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Volumn 11, Issue , 2011, Pages

Role and expression of FRS2 and FRS3 in prostate cancer

Author keywords

Adaptor proteins; Fgf signalling; Frs2; Frs3; Prostate cancer

Indexed keywords

ADAPTOR PROTEIN; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 2; FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 3; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; FRS2 PROTEIN, HUMAN; FRS3 PROTEIN, HUMAN; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR PROTEIN;

EID: 81055149761     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-484     Document Type: Article
Times cited : (19)

References (40)
  • 1
    • 75149170979 scopus 로고    scopus 로고
    • Fibroblast Growth Factors. From development to cancer
    • 10.1038/nrc2780, 20094046
    • Turner N, Grose R. Fibroblast Growth Factors. From development to cancer. Nat Rev Cancer 2010, 10:116-129. 10.1038/nrc2780, 20094046.
    • (2010) Nat Rev Cancer , vol.10 , pp. 116-129
    • Turner, N.1    Grose, R.2
  • 2
    • 72049092008 scopus 로고    scopus 로고
    • De-regulated FGF receptors as therapeutic targets in cancer
    • 10.1016/j.pharmthera.2009.10.001, 19874848
    • Knights V, Cook SJ. De-regulated FGF receptors as therapeutic targets in cancer. Pharmacol Ther 2010, 125:105-117. 10.1016/j.pharmthera.2009.10.001, 19874848.
    • (2010) Pharmacol Ther , vol.125 , pp. 105-117
    • Knights, V.1    Cook, S.J.2
  • 3
    • 78049510048 scopus 로고    scopus 로고
    • Expression and functional role of negative signalling regulators in tumour development and progression
    • 10.1002/ijc.25542, 20607827
    • Murphy T, Hori S, Sewell J, Gnanapragasam VJ. Expression and functional role of negative signalling regulators in tumour development and progression. Int J Cancer 2010, 127:2491-2499. 10.1002/ijc.25542, 20607827.
    • (2010) Int J Cancer , vol.127 , pp. 2491-2499
    • Murphy, T.1    Hori, S.2    Sewell, J.3    Gnanapragasam, V.J.4
  • 5
    • 34548434816 scopus 로고    scopus 로고
    • Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer
    • 10.1002/path.2205, 17607666
    • Sahadevan K, Darby S, Leung HY, Mathers ME, Robson CN, Gnanapragasam VJ. Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer. J Pathol 2007, 213:82-90. 10.1002/path.2205, 17607666.
    • (2007) J Pathol , vol.213 , pp. 82-90
    • Sahadevan, K.1    Darby, S.2    Leung, H.Y.3    Mathers, M.E.4    Robson, C.N.5    Gnanapragasam, V.J.6
  • 6
    • 76749136307 scopus 로고    scopus 로고
    • Evidence for distinct alterations in the FGF axis in prostate cancer progression to an aggressive clinical phenotype
    • Murphy T, Darby S, Mathers ME, Gnanapragasam VJ. Evidence for distinct alterations in the FGF axis in prostate cancer progression to an aggressive clinical phenotype. J Pathol 2010, 220:452-460.
    • (2010) J Pathol , vol.220 , pp. 452-460
    • Murphy, T.1    Darby, S.2    Mathers, M.E.3    Gnanapragasam, V.J.4
  • 7
    • 0030665570 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells
    • Feng S, Wang F, Matsubara A, Kan M, McKeehan WL. Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells. Cancer Research 1997, 57:5369-5378.
    • (1997) Cancer Research , vol.57 , pp. 5369-5378
    • Feng, S.1    Wang, F.2    Matsubara, A.3    Kan, M.4    McKeehan, W.L.5
  • 8
    • 0141885098 scopus 로고    scopus 로고
    • Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal regulated kinase activation, and in vivo proliferation
    • Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal regulated kinase activation, and in vivo proliferation. Cancer Res 2003, 63:6237-6243.
    • (2003) Cancer Res , vol.63 , pp. 6237-6243
    • Freeman, K.W.1    Gangula, R.D.2    Welm, B.E.3    Ozen, M.4    Foster, B.A.5    Rosen, J.M.6    Ittmann, M.7    Greenberg, N.M.8    Spencer, D.M.9
  • 9
    • 0032540941 scopus 로고    scopus 로고
    • Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins
    • 10.1074/jbc.273.29.17987, 9660748
    • Xu H, Lee KW, Goldfarb M. Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins. J Biol Chem 1998, 273:17987-17990. 10.1074/jbc.273.29.17987, 9660748.
