In vitro fermentation by human gut bacteria of proteolytically digested caseinomacropeptide nonenzymatically glycosylated with prebiotic carbohydrates

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 22, 2011, Pages 11949-11955

  Hernandez Hernandez, Oswaldo ^a   Sanz, M Luz ^a   Kolida, Sofia ^b   Rastall, Robert A ^b   Moreno, F Javier ^c  

^a INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^b UNIVERSITY OF READING   (United Kingdom)

^c UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Amadori compound; bifidogenic; caseinomacropeptide; galacto oligosaccharides; lactulose; Maillard reaction; prebiotics

Indexed keywords

AMADORI COMPOUND; BIFIDOGENIC; CASEINOMACROPEPTIDE; GALACTO-OLIGOSACCHARIDES; LACTULOSE; MAILLARD REACTION; PREBIOTICS;

BATCH CELL CULTURE; CARBOHYDRATES; CLOSTRIDIUM; FATTY ACIDS; GLYCOSYLATION; LACTIC ACID; OLIGOSACCHARIDES;

FERMENTATION;

CARBOHYDRATE; CASEIN; CASEINOMACROPEPTIDE; PEPTIDE FRAGMENT; PREBIOTIC AGENT;

ADULT; ARTICLE; BACTERIUM; CARBOHYDRATE METABOLISM; CHEMISTRY; FECES; FEMALE; FERMENTATION; GASTROINTESTINAL TRACT; GLYCOSYLATION; HUMAN; HYDROLYSIS; ISOLATION AND PURIFICATION; MALE; METABOLISM; MICROBIOLOGY;

ADULT; BACTERIA; CARBOHYDRATE METABOLISM; CARBOHYDRATES; CASEINS; FECES; FEMALE; FERMENTATION; GASTROINTESTINAL TRACT; GLYCOSYLATION; HUMANS; HYDROLYSIS; MALE; PEPTIDE FRAGMENTS; PREBIOTICS;

ATOPOBIUM; BACTERIA (MICROORGANISMS); BACTEROIDES; CLOSTRIDIUM; CLOSTRIDIUM COCCOIDES; CLOSTRIDIUM HISTOLYTICUM; ENTEROCOCCUS; EUBACTERIUM RECTALE; LACTOBACILLUS;

EID: 81255143223     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf203576g     Document Type: Article

References (46)

