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Volumn 16, Issue 2, 2003, Pages 139-148

The cAMP signaling pathway has opposing effects on Rac and Rho in B16F10 cells: Implications for dendrite formation in melanocytic cells

Author keywords

Cyclic adenosine monophosphate; Melanocyte; Rho proteins

Indexed keywords

BOTULINUM TOXIN; BUCLADESINE; CYCLIC AMP; FORSKOLIN; GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN; RAC PROTEIN; RHO FACTOR;

EID: 0037904506     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0749.2003.00022.x     Document Type: Article
Times cited : (45)

References (59)
  • 1
    • 0018196247 scopus 로고
    • Stimulation of dendritogenesis in the epidermal melanocytes of newborn mice by melanocyte-stimulating hormone
    • Hirobe T. Stimulation of dendritogenesis in the epidermal melanocytes of newborn mice by melanocyte-stimulating hormone. J Cell Sci 1978;33:371-383
    • (1978) J Cell Sci , vol.33 , pp. 371-383
    • Hirobe, T.1
  • 2
    • 0026634711 scopus 로고
    • Melanocyte stimulating hormone induces the differentiation of mouse epidermal melanocytes in serum-free culture
    • Hirobe T. Melanocyte stimulating hormone induces the differentiation of mouse epidermal melanocytes in serum-free culture. J Cell Physiol 1992;152:337-345
    • (1992) J Cell Physiol , vol.152 , pp. 337-345
    • Hirobe, T.1
  • 3
    • 0023630124 scopus 로고
    • Ultraviolet radiation directly induces pigment production by cultured human melanocytes
    • Friedmann PS, Gilchrest BA. Ultraviolet radiation directly induces pigment production by cultured human melanocytes. J Cell Physiol 1987;133:88-94
    • (1987) J Cell Physiol , vol.133 , pp. 88-94
    • Friedmann, P.S.1    Gilchrest, B.A.2
  • 4
    • 0024523764 scopus 로고
    • Regulation of human melanocyte growth, dendricity, and melanization by keratinocyte derived factors
    • Gordon PR, Mansur CP, Gilchrest BA. Regulation of human melanocyte growth, dendricity, and melanization by keratinocyte derived factors. J Invest Dermatol 1989;92:565-572
    • (1989) J Invest Dermatol , vol.92 , pp. 565-572
    • Gordon, P.R.1    Mansur, C.P.2    Gilchrest, B.A.3
  • 5
    • 0026037720 scopus 로고
    • Evidence for nerve growth factor-mediated paracrine effects in human epidermis
    • Yaar M, Grossman K, Eller M, Gilchrest BA. Evidence for nerve growth factor-mediated paracrine effects in human epidermis. J Cell Biol 1991;115:821-828
    • (1991) J Cell Biol , vol.115 , pp. 821-828
    • Yaar, M.1    Grossman, K.2    Eller, M.3    Gilchrest, B.A.4
  • 6
    • 0029582981 scopus 로고
    • Endothelin-1 of keratinocyte origin is a mediator of melanocyte dendricity
    • Hara M, Yaar M, Gilchrest B. Endothelin-1 of keratinocyte origin is a mediator of melanocyte dendricity. J Invest Dermatol 1995;105:744-748
    • (1995) J Invest Dermatol , vol.105 , pp. 744-748
    • Hara, M.1    Yaar, M.2    Gilchrest, B.3
  • 7
    • 0029863304 scopus 로고    scopus 로고
    • Binding of melanotropic hormones to the melanocortin receptor MCIR on human melanocytes stimulates proliferation and melanogenesis
    • Suzuki I, Cone RD, Im S, Nordlund JJ, Abdel-Malek ZA. Binding of melanotropic hormones to the melanocortin receptor MCIR on human melanocytes stimulates proliferation and melanogenesis. Endocrinology 1996;137:1627-1633
    • (1996) Endocrinology , vol.137 , pp. 1627-1633
    • Suzuki, I.1    Cone, R.D.2    Im, S.3    Nordlund, J.J.4    Abdel-Malek, Z.A.5
  • 8
    • 0029670689 scopus 로고    scopus 로고
    • Signalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes
    • Imokawa G, Yada Y, Kimura M. Signalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes. Biochem J 1996;314:305-312
    • (1996) Biochem J , vol.314 , pp. 305-312
