메뉴 건너뛰기




Volumn 6, Issue 4, 2011, Pages

Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLOHEXIMIDE; FRIZZLED PROTEIN; FRIZZLED PROTEIN 6; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE P38; RAC1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; WNT4 PROTEIN; CALCIUM; FZD6 PROTEIN, MOUSE; G PROTEIN COUPLED RECEPTOR; WNT PROTEIN;

EID: 79955608017     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019279     Document Type: Article
Times cited : (51)

References (54)
  • 1
    • 70349932747 scopus 로고    scopus 로고
    • Towards an integrated view of Wnt signaling in development
    • van Amerongen R, Nusse R, (2009) Towards an integrated view of Wnt signaling in development. Development 136: 3205-3214.
    • (2009) Development , vol.136 , pp. 3205-3214
    • van Amerongen, R.1    Nusse, R.2
  • 2
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S, Moon RT, (2009) Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 10: 468-477.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 3
    • 77952954695 scopus 로고    scopus 로고
    • When pathways collide: collaboration and connivance among signalling proteins in development
    • McNeill H, Woodgett JR, (2010) When pathways collide: collaboration and connivance among signalling proteins in development. Nat Rev Mol Cell Biol 11: 404-413.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 404-413
    • McNeill, H.1    Woodgett, J.R.2
  • 4
    • 37349025355 scopus 로고    scopus 로고
    • SnapShot: Noncanonical Wnt signaling pathways
    • Semenov MV, Habas R, Macdonald BT, He X, (2007) SnapShot: Noncanonical Wnt signaling pathways. Cell 131: 1378.
    • (2007) Cell , vol.131 , pp. 1378
    • Semenov, M.V.1    Habas, R.2    Macdonald, B.T.3    He, X.4
  • 5
    • 66049092616 scopus 로고    scopus 로고
    • Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells
    • Le Grand F, Jones AE, Seale V, Scime A, Rudnicki MA, (2009) Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. Cell Stem Cell 4: 535-547.
    • (2009) Cell Stem Cell , vol.4 , pp. 535-547
    • Le Grand, F.1    Jones, A.E.2    Seale, V.3    Scime, A.4    Rudnicki, M.A.5
  • 6
    • 60849103074 scopus 로고    scopus 로고
    • Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells
    • Vijayaragavan K, Szabo E, Bosse M, Ramos-Mejia V, Moon RT, et al. (2009) Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells. Cell Stem Cell 4: 248-262.
    • (2009) Cell Stem Cell , vol.4 , pp. 248-262
    • Vijayaragavan, K.1    Szabo, E.2    Bosse, M.3    Ramos-Mejia, V.4    Moon, R.T.5
  • 7
    • 11244305618 scopus 로고    scopus 로고
    • Wnt signalling and haematopoiesis: a Wnt-Wnt situation
    • Staal FJT, Clevers HC, (2005) Wnt signalling and haematopoiesis: a Wnt-Wnt situation. Nat Rev Immunol 5: 21-30.
    • (2005) Nat Rev Immunol , vol.5 , pp. 21-30
    • Staal, F.J.T.1    Clevers, H.C.2
  • 8
    • 48749101937 scopus 로고    scopus 로고
    • WNT signalling in the immune system: WNT is spreading its wings
    • Staal FJ, Luis TC, Tiemessen MM, (2008) WNT signalling in the immune system: WNT is spreading its wings. Nat Rev Immunol 8: 581-593.
    • (2008) Nat Rev Immunol , vol.8 , pp. 581-593
    • Staal, F.J.1    Luis, T.C.2    Tiemessen, M.M.3
  • 9
    • 36649002031 scopus 로고    scopus 로고
    • Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo
    • Zhao C, Blum J, Chen A, Kwon HY, Jung SH, et al. (2007) Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell 12: 528-541.
    • (2007) Cancer Cell , vol.12 , pp. 528-541
    • Zhao, C.1    Blum, J.2    Chen, A.3    Kwon, H.Y.4    Jung, S.H.5
  • 10
    • 60249101799 scopus 로고    scopus 로고
    • Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation
    • Luis TC, Weerkamp F, Naber BA, Baert MR, de Haas EF, et al. (2009) Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation. Blood 113: 546-554.
    • (2009) Blood , vol.113 , pp. 546-554
    • Luis, T.C.1    Weerkamp, F.2    Naber, B.A.3    Baert, M.R.4    de Haas, E.F.5
  • 11
    • 39749178390 scopus 로고    scopus 로고
    • Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo
    • Fleming HE, Janzen V, Lo Celso C, Guo M, Leahy KM, et al. (2008) Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell 2: 274-283.
