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Volumn 1, Issue 2, 2010, Pages

Buccoadhesive drug delivery systems: A review

Author keywords

Buccoadhesive drug delivery; Mucoadhesion; Polymers

Indexed keywords

LECTIN; POLYMER;

EID: 81255170564     PISSN: None     EISSN: 09756299     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (10)

References (172)
  • 2
    • 33947681178 scopus 로고    scopus 로고
    • Formulation, evaluation, and comparison of bilayered and multilayered mucoadhesive buccal devices of propranolol hydrochloride
    • V. M. Patel, B. G. Prajapati, M. M. Patel. Formulation, evaluation, and comparison of bilayered and multilayered mucoadhesive buccal devices of propranolol hydrochloride. AAPS PharmSciTech 8(1):E1-8 (2007).
    • (2007) AAPS PharmSciTech , vol.8 , Issue.1
    • Patel, V.M.1    Prajapati, B.G.2    Patel, M.M.3
  • 3
    • 26644444777 scopus 로고    scopus 로고
    • The use of mucoadhesive polymers in buccal drug delivery
    • N. S. Miller, M. Chittchang, T. P. Johnston. The use of mucoadhesive polymers in buccal drug delivery. Adv Drug Deliv Rev 57:1666-91 (2005).
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1666-1691
    • Miller, N.S.1    Chittchang, M.2    Johnston, T.P.3
  • 5
    • 0031597891 scopus 로고    scopus 로고
    • Buccal mucosa as a route for systemic drug delivery: A review
    • A. H. Shojaei. Buccal mucosa as a route for systemic drug delivery: A review. J Pharm Pharm Sci 1(1):15-30 (1998).
    • (1998) J Pharm Pharm Sci , vol.1 , Issue.1 , pp. 15-30
    • Shojaei, A.H.1
  • 6
    • 0002149081 scopus 로고
    • The ultrastructure of the oral epithelium
    • J. Meyer, C. A. Squier, S. J. Gerson (eds.), Pergamon Press, Oxford
    • Y. S. Chen, C. A. Squier. The ultrastructure of the oral epithelium. In: J. Meyer, C. A. Squier, S. J. Gerson (eds.), The structure and function of oral mucosa, Pergamon Press, Oxford, 1984, pp. 7-30.
    • (1984) The structure and function of oral mucosa , pp. 7-30
    • Chen, Y.S.1    Squier, C.A.2
  • 7
    • 0026564618 scopus 로고
    • Drug delivery via the mucous membranes of the oral cavity
    • D. Harris, J. R. Robinson. Drug delivery via the mucous membranes of the oral cavity. J Pharm Sci 81:1-10 (1992).
    • (1992) J Pharm Sci , vol.81 , pp. 1-10
    • Harris, D.1    Robinson, J.R.2
  • 8
    • 0008986338 scopus 로고
    • A comparison of human palatal and buccal mucosa
    • J. Meyer, S. J. Gerson. A comparison of human palatal and buccal mucosa. Periodontics 2:284-91 (1964).
    • (1964) Periodontics , vol.2 , pp. 284-291
    • Meyer, J.1    Gerson, S.J.2
  • 9
    • 0028123427 scopus 로고
    • Oral cavity as a site for bioadhesive drug delivery
    • R. B. Gandhi, J. R. Robinson. Oral cavity as a site for bioadhesive drug delivery. Adv Drug Deliv Rev 13:43-74 (1994).
    • (1994) Adv Drug Deliv Rev , vol.13 , pp. 43-74
    • Gandhi, R.B.1    Robinson, J.R.2
  • 10
    • 0345240620 scopus 로고
    • The vascular system and blood supply
    • J. Meyer, C. A. Squier, S. J. Gerson (eds.), Pergamon Press, Oxford
    • M. J. Stablein, J. Meyer. The vascular system and blood supply. In: J. Meyer, C. A. Squier, S. J. Gerson (eds.), The structure and function of oral mucosa, Pergamon Press, Oxford, 1984, pp. 237-56.
    • (1984) The structure and function of oral mucosa , pp. 237-256
    • Stablein, M.J.1    Meyer, J.2
  • 11
    • 4243574367 scopus 로고
    • Mucus and mucosal protection
    • A. Allen, G. Flemström, A. Garner, W. Silen, L. A. Turnberg (eds.), Raven Press, New York
    • A. Allen, A. Bell, S. McQueen. Mucus and mucosal protection. In: A. Allen, G. Flemström, A. Garner, W. Silen, L. A. Turnberg (eds.), Mechanisms of mucosal protection in the upper gastrointestinal tract, Raven Press, New York, 1984, pp. 195-202.
    • (1984) Mechanisms of mucosal protection in the upper gastrointestinal tract , pp. 195-202
    • Allen, A.1    Bell, A.2    McQueen, S.3
  • 12
    • 60749111451 scopus 로고    scopus 로고
    • Mucoadhesive polymeric platforms for controlled drug delivery
    • G. P. Andrews, T. P. Laverty, D. S. Jones. Mucoadhesive polymeric platforms for controlled drug delivery. Eur J Pharm Biopharm 71:505-18 (2009).
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 505-518
    • Andrews, G.P.1    Laverty, T.P.2    Jones, D.S.3
  • 13
    • 0030037291 scopus 로고    scopus 로고
    • From sticky stuff to sweet receptors-achievements, limits and novel approaches to bioadhesion
    • C. M. Lehr. From sticky stuff to sweet receptors-achievements, limits and novel approaches to bioadhesion. Eur J Drug Metab Pharmacokinet 21:139-48 (1996).
    • (1996) Eur J Drug Metab Pharmacokinet , vol.21 , pp. 139-148
    • Lehr, C.M.1
  • 14
    • 0036238911 scopus 로고    scopus 로고
    • Developments in the area of bioadhesive drug delivery systems
    • J. Haas, C. M. Lehr. Developments in the area of bioadhesive drug delivery systems. Expert Opin Biol Ther 2:287-98 (2002).
    • (2002) Expert Opin Biol Ther , vol.2 , pp. 287-298
    • Haas, J.1    Lehr, C.M.2
  • 15
    • 0029408163 scopus 로고
    • Transmission electron microscopy studies on pig gastric mucin and its interactions with chitosan
    • I. Fiebrig, S. Harding, A. Rowe, S. Hyman, S. Davis. Transmission electron microscopy studies on pig gastric mucin and its interactions with chitosan. Carbohydr Polym 28:239-44 (1995).
    • (1995) Carbohydr Polym , vol.28 , pp. 239-244
    • Fiebrig, I.1    Harding, S.2    Rowe, A.3    Hyman, S.4    Davis, S.5
  • 16
    • 61349153560 scopus 로고    scopus 로고
    • Engineering design and molecular dynamics of mucoadhesive drug delivery systems as targeting agents
    • L. Serra, J. Doménech, N. A. Peppas. Engineering design and molecular dynamics of mucoadhesive drug delivery systems as targeting agents. Eur J Pharm Biopharm 71:519-28 (2009).
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 519-528
    • Serra, L.1    Doménech, J.2    Peppas, N.A.3
  • 17
    • 0035284437 scopus 로고    scopus 로고
    • Synthetic polymers alter the structure of cervical mucus
    • R. Willits, W. M. Saltzman. Synthetic polymers alter the structure of cervical mucus. Biomaterials 22:445-52 (2001).
    • (2001) Biomaterials , vol.22 , pp. 445-452
    • Willits, R.1    Saltzman, W.M.2
  • 18
    • 0018653916 scopus 로고
    • Membrane-coating granules
    • A. F. Hayward. Membrane-coating granules. Int Rev Cyt 59:97-127 (1979).
    • (1979) Int Rev Cyt , vol.59 , pp. 97-127
    • Hayward, A.F.1
  • 19
    • 0018141903 scopus 로고
    • The permeability of epidermis lacking normal membrane-coating granules: an ultrastructural tracer study of Kyrle-Flegel disease
    • C. A. Squier, R. A. Eady, R. M. Hopps. The permeability of epidermis lacking normal membrane-coating granules: an ultrastructural tracer study of Kyrle-Flegel disease. J Invest Dermatol 70:361-64 (1978).
    • (1978) J Invest Dermatol , vol.70 , pp. 361-364
    • Squier, C.A.1    Eady, R.A.2    Hopps, R.M.3
  • 20
    • 0342737897 scopus 로고
    • Permeability of the oral mucosa
    • C. A. Squier, J. Meyer (eds.), Springfield, IL: Carles Thomas;
    • I. A. Siegel, S. H. Hall, R. Stambaugh. Permeability of the oral mucosa. In: C. A. Squier, J. Meyer (eds.), Current concepts of the histology of oral mucosa, Springfield, IL: Carles Thomas; 1971, pp. 274-86.
    • (1971) Current concepts of the histology of oral mucosa , pp. 274-286
    • Siegel, I.A.1    Hall, S.H.2    Stambaugh, R.3
  • 21
    • 0032783827 scopus 로고    scopus 로고
    • Carriermediated transport systems for glucose in mucosal cells of the human oral cavity
    • Y. Oyama, H. Yamano, A. Ohkuma, K. Ogawara, K. Higaki, T. Kimura. Carriermediated transport systems for glucose in mucosal cells of the human oral cavity. J Pharm Sci 88:830-34 (1999).