1. Delfour, A.; Jolles, J.; Alais, C.; Jolles, P. Caseino-glycopeptides: characterization of a methionin residue and of the N-terminal sequence Biochem. Biophys. Res. Commun. 1965, 19, 452-455
2. Manso, M. A.; Lopez-Fandino, R. Angiotensin I converting enzyme-inhibitory activity of bovine, ovine, and caprine κ-casein macropeptides and their tryptic hydrolysates J. Food Prot. 2004, 66, 1686-1692 (Pubitemid 37135069)
3. Recio, I.; Moreno, F. J.; Lopez-Fandino, R. Glycosylated dairy components: their roles in nature and ways to make use of their biofunctionality in dairy products. In Dairy-Derived Ingredients: Food and Nutraceutical Uses; Corredig, M., Ed.; Woodhead Publishing: Cambridge, U.K., 2009; pp 170-211.
4. Stromqvist, M.; Falk, P.; Bergstrom, S.; Hansson, L.; Lonnerdal, B.; Normark, S.; Hernell, O. Human-milk k-casein and inhibition of Helicobacter pylori adhesion to human gastric-mucosa J. Pediatr. Gastroenterol. Nutr. 1995, 21, 288-296
5. Dziuba, J.; Minkiewicz, P. Influence of glycosylation on micelle-stabilizing ability and biological properties of C-terminal fragments of cows κ-casein Int. Dairy J. 1996, 6, 1017-1044 (Pubitemid 27295328)
6. Azuma, N.; Yamauchi, K.; Mitsuoka, T. Bifidus growth-promoting activity of a glycomacropeptide derived from human κ-casein Agric. Biol. Chem. 1984, 48, 2159-2162 (Pubitemid 14010651)
7. Idota, T.; Kawakami, H.; Nakajima, I. Bifidus growth-promoting activity effect of N -acetylneuraminic acid-containing substances Biosci., Biotechnol., Biochem. 1994, 58, 1720-1722
8. Janer, C.; Pelaez, C.; Requena, T. Caseinomacropeptide and whey protein concentrate enhance Bifidobacterium lactis growth in milk Food Chem. 2004, 86, 263-267 (Pubitemid 38292197)
9. Brück, W. M.; Graverholt, G.; Gibson, G. R. Use of batch culture and a two-stage continuous culture system to study the effect of supplemental α-lactalbumin and glycomacropeptide on mixed populations of human gut bacteria FEMS Microbiol. Ecol. 2002, 41, 231-237
10. Brück, W. M.; Redgrave, M.; Tuohy, K. M.; Lönnerdal, B.; Graverholt, G.; Hernell, O.; Gibson, G. R. Effects of bovine α-lactalbumin and casein glycomacropeptide enriched infant formulae on fecal microbiota in healthy term infants J. Pediatr. Gastroenterol. Nutr. 2006, 43, 673-679 (Pubitemid 44863697)
11. Oliver, C. M.; Melton, L. D.; Stanley, R. A. Creating proteins with novel functionality via the Maillard reaction: a review Crit. Rev. Food Sci. Nutr. 2006, 46, 337-350
12. Ames, J. M.; Wynne, A.; Hofmann, A.; Plos, S.; Gibson, G. R. The effect of a model melanoidin mixture on faecal bacterial populations in vitro Br. J. Nutr. 1999, 82, 489-495
13. Borrelli, R. C.; Fogliano, V. Bread crust melanoidins as potential prebiotic ingredients Mol. Nutr. Food Res. 2005, 49, 673-678 (Pubitemid 41008204)
14. Tuohy, K. M.; Hinton, D. J. S.; Davies, S. J.; Crabbe, M. J. C.; Gibson, G. R.; Ames, J. M. Metabolism of Maillard reaction products by the human gut microbiota - implications for health Mol. Nutr. Food Res. 2006, 50, 847-857 (Pubitemid 44433097)
15. Summa, C.; McCourt, J.; Cämmerer, B.; Fiala, A.; Probst, M.; Kun, S.; Anklam, E.; Wagner, K.-H. Radical scavenging activity, anti-bacterial and mutagenic effects of cocoa bean Maillard reaction products with degree of roasting Mol. Nutr. Food Res. 2008, 52, 342-351
16. Huebner, J.; Wehling, R.; Parkhurst, A.; Hutkins, R. Effect of processing conditions on the prebiotic activity of commercial prebiotics Int. Dairy J. 2008, 18, 287-293 (Pubitemid 350166920)
17. Erbersdobler, H. F.; Faist, V. Metabolic transit of Amadori products Nahrung 2001, 45, 177-181 (Pubitemid 33626929)
18. Faist, V.; Erbersdobler, H. F. Metabolic transit and in vivo effects of melanoidins and precursor compounds deriving from the Maillard reaction Ann. Nutr. Metab. 2001, 45, 1-12 (Pubitemid 32221196)
19. Finot, P. A. The absorption and metabolism of modified amino acids in processed foods J. AOAC Int. 2005, 88, 894-903
20. Gibson, G. R.; Probert, H. M.; Loo, J. V.; Rastall, R. A.; Roberfroid, M. B. Dietary modulation of the human colonic microbiota: updating the concept of prebiotics Nutr. Res. Rev. 2004, 17, 259-275
21. Hernández, O.; Ruiz-Matute, A. I.; Olano, A.; Moreno, F. J.; Sanz, M. L. Comparison of fractionation techniques to obtain prebiotic galactooligosaccharides Int. Dairy J. 2009, 19, 531-536
22. Clemente, A.; Rubio, L. A.; Sanz, Y.; Laparra, J. M.; Sanz, M. L.; Hernández, O. J.; Montilla, A.; Olano, A.; Moreno, F. J. Multi-functional galacto-oligosaccharides derived from lactulose with immunomodulatory and prebiotic activities. Spanish Patent P201130784, 2011.
23. Morales, V.; Sanz, M. L.; Olano, A.; Corzo, N. Rapid separation on activated charcoal of high oligosaccharides in honey Chromatographia 2006, 64, 1-6
24. Hernández-Hernández, O.; Lebrón-Aguilar, R.; Quintanilla-López, J. E.; Sanz, M. L.; Moreno, F. J. Development of a new method using hydrophilic interaction liquid chromatography (HILIC)-tandem mass spectrometry for the characterization of O -sialoglycopeptides from proteolytically digested caseinomacropeptide Proteomics 2010, 10, 3699-3711
