J., Michel B. A., Gay R. E., Mller-Ladner U., Matucci-Cerinic M., Plate K. H., Gassmann M., Gay S., Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis Circulation Research 2004 95 1 109 116 (Pubitemid 38931842)
-
(2004)
Circulation Research
, vol.95
, Issue.1
, pp. 109-116
-
-
Distler, O.1
Distler, J.H.W.2
Scheid, A.3
Acker, T.4
Hirth, A.5
Rethage, J.6
Michel, B.A.7
Gay, R.E.8
Muller-Ladner, U.9
Matucci-Cerinic, M.10
Plate, K.H.11
Gassmann, M.12
Gay, S.13
-
20
-
-
4143153849
-
Interleukin-6-induced JAK2/STAT3 signaling pathway in endothelial cells is suppressed by hemodynamic flow
-
DOI 10.1152/ajpcell.00532.2003
-
Ni C. W., Hsieh H. J., Chao Y. J., Wang D. L., Interleukin-6-induced JAK2/STAT3 signaling pathway in endothelial cells is suppressed by hemodynamic flow American Journal of PhysiologyCell Physiology 2004 287 3 C771 C780 (Pubitemid 39095864)
-
(2004)
American Journal of Physiology - Cell Physiology
, vol.287
, Issue.3
-
-
Ni, C.-W.1
Hsieh, H.-J.2
Chao, Y.-J.3
Wang, D.L.4
-
21
-
-
77956992383
-
B cell depletion in diffuse progressive systemic sclerosis: Safety, skin score modification and IL-6 modulation in an up to thirty-six months follow-up open-label trial
-
Bosello S., De Santis M., Lama G., Span C., Angelucci C., Tolusso B., Sica G., Ferraccioli G., B cell depletion in diffuse progressive systemic sclerosis: safety, skin score modification and IL-6 modulation in an up to thirty-six months follow-up open-label trial Arthritis Research and Therapy 2010 12 2
-
(2010)
Arthritis Research and Therapy
, vol.12
, Issue.2
-
-
Bosello, S.1
De Santis, M.2
Lama, G.3
Span, C.4
Angelucci, C.5
Tolusso, B.6
Sica, G.7
Ferraccioli, G.8
-
22
-
-
0034960582
-
IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation
-
DOI 10.1016/S1074-7613(01)00151-0
-
Hurst S. M., Wilkinson T. S., McLoughlin R. M., Jones S., Horiuchi S., Yamamoto N., Rose-John S., Fuller G. M., Topley N., Jones S. A., IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation Immunity 2001 14 6 705 714 (Pubitemid 32592418)
-
(2001)
Immunity
, vol.14
, Issue.6
, pp. 705-714
-
-
Hurst, S.M.1
Wilkinson, T.S.2
McLoughlin, R.M.3
Jones, S.4
Horiuchi, S.5
Yamamoto, N.6
Rose-John, S.7
Fuller, G.M.8
Topley, N.9
Jones, S.A.10
-
23
-
-
85047689521
-
Interplay between IFN- and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation
-
DOI 10.1172/JCI200317129
-
McLoughlin R. M., Witowski J., Robson R. L., Wilkinson T. S., Hurst S. M., Williams A. S., Williams J. D., Rose-John S., Jones S. A., Topley N., Interplay between IFN- and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation Journal of Clinical Investigation 2003 112 4 598 607 (Pubitemid 38056344)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.4
, pp. 598-607
-
-
McLoughlin, R.M.1
Witowski, J.2
Robson, R.L.3
Wilkinson, T.S.4
Hurst, S.M.5
Williams, A.S.6
Williams, J.D.7
Rose-John, S.8
Jones, S.A.9
Topley, N.10
-
24
-
-
0026800839
-
The induction by human interleukin-6 of apoptosis in the promonocytic cell line U937 and human neutrophils
-
Afford S. C., Pongracz J., Stockley R. A., Crocker J., Burnett D., The induction by human interleukin-6 of apoptosis in the promonocytic cell line U937 and human neutrophils Journal of Biological Chemistry 1992 267 30 21612 21616
-
(1992)
Journal of Biological Chemistry
, vol.267
, Issue.30
, pp. 21612-21616