    • (1999) J Pharm Sci , vol.88 , pp. 830-834
    • Oyama, Y.1    Yamano, H.2    Ohkuma, A.3    Ogawara, K.4    Higaki, K.5    Kimura, T.6
  • 22
    • 0030893941 scopus 로고    scopus 로고
    • Carrier-mediated transport of monocarboxylic acids in primary cultured epithelial cells from rabbit oral mucosa
    • N. Utoguchi, Y. Watanabe, T. Suzuki, J. Maehara, Y. Matsumoto, M. Matsumoto. Carrier-mediated transport of monocarboxylic acids in primary cultured epithelial cells from rabbit oral mucosa. Pharm Res 14:320-24 (1997).
    • (1997) Pharm Res , vol.14 , pp. 320-324
    • Utoguchi, N.1    Watanabe, Y.2    Suzuki, T.3    Maehara, J.4    Matsumoto, Y.5    Matsumoto, M.6
  • 23
    • 0032906292 scopus 로고    scopus 로고
    • Carrier-mediated absorption of salicylic acid from hamster cheek pouch mucosa
    • N. Utoguchi, Y. Watanabe, Y. Takase, T. Suzuki, Matsumoto M. Carrier-mediated absorption of salicylic acid from hamster cheek pouch mucosa. J Pharm Sci 88:142-46 (1999).
    • (1999) J Pharm Sci , vol.88 , pp. 142-146
    • Utoguchi, N.1    Watanabe, Y.2    Takase, Y.3    Suzuki, T.4    Matsumoto, M.5
  • 24
    • 0019532966 scopus 로고
    • Absorption of amino acids from the human buccal cavity
    • D. F. Evered, J. V. Vadgama. Absorption of amino acids from the human buccal cavity. Biochem Soc Trans 9:132-33 (1981).
    • (1981) Biochem Soc Trans , vol.9 , pp. 132-133
    • Evered, D.F.1    Vadgama, J.V.2
  • 25
    • 0020530541 scopus 로고
    • Thiamine absorption across human buccal mucosa in vivo
    • D. F. Evered, C. Mallett. Thiamine absorption across human buccal mucosa in vivo. Life Sci 32:1355-58 (1983).
    • (1983) Life Sci , vol.32 , pp. 1355-1358
    • Evered, D.F.1    Mallett, C.2
  • 26
    • 0006708325 scopus 로고    scopus 로고
    • Absorption enhancers
    • J. Swarbrick, J. C. Boylan (eds.), Marcel Dekker Inc., New York
    • J. R. Robinson, X. Yang. Absorption enhancers. In: J. Swarbrick, J. C. Boylan (eds.), Encyclopedia of pharmaceutical technology, Marcel Dekker Inc., New York, 2001, vol 18, pp. 1-27.
    • (2001) Encyclopedia of pharmaceutical technology , vol.18 , pp. 1-27
    • Robinson, J.R.1    Yang, X.2
  • 28
    • 0037148692 scopus 로고    scopus 로고
    • Peptidase acitivity on the surface of the porcine buccal mucosa
    • G. F. Walker, N. Langoth, A. Bernkop-Schnürch. Peptidase acitivity on the surface of the porcine buccal mucosa. Int J Pharm 233:141-47 (2002).
    • (2002) Int J Pharm , vol.233 , pp. 141-147
    • Walker, G.F.1    Langoth, N.2    Bernkop-Schnürch, A.3
  • 29
    • 0022460440 scopus 로고
    • Enkephalin hydrolysis in homogenates of various absorptive mucosae of the albino rabbit: similarities in rates and involvement of aminopeptidases
    • S. D. Kashi, V. H. L. Lee. Enkephalin hydrolysis in homogenates of various absorptive mucosae of the albino rabbit: similarities in rates and involvement of aminopeptidases. Life Sci 38:2019-28 (1986).
    • (1986) Life Sci , vol.38 , pp. 2019-2028
    • Kashi, S.D.1    Lee, V.H.L.2
  • 30
    • 0023007254 scopus 로고
    • Fundamental aspects of bioadhesion
    • M. A. Longer, J. R. Robinson. Fundamental aspects of bioadhesion. Pharm. Int. 7:114-17 (1986).
    • (1986) Pharm. Int. , vol.7 , pp. 114-117
    • Longer, M.A.1    Robinson, J.R.2
  • 31
    • 0023917757 scopus 로고    scopus 로고
    • Binding of acrylic polymers to mucin/epithelial surfaces: structure-property relationships
    • J. M. Gu, J. R. Robinson, S. H. S. Leung. Binding of acrylic polymers to mucin/epithelial surfaces: structure-property relationships. Crit Rev Ther Drug Carr Syst 5:21-67 (1998).
    • (1998) Crit Rev Ther Drug Carr Syst , vol.5 , pp. 21-67
    • Gu, J.M.1    Robinson, J.R.2    Leung, S.H.S.3
  • 32
    • 0022402037 scopus 로고
    • Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues
    • N. A.. Peppas, P. A. Buri. Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues. J Control Release 2:257-75 (1985).
    • (1985) J Control Release , vol.2 , pp. 257-275
    • Peppas, N.A.1    Buri, P.A.2
  • 33
    • 0030902837 scopus 로고    scopus 로고
    • Mucoadhesive drug delivery systems
    • A. Ahuja, R. K. Khar, J. Ali. Mucoadhesive drug delivery systems. Drug Dev Ind Pharm 23:489-515 (1997).
    • (1997) Drug Dev Ind Pharm , vol.23 , pp. 489-515
    • Ahuja, A.1    Khar, R.K.2    Ali, J.3
  • 34
    • 0034000923 scopus 로고    scopus 로고
    • Molecular aspects of muco- and bioadhesion: tethered structures and sitespecific surfaces
    • Y. Huang, W. Leobandung, A. Foss, N. A. Peppas. Molecular aspects of muco- and bioadhesion: tethered structures and sitespecific surfaces. J Control Release 65:63-71 (2000).
    • (2000) J Control Release , vol.65 , pp. 63-71
    • Huang, Y.1    Leobandung, W.2    Foss, A.3    Peppas, N.A.4
  • 35
    • 0001587789 scopus 로고
    • Effect of interfacial bonding on the strength of adhesion
    • A. Ahagon, A. N. Gent. Effect of interfacial bonding on the strength of adhesion. J Polym Sci Polym Phys 13:1285-1300 (1975).
    • (1975) J Polym Sci Polym Phys , vol.13 , pp. 1285-1300
    • Ahagon, A.1    Gent, A.N.2
  • 36
    • 0019056719 scopus 로고
    • The science of adhesion
    • A. J. Kinloch. The science of adhesion. J Mater Sci 15:2141-66 (1980).
    • (1980) J Mater Sci , vol.15 , pp. 2141-2166
    • Kinloch, A.J.1
  • 37
    • 0033813758 scopus 로고    scopus 로고
    • Bioadhesive-based dosage forms: the next generation
    • J. W. Lee, J. H. Park, J. R. Robinson. Bioadhesive-based dosage forms: the next generation. J Pharm Sci 89:850-66 (2000).
    • (2000) J Pharm Sci , vol.89 , pp. 850-866
    • Lee, J.W.1    Park, J.H.2    Robinson, J.R.3
  • 38
    • 17444372009 scopus 로고    scopus 로고
    • Mucoadhesives in the gastrointestinal tract: revisiting the literature for novel applications
    • D. Dodou, P. Breedveld, P. Wieringa. Mucoadhesives in the gastrointestinal tract: revisiting the literature for novel applications. Eur J Pharm Biopharm 60:1-16 (2005).
    • (2005) Eur J Pharm Biopharm , vol.60 , pp. 1-16
    • Dodou, D.1    Breedveld, P.2    Wieringa, P.3
  • 39
    • 26644434124 scopus 로고    scopus 로고
    • Nasal mucoadhesive drug delivery: background, applications, trends and future perspectives
    • M. I. Ugwoke, R. U. Agu, N. Verbeke, R. Kinget. Nasal mucoadhesive drug delivery: background, applications, trends and future perspectives. Adv Drug Deliv Rev 57:1640-1665 (2005).
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1640-1665
    • Ugwoke, M.I.1    Agu, R.U.2    Verbeke, N.3    Kinget, R.4
  • 40
    • 0022368844 scopus 로고
    • Interaction of cultured human endothelial cells with polymeric surfaces of different wettabilities
    • P. B. van Wachem, T. Beugeling, J. Feijen, A. Bantjes, J. P. Detmers, W. G. van Aken. Interaction of cultured human endothelial cells with polymeric surfaces of different wettabilities. Biomaterials 6:403-8 (1985).
    • (1985) Biomaterials , vol.6 , pp. 403-408
    • van Wachem, P.B.1    Beugeling, T.2    Feijen, J.3    Bantjes, A.4    Detmers, J.P.5    van Aken, W.G.6
  • 41
    • 0002308188 scopus 로고
    • Compositions producing adhesion through hydration
    • R. S. Manly (ed.), Academic Press, New York
    • J. L. Chen, G. N. Cyr. Compositions producing adhesion through hydration. In: R. S. Manly (ed.), Adhesion in biological systems, Academic Press, New York, 1970, pp. 163-80.
    • (1970) Adhesion in biological systems , pp. 163-180
    • Chen, J.L.1    Cyr, G.N.2
  • 42
    • 0023529793 scopus 로고
    • Mechanisms of mucoadhesion of poly(acrylic acid) hydrogels
    • H. Park, J. R. Robinson. Mechanisms of mucoadhesion of poly(acrylic acid) hydrogels. Pharm Res 4:457-64 (1987).
    • (1987) Pharm Res , vol.4 , pp. 457-464
    • Park, H.1    Robinson, J.R.2
  • 45
    • 0026800237 scopus 로고
    • In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers
    • C. M. Lehr, J. A. Bouwstra, E. H. Schacht, H. E. Junginger. In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int J Pharm 78:43-48 (1992).
