CCAAT/enhancer binding protein β is a neuronal transcriptional regulator activated by nerve growth factor receptor signaling

Journal of Neurochemistry

Volumn 70, Issue 6, 1998, Pages 2424-2433

  Sterneck, Esta ^a   Johnson, Peter F ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Brain; CCAAT enhancer binding protein ; Mitogen activated protein kinase site mutation; Nerve growth factor; PC12 cells; Trk tyrosine kinase receptor

Indexed keywords

BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; ENHANCER REGION; ENZYME PHOSPHORYLATION; MOUSE; NERVE GROWTH; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0031775944     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70062424.x     Document Type: Article

References (46)

1. Alberini C. M., Ghirardi M., Metz R., and Kandel E. R. (1994) C/ EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia. Cell 76, 1099-1114.
2. Ausubel F. M., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith J. A., and Kruhl K., eds (1995) Current Protocols in Molecular Biology. Greene Publishing and Wiley-Interscience, New York.
3. Cardinaux J.-R. and Magistretti P. J. (1996) Vasoactive intestinal peptide, pituitary adenylate cyclase-activating peptide, and nor-adrenalin induce the transcription factor CCAAT/enhancer binding protein (C/EBP)-β and C/EBPδ in mouse cortical astrocytes: involvement in cAMP-regulated glycogen metabolism. J. Neurosci. 16, 919-929.
4. Chang C. J., Shen B. J., and Lee S. C. (1995) Autoregulated induction of the acute-phase response transcription factor gene, agp/ ebp. DNA Cell Biol. 14, 529-537.
5. Descombes P. and Schibler U. (1991) A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 67, 569-579.
6. Desmarais D., Filion M., Lapointe L., and Royal A. (1992) Cell-specific transcription of the peripherin gene in neuronal cell lines involves a cis-acting element surrounding the TATA box. EMBO J. 11, 2971-2980.
7. Fujita K., Lazarovici P., and Guroff G. (1989) Regulation of the differentiation of PC12 pheochromocytoma cells. Environ. Health Perspect. 80, 127-142.
8. Greene L. A. and Tischler A. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.
9. Halegoua S., Armstrong R. C., and Kremer N. E. (1991) Dissecting the mode of action of a neuronal growth factor. Curr. Top. Microbiol. Immunol 165, 119-170.
10. Hempstead B. L., Rabin S. J., Kaplan L., Reid S., Parada L. F., and Kaplan D. R. (1992) Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation. Neuron 9, 883-896.
11. Jamaluddin M., Garofalo R., Orga L., and Brasier A. R. (1996) Inducible translational regulation of the NF-IL6 transcription factor by respiratory syncytial virus infection in pulmonary epithelial cells. J. Virol. 70, 1554-1563.
12. Johnson P. F. and Williams C. W. (1994) CCAAT/enhancer binding (C/EBP) proteins, in Liver Gene Expression (Yaniv M. and Tronche F., eds), pp. 231-258. Raven Press, New York.
13. Jones K. R., Farinas I., Backus C., and Reichardt L. F. (1994) Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76, 989-999.
14. Kang H. J. and Schuman E. M. (1995) Neurotrophin-induced modulation of synaptic transmission in the adult hippocampus. J. Physiol. 89, 11-22.
15. Kaplan D. R. and Stephens R. M. (1994) Neurotrophin signal transduction by the Trk receptor. J. Neurobiol. 25, 1404-1417.
16. Katz S., Kowenz-Leutz E., Müller C., Meese K., Ness S. A., and Leutz A. (1993) The NF-M transcription factor is related to C/ EBP-β and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells. EMBO J. 12, 1321-1332.
17. Korsching S. (1993) The neurotrophic factor concept: a reexamination. J. Neurosci. 13, 2739-2748.
18. Korte M., Carroll P., Wolf E., Brem G., Thoenen H., and Bonhoeffer T. (1995) Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc. Natl. Acad. Sci. USA 92, 8856-8860.
19. Kowenz-Leutz E., Twamley G., Ansieau S., and Leutz A. (1994) Novel mechanism of C/EBP β (NF-M) transcriptional control: activation through derepression. Genes Dev. 8, 2781-2791.
20. Lee Y. H., Williams S. C., Baer M., Sterneck E., Gonzalez F. J., and Johnson P. F. (1997) The ability of C/EBP beta but not C/ EBP alpha to synergize with an SpI protein is specified by the leucine zipper and activation domain. Mol. Cell. Biol 17, 2038-2047.
21. Leonard D. G., Gorham J. D., Cole P., Greene L. A., and Ziff E. B. (1988) A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein. J. Cell Biol. 106, 181-193.