-
-
Afford, S.C.1
Pongracz, J.2
Stockley, R.A.3
Crocker, J.4
Burnett, D.5
-
25
-
-
0026795415
-
Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products
-
Colotta F., Re F., Polentarutti N., Sozzani S., Mantovani A., Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products Blood 1992 80 8 2012 2020
-
(1992)
Blood
, vol.80
, Issue.8
, pp. 2012-2020
-
-
Colotta, F.1
Re, F.2
Polentarutti, N.3
Sozzani, S.4
Mantovani, A.5
-
26
-
-
0028788388
-
Interleukin-6 suppression of neutrophil apoptosis is neutrophil concentration dependent
-
Biffl W. L., Moore E. E., Moore F. A., Barnett C. C., Interleukin-6 suppression of neutrophil apoptosis is neutrophil concentration dependent Journal of Leukocyte Biology 1995 58 5 582 584
-
(1995)
Journal of Leukocyte Biology
, vol.58
, Issue.5
, pp. 582-584
-
-
Biffl, W.L.1
Moore, E.E.2
Moore, F.A.3
Barnett, C.C.4
-
27
-
-
0034810738
-
Tissue-specific autoregulation of the stat3 gene and its role in interleukin-6-induced survival signals in t cells
-
DOI 10.1128/MCB.21.19.6615-6625.2001
-
Narimatsu M., Maeda H., Itoh S., Atsumi T., Ohtani T., Nishida K., Itoh M., Kamimura D., Park S. J., Mizuno K., Miyazaki J. I., Hibi M., Ishihara K., Nakajima K., Hirano T., Tissue-specific autoregulation of the stat3 gene and its role in interleukin-6-induced survival signals in t cells Molecular and Cellular Biology 2001 21 19 6615 6625 (Pubitemid 32927428)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.19
, pp. 6615-6625
-
-
Narimatsu, M.1
Maeda, H.2
Itoh, S.3
Atsumi, T.4
Ohtani, T.5
Nishida, K.6
Itoh, M.7
Kamimura, D.8
Park, S.-J.9
Mizuno, K.10
Miyazaki, J.-I.11
Hibi, M.12
Ishihara, K.13
Nakajima, K.14
Hirano, T.15
-
28
-
-
0031570453
-
IL-6 Rescues Resting Mouse T Cells From Apoptosis
-
Teague T. K., Marrack P., Kappler J. W., Vella A. T., IL-6 rescues resting mouse T cells from apoptosis Journal of Immunology 1997 158 12 5791 5796 (Pubitemid 127483985)
-
(1997)
Journal of Immunology
, vol.158
, Issue.12
, pp. 5791-5796
-
-
Teague, T.K.1
Marrack, P.2
Kappler, J.W.3
Vella, A.T.4
-
29
-
-
6344247561
-
Inhibition of T cell apoptosis in the aqueous humor of patients with uveitis by IL-6/soluble IL-6 receptor trans-signaling
-
Curnow S. J., Scheel-Toellner D., Jenkinson W., Raza K., Durrani O. M., Faint J. M., Rauz S., Wloka K., Pilling D., Rose-John S., Buckley C. D., Murray P. I., Salmon M., Inhibition of T cell apoptosis in the aqueous humor of patients with uveitis by IL-6/soluble IL-6 receptor trans-signaling Journal of Immunology 2004 173 8 5290 5297 (Pubitemid 39387813)
-
(2004)
Journal of Immunology
, vol.173
, Issue.8
, pp. 5290-5297
-
-
Curnow, S.J.1
Scheel-Toellner, D.2
Jenkinson, W.3
Raza, K.4
Durrani, O.M.5
Faint, J.M.6
Rauz, S.7
Wloka, K.8
Pilling, D.9
Rose-John, S.10
Buckley, C.D.11
Murray, P.I.12
Salmon, M.13
-
30
-
-
0032213273
-
Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell- specific stat3-deficient mice
-
Takeda K., Kaisho T., Yoshida N., Takeda J., Kishimoto T., Akira S., Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell- specific stat3-deficient mice Journal of Immunology 1998 161 9 4652 4660 (Pubitemid 28492039)
-
(1998)
Journal of Immunology
, vol.161
, Issue.9
, pp. 4652-4660
-
-
Takeda, K.1
Kaisho, T.2
Yoshida, N.3
Takeda, J.4
Kishimoto, T.5
Akira, S.6
-
31
-
-
0027717313
-