    • (1992) Int J Pharm , vol.78 , pp. 43-48
    • Lehr, C.M.1    Bouwstra, J.A.2    Schacht, E.H.3    Junginger, H.E.4
  • 46
    • 0035712709 scopus 로고    scopus 로고
    • Effect of carbomer concentration and degree of neutralization on the mucoadhesive properties of polymer films
    • D. Solomonidou, K. Cremer, M. Krumme, J. Kreuter. Effect of carbomer concentration and degree of neutralization on the mucoadhesive properties of polymer films. J Biomater Sci Polym Ed 12:1191-1205 (2001).
    • (2001) J Biomater Sci Polym Ed , vol.12 , pp. 1191-1205
    • Solomonidou, D.1    Cremer, K.2    Krumme, M.3    Kreuter, J.4
  • 48
    • 0025846959 scopus 로고
    • An estimate of turnover time of intestinal mucus gel layer in the rat in situ loop
    • C. M. Lehr, F. G. J. Poelma, H. E. Junginger, J. J. Tukker. An estimate of turnover time of intestinal mucus gel layer in the rat in situ loop. Int J Pharm 70:235-40 (1991).
    • (1991) Int J Pharm , vol.70 , pp. 235-240
    • Lehr, C.M.1    Poelma, F.G.J.2    Junginger, H.E.3    Tukker, J.J.4
  • 49
    • 0017862114 scopus 로고
    • Intestinal mucins in health and disease
    • J. F. Forstner. Intestinal mucins in health and disease. Digestion 17:234-63 (1978).
    • (1978) Digestion , vol.17 , pp. 234-263
    • Forstner, J.F.1
  • 50
    • 0026824078 scopus 로고
    • (D) Routes of delivery: case studies. (3) Mechanistic insights to buccal delivery of proteinaceous substances
    • N. F. H. Ho, C. L. Barsuhn, P. S. Burton, H. P. Merkle. (D) Routes of delivery: case studies. (3) Mechanistic insights to buccal delivery of proteinaceous substances. Adv Drug Deliv Rev 8:197-235 (1992).
    • (1992) Adv Drug Deliv Rev , vol.8 , pp. 197-235
    • Ho, N.F.H.1    Barsuhn, C.L.2    Burton, P.S.3    Merkle, H.P.4
  • 51
    • 0033020555 scopus 로고    scopus 로고
    • Polymers with thiol groups: a new generation of mucoadhesive polymers
    • A. Bernkop-Schnürch, V. Schwarz, S. Steininger. Polymers with thiol groups: a new generation of mucoadhesive polymers. Pharm Res 16:876-81 (1999).
    • (1999) Pharm Res , vol.16 , pp. 876-881
    • Bernkop-Schnürch, A.1    Schwarz, V.2    Steininger, S.3
  • 52
    • 0037452411 scopus 로고    scopus 로고
    • Development of buccal drug delivery systems based on a thiolated polymer
    • N. Langoth, J. Kalbe, A. Bernkop-Schnürch. Development of buccal drug delivery systems based on a thiolated polymer. Int J Pharm 252:141-48 (2003).
    • (2003) Int J Pharm , vol.252 , pp. 141-148
    • Langoth, N.1    Kalbe, J.2    Bernkop-Schnürch, A.3
  • 53
    • 0036229558 scopus 로고    scopus 로고
    • Thiolated polymers: self-crosslinking properties of thiolated 450 kDa poly(acrylic acid) andtheir influence on mucoadhesion
    • M. K. Marschütz, A. Bernkop-Schnürch. Thiolated polymers: self-crosslinking properties of thiolated 450 kDa poly(acrylic acid) andtheir influence on mucoadhesion. Eur J Pharm Sci 15:387-94 (2002).
    • (2002) Eur J Pharm Sci , vol.15 , pp. 387-394
    • Marschütz, M.K.1    Bernkop-Schnürch, A.2
  • 54
    • 0034925740 scopus 로고    scopus 로고
    • Thiolated polymers-thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates
    • C. E. Kast, A. Bernkop-Schnürch. Thiolated polymers-thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates. Biomaterials 22:2345-52 (2001).
    • (2001) Biomaterials , vol.22 , pp. 2345-2352
    • Kast, C.E.1    Bernkop-Schnürch, A.2
  • 55
    • 0026802436 scopus 로고
    • The human MUC2 intestinal mucin has cycteinerich subdomains located both upstream and downstream of its central repetitive region
    • J. R. Gum Jr, J. W. Hicks, N. W. Toribara, E. M. Rothe, R. E. Lagace, Y. S. Kim. The human MUC2 intestinal mucin has cycteinerich subdomains located both upstream and downstream of its central repetitive region. J Biol Chem 267:21375-83 (1992).
    • (1992) J Biol Chem , vol.267 , pp. 21375-21383
    • Gum Jr., J.R.1    Hicks, J.W.2    Toribara, N.W.3    Rothe, E.M.4    Lagace, R.E.5    Kim, Y.S.6
  • 56
    • 0033996243 scopus 로고    scopus 로고
    • Lectin-mediated drug delivery: the second generation of bioadhesives
    • C. M. Lehr. Lectin-mediated drug delivery: the second generation of bioadhesives. J Control Release 65:19-29 (2000).
    • (2000) J Control Release , vol.65 , pp. 19-29
    • Lehr, C.M.1
  • 58
    • 0028788346 scopus 로고
    • Mucoadhesive polymers in peroral peptide drug delivery: II. Carbomer and polycarbophil are potent inhibitors of the intestinal proteolytic enzyme trypsin
    • H. L. Lueßen, J. C. Verhoef, G. Borchard, C. M. Lehr, A. G. de Bore, H. E. Junginger. Mucoadhesive polymers in peroral peptide drug delivery: II. Carbomer and polycarbophil are potent inhibitors of the intestinal proteolytic enzyme trypsin. Pharm Res 12:1293-98 (1995).
    • (1995) Pharm Res , vol.12 , pp. 1293-1298
    • Lueßen, H.L.1    Verhoef, J.C.2    Borchard, G.3    Lehr, C.M.4    de Bore, A.G.5    Junginger, H.E.6
  • 59
    • 0024552779 scopus 로고
    • Evaluation of laminated mucoadhesive patches for buccal drug delivery
    • R. Anders, H. P. Merkle. Evaluation of laminated mucoadhesive patches for buccal drug delivery. Int J Pharm 49:231-40 (1989).
    • (1989) Int J Pharm , vol.49 , pp. 231-240
    • Anders, R.1    Merkle, H.P.2
  • 61
    • 0035998952 scopus 로고    scopus 로고
    • Development and in vivo evaluation of buccal tablets prepared using danazolsulfobutylether 7 β-cyclodextrin (SBE 7) complexes
    • A. C. Jain, B. J. Aungst, M. C. Adeyeye. Development and in vivo evaluation of buccal tablets prepared using danazolsulfobutylether 7 β-cyclodextrin (SBE 7) complexes. J Pharm Sci 91:1659-68 (2002).
    • (2002) J Pharm Sci , vol.91 , pp. 1659-1668
    • Jain, A.C.1    Aungst, B.J.2    Adeyeye, M.C.3
  • 64
    • 0021963276 scopus 로고
    • Bioadhesive polymers as platforms for oral controlled drug delivery: II. Synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers
    • H. S. Ch'ng, H. Park, P. Kelly, J. R. Robinson. Bioadhesive polymers as platforms for oral controlled drug delivery: II. Synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers. J Pharm Sci 74:399-405 (1985).
    • (1985) J Pharm Sci , vol.74 , pp. 399-405
    • Ch'ng, H.S.1    Park, H.2    Kelly, P.3    Robinson, J.R.4
  • 65
    • 0022368327 scopus 로고
    • Physico-chemical properties of water insoluble polymers important to mucin epithelial adhesion
    • H. Park, J. R. Robinson. Physico-chemical properties of water insoluble polymers important to mucin epithelial adhesion. J Control Release 2:47-57 (1985).
    • (1985) J Control Release , vol.2 , pp. 47-57
    • Park, H.1    Robinson, J.R.2
  • 66
    • 20244366397 scopus 로고    scopus 로고
    • Oral solid dosage forms
    • A. R. Gennaro (editor). 20th ed. Lippincott Williams & Wilkins, Baltimore, MD
    • E. M. Rudnic, J. D. Schwartz. Oral solid dosage forms. In: A. R. Gennaro (editor). Remington: the science and practice of pharmacy, 20th ed. Lippincott Williams & Wilkins, Baltimore, MD, 2000, pp. 858-59.
    • (2000) Remington: the science and practice of pharmacy , pp. 858-859
    • Rudnic, E.M.1    Schwartz, J.D.2
  • 67
    • 0019971238 scopus 로고
    • Effect of poloxamer 407 gel on the miotic activity of pilocarpine nitrate in rabbits
    • S. C. Miller, M. D. Donovan. Effect of poloxamer 407 gel on the miotic activity of pilocarpine nitrate in rabbits. Int J Pharm 12:147-52 (1982).
    • (1982) Int J Pharm , vol.12 , pp. 147-152
    • Miller, S.C.1    Donovan, M.D.2
  • 68
    • 0033006296 scopus 로고    scopus 로고
    • Formulation and evaluation of controlled release Eudragit buccal patches
    • C. F. Wong, K. H. Yuen, K. K. Peh. Formulation and evaluation of controlled release Eudragit buccal patches. Int J Pharm 178:11-22 (1999).
