-
1
-
-
68149182606
-
Functional targeting of the MUC1 oncogene in human cancers
-
Kufe D: Functional targeting of the MUC1 oncogene in human cancers. Cancer Biol Ther 8: 1201-1207, 2009.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1201-1207
-
-
Kufe, D.1
-
2
-
-
51049116003
-
MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells
-
Kawano T, Ahmad R, Nogi H, Agata N, Anderson K and Kufe D: MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells. Int J Oncol 33: 153-159, 2008.
-
(2008)
Int J Oncol
, vol.33
, pp. 153-159
-
-
Kawano, T.1
Ahmad, R.2
Nogi, H.3
Agata, N.4
Anderson, K.5
Kufe, D.6
-
3
-
-
0034655650
-
MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets
-
Dyomin VG, Palanisamy N, Lloyd KO, et al: MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets. Blood 95: 2666-2671, 2000.
-
(2000)
Blood
, vol.95
, pp. 2666-2671
-
-
Dyomin, V.G.1
Palanisamy, N.2
Lloyd, K.O.3
-
4
-
-
34748902247
-
The MUC1 and Galectin-3 Oncoproteins Function in a MicroRNA-Dependent Regulatory Loop
-
DOI 10.1016/j.molcel.2007.07.031, PII S1097276507005631
-
Ramasamy S, Duraisamy S, Barbashov S, Kawano T, Kharbanda S and Kufe D: The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop. Mol Cell 27: 992-1004, 2007. (Pubitemid 47488189)
-
(2007)
Molecular Cell
, vol.27
, Issue.6
, pp. 992-1004
-
-
Ramasamy, S.1
Duraisamy, S.2
Barbashov, S.3
Kawano, T.4
Kharbanda, S.5
Kufe, D.6
-
5
-
-
0041850346
-
Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
-
DOI 10.1038/sj.onc.1206732
-
Li Y, Liu D, Chen D, Kharbanda S and Kufe D: Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 22: 6107-6110, 2003. (Pubitemid 37175889)
-
(2003)
Oncogene
, vol.22
, Issue.38
, pp. 6107-6110
-
-
Li, Y.1
Liu, D.2
Chen, D.3
Kharbanda, S.4
Kufe, D.5
-
6
-
-
28544448610
-
MUC1 oncoprotein blocks glycogen synthase kinase 3β-mediated phosphorylation and degradation of β-catenin
-
DOI 10.1158/0008-5472.CAN-05-2474
-
Huang L, Chen D, Liu D, Yin L, Kharbanda S and Kufe D: MUC1 oncoprotein blocks GSK3β-mediated phosphorylation and degradation of β-catenin. Cancer Res 65: 10413-10422, 2005. (Pubitemid 41743735)
-
(2005)
Cancer Research
, vol.65
, Issue.22
, pp. 10413-10422
-
-
Huang, L.1
Chen, D.2
Liu, D.3
Yin, L.4
Kharbanda, S.5
Kufe, D.6
-
7
-
-
0030958706
-
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β- Catenin in cell adhesion
-
DOI 10.1074/jbc.272.19.12492
-
Yamamoto M, Bharti A, Li Y and Kufe D: Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion. J Biol Chem 272: 12492-12494, 1997. (Pubitemid 27203339)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.19
, pp. 12492-12494
-
-
Yamamoto, M.1
Bharti, A.2
Li, Y.3
Kufe, D.4
-
8
-
-
13844262819
-
Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response
-
Wei X, Xu H and Kufe D: Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. Cancer Cell 7: 167-178, 2005.