In situ expression of cytokines and cellular adhesion molecules in the skin of patients with systemic sclerosis. Their role in early and late disease
-
Koch A. E., Kronfeld-Harrington L. B., Szekanecz Z., Cho M., Haines G. K., Harlow L. A., Strieter R. M., Kunkel S. L., Massa M. C., Barr W. G., Jimenez S. A., In situ expression of cytokines and cellular adhesion molecules in the skin of patients with systemic sclerosis. Their role in early and late disease Pathobiology 1993 61 5-6 239 246 (Pubitemid 24007481)
-
(1993)
Pathobiology
, vol.61
, Issue.5-6
, pp. 239-246
-
-
Koch, A.E.1
Kronfeld-Harrington, L.B.2
Szekanecz, Z.3
Cho, M.4
Haines, G.K.5
Harlow, L.A.6
Strieter, R.M.7
Kunkel, S.L.8
Massa, M.C.9
Barr, W.G.10
Jimenez, S.A.11
-
32
-
-
18344410191
-
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo
-
DOI 10.1038/75068
-
Atreya R., Mudter J., Finotto S., Blockade of interleukin 6 trans signalling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo Nature Medicine 2000 6 583 588 (Pubitemid 30305911)
-
(2000)
Nature Medicine
, vol.6
, Issue.5
, pp. 583-588
-
-
Atreya, R.1
Mudter, J.2
Finotto, S.3
Mullberg, J.4
Jostock, T.5
Wirtz, S.6
Schutz, M.7
Bartsch, B.8
Holtmann, M.9
Becker, C.10
Strand, D.11
Czaja, J.12
Schlaak, J.F.13
Lehr, H.A.14
Autschbach, F.15
Schurmann, G.16
Nishimoto, N.17
Yoshizaki, K.18
Ito, H.19
Kishimoto, T.20
Galle, P.R.21
Rose-John, S.22
Neurath, M.F.23
more..
-
33
-
-
0028580429
-
Interleukin-6 inhibits hepatocyte taurocholate uptake and sodium- potassium-adenosinetriphosphatase activity
-
Green R. M., Whiting J. F., Rosenbluth A. B., Beier D., Gollan J. L., Interleukin-6 inhibits hepatocyte taurocholate uptake and sodium- potassium-adenosinetriphosphatase activity American Journal of Physiology 1994 267 6 G1094 G1100
-
(1994)
American Journal of Physiology
, vol.267
, Issue.6
-
-
Green, R.M.1
Whiting, J.F.2
Rosenbluth, A.B.3
Beier, D.4
Gollan, J.L.5
-
34
-
-
0032410575
-
In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen
-
DOI 10.1073/pnas.95.25.14903
-
Drakesmith H., O'Neil D., Schneider S. C., Binks M., Medd P., Sercarz E., Beverley P., Chain B., In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen Proceedings of the National Academy of Sciences of the United States of America 1998 95 25 14903 14908 (Pubitemid 29003729)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.25
, pp. 14903-14908
-
-
Drakesmith, H.1
O'Neil, D.2
Schneider, S.C.3
Binks, M.4
Medd, P.5
Sercarz, E.6
Beverley, P.7
Chain, B.8
-
35
-
-
0032996618
-
Graft tolerance: A duel of two signals
-
DOI 10.1038/9458
-
Matzinger P., Graft tolerance: a duel of two signals Nature Medicine 1999 5 6 616 617 (Pubitemid 29289419)
-
(1999)
Nature Medicine
, vol.5
, Issue.6
, pp. 616-617
-
-
Matzinger, P.1
-
36
-
-
0037064550
-
The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases
-
Kallen K. J., The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases Biochimica et Biophysica Acta 2002 1592 3 323 343
-
(2002)
Biochimica et Biophysica Acta
, vol.1592
, Issue.3
, pp. 323-343
-
-
Kallen, K.J.1
-
37
-
-
0035164602
-
The soluble interleukin 6 receptor: Mechanisms of production and implications in disease
-
DOI 10.1096/fj.99-1003rev
-
Jones S. A., Horiuchi S., Topley N., Yamamoto N., Fuller G. M., The soluble interleukin 6 receptor: mechanisms of production and implications in disease FASEB Journal 2001 15 1 43 58 (Pubitemid 32061655)
