Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder

Neuroscience Letters

Volumn 468, Issue 3, 2010, Pages 300-302

  Hashimoto, Ryota ^a,b   Hashimoto, Hitoshi ^a,c   Shintani, Norihito ^c   Ohi, Kazutaka ^a   Hori, Hiroaki ^b   Saitoh, Osamu ^d   Kosuga, Asako ^e   Tatsumi, Masahiko ^f   Iwata, Nakao ^g   Ozaki, Norio ^h   Kamijima, Kunitoshi ^e   Baba, Akemichi ^c   Takeda, Masatoshi ^a   Kunugi, Hiroshi ^b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^e SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f Yokohama Shinryo Clinic   (Japan)

^g FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^h NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

ADCYAP1; Depression; Major depressive disorder; PACAP; Single nucleotide polymorphism

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; PATHOGENESIS; PRIORITY JOURNAL; RISK FACTOR; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 72249116923     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.11.019     Document Type: Article

References (17)

1. Boyle M.P., Brewer J.A., Funatsu M., Wozniak D.F., Tsien J.Z., Izumi Y., and Muglia L.J. Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 473-478
2. Burke H.M., Davis M.C., Otte C., and Mohr D.C. Depression and cortisol responses to psychological stress: a meta-analysis. Psychoneuroendocrinology 30 (2005) 846-856
3. Ebmeier K.P., Donaghey C., and Steele J.D. Recent developments and current controversies in depression. Lancet 367 (2006) 153-167
4. Hashimoto H., Hashimoto R., Shintani N., Tanaka K., Yamamoto A., Hatanaka M., Guo X., Morita Y., Tanida M., Nagai K., Takeda M., and Baba A. Depression-like behavior in the forced swimming test in PACAP-deficient mice: amelioration by the atypical antipsychotic risperidone. J. Neurochem. 110 (2009) 595-602
5. Hashimoto H., Shintani N., and Baba A. New insights into the central PACAPergic system from the phenotypes in PACAP- and PACAP receptor-knockout mice. Ann. NY Acad. Sci. 1070 (2006) 75-89
6. Hashimoto H., Shintani N., Tanaka K., Mori W., Hirose M., Matsuda T., Sakaue M., Miyazaki J., Niwa H., Tashiro F., Yamamoto K., Koga K., Tomimoto S., Kunugi A., Suetake S., and Baba A. Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP). Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 13355-13360
7. Hashimoto R., Hashimoto H., Shintani N., Chiba S., Hattori S., Okada T., Nakajima M., Tanaka K., Kawagishi N., Nemoto K., Mori T., Ohnishi T., Noguchi H., Hori H., Suzuki T., Iwata N., Ozaki N., Nakabayashi T., Saitoh O., Kosuga A., Tatsumi M., Kamijima K., Weinberger D.R., Kunugi H., and Baba A. Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia. Mol. Psychiatry 12 (2007) 1026-1032
8. Hashimoto R., Numakawa T., Ohnishi T., Kumamaru E., Yagasaki Y., Ishimoto T., Mori T., Nemoto K., Adachi N., Izumi A., Chiba S., Noguchi H., Suzuki T., Iwata N., Ozaki N., Taguchi T., Kamiya A., Kosuga A., Tatsumi M., Kamijima K., Weinberger D.R., Sawa A., and Kunugi H. Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Hum. Mol. Genet. 15 (2006) 3024-3033
9. Hashimoto R., Okada T., Kato T., Kosuga A., Tatsumi M., Kamijima K., and Kunugi H. The breakpoint cluster region gene on chromosome 22q11 is associated with bipolar disorder. Biol. Psychiatry 57 (2005) 1097-1102
10. Hashimoto R., Suzuki T., Iwata N., Yamanouchi Y., Kitajima T., Kosuga A., Tatsumi M., Ozaki N., Kamijima K., and Kunugi H. Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders. J. Neural. Transm. 112 (2005) 303-307
11. Hattori T., Baba K., Matsuzaki S., Honda A., Miyoshi K., Inoue K., Taniguchi M., Hashimoto H., Shintani N., Baba A., Shimizu S., Yukioka F., Kumamoto N., Yamaguchi A., Tohyama M., and Katayama T. A novel DISC1-interacting partner DISC1-binding zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth. Mol. Psychiatry 12 (2007) 398-407
12. Millar J.K., Wilson-Annan J.C., Anderson S., Christie S., Taylor M.S., Semple C.A., Devon R.S., Clair D.M., Muir W.J., Blackwood D.H., and Porteous D.J. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum. Mol. Genet. 9 (2000) 1415-1423
13. Nurnberger Jr. J.I., and Foroud T. Genetics of bipolar affective disorder. Curr. Psychiatry Rep. 2 (2000) 147-157
14. Sheline Y.I., Wang P.W., Gado M.H., Csernansky J.G., and Vannier M.W. Hippocampal atrophy in recurrent major depression. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 3908-3913
15. Shelton R.C., Tollefson G.D., Tohen M., Stahl S., Gannon K.S., Jacobs T.G., Buras W.R., Bymaster F.P., Zhang W., Spencer K.A., Feldman P.D., and Meltzer H.Y. A novel augmentation strategy for treating resistant major depression. Am. J. Psychiatry 158 (2001) 131-134
16. Tanaka K., Shintani N., Hashimoto H., Kawagishi N., Ago Y., Matsuda T., Hashimoto R., Kunugi H., Yamamoto A., Kawaguchi C., Shimada T., and Baba A. Psychostimulant-induced attenuation of hyperactivity and prepulse inhibition deficits in Adcyap1-deficient mice. J. Neurosci. 26 (2006) 5091-5097
17. Thomson F., and Craighead M. Innovative approaches for the treatment of depression: targeting the HPA axis. Neurochem. Res. 33 (2008) 691-707