    • (1998) J Biol Chem , vol.273 , pp. 17987-17990
    • Xu, H.1    Lee, K.W.2    Goldfarb, M.3
  • 10
    • 70349776060 scopus 로고    scopus 로고
    • FGF-receptor substrate 2 functions as a molecular sensor integrating external regulatory signals into the FGF pathway
    • 10.1038/cr.2009.95, 19652666
    • Zhou W, Feng X, Wu Y, Benge J, Zhang Z, Chen Z. FGF-receptor substrate 2 functions as a molecular sensor integrating external regulatory signals into the FGF pathway. Cell Res 2009, 19:1165-11677. 10.1038/cr.2009.95, 19652666.
    • (2009) Cell Res , vol.19 , pp. 1165-11677
    • Zhou, W.1    Feng, X.2    Wu, Y.3    Benge, J.4    Zhang, Z.5    Chen, Z.6
  • 11
    • 0036672917 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor-induced signalling
    • Stoletov KV, Ratcliffe KE, Terman BI. Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor-induced signalling. Faseb J 2002, 16:1283-1285.
    • (2002) Faseb J , vol.16 , pp. 1283-1285
    • Stoletov, K.V.1    Ratcliffe, K.E.2    Terman, B.I.3
  • 12
    • 0034967978 scopus 로고    scopus 로고
    • Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signalling cascade
    • 10.1128/MCB.21.13.4177-4187.2001, 87079, 11390647
    • Melillo RM, Santoro M, Ong SH, Billaud M, Fusco A, Hadari YR, Schlessinger J, Lax I. Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signalling cascade. Mol Cell Biol 2001, 21:4177-4187. 10.1128/MCB.21.13.4177-4187.2001, 87079, 11390647.
    • (2001) Mol Cell Biol , vol.21 , pp. 4177-4187
    • Melillo, R.M.1    Santoro, M.2    Ong, S.H.3    Billaud, M.4    Fusco, A.5    Hadari, Y.R.6    Schlessinger, J.7    Lax, I.8
  • 13
    • 0030706168 scopus 로고    scopus 로고
    • A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signalling pathway
    • 10.1016/S0092-8674(00)80252-4, 9182757
    • Kouhara H, Hadari YR, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I, Schlessinger J. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signalling pathway. Cell 1997, 89:693-702. 10.1016/S0092-8674(00)80252-4, 9182757.
    • (1997) Cell , vol.89 , pp. 693-702
    • Kouhara, H.1    Hadari, Y.R.2    Spivak-Kroizman, T.3    Schilling, J.4    Bar-Sagi, D.5    Lax, I.6    Schlessinger, J.7
  • 14
    • 0033515534 scopus 로고    scopus 로고
    • The signalling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation
    • 10.1074/jbc.274.14.9861, 10092678
    • Meakin SO, MacDonald JI, Gryz EA, Kubu CJ, Verdi JM. The signalling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation. J Biol Chem 1999, 274:9861-9870. 10.1074/jbc.274.14.9861, 10092678.
    • (1999) J Biol Chem , vol.274 , pp. 9861-9870
    • Meakin, S.O.1    MacDonald, J.I.2    Gryz, E.A.3    Kubu, C.J.4    Verdi, J.M.5
  • 15
    • 33646536597 scopus 로고    scopus 로고
    • Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3
    • 10.1016/j.bbamcr.2006.02.009, 16697063
    • Dixon SJ, MacDonald JI, Robinson KN, Kubu CJ, Meakin SO. Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3. Biochim Biophys Acta 2006, 1763:366-380. 10.1016/j.bbamcr.2006.02.009, 16697063.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 366-380
    • Dixon, S.J.1    MacDonald, J.I.2    Robinson, K.N.3    Kubu, C.J.4    Meakin, S.O.5
  • 17
    • 0035902581 scopus 로고    scopus 로고
    • Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways
    • 10.1073/pnas.161259898, 37478, 11447289
    • Hadari YR, Gotoh N, Kouhara H, Lax I, Schlessinger J. Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways. Proc Natl Acad Sci USA 2001, 98:8578-8583. 10.1073/pnas.161259898, 37478, 11447289.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8578-8583
    • Hadari, Y.R.1    Gotoh, N.2    Kouhara, H.3    Lax, I.4    Schlessinger, J.5
  • 18
    • 1842850649 scopus 로고    scopus 로고
    • FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts
    • 10.1016/S0014-5793(04)00287-X, 15094036
    • Gotoh N, Laks S, Nakashima M, Lax I, Schlessinger J. FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts. FEBS Lett 2004, 564:14-18. 10.1016/S0014-5793(04)00287-X, 15094036.