-
(2001)
FASEB Journal
, vol.15
, Issue.1
, pp. 43-58
-
-
Jones, S.A.1
Horiuchi, S.2
Topley, N.3
Yamamoto, N.4
Fuller, G.M.5
-
38
-
-
78149474747
-
Although IL-6 trans-signaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity
-
Lissilaa R., Buatois V., Magistrelli G., Williams A. S., Jones G. W., Herren S., Shang L., Malinge P., Guilhot F., Chatel L., Hatterer E., Jones S. A., Kosco-Vilbois M. H., Ferlin W. G., Although IL-6 trans-signaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity Journal of Immunology 2010 185 9 5512 5521
-
(2010)
Journal of Immunology
, vol.185
, Issue.9
, pp. 5512-5521
-
-
Lissilaa, R.1
Buatois, V.2
Magistrelli, G.3
Williams, A.S.4
Jones, G.W.5
Herren, S.6
Shang, L.7
Malinge, P.8
Guilhot, F.9
Chatel, L.10
Hatterer, E.11
Jones, S.A.12
Kosco-Vilbois, M.H.13
Ferlin, W.G.14
-
39
-
-
0033758304
-
Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95
-
Sgonc R., Gruschwitz M. S., Boeck G., Sepp N., Gruber J., Wick G., Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95 Arthritis and Rheumatism 2000 43 11 2550 2562
-
(2000)
Arthritis and Rheumatism
, vol.43
, Issue.11
, pp. 2550-2562
-
-
Sgonc, R.1
Gruschwitz, M.S.2
Boeck, G.3
Sepp, N.4
Gruber, J.5
Wick, G.6
-
40
-
-
0141676369
-
In vivo analysis of the apoptosis-inducing effect of anti-endothelial cell antibodies in systemic sclerosis by the chorionallantoic membrane assay
-
DOI 10.1002/art.11179
-
Worda M., Sgonc R., Dietrich H., Niederegger H., Sundick R. S., Gershwin M. E., Wick G., In vivo analysis of the apoptosis-inducing effect of anti-endothelial cell antibodies in systemic sclerosis by the chorionallantoic membrane assay Arthritis and Rheumatism 2003 48 9 2605 2614 (Pubitemid 37129437)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.9
, pp. 2605-2614
-
-
Worda, M.1
Sgonc, R.2
Dietrich, H.3
Niederegger, H.4
Sundick, R.S.5
Gershwin, M.E.6
Wick, G.7
-
41
-
-
44649085694
-
Pathogenic autoantibodies in systemic sclerosis
-
DOI 10.1016/j.coi.2007.11.004, PII S0952791507001859, Autoimmunity / Allergy and Hypersenditivity
-
Gabrielli A., Svegliati S., Moroncini G., Avvedimento E. V., Pathogenic autoantibodies in systemic sclerosis Current Opinion in Immunology 2007 19 6 640 645 (Pubitemid 50014683)
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.6
, pp. 640-645
-
-
Gabrielli, A.1
Svegliati, S.2
Moroncini, G.3
Avvedimento, E.V.4
-
42
-
-
0031736547
-
Biology of the scleroderma fibroblast
-
DOI 10.1097/00002281-199811000-00011
-
Strehlow D., Korn J. H., Biology of the scleroderma fibroblast Current Opinion in Rheumatology 1998 10 6 572 578 (Pubitemid 28508752)
-
(1998)
Current Opinion in Rheumatology
, vol.10
, Issue.6
, pp. 572-578
-
-
Strehlow, D.1
Korn, J.H.2
-
43
-
-
0029930901
-
IL-6-soluble IL-6 receptor complex inhibits the proliferation of dermal fibroblasts
-
DOI 10.1016/0192-0561(95)00106-9
-
Mihara M., Moriya Y., Ohsugi Y., IL-6-soluble IL-6 receptor complex inhibits the proliferation of dermal fibroblasts International Journal of Immunopharmacology 1996 18 1 89 94 (Pubitemid 26122640)
-
(1996)
International Journal of Immunopharmacology
, vol.18
, Issue.1
, pp. 89-94
-
-
Mihara, M.1
Moriya, Y.2
Ohsugi, Y.3
-
44
-
-
0025989368
-
Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6
-
