메뉴 건너뛰기




Volumn 118, Issue 24, 2008, Pages 2506-2514

Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: Insights from illustrate (investigation of lipid level management using coronary ultrasound to assess reduction of atherosclerosis by CETP inhibition and HDL elevation)

Author keywords

Atherosclerosis; High density lipoprotein cholesterol; Torcetrapib; Ultrasonics

Indexed keywords

ATORVASTATIN; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; POTASSIUM; SODIUM; TORCETRAPIB; HEPTANOIC ACID DERIVATIVE; HIGH DENSITY LIPOPROTEIN; PYRROLE DERIVATIVE; QUINOLINE DERIVATIVE;

EID: 58149386896     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.790733     Document Type: Article
Times cited : (192)

References (50)
  • 5
    • 58149384364 scopus 로고    scopus 로고
    • In interests of patient safety, Pfizer stops all torcetrapib clinical trials; company has notified FDA and is in the process of notifying all clinical investigators and other regulatory authorities [press release]. New York, NY: Pfizer; December 2, 2006.
    • In interests of patient safety, Pfizer stops all torcetrapib clinical trials; company has notified FDA and is in the process of notifying all clinical investigators and other regulatory authorities [press release]. New York, NY: Pfizer; December 2, 2006.
  • 6
    • 33846424247 scopus 로고    scopus 로고
    • The failure of torcetrapib: Was it the molecule or the mechanism?
    • Tall AR, Yvan-Charvet L, Wang N. The failure of torcetrapib: was it the molecule or the mechanism? Arterioscler Thromb Vasc Biol. 2007;27:257-260.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 257-260
    • Tall, A.R.1    Yvan-Charvet, L.2    Wang, N.3
  • 9
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994;74:1141-1148.
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 10
    • 2442490850 scopus 로고    scopus 로고
    • Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: A possible role for angiotensin- converting enzyme and the receptors for angiotensin Π and aldosterone
    • Keidar S, Kaplan M, Pavlotzky E, Coleman R, Hayek T, Hamoud S, Aviram M. Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin- converting enzyme and the receptors for angiotensin Π and aldosterone. Circulation. 2004;109:2213-2220.
    • (2004) Circulation , vol.109 , pp. 2213-2220
    • Keidar, S.1    Kaplan, M.2    Pavlotzky, E.3    Coleman, R.4    Hayek, T.5    Hamoud, S.6    Aviram, M.7
  • 12
    • 0037035471 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonism in experimental atherosclerosis
    • Rajagopalan S, Duquaine D, King S, Pitt B, Patel P. Mineralocorticoid receptor antagonism in experimental atherosclerosis. Circulation. 2002;105:2212-2216.
    • (2002) Circulation , vol.105 , pp. 2212-2216
    • Rajagopalan, S.1    Duquaine, D.2    King, S.3    Pitt, B.4    Patel, P.5
  • 13
  • 14
    • 33646692656 scopus 로고    scopus 로고
    • Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation
    • Suzuki J, Iwai M, Mogi M, Oshita A, Yoshii T, Higaki J, Horiuchi M. Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation. Arterioscler Thromb Vasc Biol. 2006;26:917-921.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 917-921
    • Suzuki, J.1    Iwai, M.2    Mogi, M.3    Oshita, A.4    Yoshii, T.5    Higaki, J.6    Horiuchi, M.7
  • 20
    • 0032570684 scopus 로고    scopus 로고
    • Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits
    • Sugano M, Makino N, Sawada S, Otsuka S, Watanabe M, Okamoto H, Kamada M, Mizushima A. Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits. J Biol Chem. 1998;273:5033-5036.
    • (1998) J Biol Chem , vol.273 , pp. 5033-5036
    • Sugano, M.1    Makino, N.2    Sawada, S.3    Otsuka, S.4    Watanabe, M.5    Okamoto, H.6    Kamada, M.7    Mizushima, A.8
  • 22
    • 0034644214 scopus 로고    scopus 로고