    • (2004) FEBS Lett , vol.564 , pp. 14-18
    • Gotoh, N.1    Laks, S.2    Nakashima, M.3    Lax, I.4    Schlessinger, J.5
  • 19
    • 77952955054 scopus 로고    scopus 로고
    • FRS2β, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding
    • 10.1038/onc.2010.69, 20228838
    • Iejima D, Minegishi Y, Takenaka K, Siswanto A, Watanabe M, Huang L, Watanabe T, Tanaka F, Kuroda M, Gotoh N. FRS2β, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding. Oncogene 2010, 29:3087-3099. 10.1038/onc.2010.69, 20228838.
    • (2010) Oncogene , vol.29 , pp. 3087-3099
    • Iejima, D.1    Minegishi, Y.2    Takenaka, K.3    Siswanto, A.4    Watanabe, M.5    Huang, L.6    Watanabe, T.7    Tanaka, F.8    Kuroda, M.9    Gotoh, N.10
  • 20
    • 33750214274 scopus 로고    scopus 로고
    • Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signalling pathways
    • 10.1038/sj.onc.1209656, 16702953
    • Huang L, Watanabe M, Chikamori M, Kido Y, Yamamoto T, Shibuya M, Gotoh N, Tsuchida N. Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signalling pathways. Oncogene 2006, 25:6457-6466. 10.1038/sj.onc.1209656, 16702953.
    • (2006) Oncogene , vol.25 , pp. 6457-6466
    • Huang, L.1    Watanabe, M.2    Chikamori, M.3    Kido, Y.4    Yamamoto, T.5    Shibuya, M.6    Gotoh, N.7    Tsuchida, N.8
  • 21
    • 75149130163 scopus 로고    scopus 로고
    • The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons
    • 10.1111/j.1471-4159.2009.06503.x, 19943849
    • Hryciw T, MacDonald JI, Phillips R, Seah C, Pasternak S, Meakin SO. The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons. J Neurochem 2010, 112:924-939. 10.1111/j.1471-4159.2009.06503.x, 19943849.
    • (2010) J Neurochem , vol.112 , pp. 924-939
    • Hryciw, T.1    MacDonald, J.I.2    Phillips, R.3    Seah, C.4    Pasternak, S.5    Meakin, S.O.6
  • 22
    • 0037372082 scopus 로고    scopus 로고
    • The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins
    • 10.1210/en.2002-221002, 12586769
    • Ranzi V, Meakin SO, Miranda C, Mondellini P, Pierotti MA, Greco A. The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins. Endocrinology 2003, 144:922-928. 10.1210/en.2002-221002, 12586769.
    • (2003) Endocrinology , vol.144 , pp. 922-928
    • Ranzi, V.1    Meakin, S.O.2    Miranda, C.3    Mondellini, P.4    Pierotti, M.A.5    Greco, A.6
  • 23
    • 0032575135 scopus 로고    scopus 로고
    • Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells
    • 10.1038/sj.onc.1201802, 9652746
    • Carter S, Auer KL, Reardon DB, Birrer M, Fisher PB, Valerie K, Scmidtt-Ullrich R, Mikkelsen R, Dent P. Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells. Oncogene 1998, 16:2787-2796. 10.1038/sj.onc.1201802, 9652746.
    • (1998) Oncogene , vol.16 , pp. 2787-2796
    • Carter, S.1    Auer, K.L.2    Reardon, D.B.3    Birrer, M.4    Fisher, P.B.5    Valerie, K.6    Scmidtt-Ullrich, R.7    Mikkelsen, R.8    Dent, P.9
  • 24
    • 0032815618 scopus 로고    scopus 로고
    • Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
    • 25480, 10436007
    • Dent P, Reardon DB, Park JS, Bowers G, Logsdon C, Valerie K, Schmidt-Ullrich R. Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Mol Biol Cell 1999, 10:2493-2506. 25480, 10436007.
    • (1999) Mol Biol Cell , vol.10 , pp. 2493-2506
    • Dent, P.1    Reardon, D.B.2    Park, J.S.3    Bowers, G.4    Logsdon, C.5    Valerie, K.6    Schmidt-Ullrich, R.7
  • 25
    • 79960965892 scopus 로고    scopus 로고
    • Laser Capture microdissection and transcriptional profiling in archival FFPE tissue in prostate cancer
    • Joseph A, Gnanapragasam VJ. Laser Capture microdissection and transcriptional profiling in archival FFPE tissue in prostate cancer. Meth Mol Biol 2011, 755:291-300.