Duncan M. R., Berman B., Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6 Journal of Investigative Dermatology 1991 97 4 686 692
-
(1991)
Journal of Investigative Dermatology
, vol.97
, Issue.4
, pp. 686-692
-
-
Duncan, M.R.1
Berman, B.2
-
45
-
-
0345517294
-
Soluble IL-6 receptor induces calcium flux and selectively modulates chemokine expression in human dermal fibroblasts
-
DOI 10.1093/intimm/11.7.1053
-
Sprri B., Mller K. M., Wiesmann U., Bickel M., Soluble IL-6 receptor induces calcium flux and selectively modulates chemokine expression in human dermal fibroblasts International Immunology 1999 11 7 1053 1058 (Pubitemid 29338746)
-
(1999)
International Immunology
, vol.11
, Issue.7
, pp. 1053-1058
-
-
Sporri, B.1
Muller, K.M.2
Wiesmann, U.3
Bickel, M.4
-
46
-
-
0029060421
-
Interleukin-6 (IL-6) induces the proliferation of synovial fibroblastic cells in the presence of soluble IL-6 receptor
-
Mihara M., Moriya Y., Kishimoto T., Ohsugi Y., Interleukin-6 (IL-6) induces the proliferation of synovial fibroblastic cells in the presence of soluble IL-6 receptor British Journal of Rheumatology 1995 34 4 321 325
-
(1995)
British Journal of Rheumatology
, vol.34
, Issue.4
, pp. 321-325
-
-
Mihara, M.1
Moriya, Y.2
Kishimoto, T.3
Ohsugi, Y.4
-
47
-
-
0026806180
-
Effects of interleukin-6 on the metabolism of connective tissue components in rheumatoid synovial fibroblasts
-
Ito A., Itoh Y., Sasaguri Y., Morimatsu M., Mori Y., Effects of interleukin-6 on the metabolism of connective tissue components in rheumatoid synovial fibroblasts Arthritis and Rheumatism 1992 35 10 1197 1201
-
(1992)
Arthritis and Rheumatism
, vol.35
, Issue.10
, pp. 1197-1201
-
-
Ito, A.1
Itoh, Y.2
Sasaguri, Y.3
Morimatsu, M.4
Mori, Y.5
-
48
-
-
0036045003
-
The role of soluble interleukin (IL)-6 receptors in mediating the effects of IL-6 on matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 expression by gingival fibroblasts
-
Irwin C. R., Myrillas T. T., Traynor P., Leadbetter N., Cawston T. E., The role of soluble interleukin (IL)-6 receptors in mediating the effects of IL-6 on matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 expression by gingival fibroblasts Journal of Periodontology 2002 73 7 741 747
-
(2002)
Journal of Periodontology
, vol.73
, Issue.7
, pp. 741-747
-
-
Irwin, C.R.1
Myrillas, T.T.2
Traynor, P.3
Leadbetter, N.4
Cawston, T.E.5
-
49
-
-
0038798085
-
Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis
-
DOI 10.1002/art.11143
-
Nakahara H., Song J., Sugimoto M., Hagihara K., Kishimoto T., Yoshizaki K., Nishimoto N., Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis Arthritis and Rheumatism 2003 48 6 1521 1529 (Pubitemid 36682359)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.6
, pp. 1521-1529
-
-
Nakahara, H.1
Song, J.2
Sugimoto, M.3
Hagihara, K.4
Kishimoto, T.5
Yoshizaki, K.6
Nishimoto, N.7
-
50
-
-
78049421175
-
The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab
-
Shima Y., Kuwahara Y., Murota H., Kitaba S., Kawai M., Hirano T., Arimitsu J., Narazaki M., Hagihara K., Ogata A., Katayama I., Kawase I., Kishimoto T., Tanaka T., The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab Rheumatology 2010 49 12 2408 2412
-
(2010)
Rheumatology
, vol.49
, Issue.12
, pp. 2408-2412
-
-
Shima, Y.1
Kuwahara, Y.2
Murota, H.3
Kitaba, S.4
Kawai, M.5
Hirano, T.6
Arimitsu, J.7
Narazaki, M.8
Hagihara, K.9