-
(2005)
Cancer Cell
, vol.7
, pp. 167-178
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
9
-
-
36749092728
-
MUC1 oncoprotein activates the IeκB kinase ß complex and constitutive NF-eκB signaling
-
Ahmad R, Raina D, Trivedi V, et al: MUC1 oncoprotein activates the IeκB kinase ß complex and constitutive NF-eκB signaling. Nat Cell Biol 9: 1419-1427, 2007.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1419-1427
-
-
Ahmad, R.1
Raina, D.2
Trivedi, V.3
-
10
-
-
70149111064
-
MUC1-C oncoprotein functions as a direct activator of the NF-kappaB p65 transcription factor
-
Ahmad R, Raina D, Joshi MD, Kawano T, Kharbanda S and Kufe D: MUC1-C oncoprotein functions as a direct activator of the NF-kappaB p65 transcription factor. Cancer Res 69: 7013-7021, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 7013-7021
-
-
Ahmad, R.1
Raina, D.2
Joshi, M.D.3
Kawano, T.4
Kharbanda, S.5
Kufe, D.6
-
11
-
-
34547092962
-
Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62
-
DOI 10.1074/jbc.M703222200
-
Leng Y, Cao C, Ren J, et al: Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin NUP62. J Biol Chem 282: 19321-19330, 2007. (Pubitemid 47100108)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.27
, pp. 19321-19330
-
-
Leng, Y.1
Cao, C.2
Ren, J.3
Huang, L.4
Chen, D.5
Ito, M.6
Kufe, D.7
-
12
-
-
30744474431
-
MUC1 oncoprotein stabilizes and activates estrogen receptor α
-
DOI 10.1016/j.molcel.2005.11.030, PII S1097276505019015
-
Wei X, Xu H and Kufe D: MUC1 oncoprotein stabilizes and activates estrogen receptor α. Mol Cell 21: 295-305, 2006. (Pubitemid 43099944)
-
(2006)
Molecular Cell
, vol.21
, Issue.2
, pp. 295-305
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
13
-
-
33847752147
-
Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene
-
Wei X, Xu H and Kufe D: Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene. Cancer Res 67: 1853-1858, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 1853-1858
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
14
-
-
10744220453
-
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
-
DOI 10.1016/S1535-6108(04)00020-0, PII S1535610804000200
-
Ren J, Agata N, Chen D, et al: Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents. Cancer Cell 5: 163-175, 2004. (Pubitemid 38283802)
-
(2004)
Cancer Cell
, vol.5
, Issue.2
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
Li, Y.4
Yu, W.-H.5
Huang, L.6
Raina, D.7
Chen, W.8
Kharbanda, S.9
Kufe, D.10
-
15
-
-
30044445260
-
MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90
-
DOI 10.1016/j.jpain.2006.01.060
-
Ren J, Bharti A, Raina D, Chen W, Ahmad R and Kufe D: MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-src and the molecular chaperone hsp90. Oncogene 25: 20-31, 2006. (Pubitemid 43050000)
-
(2006)
Oncogene
, vol.25
, Issue.1
, pp. 20-31
-
-
Ren, J.1
Bharti, A.2
Raina, D.3
Chen, W.4
Ahmad, R.5
Kufe, D.6
-
16
-
-
0042818006
-
Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress
-
Yin L and Kufe D: Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress. J Biol Chem 278: 35458-35464, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 35458-35464
-
-
Yin, L.1
Kufe, D.2
-
17
-
-
7944230166
-
MUC1 oncoprotein activates the Foxo3a transcription factor in a survival response to oxidative stress
-
Yin L, Huang L and Kufe D: MUC1 oncoprotein activates the Foxo3a transcription factor in a survival response to oxidative stress. J Biol Chem 279: 45721-45727, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 45721-45727
-
-
Yin, L.1
Huang, L.2
Kufe, D.3
-
18
-
-
33846994065
-
Mucin 1 oncoprotein blocks hypoxia-inducible factor 1 alpha activation in a survival response to hypoxia
-
Yin L, Kharbanda S and Kufe D: Mucin 1 oncoprotein blocks hypoxia-inducible factor 1 alpha activation in a survival response to hypoxia. J Biol Chem 282: 257-266, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 257-266
-
-
Yin, L.1
Kharbanda, S.2
Kufe, D.3
-
19
-
-
67649419014
-
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation
-
Yin L, Kharbanda S and Kufe D: MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation. Int J Oncol 34: 1691-1699, 2009.
-
(2009)
Int J Oncol
, vol.34
, pp. 1691-1699
-
-
Yin, L.1
Kharbanda, S.2
Kufe, D.3
-
20
-
-
51049090388
-
MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8
-
Agata N, Kawano T, Ahmad R, Raina D, Kharbanda S and Kufe D: MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8. Cancer Res 68: 6136-6144, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 6136-6144
-
-
Agata, N.1
Kawano, T.2
Ahmad, R.3
Raina, D.4
Kharbanda, S.5
Kufe, D.6
-
21
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP: MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233, 2009.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
22
-
-
65949121645
-
New tricks for animal microRNAs: Targeting of amino acid coding regions at conserved and non-conserved sites
-
Rigoutsos I: New tricks for animal microRNAs: targeting of amino acid coding regions at conserved and non-conserved sites. Cancer Res 69: 3245-3248, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 3245-3248
-
-
Rigoutsos, I.1
-
23
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
-
Filipowicz W, Bhattacharyya SN and Sonenberg N: Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight? Nat Rev Genet 9: 102-114, 2008.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
24
-
-
65349117527
-
MiRNAs and cancer
-
Visone R and Croce CM: MiRNAs and cancer. Am J Pathol 174: 1131-1138, 2009.
