The usefulness of toxicogenomics for predicting acute skin irritation on in vitro reconstructed human epidermis

Toxicology

Volumn 241, Issue 3, 2007, Pages 157-166

  Borlon, Céline ^a   Godard, Patrice ^a   Eskes, Chantra ^b   Hartung, Thomas ^b   Zuang, Valérie ^b   Toussaint, Olivier ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b JOINT RESEARCH CENTRE   (Italy)

Author keywords

Alternative methods; DNA arrays; Gene expression; Reconstructed epidermis; Skin irritation

Indexed keywords

10 UNDECENOIC ACID; NITROBENZENE; POTASSIUM HYDROXIDE;

ARTICLE; CELL CULTURE; CELL CYCLE; CELL STRUCTURE; CELLULAR STRESS RESPONSE; DISEASE COURSE; DNA MICROARRAY; EPIDERMIS; GENE EXPRESSION; GENOMICS; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN IRRITATION; TOXICOKINETICS; UNINDEXED SEQUENCE;

ANIMAL TESTING ALTERNATIVES; CELL SURVIVAL; DERMATITIS, IRRITANT; DNA; EPIDERMIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; IRRITANTS; KERATINOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREDICTIVE VALUE OF TESTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN IRRITANCY TESTS; TOXICOGENETICS;

ANIMALIA;

EID: 35349018379     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.08.096     Document Type: Article

References (47)