    • (1999) Int J Pharm , vol.178 , pp. 11-22
    • Wong, C.F.1    Yuen, K.H.2    Peh, K.K.3
  • 71
    • 0008007785 scopus 로고
    • Gamma scintigraphic evaluation of precorneal clearance in human volunteers and in rabbits
    • G. Meseguer, R. Gurny, P. Buri. Gamma scintigraphic evaluation of precorneal clearance in human volunteers and in rabbits. Eur J Drug Metab Pharmacokinet 18:190-94 (1993).
    • (1993) Eur J Drug Metab Pharmacokinet , vol.18 , pp. 190-194
    • Meseguer, G.1    Gurny, R.2    Buri, P.3
  • 72
    • 0037237845 scopus 로고    scopus 로고
    • Sustained buccal delivery of the hydrophobic drug denbufylline using physically cross-linked palmitoyl glycol chitosan hydrogels
    • L. Martin, C. G. Wilson, F. Koosha, I. F. Uchegbu. Sustained buccal delivery of the hydrophobic drug denbufylline using physically cross-linked palmitoyl glycol chitosan hydrogels. Eur J Pharm Biopharm 55:35-45 (2003).
    • (2003) Eur J Pharm Biopharm , vol.55 , pp. 35-45
    • Martin, L.1    Wilson, C.G.2    Koosha, F.3    Uchegbu, I.F.4
  • 74
    • 0031690410 scopus 로고    scopus 로고
    • Transbuccal delivery of acyclovir: I. In vitro determination of routes of buccal transport
    • A. H. Shojaei, B. Berner, X. Li. Transbuccal delivery of acyclovir: I. In vitro determination of routes of buccal transport. Pharm Res 15:1182-88 (1998).
    • (1998) Pharm Res , vol.15 , pp. 1182-1188
    • Shojaei, A.H.1    Berner, B.2    Li, X.3
  • 75
    • 0032056608 scopus 로고    scopus 로고
    • Transbuccal delivery of acyclovir: II. Feasibility, system design, and in vitro permeation studies
    • A. H. Shojaei, S. L. Zhuo, X. Li. Transbuccal delivery of acyclovir: II. Feasibility, system design, and in vitro permeation studies. J Pharm Pharm Sci 1:66-73 (1998).
    • (1998) J Pharm Pharm Sci , vol.1 , pp. 66-73
    • Shojaei, A.H.1    Zhuo, S.L.2    Li, X.3
  • 76
    • 0038669001 scopus 로고    scopus 로고
    • Buccal delivery of acyclovir from films based on chitosan and polyacrylic acid
    • S. Rossi, G. Sandri, F. Ferrari, M. C. Bonferoni, C. Caramella. Buccal delivery of acyclovir from films based on chitosan and polyacrylic acid. Pharm Dev Technol 8:199-208 (2003).
    • (2003) Pharm Dev Technol , vol.8 , pp. 199-208
    • Rossi, S.1    Sandri, G.2    Ferrari, F.3    Bonferoni, M.C.4    Caramella, C.5
  • 78
    • 0033050173 scopus 로고    scopus 로고
    • Development and in vitro evaluation of buccoadhesive tablets using a new model substrate for bioadhesion measures: the eggshell membrane
    • B. Parodi, E. Russo, P. Gatti, S. Cafaggi, G. Bignardi. Development and in vitro evaluation of buccoadhesive tablets using a new model substrate for bioadhesion measures: the eggshell membrane. Drug Dev Ind Pharm 25:289-95 (1999).
    • (1999) Drug Dev Ind Pharm , vol.25 , pp. 289-295
    • Parodi, B.1    Russo, E.2    Gatti, P.3    Cafaggi, S.4    Bignardi, G.5
  • 79
    • 0028153112 scopus 로고
    • Bioadhesive polymer buccal patches for buprenorphine controlled delivery: formulation, in-vitro adhesion and release properties
    • J. H. Guo. Bioadhesive polymer buccal patches for buprenorphine controlled delivery: formulation, in-vitro adhesion and release properties. Drug Dev Ind Pharm 20:2809-21 (1994).
    • (1994) Drug Dev Ind Pharm , vol.20 , pp. 2809-2821
    • Guo, J.H.1
  • 80
    • 0029980045 scopus 로고    scopus 로고
    • The effects of backing materials and multilayered systems on the characteristics of bioadhesive buccal patches
    • J. H. Guo, K. M. Cooklock. The effects of backing materials and multilayered systems on the characteristics of bioadhesive buccal patches. J Pharm Pharmacol 48:255-57 (1996).
    • (1996) J Pharm Pharmacol , vol.48 , pp. 255-257
    • Guo, J.H.1    Cooklock, K.M.2
  • 81
    • 0033793678 scopus 로고    scopus 로고
    • In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine
    • G. D{stroke}kinci, Y. Çapan, S. Senel, E. Alaaddinoǧlu, T. Dalkara, A. A. Hi{dotless}ncal. In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine. Pharmazie 55:762-65 (2000).
    • (2000) Pharmazie , vol.55 , pp. 762-765
    • Dkinci, G.1    Çapan, Y.2    Senel, S.3    Alaaddinoglu, E.4    Dalkara, T.5    Hincal, A.A.6
  • 82
    • 0142245748 scopus 로고    scopus 로고
    • Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride
    • N. A. Nafee, N. A. Boraie, F. A. Ismail, L. M. Mortada. Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride. Acta Pharm 53:199-212 (2003).
    • (2003) Acta Pharm , vol.53 , pp. 199-212
    • Nafee, N.A.1    Boraie, N.A.2    Ismail, F.A.3    Mortada, L.M.4
  • 83
    • 0037139414 scopus 로고    scopus 로고
    • Effect of chitosan on a periodontal pathogen Porphyromonas gingivalis
    • G. D{stroke}kinci, S. Senel, H. Aki{dotless}nci{dotless}bay, S. Kas, S. Ercis, C. G. Wilson, A. A. Hi{dotless}ncal. Effect of chitosan on a periodontal pathogen Porphyromonas gingivalis. Int J Pharm 235:121-27 (2002).
    • (2002) Int J Pharm , vol.235 , pp. 121-127
    • Dkinci, G.1    Senel, S.2    Akincibay, H.3    Kas, S.4    Ercis, S.5    Wilson, C.G.6    Hincal, A.A.7
  • 84
    • 0035232922 scopus 로고    scopus 로고
    • Subgingival utilization of a 1 % chlorhexidine collagen gel for the treatment of periodontal pockets. A clinical and microbiological study
    • A. H. C. Vinholis, L. C. de Figueiredo, E. Marcantonio Jr, R. A. C. Marcantonio, S. L. S. Salvador, G. Goissis. Subgingival utilization of a 1 % chlorhexidine collagen gel for the treatment of periodontal pockets. A clinical and microbiological study. Braz Dent J 12:209-13 (2001).
    • (2001) Braz Dent J , vol.12 , pp. 209-213
    • Vinholis, A.H.C.1    de Figueiredo, L.C.2    Marcantonio Jr., E.3    Marcantonio, R.A.C.4    Salvador, S.L.S.5    Goissis, G.6
  • 85
    • 0030913693 scopus 로고    scopus 로고
    • Textural analysis and flow rheometry of novel, bioadhesive antimicrobial oral gels
    • D. S. Jones, A. D. Woolfson, A. F. Brown. Textural analysis and flow rheometry of novel, bioadhesive antimicrobial oral gels. Pharm Res 14:450-57 (1997).
    • (1997) Pharm Res , vol.14 , pp. 450-457
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3
  • 86
    • 0033812427 scopus 로고    scopus 로고
    • Examination of the physical state of chlorhexidine within viscoelastic, bioadhesive semisolids using raman spectroscopy
    • D. S. Jones, A. F. Brown, A. D. Woolfson, A. C. Dennis, L. J. Matchett, S. E. J. Bell. Examination of the physical state of chlorhexidine within viscoelastic, bioadhesive semisolids using raman spectroscopy. J Pharm Sci 89:563-71 (2000).
    • (2000) J Pharm Sci , vol.89 , pp. 563-571
    • Jones, D.S.1    Brown, A.F.2    Woolfson, A.D.3    Dennis, A.C.4    Matchett, L.J.5    Bell, S.E.J.6
  • 87
    • 0036191263 scopus 로고    scopus 로고
    • Formulation and in vivo evaluation of chlorhexidine buccal tablets prepared using drug-loaded chitosan microspheres
    • P. Giunchedi, C. Juliano, E. Gavini, M. Cossu, M. Sorrenti. Formulation and in vivo evaluation of chlorhexidine buccal tablets prepared using drug-loaded chitosan microspheres. Eur J Pharm Biopharm 53:233-39 (2002).
    • (2002) Eur J Pharm Biopharm , vol.53 , pp. 233-239
    • Giunchedi, P.1    Juliano, C.2    Gavini, E.3    Cossu, M.4    Sorrenti, M.5
  • 88
    • 0028961380 scopus 로고
    • Casting solvent controlled release of chlorhexidine from ethylcellulose films prepared by solvent evaporation
    • D. S. Jones, N. J. Medlicott. Casting solvent controlled release of chlorhexidine from ethylcellulose films prepared by solvent evaporation. Int J Pharm 114:257-61 (1995).
    • (1995) Int J Pharm , vol.114 , pp. 257-261
    • Jones, D.S.1    Medlicott, N.J.2
  • 89
    • 0033989627 scopus 로고    scopus 로고
    • Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery
    • S. Senel, G. D{stroke}kinci, S. Kas, A. Yousefi{dotless}-Rad, M. F. Sargon, A. A. Hi{dotless}ncal. Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery. Int J Pharm 193:197-203 (2000).
