Depigmenting action of platycodin D depends on the cAMP/Rho-dependent signalling pathway

Experimental Dermatology

Volumn 20, Issue 12, 2011, Pages 986-991

  Jung, Eunsun ^a   Hwang, Wangtaek ^a   Kim, Seungbeom ^a   Kim, Young Soo ^a   Kim, Yeong Shik ^b   Lee, Jongsung ^a   Park, Deokhoon ^a  

^a Biospectrum Life Science Institute   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

CAMP; Dendrite; GTP binding protein; Melanogenesis; Platycodin D

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EXOENZYME C3; GUANOSINE TRIPHOSPHATASE; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PLATYCODIN; PLATYCODON GRANDIFLORUM EXTRACT; PROTEIN CDC42; RAC PROTEIN; TYROSINASE RELATED PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DENDRITE; DEPIGMENTATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; MELANOGENESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKIN PIGMENTATION;

ADP RIBOSE TRANSFERASES; AMIDES; APOPTOSIS; BOTULINUM TOXINS; CDC42 GTP-BINDING PROTEIN; CELL SHAPE; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DENDRITES; EPIDERMIS; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MELANINS; MELANOCYTES; MEMBRANE GLYCOPROTEINS; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASES; PYRIDINES; RAC GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; SAPONINS; SIGNAL TRANSDUCTION; SKIN PIGMENTATION; TRITERPENES;

EID: 81455158728     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2011.01379.x     Document Type: Article

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