    • (2011) Meth Mol Biol , vol.755 , pp. 291-300
    • Joseph, A.1    Gnanapragasam, V.J.2
  • 27
    • 11244283209 scopus 로고    scopus 로고
    • The role of fibroblast growth factors and their receptors in prostate cancer
    • 10.1677/erc.1.00535, 15613447
    • Kwabi-Addo B, Ozen M, Ittmann M. The role of fibroblast growth factors and their receptors in prostate cancer. Endocr Relat Cancer 2004, 11:709-724. 10.1677/erc.1.00535, 15613447.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 709-724
    • Kwabi-Addo, B.1    Ozen, M.2    Ittmann, M.3
  • 28
    • 0034983287 scopus 로고    scopus 로고
    • Increased expression of FGF-8 isoforms and FGF receptors in human pre malignant prostatic intraepithelial neoplasia lesions and prostate cancer
    • Valve EM, Nevalainen MT, Nurmi MJ, Laato MK, Martikainen PM, Härkönen PL. Increased expression of FGF-8 isoforms and FGF receptors in human pre malignant prostatic intraepithelial neoplasia lesions and prostate cancer. Lab Invest 2001, 81:815-826.
    • (2001) Lab Invest , vol.81 , pp. 815-826
    • Valve, E.M.1    Nevalainen, M.T.2    Nurmi, M.J.3    Laato, M.K.4    Martikainen, P.M.5    Härkönen, P.L.6
  • 29
    • 9744241715 scopus 로고    scopus 로고
    • Fibroblast growth factor 17 is over-expressed in human prostate cancer
    • 10.1002/path.1668, 15538740
    • Heer R, Douglas D, Mathers ME, Robson CN, Leung HY. Fibroblast growth factor 17 is over-expressed in human prostate cancer. J Pathol 2004, 204:578-586. 10.1002/path.1668, 15538740.
    • (2004) J Pathol , vol.204 , pp. 578-586
    • Heer, R.1    Douglas, D.2    Mathers, M.E.3    Robson, C.N.4    Leung, H.Y.5
  • 31
    • 0033614366 scopus 로고    scopus 로고
    • FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease
    • 10.1038/sj.onc.1202624, 10348350
    • Dorkin TJ, Robinson MC, Marsh C, Bjartell A, Neal DE, Leung HY. FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease. Oncogene 1999, 18:2755-2761. 10.1038/sj.onc.1202624, 10348350.
    • (1999) Oncogene , vol.18 , pp. 2755-2761
    • Dorkin, T.J.1    Robinson, M.C.2    Marsh, C.3    Bjartell, A.4    Neal, D.E.5    Leung, H.Y.6
  • 32
    • 0036680093 scopus 로고    scopus 로고
    • Down-regulation of (IIIb) and (IIIc) isoforms of fibroblast growth factor receptor 2 (FGFR2) is associated with malignant progression in human prostate
    • 10.1002/pros.10104, 12111699
    • Naimi B, Latil A, Fournier G, Mangin P, Cussenot O, Berthon P. Down-regulation of (IIIb) and (IIIc) isoforms of fibroblast growth factor receptor 2 (FGFR2) is associated with malignant progression in human prostate. Prostate 2002, 52:245-252. 10.1002/pros.10104, 12111699.
    • (2002) Prostate , vol.52 , pp. 245-252
    • Naimi, B.1    Latil, A.2    Fournier, G.3    Mangin, P.4    Cussenot, O.5    Berthon, P.6
  • 33
    • 0033011048 scopus 로고    scopus 로고
    • FGF7/KGF triggers cell transformation and invasion on immortalised human prostatic epithelial PNT1A cells
    • 10.1002/(SICI)1097-0215(19990719)82:2<237::AID-IJC14>3.0.CO;2-Q, 10389758
    • Ropiquet F, Huguenin S, Villette JM, Ronflé V, Le Brun G, Maitland NJ, Cussenot O, Fiet J, Berthon P. FGF7/KGF triggers cell transformation and invasion on immortalised human prostatic epithelial PNT1A cells. Int J Cancer 1999, 82:237-243. 10.1002/(SICI)1097-0215(19990719)82:2<237::AID-IJC14>3.0.CO;2-Q, 10389758.
