PACAP interactions in the mouse brain: Implications for behavioral and other disorders

Gene

Volumn 491, Issue 2, 2012, Pages 224-231

  Acquaah Mensah, George K ^a   Taylor, Ronald C ^b   Bhave, Sanjiv V ^c  

^a MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Adenylate cyclase; Gsk3b; Network inference; PACAP; PI 3 kinase; Sgk3

Indexed keywords

ADCY7 PROTEIN; ADENYLATE CYCLASE; ADENYLATE KINASE; GLYCOGEN SYNTHASE KINASE 3BETA; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; SERUM GLUCOCORTICOID REGULATED KINASE 3; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BEHAVIOR; BEHAVIOR DISORDER; BIPOLAR DISORDER; COMPUTER ANALYSIS; GENE CLUSTER; GENE EXPRESSION; GENE REGULATORY NETWORK; MAJOR DEPRESSION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION;

ADENYLATE CYCLASE; ALGORITHMS; ANIMALS; BRAIN; GENE REGULATORY NETWORKS; MENTAL DISORDERS; MICE; MICROARRAY ANALYSIS; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; PROTEIN INTERACTION MAPS; SIGNAL TRANSDUCTION;

EID: 81455158394     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2011.09.017     Document Type: Article

References (50)

1. Agam G., Bersudsky Y., Berry G.T., Moechars D., Lavi-Avnon Y., Belmaker R.H. Knockout mice in understanding the mechanism of action of lithium. Biochem. Soc. Trans. 2009, 37:1121-1125.
2. Armstrong B.D., et al. Impaired nerve regeneration and enhanced neuroinflammatory response in mice lacking pituitary adenylyl cyclase activating peptide. Neuroscience 2008, 151:63-73.
3. Bada M., Hunter L. Enrichment of OBO ontologies. J. Biomed. Inform. 2007, 40:300-315.
4. Bader G.D., Hogue C.W. An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinforma. 2003, 4:2.
5. Bhave S.V., et al. The PhenoGen informatics website: tools for analyses of complex traits. BMC Genet. 2007, 8:59.
6. Brandish P.E., et al. Regulation of gene expression by lithium and depletion of inositol in slices of adult rat cortex. Neuron 2005, 45:861-872.
7. Chong Z.Z., Li F., Maiese K. Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury. Histol. Histopathol. 2005, 20:299-315.
8. Costantini C., Scrable H., Puglielli L. An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation. EMBO J. 2006, 25:1997-2006.
9. Cover T.M., Thomas J.A. Elements of Information Theory 2006, Wiley-Interscience.
10. Cummings K.J., Pendlebury J.D., Sherwood N.M., Wilson R.J. Sudden neonatal death in PACAP-deficient mice is associated with reduced respiratory chemoresponse and susceptibility to apnoea. J. Physiol. 2004, 555:15-26.
11. Dai F., et al. Human serum and glucocorticoid-inducible kinase-like kinase (SGKL) phosphorylates glycogen syntheses kinase 3 beta (GSK-3beta) at serine-9 through direct interaction. Biochem. Biophys. Res. Commun. 2002, 293:1191-1196.
12. Dejda A., Sokolowska P., Nowak J.Z. Neuroprotective potential of three neuropeptides PACAP, VIP and PHI. Pharmacol. Rep. 2005, 57:307-320.
13. Deng M., Mehta S., Sun F., Chen T. Inferring domain-domain interactions from protein-protein interactions. Genome Res. 2002, 12:1540-1548.
14. Dong W., Albers J.J., Vuletic S. Phospholipid transfer protein reduces phosphorylation of tau in human neuronal cells. J. Neurosci. Res. 2009, 87:3176-3185.
15. Fatemi S.H., Folsom T.D., Reutiman T.J., Vazquez G. Phosphodiesterase signaling system is disrupted in the cerebella of subjects with schizophrenia, bipolar disorder, and major depression. Schizophr. Res. 2010, 119:266-267.
16. Ferrero A., Cereseto M., Sifonios L. The relationship between the Wnt signaling and the psychiatric diseases. Vertex 2006, 17:165-171.
17. Gout I., et al. Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein. EMBO J. 2000, 19:4015-4025.
18. Hashimoto H., Shintani N., Baba A. New insights into the central PACAPergic system from the phenotypes in PACAP- and PACAP receptor-knockout mice. Ann. N. Y. Acad. Sci. 2006, 1070:75-89.
19. Hashimoto R., et al. Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia. Mol. Psychiatry. 2007, 12:1026-1032.
20. Hashimoto H., et al. Depression-like behavior in the forced swimming test in PACAP-deficient mice: amelioration by the atypical antipsychotic risperidone. J. Neurochem. 2009, 110:595-602.
21. Hashimoto R., et al. Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder. Neurosci. Lett. 2010, 468:300-302.