22. Lincoln A. J., Monczak Y., Williams S. C., and Johnson P. F. (1998) Inhibition of C/EPBα and C/EBPβ translation by upstream open reading frames. J. Biol. Chem. (in press).
23. Lopez-Rodriguez C., Botella L., and Corbi A. L. (1997) CCAAT-enhancer-binding proteins (C/EBP) regulate the tissue specific activity of the CD11c integrin gene promoter through functional interactions with Sp1 proteins. J. Biol. Chem. 272, 29120-29126.
24. Metz R. and Ziff E. (1991) cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription. Genes Dev. 5, 1754-1766.
25. Minichiello L. and Klein R. (1996) TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons. Genes Dev. 10, 2849-2858.
26. Nakajima T., Kinoshita S., Sasagawa T., Sasaki K., Naruto M., Kishimoto T., and Akira S. (1993) Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6. Proc. Natl. Acad. Sci. USA 90, 2207-2211.
27. Niehof M., Manns M. P., and Trautwein C. (1997) CREB controls LAP/C/EBPβ transcription. Mol. Cell. Biol. 17, 3600-3613.
28. Nordeen S. K. (1988) Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6, 454-457.
29. Oelschlager M., Janknecht R., Krieg J., Schreek S., and Lüscher B. (1996) Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M. EMBO J. 15, 2771-2780.
30. Patterson S. L., Abel T., Deuel T. A., Martin K. C., Rose J. C. and Kandel E. R. (1996) Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 16, 1137-1145.
31. Plumb M., Frampton J., Wainwright H., Walker M., Macleod K., Goodwin G., and Harrison P. (1989) GATAAG; a cis-control region binding an erythroid-specific nuclear factor with a role in globin and non-globin gene expression. Nucleic Acids Res. 17, 73-92.
32. Sambucetti L. C., Schaber M., Kramer R., Crowl R., and Curran T. (1986) The fos gene product undergoes extensive post-translational modification in eukaryotic but not in prokaryotic cells. Gene 43, 69-77.
33. -/- mice reveals a role for neurotrophins in CNS patterning. Neuron 19, 269-281.
34. Screpanti I., Romani L., Musiani P., Modesti A., Fattori E., Lazzaro D., Sellitto C., Scarpa S., Bellavia D., Lattanzio G., Bistoni F., Frati L., Cortese R., Gulino A., Ciliberto G., Costantini F., and Poli V. (1995) Lymphoproliferative disorder and imbalanced T-helper response in C/EBPβ-deficient mice. EMBO J. 14, 1932-1941.
35. Segal R. A. and Greenberg M. E. (1996) Intracellular signaling pathways activated by neurotrophic factors. Annu. Rev. Neurosci. 19, 463-489.
36. Sirois J. and Richards J. S. (1993) Transcriptional regulation of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells Evidence for the role of a cis-acting C/EBPβ promoter element. J. Biol. Chem. 268, 21931-21938.
37. Snider W. D. (1994) Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77, 627-638.
38. Soledad A., Frisén J., del Rio J. A., Soriano E., Barbacid M., and Silos-Santiago I. (1997) TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death. J. Neurosci. 17, 3623-3633.
39. Sterneck E., Müller C., Katz S., and Leutz A. (1992) Autocrine growth induced by kinase type oncogenes in mycloid cells requires AP-1 and NF-M, a myeloid specific, C/EBP-like factor. EMBO J. 11, 115-126.
40. Sterneck E., Kaplan D. R., and Johnson P. F. (1996) Interleukin-6 induces expression of peripherin and cooperates with Trk receptor signaling to promote neuronal differentiation in PC12 cells. J. Neurochem. 67, 1365-1374.
41. Sterneck E., Tessarollo L., and Johnson P. F. (1997) An essential role for C/EBPβ in female reproduction. Genes Dev. 11, 2153-2162.
42. Tanaka T., Akira S., Yoshida K., Umemoto M., Yoneda Y., Shirafuji N., Fujiwara H., Suematsu S., Yoshida N., and Kishimoto T. (1995) Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell 80, 353-361.
43. Tessarollo L. and Parada L. F. (1995) Oncogene techniques: in situ hybridization, in Methods in Enzymology, Vol. 254 (Verma I. M. and Vogt P. K., eds). pp. 419-430. Academic Press, San Diego.
44. Williams S. C., Cantwell C. A., and Johnson P. F. (1991) A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. Genes Dev. 5, 1553-1567.
45. Williams S. C., Baer M., Dillner A. J., and Johnson P. F. (1995) CRP2 (C/EBPβ) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity. EMBO J. 14, 3170-3183.
46. Yano S., Fukunaga K., Takiguchi M., Ushio Y., Mori M., and Miyamoto E. (1996) Regulation of CCAAT/enhancer-binding protein family members by stimulation of glutamate receptors in cultured rat cortical astrocytes. J. Biol. Chem. 271, 23520-23527.