    • (1999) Int J Cancer , vol.82 , pp. 237-243
    • Ropiquet, F.1    Huguenin, S.2    Villette, J.M.3    Ronflé, V.4    Le Brun, G.5    Maitland, N.J.6    Cussenot, O.7    Fiet, J.8    Berthon, P.9
  • 34
    • 0036244318 scopus 로고    scopus 로고
    • Cell- and receptor isotype-specific phosphorylation of SNT1 by fibroblast growth factor receptor tyrosine kinases
    • 10.1290/1071-2690(2002)038<0178:CARISP>2.0.CO;2, 12026167
    • Wang F. Cell- and receptor isotype-specific phosphorylation of SNT1 by fibroblast growth factor receptor tyrosine kinases. In Vitro Cell Dev Biol Anim 2002, 38:178-183. 10.1290/1071-2690(2002)038<0178:CARISP>2.0.CO;2, 12026167.
    • (2002) In Vitro Cell Dev Biol Anim , vol.38 , pp. 178-183
    • Wang, F.1
  • 35
    • 0035814437 scopus 로고    scopus 로고
    • Role of fibroblast growth factor receptor signalling in prostate cancer cell survival
    • 10.1093/jnci/93.23.1783, 11734594
    • Ozen M, Giri D, Ropiquet F, Mansukhani A, Ittmann M. Role of fibroblast growth factor receptor signalling in prostate cancer cell survival. J Natl Cancer Inst 2001, 93:1783-1790. 10.1093/jnci/93.23.1783, 11734594.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1783-1790
    • Ozen, M.1    Giri, D.2    Ropiquet, F.3    Mansukhani, A.4    Ittmann, M.5
  • 36
    • 0034769605 scopus 로고    scopus 로고
    • MAPK dependence of DNA damage repair: ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashion
    • 10.1080/09553000110069317, 11682011
    • Yacoub A, Park JS, Qiao L, Dent P, Hagan MP. MAPK dependence of DNA damage repair: ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashion. Int J Radiat Biol 2001, 77:1067-1078. 10.1080/09553000110069317, 11682011.
    • (2001) Int J Radiat Biol , vol.77 , pp. 1067-1078
    • Yacoub, A.1    Park, J.S.2    Qiao, L.3    Dent, P.4    Hagan, M.P.5
  • 37
    • 0037382902 scopus 로고    scopus 로고
    • Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signalling
    • 10.1667/0033-7587(2003)159[0439:EGFAIR]2.0.CO;2, 12643788
    • Yacoub A, McKinstry R, Hinman D, Chung T, Dent P, Hagan MP. Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signalling. Radiat Res 2003, 159:439-452. 10.1667/0033-7587(2003)159[0439:EGFAIR]2.0.CO;2, 12643788.
    • (2003) Radiat Res , vol.159 , pp. 439-452
    • Yacoub, A.1    McKinstry, R.2    Hinman, D.3    Chung, T.4    Dent, P.5    Hagan, M.P.6
  • 38
    • 0033584391 scopus 로고    scopus 로고
    • Dominant negative EGFR-CD533 and inhibition of MAPK activity modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells
    • 10.1038/sj.onc.1202849, 10467423
    • Reardon DB, Contessa JN, Mikkelsen RB, Valerie K, Amir C, Dent P, Schmidt-Ullrich RK. Dominant negative EGFR-CD533 and inhibition of MAPK activity modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells. Oncogene 1999, 18:4756-4766. 10.1038/sj.onc.1202849, 10467423.
    • (1999) Oncogene , vol.18 , pp. 4756-4766
    • Reardon, D.B.1    Contessa, J.N.2    Mikkelsen, R.B.3    Valerie, K.4    Amir, C.5    Dent, P.6    Schmidt-Ullrich, R.K.7
  • 39
    • 3242686392 scopus 로고    scopus 로고
    • Sensitization of breast cancer cells to radiation by trastuzumab
    • Liang K, Lu Y, Jin W, Ang KK, Milas L, Fan Z. Sensitization of breast cancer cells to radiation by trastuzumab. Mol Cancer Ther 2003, 2:1113-1120.
    • (2003) Mol Cancer Ther , vol.2 , pp. 1113-1120
    • Liang, K.1    Lu, Y.2    Jin, W.3    Ang, K.K.4    Milas, L.5    Fan, Z.6
  • 40
    • 34247885803 scopus 로고    scopus 로고
    • Enhancement of radiation sensitivity, delay of proliferative recovery after radiation and abrogation of MAPK (p44/42) signalling by imatinib in glioblastoma cells
    • Quick QA, Gewirtz DA. Enhancement of radiation sensitivity, delay of proliferative recovery after radiation and abrogation of MAPK (p44/42) signalling by imatinib in glioblastoma cells. Int J Oncol 2006, 29:407-412.
    • (2006) Int J Oncol , vol.29 , pp. 407-412
    • Quick, Q.A.1    Gewirtz, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.