    • (2008) Cell Stem Cell , vol.2 , pp. 274-283
    • Fleming, H.E.1    Janzen, V.2    Lo Celso, C.3    Guo, M.4    Leahy, K.M.5
  • 12
    • 77949424030 scopus 로고    scopus 로고
    • Non-canonical Wnt signaling pathways in hematopoiesis
    • Kokolus K, Nemeth MJ, (2010) Non-canonical Wnt signaling pathways in hematopoiesis. Immunol Res 46: 155-164.
    • (2010) Immunol Res , vol.46 , pp. 155-164
    • Kokolus, K.1    Nemeth, M.J.2
  • 13
    • 0037452998 scopus 로고    scopus 로고
    • Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo
    • Murdoch B, Chadwick K, Martin M, Shojaei F, Shah KV, et al. (2003) Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. Proc Natl Acad Sci U S A 100: 3422-3427.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 3422-3427
    • Murdoch, B.1    Chadwick, K.2    Martin, M.3    Shojaei, F.4    Shah, K.V.5
  • 14
    • 34848922753 scopus 로고    scopus 로고
    • Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation
    • Nemeth MJ, Topol L, Anderson SM, Yang Y, Bodine DM, (2007) Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation. Proc Natl Acad Sci U S A 104: 15436-15441.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15436-15441
    • Nemeth, M.J.1    Topol, L.2    Anderson, S.M.3    Yang, Y.4    Bodine, D.M.5
  • 16
    • 46749097841 scopus 로고    scopus 로고
    • The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through β-catenin-independent signaling
    • Louis J, Heinonen K, Chagraoui J, Vainio S, Sauvageau G, et al. (2008) The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through β-catenin-independent signaling. Immunity 29: 57-67.
    • (2008) Immunity , vol.29 , pp. 57-67
    • Louis, J.1    Heinonen, K.2    Chagraoui, J.3    Vainio, S.4    Sauvageau, G.5
  • 17
    • 20244387299 scopus 로고    scopus 로고
    • Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
    • Adolfsson J, Mansson R, Buza-Vidas N, Hultquist A, Liuba K, et al. (2005) Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121: 295-306.
    • (2005) Cell , vol.121 , pp. 295-306
    • Adolfsson, J.1    Mansson, R.2    Buza-Vidas, N.3    Hultquist, A.4    Liuba, K.5
  • 18
    • 35548939080 scopus 로고    scopus 로고
    • Critical role of FLT3 ligand in IL-7 receptor-independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors
    • Sitnicka E, Buza-Vidas N, Ahlenius H, Cilio CM, Gekas C, et al. (2007) Critical role of FLT3 ligand in IL-7 receptor-independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors. Blood 110: 2955-2964.
    • (2007) Blood , vol.110 , pp. 2955-2964
    • Sitnicka, E.1    Buza-Vidas, N.2    Ahlenius, H.3    Cilio, C.M.4    Gekas, C.5
  • 19
    • 34250212481 scopus 로고    scopus 로고
    • Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from
    • Bhandoola A, von Boehmer H, Petrie HT, Zuniga-Pflucker JC, (2007) Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from. Immunity 26: 678-689.
    • (2007) Immunity , vol.26 , pp. 678-689
    • Bhandoola, A.1    von Boehmer, H.2    Petrie, H.T.3    Zuniga-Pflucker, J.C.4
  • 20
    • 24644499046 scopus 로고    scopus 로고
    • Wnt and calcium signaling: β-Catenin-independent pathways
    • Kohn AD, Moon RT, (2005) Wnt and calcium signaling: β-Catenin-independent pathways. Cell Calcium 38: 439-446.
    • (2005) Cell Calcium , vol.38 , pp. 439-446
    • Kohn, A.D.1    Moon, R.T.2
  • 21
    • 40649127731 scopus 로고    scopus 로고
    • Wnt4 inhibits β-catenin/TCF signaling by redirecting β-catenin to the cell membrane
    • Bernard P, Fleming A, Lacombe A, Harley VR, Vilain E, (2007) Wnt4 inhibits β-catenin/TCF signaling by redirecting β-catenin to the cell membrane. Biol Cell 100: 167-177.
    • (2007) Biol Cell , vol.100 , pp. 167-177
    • Bernard, P.1    Fleming, A.2    Lacombe, A.3    Harley, V.R.4    Vilain, E.5
  • 22
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context
    • Mikels AJ, Nusse R, (2006) Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context. PLoS Biol 4: e115.
    • (2006) PLoS Biol , vol.4
    • Mikels, A.J.1    Nusse, R.2
  • 23
    • 0028004304 scopus 로고
    • Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development
    • Tsai S, Bartelmez S, Sitnicka E, Collins S, (1994) Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development. Genes Dev 8: 2831-2841.
    • (1994) Genes Dev , vol.8 , pp. 2831-2841
    • Tsai, S.1    Bartelmez, S.2    Sitnicka, E.3    Collins, S.4
  • 24
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of β-catenin during canonical Wnt signaling
    • Wu X, Tu X, Joeng KS, Hilton MJ, Williams DA, et al. (2008) Rac1 activation controls nuclear localization of β-catenin during canonical Wnt signaling. Cell 133: 340-353.
