Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia

Development

Volumn 130, Issue 10, 2003, Pages 2275-2287

  Ligon, Keith L ^a,b,c   Echelard, Yann ^d   Assimacopoulos, Stavroula ^e   Danielian, Paul S ^f   Kaing, Sovann ^a   Grove, Elizabeth A ^e   McMahon, Andrew P ^f   Rowitch, David H ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d GTC Biotherapeutics Inc   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

^f HARVARD UNIVERSITY   (United States)

Author keywords

Cerebral; Cortex; Cortical hem; Dysplasia; Emx2; Glioneuronal; Heterotopia; Leptomeningeal; Marginal zone; Organizer; Preplate; Subplate; Telencephalon; Transgenic; Wnt1

Indexed keywords

CALRETININ; HOMEODOMAIN PROTEIN; PROTEIN EMX2; REELIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; BINDING SITE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN MALFORMATION; CELL MIGRATION; CELL POPULATION; CONTROLLED STUDY; CORTICAL DYSPLASIA; EMBRYO; EMBRYONIC STRUCTURES; ENHANCER REGION; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENE TARGETING; GENETIC CODE; HETEROTOPIA; HUMAN; LEPTOMENINX; MOUSE; NERVE CELL; NEUROECTODERM; NONHUMAN; NULL ALLELE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DNA BINDING; REVIEW; TELENCEPHALON; TRANSGENIC MOUSE;

ANIMALS; BINDING SITES; CHORISTOMA; EMBRYO; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; HUMANS; IN SITU HYBRIDIZATION; MENINGES; MICE; MICE, TRANSGENIC; NEUROGLIA; NEURONS; PROTO-ONCOGENE PROTEINS; TELENCEPHALON; TRANSCRIPTION FACTORS; TRANSGENES; WNT PROTEINS; WNT1 PROTEIN; ZEBRAFISH PROTEINS;

ANIMALIA; MAMMALIA; MURINAE; MUS MUSCULUS;

EID: 0037797434     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00421     Document Type: Review

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