-
2
-
-
17444372347
-
Changes in thymic function with age and during the treatment of HIV infection
-
DOI 10.1038/25374
-
Douek, D. C., R. D. McFarland, P. H. Keiser, E. A. Gage, J. M. Massey, B. F. Haynes, M. A. Polis, A. T. Haase, M. B. Feinberg, J. L. Sullivan, et al. 1998. Changes in thymic function with age and during the treatment of HIV infection. Nature 396: 690-695. (Pubitemid 29003949)
-
(1998)
Nature
, vol.396
, Issue.6712
, pp. 690-695
-
-
Douek, D.C.1
McFarland, R.D.2
Keiser, P.H.3
Gage, E.A.4
Massey, J.M.5
Haynes, B.F.6
Polis, M.A.7
Haase, A.T.8
Feinberg, M.B.9
Sullivan, J.L.10
Jamieson, B.D.11
Zack, J.A.12
Picker, L.J.13
Koup, R.A.14
-
3
-
-
21044451726
-
The influence of age on T cell generation and TCR diversity
-
Naylor, K., G. Li, A. N. Vallejo, W. W. Lee, K. Koetz, E. Bryl, J. Witkowski, J. Fulbright, C. M. Weyand, and J. J. Goronzy. 2005. The influence of age on T cell generation and TCR diversity. J. Immunol. 174: 7446-7452. (Pubitemid 40705717)
-
(2005)
Journal of Immunology
, vol.174
, Issue.11
, pp. 7446-7452
-
-
Naylor, K.1
Li, G.2
Vallelo, A.N.3
Lee, W.-W.4
Koetz, K.5
Bryl, E.6
Witkowski, J.7
Fulbright, J.8
Weyand, C.M.9
Goronzy, J.J.10
-
4
-
-
0029943897
-
Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing
-
Mackall, C. L., C. V. Bare, L. A. Granger, S. O. Sharrow, J. A. Titus, and R. E. Gress. 1996. Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing. J. Immunol. 156: 4609-4616.
-
(1996)
J. Immunol.
, vol.156
, pp. 4609-4616
-
-
Mackall, C.L.1
Bare, C.V.2
Granger, L.A.3
Sharrow, S.O.4
Titus, J.A.5
Gress, R.E.6
-
5
-
-
41149170727
-
Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus
-
Yager, E. J., A. Ahmed, K. Lanzer, T. D. Randall, D. L. Woodland, and M. A. Blackman. 2008. Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J. Exp. Med. 205: 711-723.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 711-723
-
-
Yager, E.J.1
Ahmed, A.2
Lanzer, K.3
Randall, T.D.4
Woodland, D.L.5
Blackman, M.A.6
-
6
-
-
20144387499
-
Age-dependent incidence, time course, and consequences of thymic renewal in adults
-
Hakim, F. T., S. A. Memon, R. Cepeda, E. C. Jones, C. K. Chow, C. Kasten-Sportes, J. Odom, B. A. Vance, B. L. Christensen, C. L. Mackall, and R. E. Gress. 2005. Age-dependent incidence, time course, and consequences of thymic renewal in adults. J. Clin. Invest. 115: 930-939.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 930-939
-
-
Hakim, F.T.1
Memon, S.A.2
Cepeda, R.3
Jones, E.C.4
Chow, C.K.5
Kasten-Sportes, C.6
Odom, J.7
Vance, B.A.8
Christensen, B.L.9
Mackall, C.L.10
Gress, R.E.11
-
7
-
-
33845239216
-
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells
-
Gray, D. H., N. Seach, T. Ueno, M. K. Milton, A. Liston, A. M. Lew, C. C. Goodnow, and R. L. Boyd. 2006. Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. Blood 108: 3777-3785.
