Identification of potential biomarkers for predicting acute dermal irritation by proteomic analysis

Journal of Applied Toxicology

Volumn 31, Issue 8, 2011, Pages 762-772

  Zhang, Qihao ^a   Dai, Taoli ^a   Zhang, Lei ^a   Zhang, Minjing ^a   Xiao, Xue ^a   Hu, Hao ^a   Zou, Ping ^a   Liu, Xia ^a   Xiang, Qi ^a   Su, Zhijian ^a   Huang, Yadong ^a   He, Qing Yu ^a  

^a JINAN UNIVERSITY   (China)

Author keywords

CFL1; HSP27; Irritation; Keratinocytes; SOD1

Indexed keywords

10 UNDECENOIC ACID; 3,3 DITHIODIPROPIONIC ACID; BIOLOGICAL MARKER; COFILIN 1; COPPER; DODECYL SULFATE SODIUM; HEAT SHOCK PROTEIN 27; INTERLEUKIN 1ALPHA; MESSENGER RNA; POTASSIUM HYDROXIDE; PROPIONIC ACID DERIVATIVE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ZINC;

ARTICLE; CHILD; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; SKIN IRRITATION; UPREGULATION;

ACUTE DISEASE; BIOLOGICAL MARKERS; CELLS, CULTURED; COFILIN 1; DOWN-REGULATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HSP27 HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-1ALPHA; IRRITANTS; KERATINOCYTES; PROTEOMICS; REAL-TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SKIN; SKIN DISEASES; SUPEROXIDE DISMUTASE; UP-REGULATION;

ANIMALIA;

EID: 81455159116     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1630     Document Type: Article

References (40)