    • Imokawa, G.1    Yada, Y.2    Kimura, M.3
  • 9
    • 0031203749 scopus 로고    scopus 로고
    • The role of endothelin-1 in epidermal hyperpigmentation and signaling mechanisms of mitogenesis and melanogenesis
    • Imokawa G, Kobayashi T, Miyagishi M, Higashi K, Yada Y. The role of endothelin-1 in epidermal hyperpigmentation and signaling mechanisms of mitogenesis and melanogenesis. Pigment Cell Res 1997;10:218-228
    • (1997) Pigment Cell Res , vol.10 , pp. 218-228
    • Imokawa, G.1    Kobayashi, T.2    Miyagishi, M.3    Higashi, K.4    Yada, Y.5
  • 10
    • 0032923970 scopus 로고    scopus 로고
    • Nerve growth factor receptor signaling in proliferation of normal adult rat chromaffin cells
    • Powers JF, Shahsavari M, Tsokas P, Tischler AS. Nerve growth factor receptor signaling in proliferation of normal adult rat chromaffin cells. Cell Tissue Res 1999;295:21-32
    • (1999) Cell Tissue Res , vol.295 , pp. 21-32
    • Powers, J.F.1    Shahsavari, M.2    Tsokas, P.3    Tischler, A.S.4
  • 11
    • 0028984317 scopus 로고
    • Edothelin-1 as a new melanogen: Coordinated expression of its gene and the tyrosinase gene in UVB-exposed human epidermis
    • Imokawa G, Miyagishi M, Yada Y. Edothelin-1 as a new melanogen: coordinated expression of its gene and the tyrosinase gene in UVB-exposed human epidermis. J Invest Derm. 1995;105:32-37
    • (1995) J Invest Derm , vol.105 , pp. 32-37
    • Imokawa, G.1    Miyagishi, M.2    Yada, Y.3
  • 12
    • 0024366776 scopus 로고
    • UVB-induced melanogenesis may be mediated through the MSH-receptor system
    • Bologna J, Murray M, Pawelek J. UVB-induced melanogenesis may be mediated through the MSH-receptor system. J Invest Dermatol 1989;92:651-656
    • (1989) J Invest Dermatol , vol.92 , pp. 651-656
    • Bologna, J.1    Murray, M.2    Pawelek, J.3
  • 13
    • 0025758173 scopus 로고
    • Structural functional relationship between internal and external MSH receptors: Modulation of expression in Cloudman melanoma cells by UVB radiation
    • Chakraborty AK, Orlow SJ, Bolognia JL, Pawelek JM. Structural functional relationship between internal and external MSH receptors: modulation of expression in Cloudman melanoma cells by UVB radiation. J Cell Physiol 1991;47:1-6
    • (1991) J Cell Physiol , vol.47 , pp. 1-6
    • Chakraborty, A.K.1    Orlow, S.J.2    Bolognia, J.L.3    Pawelek, J.M.4
  • 14
    • 0001466640 scopus 로고    scopus 로고
    • Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: Regulation by ultraviolet B
    • Chakraborty AK, Funasaka Y, Slominski A, Ermak G, Hwang J, Pawelek JM, Ichihashi M. Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B. Biochim Biophys Acta 1996;1313:130-138
    • (1996) Biochim Biophys Acta , vol.1313 , pp. 130-138
    • Chakraborty, A.K.1    Funasaka, Y.2    Slominski, A.3    Ermak, G.4    Hwang, J.5    Pawelek, J.M.6    Ichihashi, M.7
  • 16
    • 0026800892 scopus 로고
    • The cloning of a family of genes that encode the melanocortin receptors
    • Mountjoy KG, Robbins LS, Mortrud MT, Cone RD. The cloning of a family of genes that encode the melanocortin receptors. Science 1992;257:1248-1251
    • (1992) Science , vol.257 , pp. 1248-1251
    • Mountjoy, K.G.1    Robbins, L.S.2    Mortrud, M.T.3    Cone, R.D.4
  • 19
    • 0031696158 scopus 로고    scopus 로고
    • Induction of exocytosis from permeabilized mast cells by the guanosine triphosphatases Rac and Cdc42
    • Brown AM, O'Sullivan AJ, Gomperts BD. Induction of exocytosis from permeabilized mast cells by the guanosine triphosphatases Rac and Cdc42. Mol Biol Cell 1998;9:1053-1063
    • (1998) Mol Biol Cell , vol.9 , pp. 1053-1063
    • Brown, A.M.1    O'Sullivan, A.J.2    Gomperts, B.D.3
  • 20
    • 0034660180 scopus 로고    scopus 로고