-
(2006)
Blood
, vol.108
, pp. 3777-3785
-
-
Gray, D.H.1
Seach, N.2
Ueno, T.3
Milton, M.K.4
Liston, A.5
Lew, A.M.6
Goodnow, C.C.7
Boyd, R.L.8
-
8
-
-
33846867492
-
PDGFRα-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches
-
Jenkinson, W. E., S. W. Rossi, S. M. Parnell, E. J. Jenkinson, and G. Anderson. 2007. PDGFRα-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches. Blood 109: 954-960.
-
(2007)
Blood
, vol.109
, pp. 954-960
-
-
Jenkinson, W.E.1
Rossi, S.W.2
Parnell, S.M.3
Jenkinson, E.J.4
Anderson, G.5
-
9
-
-
33947192136
-
Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging
-
DOI 10.1182/blood-2006-08-043794
-
Min, D., A. Panoskaltsis-Mortari, O. M. Kuro, G. A. Hollander, B. R. Blazar, and K. I. Weinberg. 2007. Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging. Blood 109: 2529-2537. (Pubitemid 46425898)
-
(2007)
Blood
, vol.109
, Issue.6
, pp. 2529-2537
-
-
Min, D.1
Panoskaltsis-Mortari, A.2
Kuro-o, M.3
Hollander, G.A.4
Blazar, B.R.5
Weinberg, K.I.6
-
10
-
-
36549062401
-
Impact of niche aging on thymic regeneration and immune reconstitution
-
DOI 10.1016/j.smim.2007.10.006, PII S1044532307000802, Giving T Cells a Chance to Come Back
-
Chidgey, A., J. Dudakov, N. Seach, and R. Boyd. 2007. Impact of niche aging on thymic regeneration and immune reconstitution. Semin. Immunol. 19: 331-340. (Pubitemid 350181532)
-
(2007)
Seminars in Immunology
, vol.19
, Issue.5
, pp. 331-340
-
-
Chidgey, A.1
Dudakov, J.2
Seach, N.3
Boyd, R.4
-
11
-
-
33745516115
-
Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium
-
Rossi, S. W., W. E. Jenkinson, G. Anderson, and E. J. Jenkinson. 2006. Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature 441: 988-991.
-
(2006)
Nature
, vol.441
, pp. 988-991
-
-
Rossi, S.W.1
Jenkinson, W.E.2
Anderson, G.3
Jenkinson, E.J.4
-
12
-
-
2442647655
-
Functional evidence for a single endodermal origin for the thymic epithelium
-
DOI 10.1038/ni1064
-
Gordon, J., V. A. Wilson, N. F. Blair, J. Sheridan, A. Farley, L. Wilson, N. R. Manley, and C. C. Blackburn. 2004. Functional evidence for a single endodermal origin for the thymic epithelium. Nat. Immunol. 5: 546-553. (Pubitemid 38660468)
-
(2004)
Nature Immunology
, vol.5
, Issue.5
, pp. 546-553
-
-
Gordon, J.1
Wilson, V.A.2
Blair, N.F.3
Sheridan, J.4
Farley, A.5
Wilson, L.6
Manley, N.R.7
Blackburn, C.C.8
-
13
-
-
33745532385
-
Formation of a functional thymus initiated by a postnatal epithelial progenitor cell
-
Bleul, C. C., T. Corbeaux, A. Reuter, P. Fisch, J. S. Monting, and T. Boehm. 2006. Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. Nature 441: 992-996.
-
(2006)
Nature
, vol.441
, pp. 992-996
-
-
Bleul, C.C.1
Corbeaux, T.2
Reuter, A.3
Fisch, P.4
Monting, J.S.5
Boehm, T.6
-
14
-
-
0029920145
-
Two genetically separable steps in the differentiation of thymic epithelium
-
Nehls, M., B. Kyewski, M. Messerle, R. Waldschutz, K. Schuddekopf, A. J. Smith, and T. Boehm. 1996. Two genetically separable steps in the differentiation of thymic epithelium. Science 272: 886-889. (Pubitemid 26154594)
-
(1996)
Science
, vol.272
, Issue.5263
, pp. 886-889
-
-
Nehls, M.1
Kyewski, B.2
Messerle, M.3
Waldschutz, R.4
Schuddekopf, K.5
Smith, A.J.H.6
Boehm, T.7
-
15
-
-
28444475518
-
Development of functional thymic epithelial cells occurs independently of lymphostromal interactions
-
Jenkinson, W. E., S. W. Rossi, E. J. Jenkinson, and G. Anderson. 2005. Development of functional thymic epithelial cells occurs independently of lymphostromal interactions. Mech. Dev. 122: 1294-1299.
