Contribution of the glycidic moieties to the haemolytic and adjuvant activity of platycodigenin-type saponins from the root of Platycodon grandiflorum

Vaccine

Volumn 26, Issue 27-28, 2008, Pages 3452-3460

  Xie, Yong ^a,b   Ye, Yi Ping ^c   Sun, Hong Xiang ^a   Li, Duo ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Adjuvanticity; Haemolysis; Platycodigenin type saponins; Platycodon grandiflorum; Structure activity

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN G2B; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; OVALBUMIN; PLATYCODIN; PLATYCODIN D3; PLATYCOSIDE E; SAPONIN DERIVATIVE; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; FEMALE; GENE SEQUENCE; HEMOLYSIS; HUMORAL IMMUNITY; MOUSE; NONHUMAN; PLATYCODON; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; STRUCTURE ACTIVITY RELATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; EPOXY COMPOUNDS; FEMALE; GENE EXPRESSION PROFILING; HEMOLYSIS; IMMUNOGLOBULIN G; LYMPHOCYTES; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; OVALBUMIN; PLANT ROOTS; PLATYCODON; PROPIONIC ACIDS; SAPONINS; SPLEEN;

EID: 44749094127     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.04.023     Document Type: Article

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