1. Anand S., Chakrabarti E., Kawamura H., Taylor C.R., and Maytin E.V. Ultraviolet light (UVB and UVA) induces the damage-responsive transcription factor CHOP/gadd153 in murine and human epidermis: evidence for a mechanism specific to intact skin. J. Invest. Dermatol. (2005) 323-333
2. Bagley D.M., Gardner J.R., Holland G., Lewis R.W., Stringer D.A., and Walker A.P. Skin irritation: reference chemicals data bank. Toxicol. In Vitro (1996) 1-6
3. Boswell S.A., Ongusaha P.P., Nghiem P., and Lee S.W. The protective role of a small GTPase RhoE against UVB-induced DNA damage in keratinocytes. J. Biol. Chem. (2007) 4850-4858
4. Budihna M., Strojan P., Smid L., Skrk J., Vrhovec I., Zupevc A., Rudolf Z., Zargi M., Krasovec M., Svetic B., Kopitar-Jerala N., and Kos J. Prognostic value of cathepsins B, H, L, D and their endogenous inhibitors stefins A and B in head and neck carcinoma. Biol. Chem. Hoppe Seyler (1996) 385-390
5. Butt A.J., Firth S.M., and Baxter R.C. The IGF axis and programmed cell death. Immunol. Cell Biol. (1999) 256-262
6. Cotovio J., Grandidier M.H., Portes P., Roguet R., and Rubinstenn G. The in vitro skin irritation of chemicals: optimisation of the EPISKIN prediction model within the framework of the ECVAM validation process. Altern. Lab. Anim. (2005) 329-349
7. de Longueville F., Surry D., Meneses-Lorente G., Bertholet V., Talbot V., Evrard S., Chandelier N., Pike A., Worboys P., Rasson J.P., Le Bourdelles B., and Remacle J. Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray. Biochem. Pharmacol. (2002) 137-149
8. 2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase. Exp. Gerontol. (2004) 1379-1389
9. Debacq-Chainiaux F., Borlon C., Pascal T., Royer V., Eliaers F., Ninane N., Carrard G., Friguet B., de Longueville F., Boffe S., Remacle J., and Toussaint O. Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway. J. Cell Sci. (2005) 743-758
10. Donato R. Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. Biochim. Biophys. Acta (1999) 191-231
11. Draize J.H., Woodard G., and Calvery H.O. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J. Pharmacol. Exp. Ther. (1944) 377-390
12. ECETOC, 1995. Skin irritation and corrosion: Reference chemicals data bank. ECETOC Technical report no. 66. In: E.C.f.E.a.T.o. Chemicals (Ed.). Brussels.
13. Eckert R.L., Broome A.M., Ruse M., Robinson N., Ryan D., and Lee K. S100 proteins in the epidermis. J. Invest. Dermatol. (2004) 23-33
14. Eckert R.L., Crish J.F., Efimova T., Dashti S.R., Deucher A., Bone F., Adhikary G., Huang G., Gopalakrishnan R., and Balasubramanian S. Regulation of involucrin gene expression. J. Invest. Dermatol. (2004) 13-22
15. ESAC, 2007. Statement on the validity of in vitro tests for skin irritation.
16. Fentem J.H., Briggs D., Chesne C., Elliott G.R., Harbell J.W., Heylings J.R., Portes P., Roguet R., van de Sandt J.J., and Botham P.A. A prevalidation study on in vitro tests for acute skin irritation. Results and evaluation by the management team. Toxicol. In Vitro (2001) 57-93
17. Fletcher S.T., and Basketter D.A. Proteomic analysis of the response of EpiDerm cultures to sodium lauryl sulphate. Toxicol. In Vitro (2006) 975-985
18. Fregert S. Occupational dermatitis in a 10-year material. Contact Dermatitis (1975) 96-107
19. Fu M., Wang C., Li Z., Sakamaki T., and Pestell R.G. Minireview: cyclin D1: normal and abnormal functions. Endocrinology (2004) 5439-5447
20. Gillet J.P., de Longueville F., and Remacle J. DualChip microarray as a new tool in cancer research. Expert Rev. Mol. Diagn. (2006) 295-306
21. Grimberg A. P53 and IGFBP-3: apoptosis and cancer protection. Mol. Genet. Metab. (2000) 85-98
22. Han E.K., Ng S.C., Arber N., Begemann M., and Weinstein I.B. Roles of cyclin D1 and related genes in growth inhibition, senescence and apoptosis. Apoptosis (1999) 213-219
23. Jansen A.P., Dreckschmidt N.E., Verwiebe E.G., Wheeler D.L., Oberley T.D., and Verma A.K. Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C-alpha, -delta and -epsilon transgenic mice. Int. J. Cancer (2001) 635-643
24. Kandarova H., Liebsch M., Gerner I., Schmidt E., Genschow E., Traue D., and Spielmann H. The EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests-an assessment of the performance of the optimised test. Altern. Lab. Anim. (2005) 351-367
25. Kortlever R.M., Higgins P.J., and Bernards R. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat. Cell Biol. (2006) 877-884
26. Lee K.S., Lee W.S., Suh S.I., Kim S.P., Lee S.R., Ryoo Y.W., and Kim B.C. Melatonin reduces ultraviolet-B induced cell damages and polyamine levels in human skin fibroblasts in culture. Exp. Mol. Med. (2003) 263-268
27. Li E.R., Owens D.M., Djian P., and Watt F.M. Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes. Exp. Dermatol. (2000) 431-438
28. Lok C.N., and Loh T.T. Regulation of transferrin function and expression: review and update. Biol. Signals Recept. (1998) 157-178
29. Malorni W., Testa U., Rainaldi G., Tritarelli E., and Peschle C. Oxidative stress leads to a rapid alteration of transferrin receptor intravesicular trafficking. Exp. Cell Res. (1998) 102-116
30. Manzow S., Richter K.H., Stempka L., Furstenberger G., and Marks F. Evidence against a role of general protein kinase C downregulation in skin tumor promotion. Int. J. Cancer (2000) 503-507
31. Moore J.O., Palep S.R., Saladi R.N., Gao D., Wang Y., Phelps R.G., Lebwohl M.G., and Wei H. Effects of ultraviolet B exposure on the expression of proliferating cell nuclear antigen in murine skin. Photochem. Photobiol. (2004) 587-595
32. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods (1983) 55-63
33. Mu X.C., and Higgins P.J. Differential growth state-dependent regulation of plasminogen activator inhibitor type-1 expression in senescent IMR-90 human diploid fibroblasts. J. Cell Physiol. (1995) 647-657
34. OECD, 2002. Guidelines for the testing of Chemicals No. 404: Acute Dermal irritation/Corrosion, Organisation for Economic Cooperation and Development. Organisation for Economic Cooperation and Development, Paris, France.
35. Pascal T., Debacq-Chainiaux F., Chretien A., Bastin C., Dabee A.F., Bertholet V., Remacle J., and Toussaint O. Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays. FEBS Lett. (2005) 3651-3659
36. Saeed A.I., Sharov V., White J., Li J., Liang W., Bhagabati N., Braisted J., Klapa M., Currier T., Thiagarajan M., Sturn A., Snuffin M., Rezantsev A., Popov D., Ryltsov A., Kostukovich E., Borisovsky I., Liu Z., Vinsavich A., Trush V., and Quackenbush J. TM4: a free, open-source system for microarray data management and analysis. Biotechniques (2003) 374-378
37. Waghray A., Keppler D., Sloane B.F., Schuger L., and Chen Y.Q. Analysis of a truncated form of cathepsin H in human prostate tumor cells. J. Biol. Chem. (2002) 11533-11538
38. Watson P.H., Leygue E.R., and Murphy L.C. Psoriasin (S100A7). Int. J. Biochem. Cell Biol. (1998) 567-571
39. Whittock N.V., and Bower C. Targetting of desmoglein 1 in inherited and acquired skin diseases. Clin. Exp. Dermatol. (2003) 410-415
40. Xu J., and Morris G.F. p53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiation. Mol. Cell Biol. (1999) 12-20
41. York M., Griffiths H.A., Whittle E., and Basketter D.A. Evaluation of a human patch test for the identification and classification of skin irritation potential. Contact Dermatitis (1996) 204-212
42. 2-induced premature senescence of IMR-90 hTERT human fibroblasts. FEBS Lett. (2006) 6455-6463
43. Zeeuwen P.L., Van Vlijmen-Willems I.M., Jansen B.J., Sotiropoulou G., Curfs J.H., Meis J.F., Janssen J.J., Van Ruissen F., and Schalkwijk J. Cystatin M/E expression is restricted to differentiated epidermal keratinocytes and sweat glands: a new skin-specific proteinase inhibitor that is a target for cross-linking by transglutaminase. J. Invest. Dermatol. (2001) 693-701
44. Zeeuwen P.L., van Vlijmen-Willems I.M., Egam H., and Schalkwijk J. Cystatin M/E expression in inflammatory and neoplastic skin disorders. Br. J. Dermatol. (2002) 87-94
45. Zeeuwen P.L., van Vlijmen-Willems I.M., Hendriks W., Merkx G.F., and Schalkwijk J. A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification. Hum. Mol. Genet. (2002) 2867-2875
46. Zuang V., Balls M., Botham P.A., Coquette A., Corsini E., Curren R.D., Elliott G.R., Fentem J.H., Heylings J.R., Liebsch M., Medina J., Roguet R., van de Sandt J.J., Wiemann C., and Worth A.P. Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin irritation. The European Center for the Validation of Alternative Methods Skin Irritation Task Force report 2. Altern. Lab. Anim. (2002) 109-129
47. Zuang, C., Alonso, M.-A., Botham, P.A., Eskes, C., Fentem, J., Liebsch, M., van de Sandt, J.J.M., 2005. Subchapter 3.2. Skin irritation. In: Eskes, C., Zuang, V. (Eds.), Alternative (non-animal) Methods for Cosmetics Testing: Current Status and Future Prospects. ATLA 33 ed., Suppl. 1, pp. 35-46.