    • (2000) Int J Pharm , vol.193 , pp. 197-203
    • Senel, S.1    Dkinci, G.2    Kas, S.3    Yousefi-Rad, A.4    Sargon, M.F.5    Hincal, A.A.6
  • 90
    • 33947114939 scopus 로고    scopus 로고
    • Evaluation of polyoxyethylene homopolymers for buccal bioadhesive drug delivery device formulations
    • D. Tiwari, D. Goldman, R. Sause, P. L. Madan. Evaluation of polyoxyethylene homopolymers for buccal bioadhesive drug delivery device formulations. AAPS PharmSci 1:E13 (1999).
    • (1999) AAPS PharmSci , vol.1
    • Tiwari, D.1    Goldman, D.2    Sause, R.3    Madan, P.L.4
  • 91
    • 0032707123 scopus 로고    scopus 로고
    • In vitro-in vivo evaluation of a controlled release buccal bioadhesive device for oral drug delivery
    • D. Tiwari, D. Goldman, C. Town, R. Sause, P. L. Madan. In vitro-in vivo evaluation of a controlled release buccal bioadhesive device for oral drug delivery. Pharm Res 16:1775-80 (1999).
    • (1999) Pharm Res , vol.16 , pp. 1775-1780
    • Tiwari, D.1    Goldman, D.2    Town, C.3    Sause, R.4    Madan, P.L.5
  • 92
    • 0027458502 scopus 로고
    • Human transbuccal absorption of diclofenac sodium from a prototype hydrogel delivery device
    • J. Cassidy, B. Berner, K. Chan, V. John, S. Toon, B. Holt, M. Rowland. Human transbuccal absorption of diclofenac sodium from a prototype hydrogel delivery device. Pharm Res 10:126-29 (1993).
    • (1993) Pharm Res , vol.10 , pp. 126-129
    • Cassidy, J.1    Berner, B.2    Chan, K.3    John, V.4    Toon, S.5    Holt, B.6    Rowland, M.7
  • 93
    • 0035999871 scopus 로고    scopus 로고
    • Development of controlled-release buccoadhesive hydrophilic matrices of diltiazem hydrochloride: optimization of bioadhesion, dissolution, and diffusion parameters
    • B. Singh, N. Ahuja. Development of controlled-release buccoadhesive hydrophilic matrices of diltiazem hydrochloride: optimization of bioadhesion, dissolution, and diffusion parameters. Drug Dev Ind Pharm 28:431-42 (2002).
    • (2002) Drug Dev Ind Pharm , vol.28 , pp. 431-442
    • Singh, B.1    Ahuja, N.2
  • 94
    • 0028964194 scopus 로고
    • Development of buccal tablets of diltiazem hydrochloride
    • A. Ahuja, M. Dogra, S. P. Agarwal. Development of buccal tablets of diltiazem hydrochloride. Indian J Pharm Sci 57:26-30 (1995).
    • (1995) Indian J Pharm Sci , vol.57 , pp. 26-30
    • Ahuja, A.1    Dogra, M.2    Agarwal, S.P.3
  • 95
    • 26644449945 scopus 로고    scopus 로고
    • Formulation and pharmaceutical properties of mucoadhesive films containing dipotassium glycyrrhizate
    • G. J. Rhee, D. K. Lee, K. H. Sin, C. B. Park. Formulation and pharmaceutical properties of mucoadhesive films containing dipotassium glycyrrhizate. J Korean Pharm Sci 29:127-36 (1999).
    • (1999) J Korean Pharm Sci , vol.29 , pp. 127-136
    • Rhee, G.J.1    Lee, D.K.2    Sin, K.H.3    Park, C.B.4
  • 96
    • 0037093768 scopus 로고    scopus 로고
    • Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea-pigs
    • K. Tsutsumi, Y. Obata, T. Nagai, T. Loftsson, K. Takayama. Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea-pigs. Int J Pharm 238:161-70 (2002).
    • (2002) Int J Pharm , vol.238 , pp. 161-170
    • Tsutsumi, K.1    Obata, Y.2    Nagai, T.3    Loftsson, T.4    Takayama, K.5
  • 97
    • 0034278415 scopus 로고    scopus 로고
    • Microhardness changes in surface enamel after application of bioadhesive fluoride tablets in situ
    • P. Bottenberg, R. Cleymaet, K. Röhrkasten, F. Lampert. Microhardness changes in surface enamel after application of bioadhesive fluoride tablets in situ. Clin. Oral Investig 4:153-156 (2000).
    • (2000) Clin. Oral Investig , vol.4 , pp. 153-156
    • Bottenberg, P.1    Cleymaet, R.2    Röhrkasten, K.3    Lampert, F.4
  • 98
    • 0033989961 scopus 로고    scopus 로고
    • Salivary fluoride concentrations following applications of bioadhesive tablets and mouthrinses
    • N. Vivien-Castioni, R. Gurny, P. Baehni, V. Kaltsatos. Salivary fluoride concentrations following applications of bioadhesive tablets and mouthrinses. Eur J Pharm Biopharm 49:27-33 (2000).
    • (2000) Eur J Pharm Biopharm , vol.49 , pp. 27-33
    • Vivien-Castioni, N.1    Gurny, R.2    Baehni, P.3    Kaltsatos, V.4
  • 99
    • 0033050183 scopus 로고    scopus 로고
    • Physicochemical characterization and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis
    • D. S. Jones, C. R. Irwin, A. D. Woolfson, J. Djokic, V. Adams. Physicochemical characterization and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis. J Pharm Sci 88:592-98 (1999).
    • (1999) J Pharm Sci , vol.88 , pp. 592-598
    • Jones, D.S.1    Irwin, C.R.2    Woolfson, A.D.3    Djokic, J.4    Adams, V.5
  • 101
    • 0029840172 scopus 로고    scopus 로고
    • Potential therapeutic levels of glucagon-like peptide I achived in humans by a buccal tablet
    • M. K. Gutniak, H. Larsson, S. J. Heiber, O. T. Juneskans, J. J. Holst, B. Ahrén. Potential therapeutic levels of glucagon-like peptide I achived in humans by a buccal tablet. Diabetes Care 19:843-48 (1996).
    • (1996) Diabetes Care , vol.19 , pp. 843-848
    • Gutniak, M.K.1    Larsson, H.2    Heiber, S.J.3    Juneskans, O.T.4    Holst, J.J.5    Ahrén, B.6
  • 104
    • 0034828829 scopus 로고    scopus 로고
    • Design and evaluation of buccal adhesive hydrocortisone acetate (HCA) tablets
    • G. C. Ceschel, P. Maffei, S. Lombardi Biogia, C. Ronchi. Design and evaluation of buccal adhesive hydrocortisone acetate (HCA) tablets. Drug Deliv 8:161-71 (2001).
    • (2001) Drug Deliv , vol.8 , pp. 161-171
    • Ceschel, G.C.1    Maffei, P.2    Lombardi Biogia, S.3    Ronchi, C.4
  • 106
    • 0036335017 scopus 로고    scopus 로고
    • Buccoadhesive tablets for insulin delivery: in-vitro and in-vivo studies
    • E. A. Hosny, S. A. Elkheshen, S. I. Saleh. Buccoadhesive tablets for insulin delivery: in-vitro and in-vivo studies. Boll Chim Farm 141:210-17 (2002).
    • (2002) Boll Chim Farm , vol.141 , pp. 210-217
    • Hosny, E.A.1    Elkheshen, S.A.2    Saleh, S.I.3
  • 109
    • 0035856810 scopus 로고    scopus 로고
    • Development of polymer film dosage forms of Lidocaine for buccal administration: I. Penetration rate and release rate
    • H. Okamoto, H. Taguchi, K. Iida, K. Danjo. Development of polymer film dosage forms of Lidocaine for buccal administration: I. Penetration rate and release rate. J Control Release 77:253-60 (2001).
    • (2001) J Control Release , vol.77 , pp. 253-260
    • Okamoto, H.1    Taguchi, H.2    Iida, K.3    Danjo, K.4
  • 110
    • 0036828034 scopus 로고    scopus 로고
    • Development of polymer film dosage forms of Lidocaine for buccal administration: II. Comparison of preparation methods
    • H. Okamoto, T. Nakamori, Y. Arakawa, K. Iida, K. Danjo. Development of polymer film dosage forms of Lidocaine for buccal administration: II. Comparison of preparation methods. J Pharm Sci 91:2424-32 (2002).
    • (2002) J Pharm Sci , vol.91 , pp. 2424-2432
    • Okamoto, H.1    Nakamori, T.2    Arakawa, Y.3    Iida, K.4    Danjo, K.5
  • 111
    • 19244380349 scopus 로고    scopus 로고
    • Effect of carbopol and polyvinylpyrrolidone on the mechanical, rheological, and release properties of bioadhesive polyethylene glycol gels
    • Y. T. F. Tan, K. K. Peh, O. Al-Hanbali. Effect of carbopol and polyvinylpyrrolidone on the mechanical, rheological, and release properties of bioadhesive polyethylene glycol gels. AAPS PharmSciTech 1:E24 (2000).
    • (2000) AAPS PharmSciTech , vol.1
    • Tan, Y.T.F.1    Peh, K.K.2    Al-Hanbali, O.3
  • 112
    • 0024453858 scopus 로고
    • A lignocaine patch for dental analgesia safety and early pharmacology
    • I. M. Brook, G. T. Tucker, E. C. Tuckley, R. N. Boyes. A lignocaine patch for dental analgesia safety and early pharmacology. J Control Release 10:183-88 (1989).
