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Volumn 38, Issue 6, 2011, Pages 764-775

MicroRNAs: Toward the clinic for breast cancer patients

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; MICRORNA;

EID: 81155124249     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2011.08.005     Document Type: Article
Times cited : (30)

References (136)
  • 2
    • 69449090120 scopus 로고    scopus 로고
    • Thresholds for therapies: Highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009
    • A. Goldhirsch, J.N. Ingle, R.D. Gelber, A.S. Coates, B. Thurlimann, and H.J. Senn Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009 Ann Oncol 20 2009 1319 1329
    • (2009) Ann Oncol , vol.20 , pp. 1319-1329
    • Goldhirsch, A.1    Ingle, J.N.2    Gelber, R.D.3    Coates, A.S.4    Thurlimann, B.5    Senn, H.J.6
  • 3
    • 23844555119 scopus 로고    scopus 로고
    • MiRNA gene expression deregulation in human breast cancer
    • M.V. Iorio, M. Ferracin, and C.G. Liu MiRNA gene expression deregulation in human breast cancer Cancer Res 65 2005 7065 7070
    • (2005) Cancer Res , vol.65 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3
  • 4
    • 77953869515 scopus 로고    scopus 로고
    • Micro-RNAs and breast cancer
    • J. Le Quesne, and C. Caldas Micro-RNAs and breast cancer Mol Oncol 4 2010 230 241
    • (2010) Mol Oncol , vol.4 , pp. 230-241
    • Le Quesne, J.1    Caldas, C.2
  • 6
    • 36849078711 scopus 로고    scopus 로고
    • Let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • F. Yu, H. Yao, and P. Zhu let-7 regulates self renewal and tumorigenicity of breast cancer cells Cell 131 2007 1109 1123
    • (2007) Cell , vol.131 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3
  • 7
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
    • G.K. Scott, A. Goga, D. Bhaumik, C.E. Berger, C.S. Sullivan, and C.C. Benz Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b J Biol Chem 282 2007 1479 1486
    • (2007) J Biol Chem , vol.282 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3    Berger, C.E.4    Sullivan, C.S.5    Benz, C.C.6
  • 8
    • 77952360640 scopus 로고    scopus 로고
    • MiRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling
    • Z. Yu, N.E. Willmarth, and J. Zhou miRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling Proc Natl Acad Sci U S A 107 2010 8231 8236
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 8231-8236
    • Yu, Z.1    Willmarth, N.E.2    Zhou, J.3
  • 9
    • 49749086530 scopus 로고    scopus 로고
    • A cyclin D1/miRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation
    • Z. Yu, C. Wang, and M. Wang A cyclin D1/miRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation J Cell Biol 182 2008 509 517
    • (2008) J Cell Biol , vol.182 , pp. 509-517
    • Yu, Z.1    Wang, C.2    Wang, M.3
  • 10
    • 33750376591 scopus 로고    scopus 로고
    • Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA
    • A. Hossain, M.T. Kuo, and G.F. Saunders Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA Mol Cell Biol 26 2006 8191 8201
    • (2006) Mol Cell Biol , vol.26 , pp. 8191-8201
    • Hossain, A.1    Kuo, M.T.2    Saunders, G.F.3
  • 11
    • 79957907561 scopus 로고    scopus 로고
    • MiR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1
    • H. Li, C. Bian, L. Liao, J. Li, and R.C. Zhao miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1 Breast Cancer Res Treat 126 2010 565 575
    • (2010) Breast Cancer Res Treat , vol.126 , pp. 565-575
    • Li, H.1    Bian, C.2    Liao, L.3    Li, J.4    Zhao, R.C.5
  • 12
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • J.P. Thiery, H. Acloque, R.Y. Huang, and M.A. Nieto Epithelial- mesenchymal transitions in development and disease Cell 139 2009 871 890
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 13
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • P.A. Gregory, A.G. Bert, and E.L. Paterson The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 Nat Cell Biol 10 2008 593 601
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3
  • 14
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • M. Korpal, E.S. Lee, G. Hu, and Y. Kang The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2 J Biol Chem 283 2008 14910 14914
    • (2008) J Biol Chem , vol.283 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 15
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • S.M. Park, A.B. Gaur, E. Lengyel, and M.E. Peter The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2 Genes Dev 22 2008 894 907
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 16
    • 64149089915 scopus 로고    scopus 로고
    • Suppression of cell growth and invasion by miR-205 in breast cancer
    • H. Wu, S. Zhu, and Y.Y. Mo Suppression of cell growth and invasion by miR-205 in breast cancer Cell Res 19 2009 439 448
    • (2009) Cell Res , vol.19 , pp. 439-448
    • Wu, H.1    Zhu, S.2    Mo, Y.Y.3
  • 17
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by miRNA-10b in breast cancer
    • L. Ma, J. Teruya-Feldstein, and R.A. Weinberg Tumour invasion and metastasis initiated by miRNA-10b in breast cancer Nature 449 2007 682 688
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 18
    • 77950665077 scopus 로고    scopus 로고
    • Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
    • L. Ma, F. Reinhardt, and E. Pan Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model Nat Biotechnol 28 2010 341 347
    • (2010) Nat Biotechnol , vol.28 , pp. 341-347
    • Ma, L.1    Reinhardt, F.2    Pan, E.3
  • 19
    • 38849107424 scopus 로고    scopus 로고
    • The miRNAs miR-373 and miR-520c promote tumour invasion and metastasis
    • Q. Huang, K. Gumireddy, and M. Schrier The miRNAs miR-373 and miR-520c promote tumour invasion and metastasis Nat Cell Biol 10 2008 202 210
    • (2008) Nat Cell Biol , vol.10 , pp. 202-210
    • Huang, Q.1    Gumireddy, K.2    Schrier, M.3
  • 20
    • 40249092910 scopus 로고    scopus 로고
    • MiRNA-21 targets tumor suppressor genes in invasion and metastasis
