Examination of the physical state of chlorhexidine within viscoelastic, bioadhesive semisolids using Raman spectroscopy

Journal of Pharmaceutical Sciences

Volumn 89, Issue 5, 2000, Pages 563-571

  Jones, David S ^a   Brown, Andrew F ^a   Woolfson, A David ^a   Dennis, Andrew C ^a   Matchett, Lindsey J ^a   Bell, Steven E J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORHEXIDINE;

ARTICLE; CHEMICAL ANALYSIS; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STRUCTURE; HYDROGEN BOND; IONIZATION; PARTICLE SIZE; PROTON TRANSPORT; RAMAN SPECTROMETRY; SOLUBILIZATION; VISCOELASTICITY;

EID: 0033812427     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6017(200005)89:5<563::AID-JPS1>3.0.CO;2-Q     Document Type: Article

References (10)

1. Local delivery of antimicrobial agents to the oral cavity
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3. Viscoelastic properties of bioadhesive, antimicrobial oral gels
4. In vitro/in vivo performance of bioadhesive, tetracycline-containing semi-solids for the treatment of periodontal diseases
5. Raman spectroscopy and polymer analysis
6. Fourier transform Raman spectroscopy of polymeric biomaterials and drug delivery systems
7. The application of Fourier transform Raman spectroscopy to the analysis of pharmaceuticals and biomaterials
8. Texture profile analysis of bioadhesive, polymeric semisolids: Mechanical characterisation and investigation of interactions between formulation components
9. Oral cavity as a site for bioadhesive drug delivery