Characterisation of a C1QTNF5 Ser163Arg Knock-In mouse model of Late-Onset retinal macular degeneration

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Shu, Xinhua ^a,c   Luhmann, Ulrich F O ^b   Aleman, Tomas S ^d   Barker, Susan E ^b   Lennon, Alan ^a   Tulloch, Brian ^a   Chen, Mei ^e   Xu, Heping ^e   Jacobson, Samuel G ^d   Ali, Robin ^b   Wright, Alan F ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; C1QTNF5 PROTEIN, HUMAN; COLLAGEN;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOFLUORESCENCE IMAGING; BRUCH MEMBRANE; C1QTNF5 GENE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ELECTRORETINOGRAPHY; EMBRYONIC STEM CELL; FEMALE; GENE; GENE OVEREXPRESSION; GENE TARGETING; GENOTYPE; HISTOPATHOLOGY; HOMOLOGOUS RECOMBINATION; HUMAN; IN VIVO STUDY; LASER COAGULATION; LATE ONSET RETINA MACULA DEGENERATION; MALE; MOLECULAR GENETICS; MOUSE; NONHUMAN; PHENOTYPE; PIGMENT EPITHELIUM; POINT MUTATION; RETINA MACULA DEGENERATION; SCANNING LASER OPHTHALMOSCOPY; SITE DIRECTED MUTAGENESIS; SUBRETINAL NEOVASCULARIZATION; WILD TYPE; ANIMAL; DISEASE MODEL; GENETICS; HELA CELL; LASER; METABOLISM; NUCLEOTIDE SEQUENCE; ONSET AGE; PATHOLOGY; PATHOPHYSIOLOGY; RETINA;

MURINAE; MUS;

AGE OF ONSET; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CHOROIDAL NEOVASCULARIZATION; COLLAGEN; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; FEMALE; GENE KNOCK-IN TECHNIQUES; HELA CELLS; HOMOLOGOUS RECOMBINATION; HUMANS; LASERS; LIGHT COAGULATION; MACULAR DEGENERATION; MALE; MICE; PHENOTYPE; RETINA;

EID: 81155131532     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027433     Document Type: Article

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