    • S. Zhu, H. Wu, F. Wu, D. Nie, S. Sheng, and Y.Y. Mo MiRNA-21 targets tumor suppressor genes in invasion and metastasis Cell Res 18 2008 350 359
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5    Mo, Y.Y.6
  • 21
    • 47549109566 scopus 로고    scopus 로고
    • MiRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
    • Z. Lu, M. Liu, and V. Stribinskis MiRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene Oncogene 27 2008 4373 4379
    • (2008) Oncogene , vol.27 , pp. 4373-4379
    • Lu, Z.1    Liu, M.2    Stribinskis, V.3
  • 22
    • 67649783639 scopus 로고    scopus 로고
    • Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma
    • L. Qi, J. Bart, and L.P. Tan Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma BMC Cancer 9 2009 163
    • (2009) BMC Cancer , vol.9 , pp. 163
    • Qi, L.1    Bart, J.2    Tan, L.P.3
  • 23
    • 64849111009 scopus 로고    scopus 로고
    • Clinical significance of miR-21 expression in breast cancer: SYBR-Green I-based real-time RT-PCR study of invasive ductal carcinoma
    • G.L. Huang, X.H. Zhang, and G.L. Guo Clinical significance of miR-21 expression in breast cancer: SYBR-Green I-based real-time RT-PCR study of invasive ductal carcinoma Oncol Rep 21 2009 673 679
    • (2009) Oncol Rep , vol.21 , pp. 673-679
    • Huang, G.L.1    Zhang, X.H.2    Guo, G.L.3
  • 24
    • 38049115129 scopus 로고    scopus 로고
    • Endogenous human miRNAs that suppress breast cancer metastasis
    • S.F. Tavazoie, C. Alarcon, and T. Oskarsson Endogenous human miRNAs that suppress breast cancer metastasis Nature 451 2008 147 152
    • (2008) Nature , vol.451 , pp. 147-152
    • Tavazoie, S.F.1    Alarcon, C.2    Oskarsson, T.3
  • 25
    • 77953898940 scopus 로고    scopus 로고
    • A MiRNA targeting dicer for metastasis control
    • G. Martello, A. Rosato, and F. Ferrari A MiRNA targeting dicer for metastasis control Cell 141 2010 1195 1207
    • (2010) Cell , vol.141 , pp. 1195-1207
    • Martello, G.1    Rosato, A.2    Ferrari, F.3
  • 26
    • 37549024511 scopus 로고    scopus 로고
    • MiRNA expression profiling of human breast cancer identifies new markers of tumor subtype
    • C. Blenkiron, L.D. Goldstein, and N.P. Thorne MiRNA expression profiling of human breast cancer identifies new markers of tumor subtype Genome Biol 8 2007 R214
    • (2007) Genome Biol , vol.8 , pp. 214
    • Blenkiron, C.1    Goldstein, L.D.2    Thorne, N.P.3
  • 27
    • 33748624597 scopus 로고    scopus 로고
    • Optimized high-throughput miRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies
    • M.D. Mattie, C.C. Benz, and J. Bowers Optimized high-throughput miRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies Mol Cancer 5 2006 24
    • (2006) Mol Cancer , vol.5 , pp. 24
    • Mattie, M.D.1    Benz, C.C.2    Bowers, J.3
  • 28
    • 69949189728 scopus 로고    scopus 로고
    • MiRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer
    • A.J. Lowery, N. Miller, and A. Devaney MiRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer Breast Cancer Res 11 2009 R27
    • (2009) Breast Cancer Res , vol.11 , pp. 27
    • Lowery, A.J.1    Miller, N.2    Devaney, A.3
  • 29
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines
    • B.D. Adams, H. Furneaux, and B.A. White The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines Mol Endocrinol 21 2007 1132 1147
    • (2007) Mol Endocrinol , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 30
    • 48549099077 scopus 로고    scopus 로고
    • MiR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer
    • N. Kondo, T. Toyama, H. Sugiura, Y. Fujii, and H. Yamashita miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer Cancer Res 68 2008 5004 5008
    • (2008) Cancer Res , vol.68 , pp. 5004-5008
    • Kondo, N.1    Toyama, T.2    Sugiura, H.3    Fujii, Y.4    Yamashita, H.5
  • 31
    • 67749113293 scopus 로고    scopus 로고
    • The role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells
    • B.D. Adams, D.M. Cowee, and B.A. White The role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells Mol Endocrinol 23 2009 1215 1230
    • (2009) Mol Endocrinol , vol.23 , pp. 1215-1230
    • Adams, B.D.1    Cowee, D.M.2    White, B.A.3
  • 32
    • 67650135755 scopus 로고    scopus 로고
    • MiR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA
    • D.P. Pandey, and D. Picard miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA Mol Cell Biol 29 2009 3783 3790
    • (2009) Mol Cell Biol , vol.29 , pp. 3783-3790
    • Pandey, D.P.1    Picard, D.2
  • 33
    • 77949617195 scopus 로고    scopus 로고
    • An estrogen receptor alpha suppressor, miRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples
    • J. Xiong, D. Yu, and N. Wei An estrogen receptor alpha suppressor, miRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples FEBS J 277 2010 1684 1694
    • (2010) FEBS J , vol.277 , pp. 1684-1694
    • Xiong, J.1    Yu, D.2    Wei, N.3
  • 34
    • 79954842560 scopus 로고    scopus 로고
    • Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer
    • Y. Zhao, C. Deng, and J. Wang Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer Breast Cancer Res Treat 127 2010 69 80
    • (2010) Breast Cancer Res Treat , vol.127 , pp. 69-80
    • Zhao, Y.1    Deng, C.2    Wang, J.3
  • 35
    • 74249123376 scopus 로고    scopus 로고
    • MiR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells
    • R. Spizzo, M.S. Nicoloso, and L. Lupini miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells Cell Death Differ 17 2010 246 254
    • (2010) Cell Death Differ , vol.17 , pp. 246-254
    • Spizzo, R.1    Nicoloso, M.S.2    Lupini, L.3
  • 36
    • 69049096130 scopus 로고    scopus 로고
    • Estradiol-regulated miRNAs control estradiol response in breast cancer cells
    • P. Bhat-Nakshatri, G. Wang, and N.R. Collins Estradiol-regulated miRNAs control estradiol response in breast cancer cells Nucleic Acids Res 37 2009 4850 4861
    • (2009) Nucleic Acids Res , vol.37 , pp. 4850-4861
    • Bhat-Nakshatri, P.1    Wang, G.2    Collins, N.R.3