    • A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
    • Okamoto H, Yonemori F, Wakitani K, Minowa T, Maeda K, Shinkai H. A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature. 2000;406:203-207.
    • (2000) Nature , vol.406 , pp. 203-207
    • Okamoto, H.1    Yonemori, F.2    Wakitani, K.3    Minowa, T.4    Maeda, K.5    Shinkai, H.6
  • 23
    • 33750477286 scopus 로고    scopus 로고
    • Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels
    • Davidson MH, McKenney JM, Shear CL, Revkin JH. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels. J Am Coll Cardiol. 2006;48:1774-1781.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1774-1781
    • Davidson, M.H.1    McKenney, J.M.2    Shear, C.L.3    Revkin, J.H.4
  • 25
    • 19944431793 scopus 로고    scopus 로고
    • Boekholdt SM, Sacks FM, Jukema JW, Shepherd J, Freeman DJ, McMahon AD, Cambien F, Nicaud V, de Groom GJ, Talmud PJ, Humphries SE, Miller GJ, Eiriksdottir G, Gudnason V, Kauma H, Kakko S, Savolainen MJ, Area M, Montali A, Liu S, Lanz HJ, Zwinderman AH, Kuivenhoven JA, Kastelein JJ. Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13 677 subjects. Circulation. 2005;111:278-287.
    • Boekholdt SM, Sacks FM, Jukema JW, Shepherd J, Freeman DJ, McMahon AD, Cambien F, Nicaud V, de Groom GJ, Talmud PJ, Humphries SE, Miller GJ, Eiriksdottir G, Gudnason V, Kauma H, Kakko S, Savolainen MJ, Area M, Montali A, Liu S, Lanz HJ, Zwinderman AH, Kuivenhoven JA, Kastelein JJ. Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13 677 subjects. Circulation. 2005;111:278-287.
  • 27
    • 0029948968 scopus 로고    scopus 로고
    • Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels
    • Zhong S, Sharp DS, Grove JS, Bruce C, Yano K, Curb JD, Tall AR. Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels. J Clin Invest. 1996;97:2917-2923.
    • (1996) J Clin Invest , vol.97 , pp. 2917-2923
    • Zhong, S.1    Sharp, D.S.2    Grove, J.S.3    Bruce, C.4    Yano, K.5    Curb, J.D.6    Tall, A.R.7
  • 28
    • 0038448097 scopus 로고    scopus 로고
    • Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux
    • Wang N, Tall AR. Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux. Arterioscler Thromb Vasc Biol. 2003;23:1178-1184.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1178-1184
    • Wang, N.1    Tall, A.R.2
  • 30
    • 33646409606 scopus 로고    scopus 로고
    • HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway
    • Matsuura F, Wang N, Chen W, Jiang XC, Tall AR. HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway. J Clin Invest. 2006;116:1435-1442.
    • (2006) J Clin Invest , vol.116 , pp. 1435-1442
    • Matsuura, F.1    Wang, N.2    Chen, W.3    Jiang, X.C.4    Tall, A.R.5
  • 33
    • 33646689775 scopus 로고    scopus 로고
    • Effect of inhibiting cholesteryl ester transfer protein on the kinetics of high-density lipoprotein cholesteryl ester transport in plasma: In vivo studies in rabbits
    • Kee P, Caiazza D, Rye KA, Barrett PH, Morehouse LA, Barter PJ. Effect of inhibiting cholesteryl ester transfer protein on the kinetics of high-density lipoprotein cholesteryl ester transport in plasma: in vivo studies in rabbits. Arterioscler Thromb Vasc Biol. 2006;26:884-890.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 884-890
    • Kee, P.1    Caiazza, D.2    Rye, K.A.3    Barrett, P.H.4    Morehouse, L.A.5    Barter, P.J.6
  • 34
    • 0017384270 scopus 로고
    • High density lipoprotein as a protective factor against coronary heart disease: The Framingham Study
    • Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease: the Framingham Study. Am J Med. 1977;62:707-714.
    • (1977) Am J Med , vol.62 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3    Kannel, W.B.4    Dawber, T.R.5
  • 35
    • 0025322265 scopus 로고
    • Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit
    • Badimon JJ, Badimon L, Fuster V. Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit. J Clin Invest. 1990;85:1234-1241.
    • (1990) J Clin Invest , vol.85 , pp. 1234-1241
    • Badimon, J.J.1    Badimon, L.2    Fuster, V.3
  • 36
    • 0024550898 scopus 로고
    • High density lipoprotein plasma fractions inhibit aortic fatty streaks in cholesterol-fed rabbits
    • Badimon JJ, Badimon L, Galvez A, Dische R, Fuster V. High density lipoprotein plasma fractions inhibit aortic fatty streaks in cholesterol-fed rabbits. Lab Invest. 1989;60:455-461.
    • (1989) Lab Invest , vol.60 , pp. 455-461
    • Badimon, J.J.1    Badimon, L.2    Galvez, A.3    Dische, R.4    Fuster, V.5
  • 37
    • 0028025262 scopus 로고
    • Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse
    • Plump AS, Scott CJ, Breslow JL. Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc Nat Acad Sci USA. 1994;91:9607-9611.
    • (1994) Proc Nat Acad Sci USA , vol.91 , pp. 9607-9611
    • Plump, A.S.1    Scott, C.J.2    Breslow, J.L.3
  • 38
    • 0025902231 scopus 로고
    • Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI
    • Rubin EM, Krauss RM, Spangler EA, Verstuyft JG, Clift SM. Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI. Nature. 1991;353:265-267.
    • (1991) Nature , vol.353 , pp. 265-267
    • Rubin, E.M.1    Krauss, R.M.2    Spangler, E.A.3    Verstuyft, J.G.4    Clift, S.M.5
  • 40
    • 0035856550 scopus 로고    scopus 로고
    • Elevating high-density lipoprotein cholesterol in apolipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content
    • Rong JX, Li J, Reis ED, Choudhury RP, Dansky HM, Elmalem VI, Fallon JT, Breslow JL, Fisher EA. Elevating high-density lipoprotein cholesterol in apolipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content. Circulation. 2001;104:2447-2452.
    • (2001) Circulation , vol.104 , pp. 2447-2452
    • Rong, J.X.1    Li, J.2    Reis, E.D.3    Choudhury, R.P.4    Dansky, H.M.5    Elmalem, V.I.6    Fallon, J.T.7    Breslow, J.L.8    Fisher, E.A.9
  • 41
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360:7-22.
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360:7-22.
  • 42
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 43
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS: Air Force/Texas Coronary Atherosclerosis Prevention Study
    • Downs JR, Clearfield M, Weis S, Whitney E, Shapiro DR, Beere PA, Largendorfer A, Stein EA, Kruyer W, Gotto AM Jr. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS: Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA. 1998;279:1615-1622.
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3    Whitney, E.4    Shapiro, D.R.5    Beere, P.A.6    Largendorfer, A.7    Stein, E.A.8    Kruyer, W.9    Gotto Jr., A.M.10
  • 45
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary-prevention trial with gemfibrozil in middle aged men with dyslipidemia: safety of treatment, changes in risk factors and incidence of coronary heart disease
    • Frick MH, Elo O, Haapa K, Heinonen OD, Heinsalmi P, Helo P, Huttunen JK, Kaitaniemi P, Koskinen P, Manninen V. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle aged men with dyslipidemia: safety of treatment, changes in risk factors and incidence of coronary heart disease. N Engl J Med. 1987;317:1237-1245.
    • (1987) N Engl J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3    Heinonen, O.D.4    Heinsalmi, P.5    Helo, P.6    Huttunen, J.K.7    Kaitaniemi, P.8    Koskinen, P.9    Manninen, V.10
  • 47
    • 0016630250 scopus 로고
    • Clofibrate and niacin in coronary heart disease
    • Clofibrate and niacin in coronary heart disease. JAMA. 1975;231:360-381.
    • (1975) JAMA , vol.231 , pp. 360-381


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.