    • (1989) J Control Release , vol.10 , pp. 183-188
    • Brook, I.M.1    Tucker, G.T.2    Tuckley, E.C.3    Boyes, R.N.4
  • 113
    • 26644473559 scopus 로고    scopus 로고
    • Development and evaluation of mucoadhesive buccal tablets of lignocaine hydrochloride
    • N. Parvez, A. Ahuja, R. K. Khar. Development and evaluation of mucoadhesive buccal tablets of lignocaine hydrochloride. Indian J Pharm Sci 64:563-67 (2002).
    • (2002) Indian J Pharm Sci , vol.64 , pp. 563-567
    • Parvez, N.1    Ahuja, A.2    Khar, R.K.3
  • 114
    • 0030317410 scopus 로고    scopus 로고
    • Oramucosal delivery of LHRH: pharmacokinetic studies of controlled and enhanced transmucosal permeation
    • S. Nakane, M. Kakumoto, K. Yukimatsu, Y. W. Chien. Oramucosal delivery of LHRH: pharmacokinetic studies of controlled and enhanced transmucosal permeation. Pharm Dev Technol 1:251-59 (1996).
    • (1996) Pharm Dev Technol , vol.1 , pp. 251-259
    • Nakane, S.1    Kakumoto, M.2    Yukimatsu, K.3    Chien, Y.W.4
  • 116
    • 2642609471 scopus 로고    scopus 로고
    • Evaluation of buccoadhesive metronidazole tablets: microbiological response
    • A. Ahuja, R. K. Khar, R. Chaudhry. Evaluation of buccoadhesive metronidazole tablets: microbiological response. Pharmazie 53:264-67 (1998).
    • (1998) Pharmazie , vol.53 , pp. 264-267
    • Ahuja, A.1    Khar, R.K.2    Chaudhry, R.3
  • 117
    • 1542614043 scopus 로고    scopus 로고
    • Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease
    • L. Perioli, V. Ambrogi, D. Rubini, S. Giovagnoli, M. Ricci, P. Blasi, C. Rossi. Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease. J Control Release 95:521-33 (2004).
    • (2004) J Control Release , vol.95 , pp. 521-533
    • Perioli, L.1    Ambrogi, V.2    Rubini, D.3    Giovagnoli, S.4    Ricci, M.5    Blasi, P.6    Rossi, C.7
  • 118
    • 0037965570 scopus 로고    scopus 로고
    • Preparation and in vitro/in vivo evaluation of the buccal bioadhesive properties of slow release tablets containing miconazole nitrate
    • F. A. Mohammed, H. Khedr. Preparation and in vitro/in vivo evaluation of the buccal bioadhesive properties of slow release tablets containing miconazole nitrate. Drug Dev Ind Pharm 29:321-37 (2003).
    • (2003) Drug Dev Ind Pharm , vol.29 , pp. 321-337
    • Mohammed, F.A.1    Khedr, H.2
  • 119
    • 0026616964 scopus 로고
    • Comparison of salivary miconazole concentrations after administration of a bioadhesive slow-release buccal tablet and an oral gel
    • S. Bouckaert, H. Schautteet, R. A. Lefebvre, J. P. Remon, R. van Clooster. Comparison of salivary miconazole concentrations after administration of a bioadhesive slow-release buccal tablet and an oral gel. Eur J Clin Pharmacol 43:137-40 (1992).
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 137-140
    • Bouckaert, S.1    Schautteet, H.2    Lefebvre, R.A.3    Remon, J.P.4    van Clooster, R.5
  • 120
    • 0027231108 scopus 로고
    • In vitro/in vivo correlation of the bioadhesive properties of a buccal bioadhesive miconazole slow-release tablet
    • S. Bouckaert, R. A. Lefebvre, J. P. Remon. In vitro/in vivo correlation of the bioadhesive properties of a buccal bioadhesive miconazole slow-release tablet. Pharm Res 10:853-56 (1993).
    • (1993) Pharm Res , vol.10 , pp. 853-856
    • Bouckaert, S.1    Lefebvre, R.A.2    Remon, J.P.3
  • 121
    • 0027151811 scopus 로고
    • Influence of the application site on bioadhesion and slow-release characteristics of a bioadhesive buccal slowrelease tablet of miconazole
    • S. Bouckaert, R. A. Lefebvre, F. Colardyn, J. P. Remon. Influence of the application site on bioadhesion and slow-release characteristics of a bioadhesive buccal slowrelease tablet of miconazole. Eur J Clin Pharmacol 44:331-35 (1993).
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 331-335
    • Bouckaert, S.1    Lefebvre, R.A.2    Colardyn, F.3    Remon, J.P.4
  • 122
    • 0027319353 scopus 로고
    • In-vitro bioadhesion of a buccal, miconazole slowrelease tablet
    • S. Bouckaert, J. P. Remon. In-vitro bioadhesion of a buccal, miconazole slowrelease tablet. J Pharm Pharmacol 45:504-07 (1993).
    • (1993) J Pharm Pharmacol , vol.45 , pp. 504-507
    • Bouckaert, S.1    Remon, J.P.2
  • 123
    • 1642499252 scopus 로고    scopus 로고
    • Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis
    • J. Van Roey, M. Haxaire, M. Kamya, I. Lwanga, E. Katabira. Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis. J Acquir Immune Defic Syndr 35:144-50 (2004).
    • (2004) J Acquir Immune Defic Syndr , vol.35 , pp. 144-150
    • Van Roey, J.1    Haxaire, M.2    Kamya, M.3    Lwanga, I.4    Katabira, E.5
  • 125
    • 0028331097 scopus 로고
    • Formulation and in vitro-in vivo evaluation of buccoadhesive morphine sulfate tablets
    • S. Anlar, Y. Çapan, O. Güven, A. Göǧüs, T. Dalkara, A. A. Hi{dotless}ncal. Formulation and in vitro-in vivo evaluation of buccoadhesive morphine sulfate tablets. Pharm Res 11:231-36 (1994).
    • (1994) Pharm Res , vol.11 , pp. 231-236
    • Anlar, S.1    Çapan, Y.2    Güven, O.3    Gögüs, A.4    Dalkara, T.5    Hincal, A.A.6
  • 126
    • 0033044790 scopus 로고    scopus 로고
    • Mucoadhesive buccal disks for novel nalbuphine prodrug controlled delivery: effect of formulation variables on drug release and mucoadhesive performance
    • R. Y. Han, J. Y. Fang, K. C. Sung, O. Y. P. Hu. Mucoadhesive buccal disks for novel nalbuphine prodrug controlled delivery: effect of formulation variables on drug release and mucoadhesive performance. Int J Pharm 177:201-09 (1999).
    • (1999) Int J Pharm , vol.177 , pp. 201-209
    • Han, R.Y.1    Fang, J.Y.2    Sung, K.C.3    Hu, O.Y.P.4
  • 127
    • 0037177497 scopus 로고    scopus 로고
    • Development and evaluation of a biphasic buccal adhesive tablet for nicotine replacement therapy
    • C. R. Park, D. L. Munday. Development and evaluation of a biphasic buccal adhesive tablet for nicotine replacement therapy. Int J Pharm 237:215-26 (2002).
    • (2002) Int J Pharm , vol.237 , pp. 215-226
    • Park, C.R.1    Munday, D.L.2
  • 128
    • 2442705058 scopus 로고    scopus 로고
    • Development of a buccal bioadhesive nicotine tablet formulation for smoking cessation
    • G. D{stroke}kinci, S. Senel, C. G. Wilson, M. Sumnu. Development of a buccal bioadhesive nicotine tablet formulation for smoking cessation. Int J Pharm 277:173-78 (2004).
    • (2004) Int J Pharm , vol.277 , pp. 173-178
    • Dkinci, G.1    Senel, S.2    Wilson, C.G.3    Sumnu, M.4
  • 129
    • 0028209835 scopus 로고
    • Comparative study of buccoadhesive formulations and sublingual capsules of nifedipine
    • T. Save, M. U. Shah, A. R. Ghamande, P. Venkitachalam. Comparative study of buccoadhesive formulations and sublingual capsules of nifedipine. J Pharm Pharmacol 46:192-95 (1994).
    • (1994) J Pharm Pharmacol , vol.46 , pp. 192-195
    • Save, T.1    Shah, M.U.2    Ghamande, A.R.3    Venkitachalam, P.4
  • 130
    • 0037712690 scopus 로고    scopus 로고
    • Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery
    • C. Remuñán-López, A. Portero, J. L. Vila-Jato, M. J. Alonso. Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery. J Control Release 55:143-52 (1998).
    • (1998) J Control Release , vol.55 , pp. 143-152
    • Remuñán-López, C.1    Portero, A.2    Vila-Jato, J.L.3    Alonso, M.J.4
  • 131
    • 0027319353 scopus 로고
    • In-vitro bioadhesion of a buccal, miconazole slowrelease tablet
    • S. Bouckaert, J. P. Remon. In-vitro bioadhesion of a buccal, miconazole slowrelease tablet. J Pharm Pharmacol 45:504-07 (1993).
    • (1993) J Pharm Pharmacol , vol.45 , pp. 504-507
    • Bouckaert, S.1    Remon, J.P.2
  • 133
    • 0034601667 scopus 로고    scopus 로고
    • Development of omeprazole buccal adhesive tablets with stability enhancement in human saliva
    • H. G. Choi, C. K. Kim. Development of omeprazole buccal adhesive tablets with stability enhancement in human saliva. J Control Release 68:397-404 (2000).
    • (2000) J Control Release , vol.68 , pp. 397-404
    • Choi, H.G.1    Kim, C.K.2
  • 134
    • 0030317029 scopus 로고    scopus 로고
    • In vitro release and permeation of oxytocin from a mucoadhesive buccal patch
    • C. Li, P. P. Bhatt, T. P. Johnston. In vitro release and permeation of oxytocin from a mucoadhesive buccal patch. Pharm Dev Technol 1:357-64 (1996).