  • 37
    • 70350528663 scopus 로고    scopus 로고
    • Widespread estrogen-dependent repression of miRNAs involved in breast tumor cell growth
    • G. Maillot, M. Lacroix-Triki, and S. Pierredon Widespread estrogen-dependent repression of miRNAs involved in breast tumor cell growth Cancer Res 69 2009 8332 8340
    • (2009) Cancer Res , vol.69 , pp. 8332-8340
    • Maillot, G.1    Lacroix-Triki, M.2    Pierredon, S.3
  • 38
    • 65849267719 scopus 로고    scopus 로고
    • Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells
    • N.S. Wickramasinghe, T.T. Manavalan, S.M. Dougherty, K.A. Riggs, Y. Li, and C.M. Klinge Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells Nucleic Acids Res 37 2009 2584 2595
    • (2009) Nucleic Acids Res , vol.37 , pp. 2584-2595
    • Wickramasinghe, N.S.1    Manavalan, T.T.2    Dougherty, S.M.3    Riggs, K.A.4    Li, Y.5    Klinge, C.M.6
  • 39
    • 70349463161 scopus 로고    scopus 로고
    • The estrogen receptor-alpha-induced miRNA signature regulates itself and its transcriptional response
    • L. Castellano, G. Giamas, and J. Jacob The estrogen receptor-alpha- induced miRNA signature regulates itself and its transcriptional response Proc Natl Acad Sci U S A 106 2009 15732 15737
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 15732-15737
    • Castellano, L.1    Giamas, G.2    Jacob, J.3
  • 40
    • 57649174634 scopus 로고    scopus 로고
    • MiRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
    • J.J. Zhao, J. Lin, and H. Yang MiRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer J Biol Chem 283 2008 31079 31086
    • (2008) J Biol Chem , vol.283 , pp. 31079-31086
    • Zhao, J.J.1    Lin, J.2    Yang, H.3
  • 41
    • 77952921840 scopus 로고    scopus 로고
    • MiRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer
    • G. Di Leva, P. Gasparini, and C. Piovan MiRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer J Natl Cancer Inst 102 2010 706 721
    • (2010) J Natl Cancer Inst , vol.102 , pp. 706-721
    • Di Leva, G.1    Gasparini, P.2    Piovan, C.3
  • 42
    • 65549110881 scopus 로고    scopus 로고
    • MiRNA-205 regulates HER3 in human breast cancer
    • M.V. Iorio, P. Casalini, and C. Piovan miRNA-205 regulates HER3 in human breast cancer Cancer Res 69 2009 2195 2200
    • (2009) Cancer Res , vol.69 , pp. 2195-2200
    • Iorio, M.V.1    Casalini, P.2    Piovan, C.3
  • 43
    • 34447319406 scopus 로고    scopus 로고
    • Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA
    • R. Duan, C. Pak, and P. Jin Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA Hum Mol Genet 16 2007 1124 1131
    • (2007) Hum Mol Genet , vol.16 , pp. 1124-1131
    • Duan, R.1    Pak, C.2    Jin, P.3
  • 44
    • 66249089505 scopus 로고    scopus 로고
    • Germline mutation of miRNA-125a is associated with breast cancer
    • W. Li, R. Duan, F. Kooy, S.L. Sherman, W. Zhou, and P. Jin Germline mutation of miRNA-125a is associated with breast cancer J Med Genet 46 2009 358 360
    • (2009) J Med Genet , vol.46 , pp. 358-360
    • Li, W.1    Duan, R.2    Kooy, F.3    Sherman, S.L.4    Zhou, W.5    Jin, P.6
  • 45
    • 53349120042 scopus 로고    scopus 로고
    • A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis
    • J. Shen, C.B. Ambrosone, R.A. DiCioccio, K. Odunsi, S.B. Lele, and H. Zhao A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis Carcinogenesis 29 2008 1963 1966
    • (2008) Carcinogenesis , vol.29 , pp. 1963-1966
    • Shen, J.1    Ambrosone, C.B.2    Dicioccio, R.A.3    Odunsi, K.4    Lele, S.B.5    Zhao, H.6
  • 46
    • 58349104128 scopus 로고    scopus 로고
    • Common genetic variants in pre-miRNAs were associated with increased risk of breast cancer in Chinese women
    • Z. Hu, J. Liang, and Z. Wang Common genetic variants in pre-miRNAs were associated with increased risk of breast cancer in Chinese women Hum Mutat 30 2009 79 84
    • (2009) Hum Mutat , vol.30 , pp. 79-84
    • Hu, Z.1    Liang, J.2    Wang, Z.3
  • 47
    • 74049157786 scopus 로고    scopus 로고
    • Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases
    • I. Catucci, R. Yang, and P. Verderio Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases Hum Mutat 31 2010 E1052 E1057
    • (2010) Hum Mutat , vol.31
    • Catucci, I.1    Yang, R.2    Verderio, P.3
  • 48
    • 78650986168 scopus 로고    scopus 로고
    • The association between two polymorphisms in pre-miRNAs and breast cancer risk: A meta-analysis
    • L.B. Gao, P. Bai, and X.M. Pan The association between two polymorphisms in pre-miRNAs and breast cancer risk: a meta-analysis Breast Cancer Res Treat 125 2010 571 574
    • (2010) Breast Cancer Res Treat , vol.125 , pp. 571-574
    • Gao, L.B.1    Bai, P.2    Pan, X.M.3
  • 49
    • 67650995908 scopus 로고    scopus 로고
    • MiRNA miR-196a-2 and breast cancer: A genetic and epigenetic association study and functional analysis
    • A.E. Hoffman, T. Zheng, and C. Yi miRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis Cancer Res 69 2009 5970 5977
    • (2009) Cancer Res , vol.69 , pp. 5970-5977
    • Hoffman, A.E.1    Zheng, T.2    Yi, C.3
  • 50
    • 77953122376 scopus 로고    scopus 로고
    • A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk
    • R. Yang, B. Schlehe, and K. Hemminki A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk Breast Cancer Res Treat 121 2010 693 702
    • (2010) Breast Cancer Res Treat , vol.121 , pp. 693-702
    • Yang, R.1    Schlehe, B.2    Hemminki, K.3
  • 51
    • 58949101499 scopus 로고    scopus 로고
    • A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women
    • S. Tchatchou, A. Jung, and K. Hemminki A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women Carcinogenesis 30 2009 59 64
    • (2009) Carcinogenesis , vol.30 , pp. 59-64
    • Tchatchou, S.1    Jung, A.2    Hemminki, K.3
  • 52
    • 70349682881 scopus 로고    scopus 로고
    • An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset
    • F. Song, H. Zheng, and B. Liu An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset Clin Cancer Res 15 2009 6292 6300