22. Hines L.M., et al. World Health Organization/International Society for Biomedical Research on Alcoholism Study on State and Trait Markers of Alcohol Use and Dependence Investigators, a sex-specific role of type VII adenylyl cyclase in depression. J. Neurosci. 2006, 26:12609-12619.
23. Jiang L.I., Collins J., Davis R., Fraser I.D., Sternweis P.C. Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII. J. Biol. Chem. 2008, 283:23429-23439.
24. Jones A.R., Overly C.C., Sunkin S.M. The Allen Brain Atlas: 5years and beyond. Nat. Rev. Neurosci. 2009, 10:821-828.
25. Jope R.S. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends Pharmacol. Sci. 2003, 24:441-443.
26. King T.D., Song L., Jope R.S. AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3. Biochem. Pharmacol. 2006, 71:1637-1647.
27. King J.S., et al. The mood stabiliser lithium suppresses PIP3 signalling in Dictyostelium and human cells. Dis. Model. Mech. 2009, 2:306-312.
28. Klein P.S., Melton D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:8455-8459.
29. Kleppisch T., Feil R. cGMP signalling in the mammalian brain: role in synaptic plasticity and behaviour. Handb. Exp. Pharmacol. 2009, 191:549-579.
30. Leach S.M., et al. Biomedical discovery acceleration, with applications to craniofacial development. PLoS Comput. Biol. 2009, 5:e1000215.
31. Lee E., Salic A., Kirschner M.W. Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon. J. Cell Biol. 2001, 154:983-993.
32. Macdonald D.S., et al. Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src. J. Neurosci. 2005, 25:11374-11384.
33. Mangan S., Alon U. Structure and function of the feed-forward loop network motif. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:11980.
34. Margolin A.A., et al. ARACNE: an algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context. BMC Bioinforma. 2006, 7(Suppl. 1):S7.
35. Onoue S., Endo K., Ohshima K., Yajima T., Kashimoto K. The neuropeptide PACAP attenuates beta-amyloid (1-42)-induced toxicity in PC12 cells. Peptides 2002, 23:1471-1478.
36. Opazo P., Watabe A.M., Grant S.G., O'Dell T.J. Phosphatidylinositol 3-kinase regulates the induction of long-term potentiation through extracellular signal-related kinase-independent mechanisms. J. Neurosci. 2003, 23:3679-3688.
37. Pelligrino D.A., Wang Q. Cyclic nucleotide crosstalk and the regulation of cerebral vasodilation. Prog. Neurobiol. 1998, 56:1-18.
38. Ressler K.J., et al. Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature 2011, 470:492-493. 497.
39. Shannon P., et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003, 13:2498-2504.
40. Sheline Y.I., Wang P.W., Gado M.H., Csernansky J.G., Vannier M.W. Hippocampal atrophy in recurrent major depression. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:3908-3913.
41. Sherwood N.M., Krueckl S.L., McRory J.E. The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily. Endocr. Rev. 2000, 21:619-670.
42. Shintani N., et al. Defects in reproductive functions in PACAP-deficient female mice. Regul. Pept. 2002, 109:45-48.
43. Tanaka K., Kunishige-Yamamoto A., Hashimoto H., Shintani N., Hayata A., Baba A. Increased ethanol preference and serotonin 1A receptor-dependent attenuation of ethanol-induced hypothermia in PACAP-deficient mice. Biochem. Biophys. Res. Commun. 2010, 391:773-777.
44. Tessier M., Woodgett J.R. Serum and glucocorticoid-regulated protein kinases: variations on a theme. J. Cell. Biochem. 2006, 98:1391-1407.
45. Tsai S.J., Liou Y.J., Hong C.J., Yu Y.W., Chen T.J. Glycogen synthase kinase-3beta gene is associated with antidepressant treatment response in Chinese major depressive disorder. Pharmacogenomics J. 2008, 8:384-390.
46. Vadigepalli R., Chakravarthula P., Zak D.E., Schwaber J.S., Gonye G.E. PAINT: a promoter analysis and interaction network generation tool for gene regulatory network identification. OMICS. 2003, 7:235-252.
47. Waxman E.A., Lynch D.R. N-methyl-d-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase. J. Biol. Chem. 2005, 280:29322-29333.
48. Wingender E. The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation. Brief Bioinform. 2008, 9:326-332.
49. Zhang W., et al. GSK3beta modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner. Cell. Signal. 2009, 21:237-245.
50. Zhou M., Cui Y. GeneInfoViz: constructing and visualizing gene relation networks. In Silico Biol. 2004, 4:323-333.