-
(2005)
Mech. Dev.
, vol.122
, pp. 1294-1299
-
-
Jenkinson, W.E.1
Rossi, S.W.2
Jenkinson, E.J.3
Anderson, G.4
-
16
-
-
0242624627
-
A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation
-
Su, D. M., S. Navarre, W. J. Oh, B. G. Condie, and N. R. Manley. 2003. A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation. Nat. Immunol. 4: 1128-1135.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1128-1135
-
-
Su, D.M.1
Navarre, S.2
Oh, W.J.3
Condie, B.G.4
Manley, N.R.5
-
17
-
-
0035496231
-
Lymphostromal interactions in thymic development and function
-
Anderson, G., and E. J. Jenkinson. 2001. Lymphostromal interactions in thymic development and function. Nat. Rev. Immunol. 1: 31-40. (Pubitemid 33741973)
-
(2001)
Nature Reviews Immunology
, vol.1
, Issue.1
, pp. 31-40
-
-
Anderson, G.1
Jenkinson, E.J.2
-
18
-
-
34548798748
-
Redefining epithelial progenitor potential in the developing thymus
-
DOI 10.1002/eji.200737275
-
Rossi, S. W., A. P. Chidgey, S. M. Parnell, W. E. Jenkinson, H. S. Scott, R. L. Boyd, E. J. Jenkinson, and G. Anderson. 2007. Redefining epithelial progenitor potential in the developing thymus. Eur. J. Immunol. 37: 2411-2418. (Pubitemid 47423612)
-
(2007)
European Journal of Immunology
, vol.37
, Issue.9
, pp. 2411-2418
-
-
Rossi, S.W.1
Chidgey, A.P.2
Parnell, S.M.3
Jenkinson, W.E.4
Scott, H.S.5
Boyd, R.L.6
Jenkinson, E.J.7
Anderson, G.8
-
19
-
-
33847210675
-
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver
-
Stanger, B. Z., A. J. Tanaka, and D. A. Melton. 2007. Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver. Nature 445: 886-891.
-
(2007)
Nature
, vol.445
, pp. 886-891
-
-
Stanger, B.Z.1
Tanaka, A.J.2
Melton, D.A.3
-
20
-
-
0029999218
-
The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors
-
Blackburn, C. C., C. L. Augustine, R. Li, R. P. Harvey, M. A. Malin, R. L. Boyd, J. F. Miller, and G. Morahan. 1996. The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors. Proc. Natl. Acad. Sci. USA 93: 5742-5746.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5742-5746
-
-
Blackburn, C.C.1
Augustine, C.L.2
Li, R.3
Harvey, R.P.4
Malin, M.A.5
Boyd, R.L.6
Miller, J.F.7
Morahan, G.8
-
21
-
-
0042662851
-
Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors
-
Jenkinson, W. E., E. J. Jenkinson, and G. Anderson. 2003. Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors. J. Exp. Med. 198: 325-332.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 325-332
-
-
Jenkinson, W.E.1
Jenkinson, E.J.2
Anderson, G.3
-
22
-
-
0036470005
-
Analysis of thymic stromal cell populations using flow cytometry
-
DOI 10.1016/S0022-1759(01)00493-8, PII S0022175901004938
-
Gray, D. H., A. P. Chidgey, and R. L. Boyd. 2002. Analysis of thymic stromal cell populations using flow cytometry. J. Immunol. Methods 260: 15-28. (Pubitemid 34132869)
-
(2002)
Journal of Immunological Methods
, vol.260
, Issue.1-2
, pp. 15-28
-
-
Gray, D.H.D.1