    • (2009) Clin Cancer Res , vol.15 , pp. 6292-6300
    • Song, F.1    Zheng, H.2    Liu, B.3
  • 53
    • 48749122914 scopus 로고    scopus 로고
    • Circulating miRNAs as stable blood-based markers for cancer detection
    • P.S. Mitchell, R.K. Parkin, and E.M. Kroh Circulating miRNAs as stable blood-based markers for cancer detection Proc Natl Acad Sci U S A 105 2008 10513 10518
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 10513-10518
    • Mitchell, P.S.1    Parkin, R.K.2    Kroh, E.M.3
  • 55
    • 77956117169 scopus 로고    scopus 로고
    • Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage disease
    • H.M. Heneghan, N. Miller, R. Kelly, J. Newell, and M.J. Kerin Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage disease Oncologist 15 2010 673 682
    • (2010) Oncologist , vol.15 , pp. 673-682
    • Heneghan, H.M.1    Miller, N.2    Kelly, R.3    Newell, J.4    Kerin, M.J.5
  • 56
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • C.M. Perou, T. Sorlie, and M.B. Eisen Molecular portraits of human breast tumours Nature 406 2000 747 752
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 57
    • 44849135294 scopus 로고    scopus 로고
    • An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer
    • K.H. Salter, C.R. Acharya, and K.S. Walters An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer PLoS One 3 2008 e1908
    • (2008) PLoS One , vol.3 , pp. 1908
    • Salter, K.H.1    Acharya, C.R.2    Walters, K.S.3
  • 58
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of miRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
    • O. Kovalchuk, J. Filkowski, and J. Meservy Involvement of miRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin Mol Cancer. Ther 7 2008 2152 2159
    • (2008) Mol Cancer. Ther , vol.7 , pp. 2152-2159
    • Kovalchuk, O.1    Filkowski, J.2    Meservy, J.3
  • 59
    • 56449092072 scopus 로고    scopus 로고
    • MiRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
    • T.E. Miller, K. Ghoshal, and B. Ramaswamy MiRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1 J Biol Chem 283 2008 29897 29903
    • (2008) J Biol Chem , vol.283 , pp. 29897-29903
    • Miller, T.E.1    Ghoshal, K.2    Ramaswamy, B.3
  • 60
    • 57749105325 scopus 로고    scopus 로고
    • MiRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer
    • N. Yang, S. Kaur, and S. Volinia MiRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer Cancer Res 68 2008 10307 10314
    • (2008) Cancer Res , vol.68 , pp. 10307-10314
    • Yang, N.1    Kaur, S.2    Volinia, S.3
  • 61
    • 77956995581 scopus 로고    scopus 로고
    • Alterations of miRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
    • I.P. Pogribny, J.N. Filkowski, V.P. Tryndyak, A. Golubov, S.I. Shpyleva, and O. Kovalchuk Alterations of miRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin Int J Cancer 127 2010 1785 1794
    • (2010) Int J Cancer , vol.127 , pp. 1785-1794
    • Pogribny, I.P.1    Filkowski, J.N.2    Tryndyak, V.P.3    Golubov, A.4    Shpyleva, S.I.5    Kovalchuk, O.6
  • 62
    • 77954378366 scopus 로고    scopus 로고
    • MiRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
    • M. Zhou, Z. Liu, and Y. Zhao MiRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression J Biol Chem 285 2010 21496 21507
    • (2010) J Biol Chem , vol.285 , pp. 21496-21507
    • Zhou, M.1    Liu, Z.2    Zhao, Y.3
  • 63
    • 77952944048 scopus 로고    scopus 로고
    • MiRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer
    • W. Kong, L. He, and M. Coppola MiRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer J Biol Chem 285 2010 17869 17879
    • (2010) J Biol Chem , vol.285 , pp. 17869-17879
    • Kong, W.1    He, L.2    Coppola, M.3
  • 65
    • 40949137731 scopus 로고    scopus 로고
    • Hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer
    • C. Camps, F.M. Buffa, and S. Colella hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer Clin Cancer Res 14 2008 1340 1348
    • (2008) Clin Cancer Res , vol.14 , pp. 1340-1348
    • Camps, C.1    Buffa, F.M.2    Colella, S.3
  • 66
    • 51349103144 scopus 로고    scopus 로고
    • Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer
    • J.A. Foekens, A.M. Sieuwerts, and M. Smid Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer Proc Natl Acad Sci U S A 105 2008 13021 13026
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13021-13026
    • Foekens, J.A.1    Sieuwerts, A.M.2    Smid, M.3
  • 67
  • 68
    • 55549120234 scopus 로고    scopus 로고
    • MiRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
    • L.X. Yan, X.F. Huang, and Q. Shao MiRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis RNA 14 2008 2348 2360
    • (2008) RNA , vol.14 , pp. 2348-2360
    • Yan, L.X.1    Huang, X.F.2    Shao, Q.3
  • 69
    • 69049120925 scopus 로고    scopus 로고
    • High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1
    • B. Qian, D. Katsaros, and L. Lu High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1 Breast Cancer Res Treat 117 2009 131 140
    • (2009) Breast Cancer Res Treat , vol.117 , pp. 131-140
    • Qian, B.1    Katsaros, D.2    Lu, L.3
  • 70
    • 79954748720 scopus 로고    scopus 로고
    • MiRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer
    • F.G. Rodriguez-Gonzalez, A.M. Sieuwerts, and M. Smid MiRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer Breast Cancer Res Treat 127 2010 43 51
    • (2010) Breast Cancer Res Treat , vol.127 , pp. 43-51
    • Rodriguez-Gonzalez, F.G.1    Sieuwerts, A.M.2    Smid, M.3
  • 71
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of miRNAs in vivo with 'antagomirs'
    • J. Krutzfeldt, N. Rajewsky, and R. Braich Silencing of miRNAs in vivo with 'antagomirs' Nature 438 2005 685 689
    • (2005) Nature , vol.438 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 73
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic miRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • J. Kota, R.R. Chivukula, and K.A. O'Donnell Therapeutic miRNA delivery suppresses tumorigenesis in a murine liver cancer model Cell 137 2009 1005 1017
