Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1β (IL-1β) in astrocyte cultures

Journal of Neuroimmunology

Volumn 174, Issue 1-2, 2006, Pages 63-73

  Zhang, Wandong ^a,b   Petrovic, Jelena Mojsilovic ^a   Callaghan, Debbie ^a   Jones, Aimee ^a   Cui, Hong ^a   Howlett, Clare ^a   Stanimirovic, Danica ^a,b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Astrocytes; HIF 1 ; Hypoxia; IL 1

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CADMIUM CHLORIDE; HYPOXIA INDUCIBLE FACTOR 1; INTERLEUKIN 1BETA; MESSENGER RNA; OLIGONUCLEOTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BINDING SITE; BRAIN HYPOXIA; CONTROLLED STUDY; CYTOKINE PRODUCTION; FETUS; GENE CONTROL; GENETIC TRANSFECTION; GENOTYPE; HETEROZYGOSITY; HUMAN; HUMAN CELL; MOUSE; NERVE CELL CULTURE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; REPORTER GENE; STRUCTURAL HOMOLOGY; TRANSACTIVATION; TRANSCRIPTION INITIATION; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIMUTAGENIC AGENTS; ASTROCYTES; BLOTTING, WESTERN; CELL HYPOXIA; COBALT; CYSTEINE PROTEINASE INHIBITORS; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FETUS; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INTERLEUKIN-1; LEUPEPTINS; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MUTAGENESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33646117271     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2006.01.014     Document Type: Article

References (48)

