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Volumn 118, Issue 19, 2011, Pages 5163-5173

Wnt4 regulates thymic cellularity through the expansion of thymic epithelial cells and early thymic progenitors

Author keywords

[No Author keywords available]

Indexed keywords

WNT4 PROTEIN;

EID: 81055126764     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-04-350553     Document Type: Article
Times cited : (44)

References (50)
  • 1
    • 57349119343 scopus 로고    scopus 로고
    • Development and functional properties of thymic and extrathymic T lymphocytes
    • Heinonen KM, Perreault C. Development and functional properties of thymic and extrathymic T lymphocytes. Crit Rev Immunol. 2008;28(5):441-466.
    • (2008) Crit Rev Immunol , vol.28 , Issue.5 , pp. 441-466
    • Heinonen, K.M.1    Perreault, C.2
  • 2
    • 77955661045 scopus 로고    scopus 로고
    • Thymic fatness and approaches to enhance thymopoietic fitness in aging
    • Dixit VD. Thymic fatness and approaches to enhance thymopoietic fitness in aging. Curr Opin Immunol. 2010;22(4):521-528.
    • (2010) Curr Opin Immunol , vol.22 , Issue.4 , pp. 521-528
    • Dixit, V.D.1
  • 3
    • 0028812436 scopus 로고
    • Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy
    • Mackall CL, Fleisher TA, Brown MR, et al. Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy. N Engl J Med. 1995;332(3):143-149.
    • (1995) N Engl J Med , vol.332 , Issue.3 , pp. 143-149
    • Mackall, C.L.1    Fleisher, T.A.2    Brown, M.R.3
  • 4
    • 14944351958 scopus 로고    scopus 로고
    • Stress-induced immune dysfunction: Implications for health
    • DOI 10.1038/nri1571
    • Glaser R, Kiecolt-Glaser JK. Stress-induced immune dysfunction: implications for health. Nat Rev Immunol. 2005;5(3):243-251. (Pubitemid 40364825)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.3 , pp. 243-251
    • Glaser, R.1    Kiecolt-Glaser, J.K.2
  • 5
    • 79751512463 scopus 로고    scopus 로고
    • The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
    • Vandanmagsar B, Youm YH, Ravussin A, et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med. 2011;17(2):179-188.
    • (2011) Nat Med , vol.17 , Issue.2 , pp. 179-188
    • Vandanmagsar, B.1    Youm, Y.H.2    Ravussin, A.3
  • 6
    • 18144394761 scopus 로고    scopus 로고
    • Immune reconstitution following hematopoietic progenitor cell transplantation: Challenges for the future
    • DOI 10.1038/sj.bmt.1704848
    • Fry TJ, Mackall CL. Immune reconstitution following hematopoietic progenitor cell transplantation: challenges for the future. Bone Marrow Transplant. 2005;35 Suppl 1:S53-S57. (Pubitemid 40613924)
    • (2005) Bone Marrow Transplantation , vol.35 , Issue.SUPPL. 1
    • Fry, T.J.1    Mackall, C.L.2
  • 8
    • 79959529827 scopus 로고    scopus 로고
    • Thymic T-cell development in allogeneic stem cell transplantation
    • Krenger W, Blazar BR, Hollander GA. Thymic T-cell development in allogeneic stem cell transplantation. Blood. 2011;117(25):6768-6776.
    • (2011) Blood , vol.117 , Issue.25 , pp. 6768-6776
    • Krenger, W.1    Blazar, B.R.2    Hollander, G.A.3
  • 9
    • 34247882592 scopus 로고    scopus 로고
    • Zoned out: functional mapping of stromal signaling microenvironments in the thymus
    • DOI 10.1146/annurev.immunol.23.021704.115715
    • Petrie HT, Zuniga-Pflucker JC. Zoned out: functional mapping of stromal signaling microenvironments in the thymus. Annu Rev Immunol. 2007;25:649-679. (Pubitemid 46697920)
    • (2007) Annual Review of Immunology , vol.25 , pp. 649-679
    • Petrie, H.T.1    Zuniga-Pflucker, J.C.2
  • 10
    • 33645047906 scopus 로고    scopus 로고
    • Establishment and functioning of intrathymic microenvironments
    • Anderson G, Jenkinson WE, Jones T, et al. Establishment and functioning of intrathymic microenvironments. Immunol Rev. 2006;209:10-27.
    • (2006) Immunol Rev , vol.209 , pp. 10-27
    • Anderson, G.1    Jenkinson, W.E.2    Jones, T.3
  • 13
    • 77949312399 scopus 로고    scopus 로고
    • Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy
    • Cheng L, Guo J, Sun L, et al. Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy. J Biol Chem. 2010;285(8):5836-5847.