25. Moreno, F. J.; Lopez-Fandino, R.; Olano, A. Characterization and functional properties of lactosyl caseinmacropeptide conjugates J. Agric. Food Chem. 2002, 50, 5179-5184 (Pubitemid 34925109)
26. Resmini, P.; Pellegrino, L.; Batelli, G. Accurate quantification of furosine in milk and dairy products by a direct HPLC method Ital. J. Food Sci. 1990, 2, 173-183
27. Sanz, M.; Sanz, J.; Martinez-Castro, I. Gas chromatographic-mass spectrometric method for the qualitative and quantitative determination of disaccharides and trisaccharides in honey J. Chromatogr., A 2004, 1059, 143-148 (Pubitemid 39539772)
28. Martin-Pelaez, S.; Gibson, G. R.; Martin-Orue, S. M.; Klinder, A.; Rastall, R. A.; La Ragione, R. M.; Woodward, M. J.; Costabile, A. In vitro fermentation of carbohydrates by porcine faecal inocula and their influence on Salmonella typhimurium growth in batch culture systems FEMS Microbiol. Ecol. 2008, 66, 608-619
29. Langendijk, P. S.; Schut, F.; Jansen, G. J.; Raangs, G. C.; Kamphuis, G. R.; Wilkinson, M. H. F.; Welling, G. W. Quantitative fluorescence in-situ hybridization of Bifidobacterium spp with genus-specific 16S ribosomal-RNA-targeted probes and its application in fecal samples Appl. Environ. Microbiol. 1995, 61, 3069-3075
30. Manz, W.; Amann, R.; Ludwig, W.; Vancanneyt, M.; Schleifer, K. H. Application of a suite of 16S rRNA-specific oligonucleotide probes designed to investigate bacteria of the phylum cytophaga-flavobacter-bacteroides in the natural environment Microbiology 1996, 142, 1097-1106 (Pubitemid 26154919)
31. Franks, A. H.; Harmsen, H. J. M.; Raangs, G. C.; Jansen, G. J.; Schut, F.; Welling, G. W. Variations of bacterial populations in human feces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes Appl. Environ. Microbiol. 1998, 64, 3336-3345 (Pubitemid 28411456)
32. Harmsen, H. J. M.; Elfferich, P.; Schut, F.; Welling, G. W. A 16S rRNA-targeted probe for detection of Lactobacilli and Enterococci in faecal samples by fluorescent in situ hybridization Microb. Ecol. Health Dis. 1999, 11, 3-12 (Pubitemid 29248950)
33. Sanz, M.; Gibson, G. R.; Rastall, R. A. Influence of disaccharide structure on prebiotic selectivity in vitro J. Agric. Food Chem. 2005, 53, 5192-5199 (Pubitemid 40994825)
34. Bunn, H. F.; Higgins, P. J. Reactions of monosaccharides with proteins: possible evolutionary significance Science 1981, 213, 222-224 (Pubitemid 11060569)
35. Otieno, D. O. Synthesis of β-galactooligosaccharides from lactose using microbial β-galactosidases Compr. Rev. Food Sci. Food Saf. 2010, 9, 471-482
36. Martinez-Villaluenga, C.; Cardelle-Cobas, A.; Olano, A.; Corzo, N.; Villamiel, M.; Jimeno, M. L. Enzymatic synthesis and identification of two trisaccharides produced from lactulose by transgalactosylation J. Agric. Food Chem. 2008, 56, 557-563 (Pubitemid 351212585)
37. Chevalier, F.; Chobert, J. M.; Molle, D.; Haertlé, T. Maillard glycation of β-lactoglobulin with several sugars: comparative study of the properties of the obtained polymers and of the substituted sites Lait 2001, 81, 651-666
38. Corzo-Martínez, M.; Moreno, F. J.; Villamiel, M.; Harte, F. M. Characterization and improvement of rheological properties of sodium caseinate glycated with galactose, lactose and dextran Food Hydrocolloids 2010, 24, 88-97
39. Benson, K. A.; Kelly, S. A.; Legge, R.; Ma, F.; Low, S. J.; Kim, J.; Zhang, M.; Oh, P. L.; Nehrenberg, D.; Hua, K.; Kachman, S. D.; Moriyama, E. N.; Walter, J.; Peterson, D. A.; Pomp, D. Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 18933-18938
40. Rycroft, C. E.; Jones, M. R.; Gibson, G. R.; Rastall, R. A. A comparative in vitro evaluation of the fermentation properties of prebiotic oligosaccharides J. Appl. Microbiol. 2001, 91, 878-887 (Pubitemid 32989652)
41. Metwally, M. M.; El-Shibiny, S.; Dieb, S. M. E.; El-Etriby, H. M. M.; Assem, F. A. Large scale preparation and growth promoting effects on Bifidobacterium of glycomacropeptide from sweet whey Egypt. J. Dairy Sci. 2001, 29, 29-36 (Pubitemid 33298631)
42. Bouhnik, Y.; Attar, A.; Joly, F. A.; Riottot, M.; Dyard, F.; Flourié, B. Lactulose ingestion increases faecal bifidobacterial counts: a randomised double-blind study in healthy humans Eur. J. Clin. Nutr. 2004, 58, 462-466 (Pubitemid 38443706)
43. Cardelle-Cobas, A.; Fernández, M.; Salazar, N.; Martínez-Villaluenga, C.; Villamiel, M.; Ruas-Madiedo, P.; de los Reyes-Gavilán, C. G. Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose J. Dairy Res. 2009, 76, 317-325
44. Bourriaud, C.; Robins, R. J.; Martin, L.; Kozlowski, F.; Tenailleau, E.; Cherbut, C.; Michel, C. Lactate is mainly fermented to butyrate by human intestinal microfloras but inter-individual variation is evident J. Appl. Microbiol. 2005, 99, 201-212 (Pubitemid 40897005)
45. Hughes, S. A.; Shewry, P. R.; Gibson, G. R.; McCleary, B. V.; Rastall, R. A. In vitro fermentation of oat and barley derived β-glucans by human faecal microbiota FEMS Microbiol. Ecol. 2008, 64, 482-493 (Pubitemid 351644814)
46. Reid, G.; Sanders, M. E.; Gaskins, H. R.; Gibson, G. R.; Mercenier, A.; Rastall, R.; Roberfroid, M.; Rowland, I.; Cherbut, C.; Klaenhammer, T. R. New scientific paradigms for probiotics and prebiotics J. Clin. Gastroenterol. 2003, 37, 105-118 (Pubitemid 36875569)