1. Auron P.E. The interleukin-1 receptor: ligand interactions and signal transduction. Cytokine Growth Factor Rev. 9 (1998) 221-237
2. Basu A., Krady J.K., and Levison S.W. Interleukin-1: a master regulator of neuroinflammation. J. Neurosci. Res. 78 (2004) 151-156
3. Boutin H., LeFeuvre R.A., Horai R., Asano M., Iwakura Y., and Rothwell N.J. Role of IL-1α and IL-1β in ischemic brain damage. J. Neurosci. 21 (2001) 5528-5534
4. Bergeron M., Yu A.Y., Solway K.E., Semenza G.L., and Sharp F.R. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischemia in rat brain. Eur. J. Neurosci. 11 (1999) 4159-4170
5. Carmeliet P., Dor Y., Herbert J.M., Fukumura D., Brusselmans K., Dewerchin M., Neeman M., Bono F., Abramovitch R., Maxwell P., Koch C.J., Ratcliffe P., Moons L., Jain R.K., Collen D., Keshert E., and Keshert E. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394 (1998) 485-490
6. Colotta F., Ghezzi P., and Mantovani A. Interleukin-1. In: Mire-Sluis A., and Thrope R. (Eds). Cytokines (1998), Academic Press, San Diego 1-18
7. Haqqani A.S., Nesic M., Preston E., Baumann E., Kelly J., and Stanimirovic D. Characterization of vascular protein expression patterns in cerebral ischemia/reperfusion using laser capture microdissection and ICAT-nanoLC-MS/MS. FASEB J. 19 (2005) 1809-1821
8. Herdegen T., and Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Kros, and CRIB/ATF protein. Brain Res. Rev. 28 (1998) 370-490
9. Hill J.K., Gunion-Rinker L., Kulhanek D., Lessov N., Kim S., Clark W.M., Dixon M.P., Nishi R., Stenzel-Poore M.P., and Eckenstein F.P. Temporal modulation of cytokine expression following focal cerebral ischemia in mice. Brain Res. 820 (1999) 45-54
10. Hu X., Nesic-Taylor O., Qiu J., Rea H.C., Babian R., Rassin D.K., and Regino P.-P. Activation of nuclear factor-κB signaling pathway by interleukin-1 after hypoxia/ischemia in neonatal rat hippocampus and cortex. J. Neurochem. 93 (2005) 26-37
11. Huang F.P., Wang Z.Q., Wu D.C., Schielke G.P., Sun Y., and Yang G.Y. Early NFκB activation is inhibited during focal cerebral ischemia in interleukin-1β-converting enzyme deficient mice. J. Neurosci. Res. 73 (2003) 698-707
12. Jander S., Schroeter M., Peters O., Witte O.W., and Stoll G. Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain. J. Cereb. Blood Flow Metab. 21 (2001) 218-225
13. Jeong H.J., Chung H.S., Lee B.R., Kim S.J., Yoo S.J., Hong S.H., and Kim H.M. Expression of proinflammatory cytokines via HIF-1α and NF-κB activation on desferrioxamine-stimulated HMC-1 cells. Biochem. Biophys. Res. Commun. 306 (2003) 805-811
14. Jung Y.J., Isaacs J.S., Lee S., Trepel J., and Neckers L. IL-1β-mediated up-regulation of HIF-1α via an NFκB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J. 17 (2003) 2115-2117
15. Kallio P.J., Wilson W.J., O'Brien S., Makino Y., and Poellinger L. Regulation of the hypoxia-inducible transcription factor-1α by the ubiquitin-proteasome pathway. J. Biol. Chem. 274 (1999) 6519-6525
16. Lau L.T., and Yu A.C. Astrocytes produce and release interleukin-1, interleukin-6, tumor necrosis factor alpha and interferon-gamma following traumatic and metabolic injury. J. Neurotrauma 18 (2001) 351-359
17. Morganti-Kossmann M.C., Rancan M., Otto V.I., Stahel P.F., and Kossmann T. Role of cerebral inflammation after traumatic brain injury: a revisited concept. Shock 16 (2001) 165-177
18. Muruganandam A., Herx L.M., Monette R., Durkin J.P., and Stanimirovic D.B. Development of immortalized human cerebromicrovascular endothelial cell line as an in vitro model of the human blood-brain barrier. FASEB J. 11 (1997) 1187-1197
19. Nadjar A., Combe C., Laye S., Tridon V., Dantzer R., Amedee T., and Parnet P. Nuclear factor κB nuclear translocation as a crucial marker of brain response to interleukin-1. A study in rat and interleukin-1 type I deficient mouse. J. Neurochem. 87 (2003) 1024-1036
20. Naldini A., and Carraro F. Role of inflammatory mediators in angiogenesis. Curr. Drug Targets Inflamm. Allergy 4 (2005) 3-8
21. Palmer L.A., Semenza G.L., Stoler M.H., and Johns R.A. Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1. Am. J. Physiol. 274 (1998) L212-L219 (Lung Cell. Mol. Physiol. 18)
22. Peterson G.L. A simplification of the protein assay method of Lowry et al. Which is more generally applicable. Anal. Biochem. 83 (1977) 346-356
23. Saliba E., and Henrot A. Inflammatory mediators and neonatal brain damage. Biol. Neonate 79 (2001) 224-227