    • (2010) J Biol Chem , vol.285 , Issue.8 , pp. 5836-5847
    • Cheng, L.1    Guo, J.2    Sun, L.3
  • 14
    • 77949378933 scopus 로고    scopus 로고
    • DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration
    • Osada M, Jardine L, Misir R, Andl T, Millar SE, Pezzano M. DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS One. 2010;5(2):e9062.
    • (2010) PLoS One , vol.5 , Issue.2
    • Osada, M.1    Jardine, L.2    Misir, R.3    Andl, T.4    Millar, S.E.5    Pezzano, M.6
  • 15
    • 77953449167 scopus 로고    scopus 로고
    • Cutting edge: A thymocyte-thymic epithelial cell cross-talk dynamically regulates intrathymic IL-7 expression in vivo
    • Alves NL, Huntington ND, Mention JJ, Richard-Le GO, Di Santo JP. Cutting edge: a thymocyte-thymic epithelial cell cross-talk dynamically regulates intrathymic IL-7 expression in vivo. J Immunol. 2010;184(11):5949-5953.
    • (2010) J Immunol , vol.184 , Issue.11 , pp. 5949-5953
    • Alves, N.L.1    Huntington, N.D.2    Mention, J.J.3    Richard-Le, G.O.4    Di Santo, J.P.5
  • 16
    • 70349235967 scopus 로고    scopus 로고
    • Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult
    • Roberts NA, Desanti GE, Withers DR, et al. Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult. Eur J Immunol. 2009;39(9):2395-2402.
    • (2009) Eur J Immunol , vol.39 , Issue.9 , pp. 2395-2402
    • Roberts, N.A.1    Desanti, G.E.2    Withers, D.R.3
  • 17
    • 48749101937 scopus 로고    scopus 로고
    • WNT signalling in the immune system: WNT is spreading its wings
    • Staal FJ, Luis TC, Tiemessen MM. WNT signalling in the immune system: WNT is spreading its wings. Nat Rev Immunol. 2008;8(8):581-593.
    • (2008) Nat Rev Immunol , vol.8 , Issue.8 , pp. 581-593
    • Staal, F.J.1    Luis, T.C.2    Tiemessen, M.M.3
  • 18
    • 77953959985 scopus 로고    scopus 로고
    • TCF1 and beta-catenin regulate T cell development and function
    • Yu Q, Sharma A, Sen JM. TCF1 and beta-catenin regulate T cell development and function. Immunol Res. 2010;47(1-3):45-55.
    • (2010) Immunol Res , vol.47 , Issue.1-3 , pp. 45-55
    • Yu, Q.1    Sharma, A.2    Sen, J.M.3
  • 20
    • 64849101655 scopus 로고    scopus 로고
    • Stabilized β-catenin in thymic epithelial cells blocks thymus development and function
    • Zuklys S, Gill J, Keller MP, et al. Stabilized β-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009;182(5):2997-3007.
    • (2009) J Immunol , vol.182 , Issue.5 , pp. 2997-3007
    • Zuklys, S.1    Gill, J.2    Keller, M.P.3
  • 21
    • 33749411672 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC) is required for normal development of skin and thymus
    • Kuraguchi M, Wang XP, Bronson RT, et al. Adenomatous polyposis coli (APC) is required for normal development of skin and thymus. PLoS Genet. 2006;2(9):e146.
    • (2006) PLoS Genet , vol.2 , Issue.9
    • Kuraguchi, M.1    Wang, X.P.2    Bronson, R.T.3
  • 23
    • 46749097841 scopus 로고    scopus 로고
    • The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through beta-catenin-independent signaling
    • Louis I, Heinonen KM, Chagraoui J, Vainio S, Sauvageau G, Perreault C. The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through beta-catenin-independent signaling. Immunity. 2008;29(1):57-67.
    • (2008) Immunity , vol.29 , Issue.1 , pp. 57-67
    • Louis, I.1    Heinonen, K.M.2    Chagraoui, J.3    Vainio, S.4    Sauvageau, G.5    Perreault, C.6
  • 24
    • 33749452454 scopus 로고    scopus 로고
    • Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect
    • DOI 10.1172/JCI28310
    • Bowie MB, McKnight KD, Kent DG, McCaffrey L, Hoodless PA, Eaves CJ. Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. J Clin Invest. 2006;116(10):2808-2816. (Pubitemid 44511644)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.10 , pp. 2808-2816
    • Bowie, M.B.1    McKnight, K.D.2    Kent, D.G.3    McCaffrey, L.4    Hoodless, P.A.5    Eaves, C.J.6
  • 25
    • 79955608017 scopus 로고    scopus 로고
    • Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway
    • Heinonen KM, Ruiz Vanegas J, Lew D, Krosl J, Perreault C. Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway. PLoS One. 2011;6(4):e19279.