    • (2009) Cell , vol.137 , pp. 1005-1017
    • Kota, J.1    Chivukula, R.R.2    O'Donnell, K.A.3
  • 74
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-kappaB, Lin28, Let-7 MiRNA, and IL6 links inflammation to cell transformation
    • D. Iliopoulos, H.A. Hirsch, and K. Struhl An epigenetic switch involving NF-kappaB, Lin28, Let-7 MiRNA, and IL6 links inflammation to cell transformation Cell 139 2009 693 706
    • (2009) Cell , vol.139 , pp. 693-706
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 75
    • 58149239686 scopus 로고    scopus 로고
    • Genomic loss of miRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
    • S. Varambally, Q. Cao, and R.S. Mani Genomic loss of miRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer Science 322 2008 1695 1699
    • (2008) Science , vol.322 , pp. 1695-1699
    • Varambally, S.1    Cao, Q.2    Mani, R.S.3
  • 76
    • 77954230727 scopus 로고    scopus 로고
    • MiR-10b targets Tiam1: Implications for Rac activation and carcinoma migration
    • C.H. Moriarty, B. Pursell, and A.M. Mercurio miR-10b targets Tiam1: implications for Rac activation and carcinoma migration J Biol Chem 285 2010 20541 20546
    • (2010) J Biol Chem , vol.285 , pp. 20541-20546
    • Moriarty, C.H.1    Pursell, B.2    Mercurio, A.M.3
  • 77
    • 77953208358 scopus 로고    scopus 로고
    • MiR-1226 targets expression of the mucin 1 oncoprotein and induces cell death
    • C. Jin, H. Rajabi, and D. Kufe miR-1226 targets expression of the mucin 1 oncoprotein and induces cell death Int J Oncol 37 2010 61 69
    • (2010) Int J Oncol , vol.37 , pp. 61-69
    • Jin, C.1    Rajabi, H.2    Kufe, D.3
  • 78
    • 65649087527 scopus 로고    scopus 로고
    • Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues
    • A.B. Hui, W. Shi, and P.C. Boutros Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues Lab Invest 89 2009 597 606
    • (2009) Lab Invest , vol.89 , pp. 597-606
    • Hui, A.B.1    Shi, W.2    Boutros, P.C.3
  • 79
    • 77950584927 scopus 로고    scopus 로고
    • MiRNA-125a represses cell growth by targeting HuR in breast cancer
    • X. Guo, Y. Wu, and R.S. Hartley MiRNA-125a represses cell growth by targeting HuR in breast cancer RNA Biol 6 2009 575 583
    • (2009) RNA Biol , vol.6 , pp. 575-583
    • Guo, X.1    Wu, Y.2    Hartley, R.S.3
  • 80
    • 72449132936 scopus 로고    scopus 로고
    • A short hairpin DNA analogous to miR-125b inhibits C-Raf expression, proliferation, and survival of breast cancer cells
    • M.H. Hofmann, J. Heinrich, G. Radziwill, and K. Moelling A short hairpin DNA analogous to miR-125b inhibits C-Raf expression, proliferation, and survival of breast cancer cells Mol Cancer Res 7 2009 1635 1644
    • (2009) Mol Cancer Res , vol.7 , pp. 1635-1644
    • Hofmann, M.H.1    Heinrich, J.2    Radziwill, G.3    Moelling, K.4
  • 81
    • 70349333224 scopus 로고    scopus 로고
    • Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b
    • S. Komagata, M. Nakajima, S. Takagi, T. Mohri, T. Taniya, and T. Yokoi Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b Mol Pharmacol 76 2009 702 709
    • (2009) Mol Pharmacol , vol.76 , pp. 702-709
    • Komagata, S.1    Nakajima, M.2    Takagi, S.3    Mohri, T.4    Taniya, T.5    Yokoi, T.6
  • 82
    • 77953178125 scopus 로고    scopus 로고
    • MUCIN 1 oncoprotein expression is suppressed by the miR-125b oncomir
    • H. Rajabi, C. Jin, R. Ahmad, C. McClary, M.D. Joshi, and D. Kufe MUCIN 1 oncoprotein expression is suppressed by the miR-125b oncomir Genes Cancer 1 2010 62 68
    • (2010) Genes Cancer , vol.1 , pp. 62-68
    • Rajabi, H.1    Jin, C.2    Ahmad, R.3    McClary, C.4    Joshi, M.D.5    Kufe, D.6
  • 83
    • 70349741005 scopus 로고    scopus 로고
    • A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis
    • P. Saetrom, J. Biesinger, and S.M. Li A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis Cancer Res 69 2009 7459 7465
    • (2009) Cancer Res , vol.69 , pp. 7459-7465
    • Saetrom, P.1    Biesinger, J.2    Li, S.M.3
  • 84
    • 77955755505 scopus 로고    scopus 로고
    • Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MiRNA expression in solid tumors
    • L.F. Sempere, M. Preis, and T. Yezefski Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MiRNA expression in solid tumors Clin Cancer Res 16 2010 4246 4255
    • (2010) Clin Cancer Res , vol.16 , pp. 4246-4255
    • Sempere, L.F.1    Preis, M.2    Yezefski, T.3
  • 85
    • 54449099588 scopus 로고    scopus 로고
    • The cell growth suppressor, mir-126, targets IRS-1
    • J. Zhang, Y.Y. Du, and Y.F. Lin The cell growth suppressor, mir-126, targets IRS-1 Biochem Biophys Res Commun 377 2008 136 140
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 136-140
    • Zhang, J.1    Du, Y.Y.2    Lin, Y.F.3
  • 86
    • 77957709001 scopus 로고    scopus 로고
    • The role of miRNA-128a in regulating TGFbeta signaling in letrozole-resistant breast cancer cells
    • S. Masri, Z. Liu, S. Phung, E. Wang, Y.C. Yuan, and S. Chen The role of miRNA-128a in regulating TGFbeta signaling in letrozole-resistant breast cancer cells Breast Cancer Res Treat 124 2010 89 990
    • (2010) Breast Cancer Res Treat , vol.124 , pp. 89-990
    • Masri, S.1    Liu, Z.2    Phung, S.3    Wang, E.4    Yuan, Y.C.5    Chen, S.6
  • 87
    • 75149124701 scopus 로고    scopus 로고
    • MiRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1
    • M. Sachdeva, and Y.Y. Mo MiRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1 Cancer Res 70 2010 378 387
    • (2010) Cancer Res , vol.70 , pp. 378-387
    • Sachdeva, M.1    Mo, Y.Y.2
  • 88
    • 67649448828 scopus 로고    scopus 로고
    • MiR-145 inhibits breast cancer cell growth through RTKN
    • S. Wang, C. Bian, and Z. Yang miR-145 inhibits breast cancer cell growth through RTKN Int J Oncol 34 2009 1461 1466
    • (2009) Int J Oncol , vol.34 , pp. 1461-1466
    • Wang, S.1    Bian, C.2    Yang, Z.3
  • 89