24. Salminen A., Liu P.K., and Hsu C.Y. Alteration of transcription factor binding activities in the ischemic rat brain. Biochem. Biophys. Res. Comm. 212 (1995) 932-944
25. Scharte M., Han X., Bertges D.J., Fink M.P., and Delude R.L. Cytokines induce HIF-1 DNA binding and the expression of HIF-1-dependent genes in cultured rat enterocytes. Am. J. Physiol.: Gasterointest. Liver Physiol. 284 (2003) G373-G384
26. Schousboe A., Booher J., and Hertz L. Content of ATP in cultivated neurons and astrocytes exposed to balanced and potassium-rich media. J. Neurochem. 17 (1970) 1501-1504
27. Semenza G.L. Hypoxia-inducible factor 1: from molecular biology to cardiopulmonary physiology. Chest 114 (1998) 40S-45S
28. 2 homeostasis by hypoxia-inducible factor 1. Annu. Rev. Cell Dev. Biol. 15 (1999) 551-578
29. Semenza G.L. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology 19 (2004) 176-182
30. Semenza G.L., Jiang B.H., Leung S.W., Passantino R., Concordet J.P., Maire P., and Giallongo A. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J. Biol. Chem. 271 (1996) 32529-32537
31. Stanimirovic D.B. Inflammatory activation of brain cells by hypoxia: transcription factors and signaling pathway. In: Feuerstein G.Z. (Ed). Inflammation and Stroke (2001), Birkhauser Verlag Basel, Switzerland 101-111
32. Stanimirovic D., and Satoh K. Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation. Brain Pathol. 10 (2000) 113-126
33. Stanimirovic D., Shapiro A., Wong J., Hutchison J., and Durkin J. The induction of ICAM-1 in human cerebromicrovascular endothelial cells (HCEC) by ischemia-like conditions promotes enhanced neutrophil/HCEC adhesion. J. Neuroimmunol. 76 (1997) 193-205
34. Stanimirovic D., Zhang W., Howlett C., Lemieux P., and Smith C. Inflammatory gene transcription in human astrocytes exposed to hypoxia: roles of the nuclear factor-κB and autocrine stimulation. J. Neuroimmunol. 119 (2001) 365-376
35. Stephenson D., Yin T., Smalstig E.B., Hsu M.A., Panetta J., Little S., and Clemens J. Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 20 (2000) 592-603
36. Stoll G., Jander S., and Schroeter M. Cytokines in CNS disorders: neurotoxicity versus neuroprotection. J. Neural Transm., Suppl. 59 (2000) 81-89
37. Stoll G., Jander S., and Schroeter M. Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system. Adv. Exp. Med. Biol. 513 (2002) 87-113
38. Wang G.L., and Semenza G.L. Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J. Biol. Chem. 268 (1993) 21513-21518
39. Wang G.L., and Semenza G.L. General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 4304-4308
40. Wang G.L., and Semenza G.L. Purification and characterization of hypoxia-inducible factor 1. J. Biol. Chem. 270 (1995) 1230-1237
41. Wang X., Li X., Currie R.W., Willette R.N., Barone F.C., and Feuerstein G.Z. Application of real-time polymerase chain reaction to quantitate induced expression of interleukin-1β mRNA in ischemic brain tolerance. J. Neurosci. Res. 59 (2000) 238-246
42. Wen Y., Yang S., Liu R., Perez E., Yi K.D., Koulen P., and Simpkins J.W. Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia. Brain Res. 1008 (2004) 147-154
43. Yang D.I., Chen S.D., Yang Y.T., Ju T.C., Xu J.M., and Hsu C.Y. Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1. Br. J. Pharmacol. 141 (2004) 988-996
44. Yong V.W., Tejada-Berges T., Goodyear C.G., Antel J.P., and Yong F.P. Differential proliferative responses of human and mouse astrocytes to gamma interferon. Glia 6 (1992) 269-280
45. Zhang W., and Stanimirovic D. Current and future therapeutic strategies to target inflammation in stroke. Curr. Drug Targets Inflamm. Allergy 1 (2002) 151-166
46. Zhang W., Smith C., Shiparo A., Monette R., Hutchison J., and Stanimirovic D. Increased expression of bioactive chemokines in human cerebromicrovascular endothelial cells and astrocytes subjected to simulated ischemia in vitro. J. Neuroimmunol. 101 (1999) 148-160
47. Zhang W., Smith C., Howlett C., and Stanimirovic D. Inflammatory activation of human brain endothelial cells by hypoxic astrocytes in vitro is mediated by IL-1β. J. Cereb. Blood Flow Metab. 20 (2000) 967-978
48. Zhang W., Mojsilovic-Petrovic J., Andrade M., Zhang H., Ball M., and Stanimirovic D. Expression and functional characterization of ABCG2 in brain endothelial cells and vessels. FASEB J. 17 (2003) 2085-2087