    • (1996) Pharm Dev Technol , vol.1 , pp. 357-364
    • Li, C.1    Bhatt, P.P.2    Johnston, T.P.3
  • 135
    • 0031392482 scopus 로고    scopus 로고
    • Transmucosal delivery of oxytocin to rabbits using a mucoadhesive buccal patch
    • C. Li, P. P. Bhatt, T. P. Johnston. Transmucosal delivery of oxytocin to rabbits using a mucoadhesive buccal patch. Pharm Dev Technol 2:265-74 (1997).
    • (1997) Pharm Dev Technol , vol.2 , pp. 265-274
    • Li, C.1    Bhatt, P.P.2    Johnston, T.P.3
  • 136
    • 0032942220 scopus 로고    scopus 로고
    • Design, development, and biopharmaceutical properties of buccoadhesive compacts of pentazocine
    • V. Agarwal, B. Mishra. Design, development, and biopharmaceutical properties of buccoadhesive compacts of pentazocine. Drug Dev Ind Pharm 25:701-09 (1999).
    • (1999) Drug Dev Ind Pharm , vol.25 , pp. 701-709
    • Agarwal, V.1    Mishra, B.2
  • 137
    • 0345337285 scopus 로고    scopus 로고
    • Development and in vitro evaluation of a buccoadhesive pindolol tablet formulation
    • B. Dortunç, L. Özer, N. Uyanik. Development and in vitro evaluation of a buccoadhesive pindolol tablet formulation. Drug Dev Ind Pharm 24:281-88 (1998).
    • (1998) Drug Dev Ind Pharm , vol.24 , pp. 281-288
    • Dortunç, B.1    Özer, L.2    Uyanik, N.3
  • 138
    • 0742287066 scopus 로고    scopus 로고
    • Influence of hydroxypropyl-b-cyclodextrin complexation on piroxicam release from buccoadhesive tablets
    • M. Jug, M. Bećirević-Laćan. Influence of hydroxypropyl-β-cyclodextrin complexation on piroxicam release from buccoadhesive tablets. Eur J Pharm Sci 21:251-60 (2004).
    • (2004) Eur J Pharm Sci , vol.21 , pp. 251-260
    • Jug, M.1    Becirevic-Lacan, M.2
  • 139
    • 0036863206 scopus 로고    scopus 로고
    • In vitro permeation through porcine buccal mucosa of caffeic acid phenetyl ester (CAPE) from a topical mucoadhesive gel containing propolis
    • G. C. Ceschel, P. Maffei, A. Sforzini, S. Lombardi Borgia, A. Yasin, C. Ronchi. In vitro permeation through porcine buccal mucosa of caffeic acid phenetyl ester (CAPE) from a topical mucoadhesive gel containing propolis. Fitoterapia 73(1):S44-52 (2002).
    • (2002) Fitoterapia , vol.73 , Issue.1
    • Ceschel, G.C.1    Maffei, P.2    Sforzini, A.3    Lombardi Borgia, S.4    Yasin, A.5    Ronchi, C.6
  • 140
    • 0029044411 scopus 로고
    • Development and evaluation of a buccoadhesive propranolol tablet formulation
    • N. Çelebi, O. Kislal. Development and evaluation of a buccoadhesive propranolol tablet formulation. Pharmazie 50:470-72 (1995).
    • (1995) Pharmazie , vol.50 , pp. 470-472
    • Çelebi, N.1    Kislal, O.2
  • 141
    • 1042302115 scopus 로고    scopus 로고
    • Development and evaluation of buccoadhesive propranolol hydrochloride tablet formulations: effect of fillers
    • J. Akbari, A. Nokhodchi, D. Farid, M. Adrangui, M. R. Siahi-Shadbad, M. Saeedi. Development and evaluation of buccoadhesive propranolol hydrochloride tablet formulations: effect of fillers. IL Farmaco 59:155-61 (2004).
    • (2004) IL Farmaco , vol.59 , pp. 155-161
    • Akbari, J.1    Nokhodchi, A.2    Farid, D.3    Adrangui, M.4    Siahi-Shadbad, M.R.5    Saeedi, M.6
  • 143
    • 2342539202 scopus 로고    scopus 로고
    • Buccal mucosal ulcer healing effect of rhEGF/Eudispert hv hydrogel
    • J. S. Park, J. I. Yoon, H. Li, D. C. Moon, K. Han. Buccal mucosal ulcer healing effect of rhEGF/Eudispert hv hydrogel. Arch Pharm Res 26:659-65 (2003).
    • (2003) Arch Pharm Res , vol.26 , pp. 659-665
    • Park, J.S.1    Yoon, J.I.2    Li, H.3    Moon, D.C.4    Han, K.5
  • 144
    • 0036913714 scopus 로고    scopus 로고
    • Buccal transmucosal delivery of calcitonin in rabbits using thinfilm composites
    • Z. Cui, R. J. Mumper. Buccal transmucosal delivery of calcitonin in rabbits using thinfilm composites. Pharm Res 19:1901-06 (2002).
    • (2002) Pharm Res , vol.19 , pp. 1901-1906
    • Cui, Z.1    Mumper, R.J.2
  • 145
    • 0032732323 scopus 로고    scopus 로고
    • Evaluation of a novel, natural oligosaccharide gum as a sustainedrelease and mucoadhesive component of calcitonin buccal tablets
    • H. H. Alur, J. D. Beal, S. I. Pather, A. K. Mitra, T. P. Johnston. Evaluation of a novel, natural oligosaccharide gum as a sustainedrelease and mucoadhesive component of calcitonin buccal tablets. J Pharm Sci 88:1313-19 (1999).
    • (1999) J Pharm Sci , vol.88 , pp. 1313-1319
    • Alur, H.H.1    Beal, J.D.2    Pather, S.I.3    Mitra, A.K.4    Johnston, T.P.5
  • 146
    • 0037341092 scopus 로고    scopus 로고
    • Fluoride controlled release tablets for intrabuccal use
    • M. Diarra, G. Pourroy, C. Boymond, D. Muster. Fluoride controlled release tablets for intrabuccal use. Biomaterials 24:1293-1300 (2003).
    • (2003) Biomaterials , vol.24 , pp. 1293-1300
    • Diarra, M.1    Pourroy, G.2    Boymond, C.3    Muster, D.4
  • 147
    • 26644460782 scopus 로고    scopus 로고
    • Development and characterization of a buccoadhesive dosage form of terbutaline sulphate
    • M. I. Mohamed, N. D. Mortada. Development and characterization of a buccoadhesive dosage form of terbutaline sulphate. Mansoura J Pharm Sci 16:69-81 (2000).
    • (2000) Mansoura J Pharm Sci , vol.16 , pp. 69-81
    • Mohamed, M.I.1    Mortada, N.D.2
  • 148
    • 0037133130 scopus 로고    scopus 로고
    • Ex vivo bioadhesion and in vivo testosterone bioavailability study of different bioadhesive formulations based on starch-g-poly(acrylic acid) copolymers and starch/poly(acrylic acid) mixtures
    • D. Ameye, J. Voorspoels, P. Foreman, J. Tsai, P. Richardson, S. Geresh, J. P. Remon. Ex vivo bioadhesion and in vivo testosterone bioavailability study of different bioadhesive formulations based on starch-g-poly(acrylic acid) copolymers and starch/poly(acrylic acid) mixtures. J Control Release 79:173-82 (2002).
    • (2002) J Control Release , vol.79 , pp. 173-182
    • Ameye, D.1    Voorspoels, J.2    Foreman, P.3    Tsai, J.4    Richardson, P.5    Geresh, S.6    Remon, J.P.7
  • 149
    • 0029781954 scopus 로고    scopus 로고
    • Buccal absorption of testosterone and its esters using a bioadhesive tablet in dogs
    • J. Voorspoels, J. P. Remon, W. Eechaute, W. Sy De. Buccal absorption of testosterone and its esters using a bioadhesive tablet in dogs. Pharm Res 13:1228-32 (1996).
    • (1996) Pharm Res , vol.13 , pp. 1228-1232
    • Voorspoels, J.1    Remon, J.P.2    Eechaute, W.3    Sy De, W.4
  • 151
    • 0036771443 scopus 로고    scopus 로고
    • Transmucosal delivery of testosterone in rabbits using novel bi-layer mucoadhesive wax-film composite disks
    • S. Jay, W. Fountain, Z. Cui, R. J. Mumper. Transmucosal delivery of testosterone in rabbits using novel bi-layer mucoadhesive wax-film composite disks. J Pharm Sci 91:2016-25 (2002).
    • (2002) J Pharm Sci , vol.91 , pp. 2016-2025
    • Jay, S.1    Fountain, W.2    Cui, Z.3    Mumper, R.J.4
  • 152
    • 0024797071 scopus 로고
    • Subgingival administration of tetracycline on a collagen film
    • M. Minabe, K. Takeuchi, T. Tamura, T. Hori, T. Umemoto. Subgingival administration of tetracycline on a collagen film. J Periodontol 60:552-56 (1989).
    • (1989) J Periodontol , vol.60 , pp. 552-556
    • Minabe, M.1    Takeuchi, K.2    Tamura, T.3    Hori, T.4    Umemoto, T.5
  • 153
    • 0034601173 scopus 로고    scopus 로고
    • Design, characterization and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease
    • D. S. Jones, A. D. Woolfson, A. F. Brown, W. A. Coulter, C. McClelland, C. R. Irwin. Design, characterization and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease. J Control Release 67:357-68 (2000).