-
(2009)
Am J Pathol
, vol.174
, pp. 1131-1138
-
-
Visone, R.1
Croce, C.M.2
-
26
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M, et al: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99: 15524-15529, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
27
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, et al: A microRNA component of the p53 tumour suppressor network. Nature 447: 1130-1134, 2007.
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
-
28
-
-
35748961986
-
P53 enters the microRNA world
-
Hermeking H: P53 enters the microRNA world. Cancer Cell 12: 414-418, 2007.
-
(2007)
Cancer Cell
, vol.12
, pp. 414-418
-
-
Hermeking, H.1
-
29
-
-
64349101658
-
MicroRNA-125b is a novel negative regulator of p53
-
Le MT, Teh C, Shyh-Chang N, et al: MicroRNA-125b is a novel negative regulator of p53. Genes Dev 23: 862-876, 2009.
-
(2009)
Genes Dev
, vol.23
, pp. 862-876
-
-
Le, M.T.1
Teh, C.2
Shyh-Chang, N.3
-
30
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB and Bartel DP: Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20, 2005.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
31
-
-
34250805982
-
MicroRNA targeting specificity in mammals: Determinants beyond seed pairing
-
Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP and Bartel DP: MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27: 91-105, 2007.
-
(2007)
Mol Cell
, vol.27
, pp. 91-105
-
-
Grimson, A.1
Farh, K.K.2
Johnston, W.K.3
Garrett-Engele, P.4
Lim, L.P.5
Bartel, D.P.6
-
33
-
-
14044251458
-
Human microRNA targets
-
John B, Enright AJ, Aravin A, Tuschl T, Sander C and Marks DS: Human microRNA targets. PLoS Biol 2: e363, 2004.
-
(2004)
PLoS Biol
, vol.2
-
-
John, B.1
Enright, A.J.2
Aravin, A.3
Tuschl, T.4
Sander, C.5
Marks, D.S.6
-
35
-
-
33644750115
-
MiRBase: MicroRNA sequences, targets and gene nomenclature
-
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright AJ: MiRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34: D140-D144, 2006.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
Van Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
36
-
-
0035794196
-
A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells
-
Gaemers IC, Vos HL, Volders HH, van der Valk SW and Hilkens J: A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells. J Biol Chem 276: 6191-6199, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 6191-6199
-
-
Gaemers, I.C.1
Vos, H.L.2
Volders, H.H.3
Van Der Valk, S.W.4
Hilkens, J.5
-
37
-
-
75149124701
-
MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1
-
Sachdeva M and Mo YY: MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1. Cancer Res 70: 378-387, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 378-387
-
-
Sachdeva, M.1
Mo, Y.Y.2
-
38
-
-
77953178125
-
Mucin 1 oncoprotein expression is suppressed by the miR-125b oncomir
-
Rajabi H, Jin C, Ahmad R, McClary C and Kufe D: Mucin 1 oncoprotein expression is suppressed by the miR-125b oncomir. Genes & Cancer 1: 62-65, 2010.
-
(2010)
Genes & Cancer
, vol.1
, pp. 62-65
-
-
Rajabi, H.1
Jin, C.2
Ahmad, R.3
McClary, C.4
Kufe, D.5
-
39
-
-
25444520537
-
MiR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A, Calin GA, Fabbri M, et al: MiR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102: 13944-13949, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
-
41
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
DOI 10.1152/physrev.00013.2006
-
Kroemer G, Galluzzi L and Brenner C: Mitochondrial membrane permeabilization in cell death. Physiol Rev 87: 99-163, 2007. (Pubitemid 46209992)
-
(2007)
Physiological Reviews
, vol.87
, Issue.1
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
42
-
-
27244434788
-
A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
Calin GA, Ferracin M, Cimmino A, et al: A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 353: 1793 - 1801, 2005.
-
(2005)
N Engl J Med
, vol.353
, pp. 1793-1801
-
-
Calin, G.A.1
Ferracin, M.2
Cimmino, A.3
-
43
-
-
34548687035
-
Mir-29 regulates Mcl-1 protein expression and apoptosis
-
DOI 10.1038/sj.onc.1210436, PII 1210436
-
Mott JL, Kobayashi S, Bronk SF and Gores GJ: MiR-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 26: 6133-6140, 2007. (Pubitemid 47414372)
-
(2007)
Oncogene
, vol.26
, Issue.42
, pp. 6133-6140
-
-
Mott, J.L.1
Kobayashi, S.2
Bronk, S.F.3
Gores, G.J.4
|