    • Cdc42 stimulates neurite outgrowth and formation of growth cone filopodia and lamellipodia
    • Brown MD, Cornejo BJ, Kuhn TB, Bamburg JR. Cdc42 stimulates neurite outgrowth and formation of growth cone filopodia and lamellipodia. J Neurobiol 2000;43:352-364
    • (2000) J Neurobiol , vol.43 , pp. 352-364
    • Brown, M.D.1    Cornejo, B.J.2    Kuhn, T.B.3    Bamburg, J.R.4
  • 21
    • 0032479425 scopus 로고    scopus 로고
    • Identification of a potential effector pathway for the trimeric Go protein associated with secretory granules, Go stimulates a granulebound phosphatidylinositol 4-kinase by activation RhoA in chromaffin cells
    • Gasman S, Chasserot-Golaz S, Hubert P, Aunis D, Bader MF. Identification of a potential effector pathway for the trimeric Go protein associated with secretory granules, Go stimulates a granulebound phosphatidylinositol 4-kinase by activation RhoA in chromaffin cells. J Biol Chem 1998;273:16913-16920
    • (1998) J Biol Chem , vol.273 , pp. 16913-16920
    • Gasman, S.1    Chasserot-Golaz, S.2    Hubert, P.3    Aunis, D.4    Bader, M.F.5
  • 22
    • 0035836791 scopus 로고    scopus 로고
    • Rho signals to cell growth and apoptosis
    • Aznar S, Lacal JC. Rho signals to cell growth and apoptosis. Cancer Lett 2001;165:1-10
    • (2001) Cancer Lett , vol.165 , pp. 1-10
    • Aznar, S.1    Lacal, J.C.2
  • 23
    • 0033973134 scopus 로고    scopus 로고
    • Selective alterations in biosynthetic and endocytic protein traffic in Madin-Darby canine kidney epithelial cells expressing mutants of the small GTPase Rac1
    • Jou TS, Leung SM, Fung LM, Ruiz WG, Nelson WJ, Apodaca G. Selective alterations in biosynthetic and endocytic protein traffic in Madin-Darby canine kidney epithelial cells expressing mutants of the small GTPase Rac1. Mol Biol Cell 2000;11:287-304
    • (2000) Mol Biol Cell , vol.11 , pp. 287-304
    • Jou, T.S.1    Leung, S.M.2    Fung, L.M.3    Ruiz, W.G.4    Nelson, W.J.5    Apodaca, G.6
  • 25
    • 0034997092 scopus 로고    scopus 로고
    • Rho proteins: Linking signaling with membrane trafficking
    • Ridley AJ. Rho proteins: linking signaling with membrane trafficking. Traffic 2001;2:303-310
    • (2001) Traffic , vol.2 , pp. 303-310
    • Ridley, A.J.1
  • 26
    • 0026778133 scopus 로고
    • The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • Ridley AJ, Hall A. The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992;70:389-399
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 27
    • 0028321785 scopus 로고
    • Signal transduction pathways regulating Rhomedicated stress fiber formation: Requirement for a tyrosine kinase
    • Ridley AJ, Hall A. Signal transduction pathways regulating Rhomedicated stress fiber formation: requirement for a tyrosine kinase. EMBO J 1994;13:2600-2610
    • (1994) EMBO J , vol.13 , pp. 2600-2610
    • Ridley, A.J.1    Hall, A.2
  • 28
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 1992;70:401-410
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 29
    • 0028986034 scopus 로고
    • The Ras-related protein Cde42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
    • Kozma R, Ahmed S, Best A, Lim L. The Ras-related protein Cde42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts. Mol Cell Biol 1995;15:1942-1952
    • (1995) Mol Cell Biol , vol.15 , pp. 1942-1952
    • Kozma, R.1    Ahmed, S.2    Best, A.3    Lim, L.4
  • 30
    • 0028258943 scopus 로고
    • Rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-aceta (TPA)-induced membrane ruffling in KB cells
    • Nishiyama T, Sasak T, Takaishi K, Kato M, Yaku H, Araki K, Matsuura Y, Takai Y. Rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-aceta (TPA)-induced membrane ruffling in KB cells. Mol Cell Biol 1994;14:2447-2456