Chidgey, A.P.2
Boyd, R.L.3
-
23
-
-
36248948548
-
The role of lymphoid tissue inducer cells in splenic white pulp development
-
Withers, D. R., M. Y. Kim, V. Bekiaris, S. W. Rossi, W. E. Jenkinson, F. Gaspal, F. McConnell, J. H. Caamano, G. Anderson, and P. J. Lane. 2007. The role of lymphoid tissue inducer cells in splenic white pulp development. Eur. J. Immunol. 37: 3240-3245.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 3240-3245
-
-
Withers, D.R.1
Kim, M.Y.2
Bekiaris, V.3
Rossi, S.W.4
Jenkinson, W.E.5
Gaspal, F.6
McConnell, F.7
Caamano, J.H.8
Anderson, G.9
Lane, P.J.10
-
24
-
-
23044513881
-
Gene targeting of VEGF-A in thymus epithelium disrupts thymus blood vessel architecture
-
Muller, S. M., G. Terszowski, C. Blum, C. Haller, V. Anquez, S. Kuschert, P. Carmeliet, H. G. Augustin, and H. R. Rodewald. 2005. Gene targeting of VEGF-A in thymus epithelium disrupts thymus blood vessel architecture. Proc. Natl. Acad. Sci. USA 102: 10587-10592.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 10587-10592
-
-
Muller, S.M.1
Terszowski, G.2
Blum, C.3
Haller, C.4
Anquez, V.5
Kuschert, S.6
Carmeliet, P.7
Augustin, H.G.8
Rodewald, H.R.9
-
26
-
-
0033753252
-
Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation
-
Manley, N. R. 2000. Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation. Semin. Immunol. 12: 421-428.
-
(2000)
Semin. Immunol.
, vol.12
, pp. 421-428
-
-
Manley, N.R.1
-
27
-
-
0021845550
-
Stromal cell types in the developing thymus of the normal and nude mouse embryo
-
DOI 10.1002/eji.1830150707
-
Van Vliet, E., E. J. Jenkinson, R. Kingston, J. J. Owen, and W. Van Ewijk. 1985. Stromal cell types in the developing thymus of the normal and nude mouse embryo. Eur. J. Immunol. 15: 675-681. (Pubitemid 15028939)
-
(1985)
European Journal of Immunology
, vol.15
, Issue.7
, pp. 675-681
-
-
Van Vliet, E.1
Jenkinson, E.J.2
Kingston, R.3
-
28
-
-
0019464261
-
Major histocompatibility complex antigen expression on the epithelium of the developing thymus in normal and nude mice
-
Jenkinson, E. J., W. Van Ewijk, and J. J. Owen. 1981. Major histocompatibility complex antigen expression on the epithelium of the developing thymus in normal and nude mice. J. Exp. Med. 153: 280-292.
-
(1981)
J. Exp. Med.
, vol.153
, pp. 280-292
-
-
Jenkinson, E.J.1
Van Ewijk, W.2
Owen, J.J.3
-
29
-
-
3242747324
-
Regulation of thymus size by competition for stromal niches among early T cell progenitors
-
Prockop, S. E., and H. T. Petrie. 2004. Regulation of thymus size by competition for stromal niches among early T cell progenitors. J. Immunol. 173: 1604-1611.
-
(2004)
J. Immunol.
, vol.173
, pp. 1604-1611
-
-
Prockop, S.E.1
Petrie, H.T.2
-
30
-
-
0035881543
-
Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb
-
Revest, J. M., R. K. Suniara, K. Kerr, J. J. Owen, and C. Dickson. 2001. Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb. J. Immunol. 167: 1954-1961.
