Estrogen receptor β1 expression is regulated by miR-92 in breast cancer

Cancer Research

Volumn 70, Issue 11, 2010, Pages 4778-4784

  Al Nakhle, Hakeemah ^a   Burns, Philip A ^a   Cummings, Michele ^a   Hanby, Andrew M ^a   Hughes, Thomas A ^a   Satheesha, Sampoorna ^a   Shaaban, Abeer M ^a   Smith, Laura ^a   Speirs, Valerie ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR BETA; ESTROGEN RECEPTOR BETA 1; MESSENGER RNA; MICRORNA; MICRORNA 92; TAMOXIFEN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; BIOINFORMATICS; BREAST CANCER; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION;

3' UNTRANSLATED REGIONS; BINDING SITES; BREAST NEOPLASMS; CELL LINE, TUMOR; ESTRADIOL; ESTROGEN RECEPTOR BETA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; TAMOXIFEN;

EID: 77953157907     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-4104     Document Type: Article

References (32)

1. Fox EM, Davis RJ, Shupnik MA. ERβ in breast cancer - onlooker, passive player, or active protector? Steroids 2008;73:1039-1051
2. Leung YK, Mak P, Hassan S, Ho SM. Estrogen receptor (ER)-β isoforms: a key to understanding ERβ signaling. Proc Natl Acad Sci U S A 2006;103:13162-13167
3. Speirs V, Skliris GP, Burdall SE, et al. Distinct expression patterns of ERα and ERβ in normal human mammary gland. J Clin Pathol 2002;55:371-374
4. Treeck O, Lattrich C, Springwald A, et al. Estrogen receptor β exerts growth inhibitory effects on human mammary epithelial cells. Breast Cancer Res Treat 2010;120:557-565
5. Skliris GP, Munot K, Bell SM, et al. Reduced expression of oestrogen receptor β in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model. J Pathol 2003;201:213-220
6. Zhao C, Lam EW, Sunters A, et al. Expression of estrogen receptor β isoforms in normal breast epithelial cells and breast cancer: regulation by methylation. Oncogene 2003;22:7600-7606
7. Smith L, Brannan RA, Hanby AM, et al. Differential regulation of estrogen receptor β isoforms by 5′ untranslated regions in cancer. J Cell Mol Med. Epub 2009 Jul 28.
8. Breving K, Esquela-Kerscher A. The complexities of microRNA regulation: mirandering around the rules. Int J Biochem Cell Biol. Epub 2009 Sep 30.
9. Verghese ET, Hanby AM, Speirs V, et al. Small is beautiful: microRNAs and breast cancer - where are we now? J Pathol 2008;215:214-221
10. Iorio MV, Ferracin M, Liu CG, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005;65:7065-7070
11. Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009;136:215-233
12. Kondo N, Toyama T, Sugiura H, et al. miR-206 expression is down-regulated in estrogen receptor α-positive human breast cancer. Cancer Res 2008;68:5004-5008
13. Adams BD, Furneaux H, White BA. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α (ERα) and represses ERα messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 2007;21:1132-1147
14. Si ML, Zhu S, Wu H, et al. miR-21-mediated tumor growth. Oncogene 2007;26:2799-2803
15. Lowery AJ, Miller N, Devaney A, et al. MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer. Breast Cancer Res 2009;11:R27.
16. He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature 2005;435:828-833
17. Diosdado B, van de Wiel MA, Terhaar Sive Droste JS, et al. MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br J Cancer 2009;101:707-714
18. Mu P, Han YC, Betel D, et al. Genetic dissection of the miR-17-92 cluster of microRNAs in Myc-induced B-cell lymphomas. Genes Dev 2009;23:2806-2811
19. Olive V, Bennett MJ, Walker JC, et al. miR-19 is a key oncogenic component of mir-17-92. Genes Dev 2009;23:2839-2849
20. Shaaban AM, Green AR, Karthik S, et al. Nuclear and cytoplasmic expression of ERβ1, ERβ2, and ERβ5 identifies distinct prognostic outcome for breast cancer patients. Clin Cancer Res 2008;14:5228-5235
21. Maraqa L, Cummings M, Peter MB, et al. Carcinoembryonic antigen cell adhesion molecule 6 predicts breast cancer recurrence following adjuvant tamoxifen. Clin Cancer Res 2008;14:405-411
22. Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell 2008;133:217-222
23. Sempere LF, Christensen M, Silahtaroglu A, et al. Altered microRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res 2007;67:11612-11620
24. Kovalchuk O, Tryndak VP, Montgomery B, et al. Estrogen-induced rat breast carcinogenesis is characterised by alterations in DNA methylation, histone modifications and aberrant microRNA expression. Cell Cycle 2007;6:2010-2018
25. Klinge CM. Estrogen regulation of microRNA expression. Curr Genomics 2009;10:169-183
26. Maillot G, Lacroix-Triki M, Pierredon S, et al. Widespread estrogen-dependent repression of microRNAs involved in breast tumor cell growth. Cancer Res 2009;69:8332-8340
27. Leivonen SK, Mäkelä R, Ostling P, et al. Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines. Oncogene 2009;28:3926-3936
28. Landgraf P, Rusu M, Sheridan R, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007;129:1401-1414
29. Burdall SE, Hanby AM, Lansdown MR, Speirs V. Breast cancer cell lines: friend or foe? Breast Cancer Res 2003;5:89-95.
30. Hartman J, Lindberg K, Morani A, et al. Estrogen receptor β inhibits angiogenesis and growth of T47D breast cancer xenografts. Cancer Res 2006;66:11207-11213
31. Hartman J, Edvardsson K, Lindberg K, et al. Tumor repressive functions of estrogen receptor β in SW480 colon cancer cells. Cancer Res 2009;69:6100-6106
32. Castellano L, Giamas G, Jacob J, et al. The estrogen receptor-α- induced microRNA signature regulates itself and its transcriptional response. Proc Natl Acad Sci U S A 2009;106:15732-15737