    • (1994) Mol Cell Biol , vol.14 , pp. 2447-2456
    • Nishiyama, T.1    Sasak, T.2    Takaishi, K.3    Kato, M.4    Yaku, H.5    Araki, K.6    Matsuura, Y.7    Takai, Y.8
  • 33
    • 0024584734 scopus 로고
    • The Rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3
    • Aktories K, Braun U, Rosener S, Just I, Hall A. The Rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3. Biochem Biophys Res Commun 1989;158:209-213
    • (1989) Biochem Biophys Res Commun , vol.158 , pp. 209-213
    • Aktories, K.1    Braun, U.2    Rosener, S.3    Just, I.4    Hall, A.5
  • 34
    • 0030802038 scopus 로고    scopus 로고
    • Rho proteins: Targets for bacterial toxins
    • Aktories K. Rho proteins: targets for bacterial toxins. Trends Microbiol 1997;5:282-288
    • (1997) Trends Microbiol , vol.5 , pp. 282-288
    • Aktories, K.1
  • 35
    • 0030658939 scopus 로고    scopus 로고
    • The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho
    • Van Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho. J Cell Biol 1997;139:797-807
    • (1997) J Cell Biol , vol.139 , pp. 797-807
    • Van Leeuwen, F.N.1    Kain, H.E.2    Kammen, R.A.3    Michiels, F.4    Kranenburg, O.W.5    Collard, J.G.6
  • 36
    • 0033615966 scopus 로고    scopus 로고
    • Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
    • Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol 1999;147:1009-1021
    • (1999) J Cell Biol , vol.147 , pp. 1009-1021
    • Sander, E.E.1    Ten Klooster, J.P.2    Van Delft, S.3    Van der Kammen, R.A.4    Collard, J.G.5
  • 37
    • 0033584865 scopus 로고    scopus 로고
    • Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42
    • Reid T, Bathoorn A, Ahmadian MF, Collard JG. Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42. J Biol Chem 1999;274:33587-33593
    • (1999) J Biol Chem , vol.274 , pp. 33587-33593
    • Reid, T.1    Bathoorn, A.2    Ahmadian, M.F.3    Collard, J.G.4
  • 38
    • 0031596340 scopus 로고    scopus 로고
    • Rac1 mediates dendrite formation in response to melanocyte stimulating hormone and ultraviolet light in a murine melanoma model
    • Scott GA, Cassidy L. Rac1 mediates dendrite formation in response to melanocyte stimulating hormone and ultraviolet light in a murine melanoma model. J Invest Dermatol 1998;111:243-250
    • (1998) J Invest Dermatol , vol.111 , pp. 243-250
    • Scott, G.A.1    Cassidy, L.2
  • 40
    • 0022578454 scopus 로고
    • In vitro assay demonstrates similar invasion profiles for B16F1 and B16F10 murine melanoma cells
    • Gehlsen KR, Hendrix MJ. In vitro assay demonstrates similar invasion profiles for B16F1 and B16F10 murine melanoma cells. Cancer Lett 1986;30:207-212
    • (1986) Cancer Lett , vol.30 , pp. 207-212
    • Gehlsen, K.R.1    Hendrix, M.J.2
  • 41
    • 0020325969 scopus 로고
    • (half-Cys4, half-Cys 10) alpha melanocyte stimulating hormone: A cyclic alpha melanotropic exhibiting superagonist biological activity
    • Sawyer TK, Hruby VJ, Darman PS, Hadley ME. (half-Cys4, half-Cys 10) alpha melanocyte stimulating hormone: a cyclic alpha melanotropic exhibiting superagonist biological activity. Proc Natl Acad Sci USA 1982;79:1751-1755
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 1751-1755
    • Sawyer, T.K.1    Hruby, V.J.2    Darman, P.S.3    Hadley, M.E.4
  • 42
    • 0029889591 scopus 로고    scopus 로고
    • Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain
    • Reid T, Furuyashiki T, Ishizaki T, Watanabe G, Watanabe N, Fujisawa K, Morii N, Madaule P, Narumiya S. Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. J Biol Chem 1996;271:13556-13560
    • (1996) J Biol Chem , vol.271 , pp. 13556-13560