-
(2001)
J. Immunol.
, vol.167
, pp. 1954-1961
-
-
Revest, J.M.1
Suniara, R.K.2
Kerr, K.3
Owen, J.J.4
Dickson, C.5
-
31
-
-
33750608542
-
Coordination between CCR7- And CCR9-mediated chemokine signals in prevascular fetal thymus colonization
-
DOI 10.1182/blood-2006-05-024190
-
Liu, C., F. Saito, Z. Liu, Y. Lei, S. Uehara, P. Love, M. Lipp, S. Kondo, N. Manley, and Y. Takahama. 2006. Coordination between CCR7- and CCR9- mediated chemokine signals in prevascular fetal thymus colonization. Blood 108: 2531-2539. (Pubitemid 44776985)
-
(2006)
Blood
, vol.108
, Issue.8
, pp. 2531-2539
-
-
Liu, C.1
Saito, F.2
Liu, Z.3
Lei, Y.4
Uehara, S.5
Love, P.6
Lipp, M.7
Kondo, S.8
Manley, N.9
Takahama, Y.10
-
32
-
-
23444461765
-
Activation of thymic regeneration in mice and humans following androgen blockade
-
Sutherland, J. S., G. L. Goldberg, M. V. Hammett, A. P. Uldrich, S. P. Berzins, T. S. Heng, B. R. Blazar, J. L. Millar, M. A. Malin, A. P. Chidgey, and R. L. Boyd. 2005. Activation of thymic regeneration in mice and humans following androgen blockade. J. Immunol. 175: 2741-2753.
-
(2005)
J. Immunol.
, vol.175
, pp. 2741-2753
-
-
Sutherland, J.S.1
Goldberg, G.L.2
Hammett, M.V.3
Uldrich, A.P.4
Berzins, S.P.5
Heng, T.S.6
Blazar, B.R.7
Millar, J.L.8
Malin, M.A.9
Chidgey, A.P.10
Boyd, R.L.11
-
33
-
-
34548760932
-
Back to the beginning: The quest for thymic epithelial stem cells
-
Swann, J. B., and T. Boehm. 2007. Back to the beginning: the quest for thymic epithelial stem cells. Eur. J. Immunol. 37: 2364-2366.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 2364-2366
-
-
Swann, J.B.1
Boehm, T.2
-
34
-
-
36549062871
-
Human T cell reconstitution in DiGeorge syndrome and HIV-1 infection
-
DOI 10.1016/j.smim.2007.10.002, PII S1044532307000760, Giving T Cells a Chance to Come Back
-
Hudson, L. L., M. Louise Markert, B. H. Devlin, B. F. Haynes, and G. D. Sempowski. 2007. Human T cell reconstitution in DiGeorge syndrome and HIV-1 infection. Semin. Immunol. 19: 297-309. (Pubitemid 350181528)
-
(2007)
Seminars in Immunology
, vol.19
, Issue.5
, pp. 297-309
-
-
Hudson, L.L.1
Louise Markert, M.2
Devlin, B.H.3
Haynes, B.F.4
Sempowski, G.D.5
-
35
-
-
34248381768
-
Review of 54 patients with complete DiGeorge anomaly enrolled in protocols for thymus transplantation: Outcome of 44 consecutive transplants
-
Markert, M. L., B. H. Devlin, M. J. Alexieff, J. Li, E. A. McCarthy, S. E. Gupton, I. K. Chinn, L. P. Hale, T. B. Kepler, M. He, et al. 2007. Review of 54 patients with complete DiGeorge anomaly enrolled in protocols for thymus transplantation: outcome of 44 consecutive transplants. Blood 109: 4539-4547.
-
(2007)
Blood
, vol.109
, pp. 4539-4547
-
-
Markert, M.L.1
Devlin, B.H.2
Alexieff, M.J.3
Li, J.4
McCarthy, E.A.5
Gupton, S.E.6
Chinn, I.K.7
Hale, L.P.8
Kepler, T.B.9
He, M.10
|