    • 52149102044 scopus 로고    scopus 로고
    • Expression of miRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells
    • D. Bhaumik, G.K. Scott, S. Schokrpur, C.K. Patil, J. Campisi, and C.C. Benz Expression of miRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells Oncogene 27 2008 5643 5647
    • (2008) Oncogene , vol.27 , pp. 5643-5647
    • Bhaumik, D.1    Scott, G.K.2    Schokrpur, S.3    Patil, C.K.4    Campisi, J.5    Benz, C.C.6
  • 90
    • 73249115584 scopus 로고    scopus 로고
    • Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
    • M. Persson, Y. Andren, J. Mark, H.M. Horlings, F. Persson, and G. Stenman Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck Proc Natl Acad Sci U S A 106 2009 18740 18744
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 18740-18744
    • Persson, M.1    Andren, Y.2    Mark, J.3    Horlings, H.M.4    Persson, F.5    Stenman, G.6
  • 91
    • 77951026718 scopus 로고    scopus 로고
    • MiRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene
    • S. Jiang, H.W. Zhang, and M.H. Lu MiRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene Cancer Res 70 2010 3119 3127
    • (2010) Cancer Res , vol.70 , pp. 3119-3127
    • Jiang, S.1    Zhang, H.W.2    Lu, M.H.3
  • 92
    • 55849123946 scopus 로고    scopus 로고
    • MiRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA
    • W. Kong, H. Yang, and L. He MiRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA Mol Cell Biol 28 2008 6773 6784
    • (2008) Mol Cell Biol , vol.28 , pp. 6773-6784
    • Kong, W.1    Yang, H.2    He, L.3
  • 93
    • 77956896318 scopus 로고    scopus 로고
    • Oncogenic Wip1 Phosphatase Is Inhibited by miR-16 in the DNA damage signaling pathway
    • X. Zhang, G. Wan, and S. Mlotshwa Oncogenic Wip1 Phosphatase Is Inhibited by miR-16 in the DNA damage signaling pathway Cancer Res 70 2010 7176 7186
    • (2010) Cancer Res , vol.70 , pp. 7176-7186
    • Zhang, X.1    Wan, G.2    Mlotshwa, S.3
  • 94
    • 33745168962 scopus 로고    scopus 로고
    • MiRNAs exhibit high frequency genomic alterations in human cancer
    • L. Zhang, J. Huang, and N. Yang miRNAs exhibit high frequency genomic alterations in human cancer Proc Natl Acad Sci U S A 103 2006 9136 9141
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9136-9141
    • Zhang, L.1    Huang, J.2    Yang, N.3
  • 95
    • 58749083044 scopus 로고    scopus 로고
    • Novel genetic variants in miRNA genes and familial breast cancer
    • J. Shen, C.B. Ambrosone, and H. Zhao Novel genetic variants in miRNA genes and familial breast cancer Int J Cancer 124 2009 1178 1182
    • (2009) Int J Cancer , vol.124 , pp. 1178-1182
    • Shen, J.1    Ambrosone, C.B.2    Zhao, H.3
  • 96
    • 77953157907 scopus 로고    scopus 로고
    • Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer
    • H. Al-Nakhle, P.A. Burns, and M. Cummings Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer Cancer Res 70 2010 4778 4784
    • (2010) Cancer Res , vol.70 , pp. 4778-4784
    • Al-Nakhle, H.1    Burns, P.A.2    Cummings, M.3
  • 97
    • 77952507643 scopus 로고    scopus 로고
    • MiR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells
    • S. Cascio, A. D'Andrea, and R. Ferla miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells J Cell Physiol 224 2010 242 249
    • (2010) J Cell Physiol , vol.224 , pp. 242-249
    • Cascio, S.1    D'Andrea, A.2    Ferla, R.3
  • 98
    • 84984539125 scopus 로고    scopus 로고
    • MiRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells
    • W.H. Liu, S.H. Yeh, and C.C. Lu MiRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells Gastroenterology 136 2009 683 693
    • (2009) Gastroenterology , vol.136 , pp. 683-693
    • Liu, W.H.1    Yeh, S.H.2    Lu, C.C.3
  • 99
    • 77956342464 scopus 로고    scopus 로고
    • MiRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers
    • J.S. Imam, K. Buddavarapu, and J.S. Lee-Chang MiRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers Oncogene 29 2010 4971 4979
    • (2010) Oncogene , vol.29 , pp. 4971-4979
    • Imam, J.S.1    Buddavarapu, K.2    Lee-Chang, J.S.3
  • 100
    • 56149126489 scopus 로고    scopus 로고
    • MiRNA-196a targets annexin A1: A miRNA-mediated mechanism of annexin A1 downregulation in cancers
    • R. Luthra, R.R. Singh, and M.G. Luthra MiRNA-196a targets annexin A1: a miRNA-mediated mechanism of annexin A1 downregulation in cancers Oncogene 27 2008 6667 6678
    • (2008) Oncogene , vol.27 , pp. 6667-6678
    • Luthra, R.1    Singh, R.R.2    Luthra, M.G.3
  • 101
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • U. Burk, J. Schubert, and U. Wellner A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells EMBO Rep 9 2008 582 589
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3
  • 102
    • 66849140943 scopus 로고    scopus 로고
    • MiRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
    • D.R. Cochrane, N.S. Spoelstra, E.N. Howe, S.K. Nordeen, and J.K. Richer MiRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents Mol Cancer Ther 8 2009 1055 1066
    • (2009) Mol Cancer Ther , vol.8 , pp. 1055-1066
    • Cochrane, D.R.1    Spoelstra, N.S.2    Howe, E.N.3    Nordeen, S.K.4    Richer, J.K.5
  • 103
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Y. Shimono, M. Zabala, and R.W. Cho Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells Cell 138 2009 592 603
    • (2009) Cell , vol.138 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3
  • 105
    • 77951248184 scopus 로고    scopus 로고
    • E-cadherin transcriptional down-regulation by epigenetic and miRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells
    • V.P. Tryndyak, F.A. Beland, and I.P. Pogribny E-cadherin transcriptional down-regulation by epigenetic and miRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells Int J Cancer 126 2010 2575 2583
    • (2010) Int J Cancer , vol.126 , pp. 2575-2583
    • Tryndyak, V.P.1    Beland, F.A.2    Pogribny, I.P.3
  • 106
    • 77955172153 scopus 로고    scopus 로고
    • MiR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer
    • S. Uhlmann, J.D. Zhang, and A. Schwager miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer Oncogene 29 2010 4297 4306
    • (2010) Oncogene , vol.29 , pp. 4297-4306
    • Uhlmann, S.1    Zhang, J.D.2    Schwager, A.3
  • 107
    • 70349134366 scopus 로고    scopus 로고
    • MiRNA expression profiling of human metastatic cancers identifies cancer gene targets
    • R. Baffa, M. Fassan, and S. Volinia MiRNA expression profiling of human metastatic cancers identifies cancer gene targets J Pathol 219 2009 214 221
    • (2009) J Pathol , vol.219 , pp. 214-221
    • Baffa, R.1    Fassan, M.2    Volinia, S.3
  • 108
    • 34347266556 scopus 로고    scopus 로고
    • MiRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • S. Zhu, M.L. Si, H. Wu, and Y.Y. Mo MiRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1) J Biol Chem 282 2007 14328 14336
    • (2007) J Biol Chem , vol.282 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 109
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the miRNA miR-21 in breast cancer cells
    • L.B. Frankel, N.R. Christoffersen, A. Jacobsen, M. Lindow, A. Krogh, and A.H. Lund Programmed cell death 4 (PDCD4) is an important functional target of the miRNA miR-21 in breast cancer cells J Biol Chem 283 2008 1026 1033
    • (2008) J Biol Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 110
    • 67349254469 scopus 로고    scopus 로고
    • MiRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells
    • T. Li, D. Li, J. Sha, P. Sun, and Y. Huang MiRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells Biochem Biophys Res Commun 383 2009 280 285
    • (2009) Biochem Biophys Res Commun , vol.383 , pp. 280-285
    • Li, T.1    Li, D.2    Sha, J.3    Sun, P.4    Huang, Y.5
  • 111
    • 63049092022 scopus 로고    scopus 로고
    • Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach
    • Y. Yang, R. Chaerkady, M.A. Beer, J.T. Mendell, and A. Pandey Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach Proteomics 9 2009 1374 1384
    • (2009) Proteomics , vol.9 , pp. 1374-1384
    • Yang, Y.1    Chaerkady, R.2    Beer, M.A.3    Mendell, J.T.4    Pandey, A.5
  • 112
    • 77952948062 scopus 로고    scopus 로고
    • Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB
    • E.C. Connolly, K. Van Doorslaer, L.E. Rogler, and C.E. Rogler Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB Mol Cancer Res 8 2010 691 700
    • (2010) Mol Cancer Res , vol.8 , pp. 691-700
    • Connolly, E.C.1    Van Doorslaer, K.2    Rogler, L.E.3    Rogler, C.E.4
  • 113
    • 77950905590 scopus 로고    scopus 로고
    • MiRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression
    • B. Song, C. Wang, and J. Liu MiRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression J Exp Clin Cancer Res 29 2010 29
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 29
    • Song, B.1    Wang, C.2    Liu, J.3
  • 114
    • 70350362953 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of miRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotherapy resistance in breast tumor cells
    • L.Y. Bourguignon, C.C. Spevak, G. Wong, W. Xia, and E. Gilad Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of miRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotherapy resistance in breast tumor cells J Biol Chem 284 2009 26533 26546
    • (2009) J Biol Chem , vol.284 , pp. 26533-26546
    • Bourguignon, L.Y.1    Spevak, C.C.2    Wong, G.3    Xia, W.4    Gilad, E.5
  • 116
    • 59149091637 scopus 로고    scopus 로고
    • MiRNA regulation of DNA repair gene expression in hypoxic stress
    • M.E. Crosby, R. Kulshreshtha, M. Ivan, and P.M. Glazer MiRNA regulation of DNA repair gene expression in hypoxic stress Cancer Res 69 2009 1221 1229
    • (2009) Cancer Res , vol.69 , pp. 1221-1229
    • Crosby, M.E.1    Kulshreshtha, R.2    Ivan, M.3    Glazer, P.M.4
  • 117
    • 69749107748 scopus 로고    scopus 로고
    • MiRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT
    • Z. Zhang, H. Sun, and H. Dai MiRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT Cell Cycle 8 2009 2756 2768
    • (2009) Cell Cycle , vol.8 , pp. 2756-2768
    • Zhang, Z.1    Sun, H.2    Dai, H.3
  • 118
    • 77955287970 scopus 로고    scopus 로고
    • Regulation of the expression and activity of the antiangiogenic homeobox gene GAX/MEOX2 by ZEB2 and miRNA-221
    • Y. Chen, M. Banda, C.L. Speyer, J.S. Smith, A.B. Rabson, and D.H. Gorski Regulation of the expression and activity of the antiangiogenic homeobox gene GAX/MEOX2 by ZEB2 and miRNA-221 Mol Cell Biol 30 2010 3902 3913
    • (2010) Mol Cell Biol , vol.30 , pp. 3902-3913
    • Chen, Y.1    Banda, M.2    Speyer, C.L.3    Smith, J.S.4    Rabson, A.B.5    Gorski, D.H.6
  • 119
    • 33749487425 scopus 로고    scopus 로고
    • MiRNA regulates the expression of human cytochrome P450 1B1
    • Y. Tsuchiya, M. Nakajima, S. Takagi, T. Taniya, and T. Yokoi MiRNA regulates the expression of human cytochrome P450 1B1 Cancer Res 66 2006 9090 9098
    • (2006) Cancer Res , vol.66 , pp. 9090-9098
    • Tsuchiya, Y.1    Nakajima, M.2    Takagi, S.3    Taniya, T.4    Yokoi, T.5
  • 120
    • 69249088913 scopus 로고    scopus 로고
    • ST14 (suppression of tumorigenicity 14) gene is a target for miR-27b, and the inhibitory effect of ST14 on cell growth is independent of miR-27b regulation
    • Y. Wang, R. Rathinam, A. Walch, and S.K. Alahari ST14 (suppression of tumorigenicity 14) gene is a target for miR-27b, and the inhibitory effect of ST14 on cell growth is independent of miR-27b regulation J Biol Chem 284 2009 23094 23106
    • (2009) J Biol Chem , vol.284 , pp. 23094-23106
    • Wang, Y.1    Rathinam, R.2    Walch, A.3    Alahari, S.K.4
  • 121
    • 77954497664 scopus 로고    scopus 로고
    • MiRNA-27a indirectly regulates estrogen receptor {alpha} expression and hormone responsiveness in MCF-7 breast cancer cells
    • X. Li, S.U. Mertens-Talcott, S. Zhang, K. Kim, J. Ball, and S. Safe MiRNA-27a indirectly regulates estrogen receptor {alpha} expression and hormone responsiveness in MCF-7 breast cancer cells Endocrinology 151 2010 2462 2473