Ogata, A.10
Katayama, I.11
Kawase, I.12
Kishimoto, T.13
Tanaka, T.14
-
51
-
-
40349108592
-
The Pathology of Scleroderma Vascular Disease
-
DOI 10.1016/j.rdc.2008.01.001, PII S0889857X08000021
-
Fleming J. N., Schwartz S. M., The pathology of scleroderma vascular disease Rheumatic Disease Clinics of North America 2008 34 1 41 55 (Pubitemid 351337630)
-
(2008)
Rheumatic Disease Clinics of North America
, vol.34
, Issue.1
, pp. 41-55
-
-
Fleming, J.N.1
Schwartz, S.M.2
-
52
-
-
0033621643
-
Endothelial in jury in internal organs of University of California at Davis line 200 (UCD 200) chickens, an animal model for systemic sclerosis (Scleroderma)
-
DOI 10.1006/jaut.1999.0355
-
Nguyen V. A., Sgonc R., Dietrich H., Wick G., Endothelial in jury in internal organs of University of California at Davis line 200 (UCD 200) chickens, an animal model for systemic sclerosis (Scleroderma) Journal of Autoimmunity 2000 14 2 143 149 (Pubitemid 30662574)
-
(2000)
Journal of Autoimmunity
, vol.14
, Issue.2
, pp. 143-149
-
-
Nguyen, V.A.1
Sgonc, R.2
Dietrich, H.3
Wick, G.4
-
53
-
-
0030071159
-
Von Willebrand factor, thrombomodulin, thromboxane, -thromboglobulin and markers of fibrinolysis in primary Raynaud's phenomenon and systemic sclerosis
-
Herrick A. L., Illingworth K., Blann A., Hay C. R. M., Hollis S., Jayson M. I. V., Von Willebrand factor, thrombomodulin, thromboxane, -thromboglobulin and markers of fibrinolysis in primary Raynaud's phenomenon and systemic sclerosis Annals of the Rheumatic Diseases 1996 55 2 122 127 (Pubitemid 26050121)
-
(1996)
Annals of the Rheumatic Diseases
, vol.55
, Issue.2
, pp. 122-127
-
-
Herrick, A.L.1
Illingworth, K.2
Blann, A.3
Hay, C.R.M.4
Hollis, S.5
Jayson, M.I.V.6
-
54
-
-
0028862870
-
Altered levels of soluble adhesion molecules in rheumatoid arthritis, vasculitis and systemic sclerosis
-
Blann A. D., Herrick A., Jayson M. I. V., Altered levels of soluble adhesion molecules in rheumatoid arthritis, vasculitis and systemic sclerosis British Journal of Rheumatology 1995 34 9 814 819
-
(1995)
British Journal of Rheumatology
, vol.34
, Issue.9
, pp. 814-819
-
-
Blann, A.D.1
Herrick, A.2
Jayson, M.I.V.3
-
55
-
-
0028837027
-
Correlation of soluble adhesion molecules in the peripheral blood of scleroderma patients with their in situ expression and with disease activity
-
Gruschwitz M. S., Hornstein O. P., von Den Driesch P., Correlation of soluble adhesion molecules in the peripheral blood of scleroderma patients with their in situ expression and with disease activity Arthritis and Rheumatism 1995 38 2 184 189
-
(1995)
Arthritis and Rheumatism
, vol.38
, Issue.2
, pp. 184-189
-
-
Gruschwitz, M.S.1
Hornstein, O.P.2
Von Den Driesch, P.3
-
56
-
-
78751704435
-
Endothelial activation and apoptosis mediated by neutrophil-dependent interleukin 6 trans-signalling: A novel target for systemic sclerosis?
-
Barnes T. C., Spiller D. G., Anderson M. E., Edwards S. W., Moots R. J., Endothelial activation and apoptosis mediated by neutrophil-dependent interleukin 6 trans-signalling: a novel target for systemic sclerosis? Annals of the Rheumatic Diseases 2011 70 2 366 372
-
(2011)
Annals of the Rheumatic Diseases
, vol.70
, Issue.2
, pp. 366-372
-
-
Barnes, T.C.1
Spiller, D.G.2
Anderson, M.E.3
Edwards, S.W.4
Moots, R.J.5
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