1. Beissert S, Cavazzana I, Mascia F, Meroni P, Pastore S, Tessari G, Girolomoni G. 2006. Mechanisms of immune-mediated skin diseases: an overview. Clin. Exp. Rheumatol. 24: S1-S6.
2. Borlon C, Godard P, Eskes C, Hartung T, Zuang V, Toussaint O. 2007. The usefulness of toxicogenomics for predicting acute skin irritation on in vitro reconstructed human epidermis. Toxicology 241: 157-166.
3. Borrelli MJ, Bernock LJ, Landry J, Spitz DR, Weber LA, Hickey E, Freeman ML, Corry PM. 2002. Stress protection by a fluorescent Hsp27 chimera that is independent of nuclear translocation or multimeric dissociation. Cell Stress Chaperones 7: 281-296.
4. Boxman ILA, Hensbergen PJ, Van der Schors RC, Bruynzeel DP, Tensen CP, Ponec M. 2002a. Proteomic analysis of skin irritation reveals the induction of HSP27 by sodium lauryl sulphate in human skin. Br. J. Dermatol. 146: 777-785.
5. Boxman ILA, Kempenaar J, de Haas E, Ponec M. 2002b. Induction of HSP27 nuclear immunoreactivity during stress is modulated by vitamin C. Exp. Dermatol. 11: 509-517.
6. Corsini E, Galli CL. 2000. Epidermal cytokines in experimental contact dermatitis. Toxicology 142: 203-211.
7. Crapo JD, Oury T, Rabouille C, Slot JW, Chang LY. 1992. Copper, zinc superoxide-dismutase is primarily a cytosolic protein in human-cells. Proc. Natl Acad. Sci. USA 89: 10405-10409.
8. de Brugerolle de F, Picarles V, Chibout S, Kolopp M, Medina J, Burtin P, Ebelin ME, Osborne S, Mayer FK, Spake A, Rosdy M, De Wever B, Ettlin RA, Cordier A. 1999. Predictivity of an in vitro model for acute and chronic skin irritation (SkinEthic) applied to the testing of topical vehicles. Cell Biol. Toxicol. 15: 121-135.
9. de Jongh CM, Lutter R, Verberk MM, Kezic S. 2007. Differential cytokine expression in skin after single and repeated irritation by sodium lauryl sulphate. Exp. Dermatol. 16: 1032-1040.
10. Dinarello CA. 1998. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int. Rev. Immunol. 16: 457-499.
11. Draize JH, Woodard G, Calvery HO. 1944. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J. Pharmacol. Exp. Ther. 82: 377-390.
12. Eguchi R, Naitou H, Kunimasa K, Ayuzawa R, Fujimori Y, Ohashi N, Kaji K, Ohta T. 2008. Proteomic analysis of hypoxia-induced tube breakdown of an in vitro capillary model composed of HUVECs: Potential role of p38-regulated reduction of HSP27. Proteomics 8: 2897-2906.
13. Fentem JH, Briggs D, Chesne C, Elliott GR, Harbell JW, Heylings JR, Portes P, Roguet R, van de Sandt JJM, Botham PA. 2001. A prevalidation study on in vitro tests for acute skin irritation: results and evaluation by the Management Team. Toxicol. in Vitro 15: 57-93.
14. Fulzele SV, Babu RJ, Ahaghotu E, Singh M. 2007. Estimation of proinflammatory biomarkers of skin irritation by dermal microdialysis following exposure with irritant chemicals. Toxicology 237: 77-88.
15. Ghosh M, Song XY, Mouneimne G, Sidani M, Lawrence DS, Condeelis JS. 2004. Cofilin promotes actin polymerization and defines the direction of cell motility. Science 304: 743-746.
16. Huang CM, Foster KW, DeSilva T, Zhang JF, Shi ZK, Yusuf N, Van Kampen KR, Elmets CA, Tang DCC. 2003. Comparative proteomic profiling of murine skin. J. Invest. Dermatol. 121: 51-64.
17. Inarrea P, Moini H, Han D, Rettori D, Aguilo I, Alava MA, Iturralde M, Cadenas E. 2007. Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu, Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis. Biochem. J. 405: 173-179.
18. Ishiwatari S, Suzuki T, Hitomi T, Yoshino T, Matsukuma S, Tsuji T. 2007. Effects of methyl paraben on skin keratinocytes. J. Appl. Toxicol. 27: 1-9.
19. Jirova D, Basketter D, Liebsch M, Bendova H, Kejlova K, Marriott M, Kandarova H. 2010. Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data. Contact Dermatitis 62: 109-116.
20. Kandarova H, Hayden P, Klausner M, Kubilus J, Kearney P, Sheasgreen J. 2009. In vitro skin irritation testing: improving the sensitivity of the EpiDerm Skin Irritation Test protocol. Altern. Lab. Anim. 37: 671-689.
21. Kidd DA, Johnson M, Clements J. 2007. Development of an in vitro corrosion/irritation prediction assay using the EpiDerm (TM) skin model. Toxicol. in Vitro 21: 1292-1297.
22. Klamt F, Zdanov S, Levine RL, Pariser A, Zhang YQ, Zhang BL, Yu LR, Veenstra TD, Shacter E. 2009. Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin. Nat. Cell Biol. 11: 1241-U1193.
23. Maciver SK, Hussey PJ. 2002. The ADF/cofilin family: actin-remodeling proteins. Genome Biol. 3: review 3007.
24. Marikovsky M, Ziv V, Nevo N, Harris-Cerruti C, Mahler O. 2003. Cu/Zn superoxide dismutase plays important role in immune response. J. Immunol. 170: 2993-3001.
25. McClaren M, Isseroff RR. 1994. Dynamic changes in intracellular-localization and isoforms of the 27-kD stress protein in human keratinocytes. J. Invest. Dermatol. 102: 375-381.
26. Mol MAE, van den Berg RM, Benschop HP. 2008. Proteomic assessment of sulfur mustard-induced protein adducts and other protein modifications in human epidermal keratinocytes. Toxicol. Appl. Pharmacol. 230: 97-108.
27. OECD, 2002. OECD Guideline for Testing of Chemicals No. 404: Acute Dermal Irritation/Corrosion. Organisation for Economic Cooperation and Development, Paris, 1-13.
28. Osborne R, Perkins MA. 1994. An approach for development of alternative test methods based on mechanisms of skin irritation. Food Chem. Toxicol. 32: 133-142.
29. Pivovarova AV, Chebotareva NA, Chernik IS, Gusev NB, Levitsky D I. 2007. Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by forming soluble complexes with denatured actin. Febs J. 274: 5937-5948.
30. Rogers JV, Gunasekar PG, Garrett CM, Kabbur MB, McDougal JN. 2001. Detection of oxidative species and low-molecular-weight DNA in skin following dermal exposure with JP-8 jet fuel. J. Appl. Toxicol. 21: 521-525.
31. Shen T, Zhu QX, Yang S, Wu CH, Zhang HF, Zhou CF, Zhang XJ. 2008. Trichloroethylene induced cutaneous irritation in BALB/c hairless mice: Histopathological changes and oxidative damage. Toxicology 248: 113-120.
32. Sur R, Lyte PA, Southall MD. 2008. Hsp27 regulates pro-inflammatory mediator release in keratinocytes by modulating NF-kappa B signaling. J. Invest. Dermatol. 128: 1116-1122.
33. Tornier C, Amsellem C, de Fraissinette AD, Alepee N. 2010 Assessment of the optimized SkinEthic (TM) reconstructed human epidermis (RHE) 42 bis skin irritation protocol over 39 test substances. Toxicol. in Vitro 24: 245-256.
34. Turrens JF. 2003. Mitochondrial formation of reactive oxygen species. J. Physiol. 552: 335-344.
35. Vigilanza P, Aquilano K, Rotilio G, Ciriolo MR. 2008. Transient cytoskeletal alterations after SOD1 depletion in neuroblastoma cells. Cell. Mol. Life Sci. 65: 991-1004.
36. Welss T, Basketter DA, Schroder KR. 2004. In vitro skin irritation: facts and future. State of the art review of mechanisms and models. Toxicol. in Vitro 18: 231-243.
37. Wong JW, Shi B, Farboud B, McClaren M, Shibamoto T, Cross CE, Isseroff RR. 2000. Ultraviolet B-mediated phosphorylation of the small heat shock protein HSP27 in human keratinocytes. J. Invest. Dermatol. 115: 427-434.
38. Yan XD, Pan LY, Yuan Y, Lang JH, Mao N. 2007. Identification of platinum-resistance associated proteins through proteomic analysis of human ovarian cancer cells and their platinum-resistant sublines. J. Proteome Res. 6: 772-780.
39. Yon JM, Baek IJ, Lee SR, Jin Y, Kim MR, Nahm SS, Kim JS, Ahn B, Lee BJ, Yun YW, Nam SY. 2008. The spatio-temporal expression pattern of cytoplasmic Cu/Zn superoxide dismutase (SOD1) mRNA during mouse embryogenesis. J. Mol. Histol. 39: 95-103.
40. Yusuf N, Nasti TH, Huang CM, Huber BS, Jaleel T, Lin HY, Xu H, Elmets CA. 2009. Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivity. J. Immunol. 182: 675-683.