    • (2010) Endocrinology , vol.151 , pp. 2462-2473
    • Li, X.1    Mertens-Talcott, S.U.2    Zhang, S.3    Kim, K.4    Ball, J.5    Safe, S.6
  • 122
    • 36349001297 scopus 로고    scopus 로고
    • The oncogenic miRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells
    • S.U. Mertens-Talcott, S. Chintharlapalli, X. Li, and S. Safe The oncogenic miRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells Cancer Res 67 2007 11001 11011
    • (2007) Cancer Res , vol.67 , pp. 11001-11011
    • Mertens-Talcott, S.U.1    Chintharlapalli, S.2    Li, X.3    Safe, S.4
  • 123
    • 64049107465 scopus 로고    scopus 로고
    • MiR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis
    • C.A. Gebeshuber, K. Zatloukal, and J. Martinez miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis EMBO Rep 10 2009 400 405
    • (2009) EMBO Rep , vol.10 , pp. 400-405
    • Gebeshuber, C.A.1    Zatloukal, K.2    Martinez, J.3
  • 124
    • 63449104333 scopus 로고    scopus 로고
    • MiRNA-mediated regulation of Ubc9 expression in cancer cells
    • F. Wu, S. Zhu, Y. Ding, W.T. Beck, and Y.Y. Mo MiRNA-mediated regulation of Ubc9 expression in cancer cells Clin Cancer Res 15 2009 1550 1557
    • (2009) Clin Cancer Res , vol.15 , pp. 1550-1557
    • Wu, F.1    Zhu, S.2    Ding, Y.3    Beck, W.T.4    Mo, Y.Y.5
  • 125
    • 77954954098 scopus 로고    scopus 로고
    • Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells
    • F. Yu, H. Deng, H. Yao, Q. Liu, F. Su, and E. Song Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells Oncogene 29 2010 4194 4204
    • (2010) Oncogene , vol.29 , pp. 4194-4204
    • Yu, F.1    Deng, H.2    Yao, H.3    Liu, Q.4    Su, F.5    Song, E.6
  • 126
    • 77953780136 scopus 로고    scopus 로고
    • Concurrent suppression of integrin alpha5, radixin, and RhoA phenocopies the effects of miR-31 on metastasis
    • S. Valastyan, A. Chang, N. Benaich, F. Reinhardt, and R.A. Weinberg Concurrent suppression of integrin alpha5, radixin, and RhoA phenocopies the effects of miR-31 on metastasis Cancer Res 70 2010 5147 5154
    • (2010) Cancer Res , vol.70 , pp. 5147-5154
    • Valastyan, S.1    Chang, A.2    Benaich, N.3    Reinhardt, F.4    Weinberg, R.A.5
  • 127
    • 74149092809 scopus 로고    scopus 로고
    • Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1
    • Z. Liang, H. Wu, and J. Xia Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1 Biochem Pharmacol 79 2010 817 824
    • (2010) Biochem Pharmacol , vol.79 , pp. 817-824
    • Liang, Z.1    Wu, H.2    Xia, J.3
  • 129
    • 66049147178 scopus 로고    scopus 로고
    • MiRNAs 373 and 520c are downregulated in prostate cancer, suppress CD44 translation and enhance invasion of prostate cancer cells in vitro
    • K. Yang, A.M. Handorean, and K.A. Iczkowski MiRNAs 373 and 520c are downregulated in prostate cancer, suppress CD44 translation and enhance invasion of prostate cancer cells in vitro Int J Clin Exp Pathol 2 2009 361 369
    • (2009) Int J Clin Exp Pathol , vol.2 , pp. 361-369
    • Yang, K.1    Handorean, A.M.2    Iczkowski, K.A.3
  • 130
    • 77953751418 scopus 로고    scopus 로고
    • Downregulation of miRNA miR-520h by E1A contributes to anticancer activity
    • J.L. Su, P.B. Chen, and Y.H. Chen Downregulation of miRNA miR-520h by E1A contributes to anticancer activity Cancer Res 70 2010 5096 5108
    • (2010) Cancer Res , vol.70 , pp. 5096-5108
    • Su, J.L.1    Chen, P.B.2    Chen, Y.H.3
  • 131
    • 67651007292 scopus 로고    scopus 로고
    • MiRNA-661, a c/EBPalpha target, inhibits metastatic tumor antigen 1 and regulates its functions
    • S.D. Reddy, S.B. Pakala, K. Ohshiro, S.K. Rayala, and R. Kumar MiRNA-661, a c/EBPalpha target, inhibits metastatic tumor antigen 1 and regulates its functions Cancer Res 69 2009 5639 5642
    • (2009) Cancer Res , vol.69 , pp. 5639-5642
    • Reddy, S.D.1    Pakala, S.B.2    Ohshiro, K.3    Rayala, S.K.4    Kumar, R.5
  • 132
    • 77955466130 scopus 로고    scopus 로고
    • MiR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers
    • G. Vetter, A. Saumet, and M. Moes miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers Oncogene 29 2010 4436 4448
    • (2010) Oncogene , vol.29 , pp. 4436-4448
    • Vetter, G.1    Saumet, A.2    Moes, M.3
  • 133
    • 54249093368 scopus 로고    scopus 로고
    • MiRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions
    • S.D. Reddy, K. Ohshiro, S.K. Rayala, and R. Kumar MiRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions Cancer Res 68 2008 8195 8200
    • (2008) Cancer Res , vol.68 , pp. 8195-8200
    • Reddy, S.D.1    Ohshiro, K.2    Rayala, S.K.3    Kumar, R.4
  • 134
    • 65549120766 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor signaling in human cancer cells by miRNA-7
    • R.J. Webster, K.M. Giles, K.J. Price, P.M. Zhang, J.S. Mattick, and P.J. Leedman Regulation of epidermal growth factor receptor signaling in human cancer cells by miRNA-7 J Biol Chem 284 2009 5731 5741
    • (2009) J Biol Chem , vol.284 , pp. 5731-5741
    • Webster, R.J.1    Giles, K.M.2    Price, K.J.3    Zhang, P.M.4    Mattick, J.S.5    Leedman, P.J.6
  • 135
    • 77649275464 scopus 로고    scopus 로고
    • MiR-9, a MYC/MYCN-activated miRNA, regulates E-cadherin and cancer metastasis
    • L. Ma, J. Young, and H. Prabhala miR-9, a MYC/MYCN-activated miRNA, regulates E-cadherin and cancer metastasis Nat Cell Biol 12 2010 247 256
    • (2010) Nat Cell Biol , vol.12 , pp. 247-256
    • Ma, L.1    Young, J.2    Prabhala, H.3
  • 136
    • 77954444125 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women
    • T. Kontorovich, A. Levy, M. Korostishevsky, U. Nir, and E. Friedman Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women Int J Cancer 127 2010 589 597
    • (2010) Int J Cancer , vol.127 , pp. 589-597
    • Kontorovich, T.1    Levy, A.2    Korostishevsky, M.3    Nir, U.4    Friedman, E.5


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