    • (2011) PLoS One , vol.6 , Issue.4
    • Heinonen, K.M.1    Ruiz Vanegas, J.2    Lew, D.3    Krosl, J.4    Perreault, C.5
  • 26
    • 0028985161 scopus 로고
    • An HMG-box-containing T-cell factor required for thymocyte differentiation
    • Verbeek S, Izon D, Hofhuis F, et al. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature. 1995;374(6517):70-74.
    • (1995) Nature , vol.374 , Issue.6517 , pp. 70-74
    • Verbeek, S.1    Izon, D.2    Hofhuis, F.3
  • 27
    • 0028588919 scopus 로고
    • Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
    • Stark K, Vainio S, Vassileva G, McMahon AP. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 1994;372(6507):679-683.
    • (1994) Nature , vol.372 , Issue.6507 , pp. 679-683
    • Stark, K.1    Vainio, S.2    Vassileva, G.3    McMahon, A.P.4
  • 28
    • 73249147327 scopus 로고    scopus 로고
    • Generation of an allele to inactivate Wnt4 gene function conditionally in the mouse
    • Shan J, Jokela T, Peltoketo H, Vainio S. Generation of an allele to inactivate Wnt4 gene function conditionally in the mouse. Genesis. 2009;47(11):782-788.
    • (2009) Genesis , vol.47 , Issue.11 , pp. 782-788
    • Shan, J.1    Jokela, T.2    Peltoketo, H.3    Vainio, S.4
  • 29
    • 65549089187 scopus 로고    scopus 로고
    • Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25
    • Gossens K, Naus S, Corbel SY, et al. Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25. J Exp Med. 2009;206(4):75-96.
    • (2009) J Exp Med , vol.206 , Issue.4 , pp. 75-96
    • Gossens, K.1    Naus, S.2    Corbel, S.Y.3
  • 30
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
    • DOI 10.1016/S1074-7613(02)00474-0
    • Schmitt TM, Zuniga-Pflücker JC. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity. 2002;17(12):749-756. (Pubitemid 35477794)
    • (2002) Immunity , vol.17 , Issue.6 , pp. 749-756
    • Schmitt, T.M.1    Zuniga-Pflucker, J.C.2
  • 31
    • 33845239216 scopus 로고    scopus 로고
    • Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells
    • DOI 10.1182/blood-2006-02-004531
    • Gray DH, Seach N, Ueno T, et al. Developmental kinetics, turnover and stimulatory capacity of thymic epithelial cells. Blood. 2006;108(12):3777-3785. (Pubitemid 44864559)
    • (2006) Blood , vol.108 , Issue.12 , pp. 3777-3785
    • Gray, D.H.D.1    Seach, N.2    Ueno, T.3    Milton, M.K.4    Liston, A.5    Lew, A.M.6    Goodnow, C.C.7    Boyd, R.L.8
  • 32
    • 66149121915 scopus 로고    scopus 로고
    • A novel method for the generation of reaggregated organotypic cultures that permits juxtaposition of defined cell populations
    • Sheridan JM, Taoudi S, Medvinsky A, Blackburn CC. A novel method for the generation of reaggregated organotypic cultures that permits juxtaposition of defined cell populations. Genesis. 2009;47(5):346-351.
    • (2009) Genesis , vol.47 , Issue.5 , pp. 346-351
    • Sheridan, J.M.1    Taoudi, S.2    Medvinsky, A.3    Blackburn, C.C.4
  • 34
    • 0035134933 scopus 로고    scopus 로고
    • Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
    • Staal FJ, Meeldijk J, Moerer P, et al. Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription. Eur J Immunol. 2001;31(1):285-293.
    • (2001) Eur J Immunol , vol.31 , Issue.1 , pp. 285-293
    • Staal, F.J.1    Meeldijk, J.2    Moerer, P.3
  • 36
    • 78049421614 scopus 로고    scopus 로고
    • Notch dimerization is required for leukemogenesis and T-cell development
    • Liu H, Chi AW, Arnett KL, et al. Notch dimerization is required for leukemogenesis and T-cell development. Genes Dev. 2010;24(21):2395-2407.
    • (2010) Genes Dev , vol.24 , Issue.21 , pp. 2395-2407
    • Liu, H.1    Chi, A.W.2    Arnett, K.L.3
  • 37
    • 79551636784 scopus 로고    scopus 로고
    • Immature T-cell clustering and efficient differentiation require the polarity protein Scribble
    • Pike KA, Kulkarni S, Pawson T. Immature T-cell clustering and efficient differentiation require the polarity protein Scribble. Proc Natl Acad Sci U S A. 2011;108(3):1116-1121.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.3 , pp. 1116-1121
    • Pike, K.A.1    Kulkarni, S.2    Pawson, T.3
  • 38
    • 38049105637 scopus 로고    scopus 로고
    • Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin
    • Jeannet G, Scheller M, Scarpellino L, et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood. 2008;111(1):142-149.
    • (2008) Blood , vol.111 , Issue.1 , pp. 142-149
    • Jeannet, G.1    Scheller, M.2    Scarpellino, L.3
  • 39
    • 77953107073 scopus 로고    scopus 로고
    • Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory
    • Jeannet G, Boudousquie C, Gardiol N, Kang J, Huelsken J, Held W. Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory. Proc Natl Acad Sci U S A. 2010;107(21):9777-9782.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.21 , pp. 9777-9782
    • Jeannet, G.1    Boudousquie, C.2    Gardiol, N.3    Kang, J.4    Huelsken, J.5    Held, W.6
  • 40
    • 79961140554 scopus 로고    scopus 로고
    • A critical role for TCF-1 in T-lineage specification and differentiation
    • Weber BN, Chi AW, Chavez A, et al. A critical role for TCF-1 in T-lineage specification and differentiation. Nature. 2011;476(7358):63-68.
    • (2011) Nature , vol.476 , Issue.7358 , pp. 63-68
    • Weber, B.N.1    Chi, A.W.2    Chavez, A.3
  • 41
    • 77950407764 scopus 로고    scopus 로고
    • CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus
    • Zlotoff DA, Sambandam A, Logan TD, Bell JJ, Schwarz BA, Bhandoola A. CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus. Blood. 2010;115(10):1897-1905.
    • (2010) Blood , vol.115 , Issue.10 , pp. 1897-1905
    • Zlotoff, D.A.1    Sambandam, A.2    Logan, T.D.3    Bell, J.J.4    Schwarz, B.A.5    Bhandoola, A.6
  • 42
    • 3242747324 scopus 로고    scopus 로고
    • Regulation of thymus size by competition for stromal niches among early T cell progenitors
    • Prockop SE, Petrie HT. Regulation of thymus size by competition for stromal niches among early T cell progenitors. J Immunol. 2004;173(3):1604-1611. (Pubitemid 38971590)
    • (2004) Journal of Immunology , vol.173 , Issue.3 , pp. 1604-1611
    • Prockop, S.E.1    Petrie, H.T.2
  • 45
    • 77956287646 scopus 로고    scopus 로고
    • Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence
    • Kvell K, Varecza Z, Bartis D, et al. Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence. PLoS One. 2010;5(5):e10701.
    • (2010) PLoS One , vol.5 , Issue.5
    • Kvell, K.1    Varecza, Z.2    Bartis, D.3
  • 46
    • 0036305567 scopus 로고    scopus 로고
    • + thymic epithelial cells
    • DOI 10.1038/ni812
    • Gill J, Malin M, Hollander GA, Boyd R. Generation of a complete thymic microenvironment by MTS24+ thymic epithelial cells. Nat Immunol. 2002;3(7):635-642. (Pubitemid 34752472)
    • (2002) Nature Immunology , vol.3 , Issue.7 , pp. 635-642
    • Gill, J.1    Malin, M.2    Hollander, G.A.3    Boyd, R.4
  • 47
    • 33750126450 scopus 로고    scopus 로고
    • Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment
    • DOI 10.1038/ni1393, PII NI1393
    • McKenzie JL, Gan OI, Doedens M, Wang JC, Dick JE. Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment. Nat Immunol. 2006;7(11):1225-1233. (Pubitemid 44594319)
    • (2006) Nature Immunology , vol.7 , Issue.11 , pp. 1225-1233
    • McKenzie, J.L.1    Gan, O.I.2    Doedens, M.3    Wang, J.C.Y.4    Dick, J.E.5
  • 49
    • 0037105620 scopus 로고    scopus 로고
    • Cutting edge: Thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus
    • Klug DB, Carter C, Gimenez-Conti IB, Richie ER. Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus. J Immunol. 2002;169(6):2842-2845. (Pubitemid 35013123)
    • (2002) Journal of Immunology , vol.169 , Issue.6 , pp. 2842-2845
    • Klug, D.B.1    Carter, C.2    Gimenez-Conti, I.B.3    Richie, E.R.4
  • 50
    • 0014755972 scopus 로고
    • Histological observations on thymus grafts placed under the renal capsule in mice, with special reference to the occurrence of lymphoid nodules
    • Abe K, Ito T. Histological observations on thymus grafts placed under the renal capsule in mice, with special reference to the occurrence of lymphoid nodules. Arch Histol Jpn. 1970;31(3):321-332.
    • (1970) Arch Histol Jpn , vol.31 , Issue.3 , pp. 321-332
    • Abe, K.1    Ito, T.2


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