    • Reid, T.1    Furuyashiki, T.2    Ishizaki, T.3    Watanabe, G.4    Watanabe, N.5    Fujisawa, K.6    Morii, N.7    Madaule, P.8    Narumiya, S.9
  • 43
    • 0032583205 scopus 로고    scopus 로고
    • Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
    • Sander EE, van Delft S, ten Klooster JP, Reid T, van der Kammen RA, Michiels F, Collard JG. Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase. J Cell Biol 1998;143:1385-1398
    • (1998) J Cell Biol , vol.143 , pp. 1385-1398
    • Sander, E.E.1    Van Delft, S.2    Ten Klooster, J.P.3    Reid, T.4    Van der Kammen, R.A.5    Michiels, F.6    Collard, J.G.7
  • 44
    • 0026719006 scopus 로고
    • α-melanocyte-stimulating hormone stimulates protein kinase C activity in murine B16 melanoma
    • Buffey J, Thody AJ, Blechen SS, MacNeil S. α-melanocyte-stimulating hormone stimulates protein kinase C activity in murine B16 melanoma. J Endocrin 1992;133:333-340
    • (1992) J Endocrin , vol.133 , pp. 333-340
    • Buffey, J.1    Thody, A.J.2    Blechen, S.S.3    MacNeil, S.4
  • 45
    • 0036538658 scopus 로고    scopus 로고
    • Filopodia are a conduit for melanosome transfer
    • Scott G, Leopardi S, Printup S, Madden B. Filopodia are a conduit for melanosome transfer. J Cell Sci 2002;115:1441-1451
    • (2002) J Cell Sci , vol.115 , pp. 1441-1451
    • Scott, G.1    Leopardi, S.2    Printup, S.3    Madden, B.4
  • 46
    • 0025073547 scopus 로고
    • Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins
    • Fukumoto Y, Kaibuchi K, Hori Y, Fujioka H, Araki S, Ueda T, Kikuchi A, Takai Y. Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins. Oncogene 1990;5:1321-1328
    • (1990) Oncogene , vol.5 , pp. 1321-1328
    • Fukumoto, Y.1    Kaibuchi, K.2    Hori, Y.3    Fujioka, H.4    Araki, S.5    Ueda, T.6    Kikuchi, A.7    Takai, Y.8
  • 47
    • 0025965647 scopus 로고
    • Regulation of binding of rhoB p20 to membranes by its specific regulatory protein, GDP dissociation inhibitor
    • Isomura M, Kikuchi A, Ohga N, Takai Y. Regulation of binding of rhoB p20 to membranes by its specific regulatory protein, GDP dissociation inhibitor. Oncogene 1991;6:119-124
    • (1991) Oncogene , vol.6 , pp. 119-124
    • Isomura, M.1    Kikuchi, A.2    Ohga, N.3    Takai, Y.4
  • 48
    • 0034707597 scopus 로고    scopus 로고
    • RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism
    • O'Connor KL, Nguyen BK, Mercurio AM. RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism. J Cell Biol 2000;148:253-258
    • (2000) J Cell Biol , vol.148 , pp. 253-258
    • O'Connor, K.L.1    Nguyen, B.K.2    Mercurio, A.M.3
  • 49
    • 0035930585 scopus 로고    scopus 로고
    • Protein kinase A regulates Rac and is required for the growth factor-stimulated migration of carcinoma cells
    • O'Connor KL, Mercurio AM. Protein kinase A regulates Rac and is required for the growth factor-stimulated migration of carcinoma cells. J Biol Chem 2001;276:47895-47900
    • (2001) J Biol Chem , vol.276 , pp. 47895-47900
    • O'Connor, K.L.1    Mercurio, A.M.2
  • 50
    • 0034602561 scopus 로고    scopus 로고
    • Hepatoma cell migration through a mesothelial cell monolayer is inhibited by cyclic AMP-elevating agents via a Rho-dependent pathway
    • Mukai M, Nakamura H, Tatsuta M, Iwasaki T, Togawa A, Imamura F, Akedo H. Hepatoma cell migration through a mesothelial cell monolayer is inhibited by cyclic AMP-elevating agents via a Rho-dependent pathway. FEBS Lett 2000;484:69-73
    • (2000) FEBS Lett , vol.484 , pp. 69-73
    • Mukai, M.1    Nakamura, H.2    Tatsuta, M.3    Iwasaki, T.4    Togawa, A.5    Imamura, F.6    Akedo, H.7
  • 51
    • 0032575667 scopus 로고    scopus 로고
    • cAMP-induced morphological changes are counteracted by the activated RhoA smallGTPase and the Rho Kinase ROKα