    • (2000) J Control Release , vol.67 , pp. 357-368
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3    Coulter, W.A.4    McClelland, C.5    Irwin, C.R.6
  • 154
    • 0030469411 scopus 로고    scopus 로고
    • Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases
    • D. S. Jones, A. D. Woolfson, J. Djokic, W. A. Coulter. Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases. Pharm Res 13:1734-38 (1996).
    • (1996) Pharm Res , vol.13 , pp. 1734-1738
    • Jones, D.S.1    Woolfson, A.D.2    Djokic, J.3    Coulter, W.A.4
  • 155
    • 1642482825 scopus 로고    scopus 로고
    • Bioadhesive grafted starch copolymers as platforms for peroral drug delivery: a study of theophylline release
    • S. Geresh, G. Y. Gdalevsky, I. Gilboa, J. Voorspoels, J. P. Remon, J. Kost. Bioadhesive grafted starch copolymers as platforms for peroral drug delivery: a study of theophylline release. J Control Release 94:391-99 (2004).
    • (2004) J Control Release , vol.94 , pp. 391-399
    • Geresh, S.1    Gdalevsky, G.Y.2    Gilboa, I.3    Voorspoels, J.4    Remon, J.P.5    Kost, J.6
  • 156
    • 0037413398 scopus 로고    scopus 로고
    • Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies
    • M. Artusi, P. Santi, P. Colombo, H. E. Junginger. Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies. Int J Pharm 250:203-13 (2003).
    • (2003) Int J Pharm , vol.250 , pp. 203-213
    • Artusi, M.1    Santi, P.2    Colombo, P.3    Junginger, H.E.4
  • 157
    • 0030906544 scopus 로고    scopus 로고
    • Absorption of thyrotropinreleasing hormone in rats using a mucoadhesive buccal patch
    • C. Li, R. L. Koch, V. A. Raul, P. P. Bhatt, T. P. Johnston. Absorption of thyrotropinreleasing hormone in rats using a mucoadhesive buccal patch. Drug Dev Ind Pharm 23:239-46 (1997).
    • (1997) Drug Dev Ind Pharm , vol.23 , pp. 239-246
    • Li, C.1    Koch, R.L.2    Raul, V.A.3    Bhatt, P.P.4    Johnston, T.P.5
  • 158
    • 0021888192 scopus 로고
    • Comparative study of intravenous, nasal, oral and buccal TRH administration among healthy subjects
    • W. Schurr, B. Knoll, R. Ziegler, R. Anders, H. P. Merkle. Comparative study of intravenous, nasal, oral and buccal TRH administration among healthy subjects. J Endocrinol Invest 8:41-4 (1985).
    • (1985) J Endocrinol Invest , vol.8 , pp. 41-44
    • Schurr, W.1    Knoll, B.2    Ziegler, R.3    Anders, R.4    Merkle, H.P.5
  • 159
    • 0034308327 scopus 로고    scopus 로고
    • Enhancing effect of chitosan on peptide drug delivery across buccal mucosa
    • S. Senel, M. J. Kremer, S. Kas, P. W. Wertz, A. A. Hi{dotless}ncal, C. A. Squier. Enhancing effect of chitosan on peptide drug delivery across buccal mucosa. Biomaterials 21:2067-71 (2000).
    • (2000) Biomaterials , vol.21 , pp. 2067-2071
    • Senel, S.1    Kremer, M.J.2    Kas, S.3    Wertz, P.W.4    Hincal, A.A.5    Squier, C.A.6
  • 160
    • 0034687581 scopus 로고    scopus 로고
    • Enhanced bioavailability by buccal administration of triamcinolone acetonide from the bioadhesive gels in rabbits
    • S. C. Shin, J. P. Bum, J. S. Choi. Enhanced bioavailability by buccal administration of triamcinolone acetonide from the bioadhesive gels in rabbits. Int J Pharm 209:37-43 (2000).
    • (2000) Int J Pharm , vol.209 , pp. 37-43
    • Shin, S.C.1    Bum, J.P.2    Choi, J.S.3
  • 161
    • 0033844540 scopus 로고    scopus 로고
    • Enhanced permeation of triamcinolone acetonide through the buccal mucosa
    • S. C. Shin, J. Y. Kim. Enhanced permeation of triamcinolone acetonide through the buccal mucosa. Eur J Pharm Biopharm 50:217-20 (2000).
    • (2000) Eur J Pharm Biopharm , vol.50 , pp. 217-220
    • Shin, S.C.1    Kim, J.Y.2
  • 162
    • 0032142835 scopus 로고    scopus 로고
    • Elaboration and evaluation of an intraoral controlled release delivering system
    • M. Diarra, G. Pourroy, D. Muster, M. Zingraff, C. Boymond. Elaboration and evaluation of an intraoral controlled release delivering system. Biomaterials 19:1523-27 (1998).
    • (1998) Biomaterials , vol.19 , pp. 1523-1527
    • Diarra, M.1    Pourroy, G.2    Muster, D.3    Zingraff, M.4    Boymond, C.5
  • 163
    • 2942598050 scopus 로고    scopus 로고
    • Mucoadhesion dependence of pharmaceutical polymers on mucosa characteristics
    • D. Accili, G. Menghi, G. Bonacucina, P. Martino, G. Palmieri. Mucoadhesion dependence of pharmaceutical polymers on mucosa characteristics. Eur J Pharm Sci 22:225-34 (2004).
    • (2004) Eur J Pharm Sci , vol.22 , pp. 225-234
    • Accili, D.1    Menghi, G.2    Bonacucina, G.3    Martino, P.4    Palmieri, G.5
  • 164
    • 0022455860 scopus 로고
    • Systems for controlled release of drugs. V: Bioadhesive systems
    • A. G. Mikos, N. A. Peppas. Systems for controlled release of drugs. V: Bioadhesive systems. STP Pharma Sci 19:705-15 (1986).
    • (1986) STP Pharma Sci , vol.19 , pp. 705-715
    • Mikos, A.G.1    Peppas, N.A.2
  • 165
    • 0021236615 scopus 로고
    • An in-vitro investigation of mucosa-adhesive materials for use in controlled drug delivery
    • J. D. Smart, I. W. Kellaway, H. E. Worthington. An in-vitro investigation of mucosa-adhesive materials for use in controlled drug delivery. J Pharm Pharmacol 36:295-99 (1984).
    • (1984) J Pharm Pharmacol , vol.36 , pp. 295-299
    • Smart, J.D.1    Kellaway, I.W.2    Worthington, H.E.3
  • 166
    • 0033002498 scopus 로고    scopus 로고
    • An in-vitro method for buccal adhesion studies: importance of instrument variables
    • C. Wong, K. Yuen, K. Peh. An in-vitro method for buccal adhesion studies: importance of instrument variables. Int J Pharm 180:47-57 (1999).
    • (1999) Int J Pharm , vol.180 , pp. 47-57
    • Wong, C.1    Yuen, K.2    Peh, K.3
  • 167
    • 0023856674 scopus 로고
    • The contribution of anionic polymer structural features to mucoadhesion
    • S. H. Leung, J. R. Robinson. The contribution of anionic polymer structural features to mucoadhesion. J Control Release 5:223-31 (1988).
    • (1988) J Control Release , vol.5 , pp. 223-231
    • Leung, S.H.1    Robinson, J.R.2
  • 168
    • 0028896195 scopus 로고
    • An investigation of some factors influencing the in vitro assessment of mucoadhesion
    • S. A. Mortazavi, J. D. Smart. An investigation of some factors influencing the in vitro assessment of mucoadhesion. Int J Pharm 116:223-30 (1995).
    • (1995) Int J Pharm , vol.116 , pp. 223-230
    • Mortazavi, S.A.1    Smart, J.D.2
  • 169
    • 0035901695 scopus 로고    scopus 로고
    • An investigation of mucus/polymer rheological synergism using synthesized and characterized poly(acrylic acid)s
    • R. Riley, J. Smart, J. Tsibouklis, P. Dettmar, F. Hampson, J. A. Davis, G. Kelly, W. Wilber. An investigation of mucus/polymer rheological synergism using synthesized and characterized poly(acrylic acid)s. Int J Pharm 217:87-100 (2001).
    • (2001) Int J Pharm , vol.217 , pp. 87-100
    • Riley, R.1    Smart, J.2    Tsibouklis, J.3    Dettmar, P.4    Hampson, F.5    Davis, J.A.6    Kelly, G.7    Wilber, W.8
  • 170
    • 0025108791 scopus 로고
    • A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength
    • E. E. Hassan, J. M. Gallo. A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength. Pharm Res 7:491-95 (1990).
    • (1990) Pharm Res , vol.7 , pp. 491-495
    • Hassan, E.E.1    Gallo, J.M.2
  • 171
    • 0021344079 scopus 로고
    • Bioadhesive polymers as platforms for oral-controlled drug delivery: method to study bioadhesion
    • K. Park, J. R. Robinson. Bioadhesive polymers as platforms for oral-controlled drug delivery: method to study bioadhesion. Int J Pharm 19:107-127 (1984).
    • (1984) Int J Pharm , vol.19 , pp. 107-127
    • Park, K.1    Robinson, J.R.2
  • 172
    • 26644447977 scopus 로고    scopus 로고
    • Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems
    • H. Takeuchi, J. Thongborisute, Y. Matsui, H. Sugihara, H. Yamamoto, Y. Kawashima. Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems. Adv Drug Deliv Rev 57:1583-94 (2005).
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1583-1594
    • Takeuchi, H.1    Thongborisute, J.2    Matsui, Y.3    Sugihara, H.4    Yamamoto, H.5    Kawashima, Y.6


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