    • Dong J-M, Leung T, Manser E, Lim L. cAMP-induced morphological changes are counteracted by the activated RhoA smallGTPase and the Rho Kinase ROKα. J Biol Chem 1998;273:22554-22562
    • (1998) J Biol Chem , vol.273 , pp. 22554-22562
    • Dong, J.-M.1    Leung, T.2    Manser, E.3    Lim, L.4
  • 52
    • 0030813029 scopus 로고    scopus 로고
    • Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants
    • Laudanna C, Campbell JJ, Butcher EC. Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants. J Biol Chem 1997;272:24141-24144
    • (1997) J Biol Chem , vol.272 , pp. 24141-24144
    • Laudanna, C.1    Campbell, J.J.2    Butcher, E.C.3
  • 53
    • 0034660145 scopus 로고    scopus 로고
    • Cyclic AMP blocks bacterial lipopolysaccharide-induced myosin light chain phosphorylation in endothelial cells through inhibition of Rho/Rho kinase signaling
    • Essler M, Staddon JM, Weber PC, Aepfelbacher M. Cyclic AMP blocks bacterial lipopolysaccharide-induced myosin light chain phosphorylation in endothelial cells through inhibition of Rho/Rho kinase signaling. J Immuno 2000;164:6543-6549
    • (2000) J Immuno , vol.164 , pp. 6543-6549
    • Essler, M.1    Staddon, J.M.2    Weber, P.C.3    Aepfelbacher, M.4
  • 54
    • 0034658674 scopus 로고    scopus 로고
    • Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition
    • Zondag GC, Evers EE, ten Klooster JP, Janssen L, van der Kammen RA, Collard JG. Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition. J Cell Biol 2000;149:775-782
    • (2000) J Cell Biol , vol.149 , pp. 775-782
    • Zondag, G.C.1    Evers, E.E.2    Ten Klooster, J.P.3    Janssen, L.4    Van der Kammen, R.A.5    Collard, J.G.6
  • 55
    • 0030040750 scopus 로고    scopus 로고
    • Protein kinase A phosphorylation of RhoQ mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
    • Lang P, Gesbert F, Delespine-Carmagnat M, Stancou R, Pouchelet M, Bertoglio J. Protein kinase A phosphorylation of RhoQ mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO J 1996;15:510-519
    • (1996) EMBO J , vol.15 , pp. 510-519
    • Lang, P.1    Gesbert, F.2    Delespine-Carmagnat, M.3    Stancou, R.4    Pouchelet, M.5    Bertoglio, J.6
  • 56
    • 0037081858 scopus 로고    scopus 로고
    • Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes
    • Forget MA, Desrosiers RR, Gingras D, Beliveau R. Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes. Biochem J 2002;361:243-254
    • (2002) Biochem J , vol.361 , pp. 243-254
    • Forget, M.A.1    Desrosiers, R.R.2    Gingras, D.3    Beliveau, R.4
  • 57
    • 0001678613 scopus 로고    scopus 로고
    • Phosphoinositide-dependent activation of RhoA involves partial opening of the RhoA/Rho-GDI complex
    • Faure J, Vignais PV, Dagher MC. Phosphoinositide-dependent activation of RhoA involves partial opening of the RhoA/Rho-GDI complex. Eur J Biochem 1999;262:879-889
    • (1999) Eur J Biochem , vol.262 , pp. 879-889
    • Faure, J.1    Vignais, P.V.2    Dagher, M.C.3
  • 58
    • 0031027205 scopus 로고    scopus 로고
    • Rho family GTPases and neuronal growth cone remodelling: Relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
    • Kozma R, Sarner S, Ahmed S, Lim L. Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid. Mol Cell Biol 1997;17:1201-1211
    • (1997) Mol Cell Biol , vol.17 , pp. 1201-1211
    • Kozma, R.1    Sarner, S.2    Ahmed, S.3    Lim, L.4
  • 59
    • 0030982564 scopus 로고    scopus 로고
    • Regulation of dendritic growth and remodeling by rho, rac, and cdc42
    • Threadgill R, Bobb K, Ghosh A. Regulation of dendritic growth and remodeling by rho, rac, and cdc42. Neuron 1997;19:625-634
    • (1997) Neuron , vol.19 , pp. 625-634
    • Threadgill, R.1    Bobb, K.2    Ghosh, A.3


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