    • (2008) Cell , vol.133 , pp. 340-353
    • Wu, X.1    Tu, X.2    Joeng, K.S.3    Hilton, M.J.4    Williams, D.A.5
  • 25
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: a double-edged sword in tumorigenesis
    • Eferl R, Wagner EF, (2003) AP-1: a double-edged sword in tumorigenesis. Nat Rev Cancer 3: 859-868.
    • (2003) Nat Rev Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 26
    • 0035971436 scopus 로고    scopus 로고
    • Partners in transcription: NFAT and AP-1
    • Macian F, Lopez-Rodriguez C, Rao A, (2001) Partners in transcription: NFAT and AP-1. Oncogene 20: 2476-2489.
    • (2001) Oncogene , vol.20 , pp. 2476-2489
    • Macian, F.1    Lopez-Rodriguez, C.2    Rao, A.3
  • 27
    • 34249679309 scopus 로고    scopus 로고
    • Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties
    • Bowie MB, Kent DG, Dykstra B, McKnight KD, McCaffrey L, et al. (2007) Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties. Proc Natl Acad Sci USA 104: 5878-5882.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5878-5882
    • Bowie, M.B.1    Kent, D.G.2    Dykstra, B.3    McKnight, K.D.4    McCaffrey, L.5
  • 29
    • 7044269527 scopus 로고    scopus 로고
    • JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells
    • Passegue E, Wagner EF, Weissman IL, (2004) JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell 119: 431-443.
    • (2004) Cell , vol.119 , pp. 431-443
    • Passegue, E.1    Wagner, E.F.2    Weissman, I.L.3
  • 30
    • 0033118607 scopus 로고    scopus 로고
    • The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development
    • Kuan CY, Yang DD, Samanta Roy DR, Davis RJ, Rakic P, et al. (1999) The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development. Neuron 22: 667-676.
    • (1999) Neuron , vol.22 , pp. 667-676
    • Kuan, C.Y.1    Yang, D.D.2    Samanta Roy, D.R.3    Davis, R.J.4    Rakic, P.5
  • 31
    • 0035808769 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation
    • Sabapathy K, Kallunki T, David JP, Graef I, Karin M, et al. (2001) c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation. J Exp Med 193: 317-328.
    • (2001) J Exp Med , vol.193 , pp. 317-328
    • Sabapathy, K.1    Kallunki, T.2    David, J.P.3    Graef, I.4    Karin, M.5
  • 32
    • 0034604093 scopus 로고    scopus 로고
    • JNK is required for effector T-cell function but not for T-cell activation
    • Dong C, Yang DD, Tournier C, Whitmarsh AJ, Xu J, et al. (2000) JNK is required for effector T-cell function but not for T-cell activation. Nature 405: 91-94.
    • (2000) Nature , vol.405 , pp. 91-94
    • Dong, C.1    Yang, D.D.2    Tournier, C.3    Whitmarsh, A.J.4    Xu, J.5
  • 33
    • 15244345063 scopus 로고    scopus 로고
    • Frizzled 9 knockout mice have abnormal B cell development
    • Ranheim EA, Kwan HC, Reya T, Wang Y-K, Weissman IL, et al. (2005) Frizzled 9 knockout mice have abnormal B cell development. Blood 105: 2487-2494.
    • (2005) Blood , vol.105 , pp. 2487-2494
    • Ranheim, E.A.1    Kwan, H.C.2    Reya, T.3    Wang, Y.-K.4    Weissman, I.L.5
  • 35
    • 2442548880 scopus 로고    scopus 로고
    • The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt-β-catenin signaling cascade
    • Golan T, Yaniv A, Bafico A, Liu G, Gazit A, (2004) The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt-β-catenin signaling cascade. J Biol Chem 279: 14879-14888.
    • (2004) J Biol Chem , vol.279 , pp. 14879-14888
    • Golan, T.1    Yaniv, A.2    Bafico, A.3    Liu, G.4    Gazit, A.5
  • 36
    • 3242681470 scopus 로고    scopus 로고
    • Wnt-4 activates the canonical β-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/β-catenin activity in kidney epithelial cells
    • Lyons JP, Mueller UW, Ji H, Everett C, Fang X, et al. (2004) Wnt-4 activates the canonical β-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/β-catenin activity in kidney epithelial cells. Exp Cell Res 298: 369-387.
    • (2004) Exp Cell Res , vol.298 , pp. 369-387
    • Lyons, J.P.1    Mueller, U.W.2    Ji, H.3    Everett, C.4    Fang, X.5
  • 37
    • 79751515852 scopus 로고    scopus 로고
    • Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2
    • Gao B, Song H, Bishop K, Elliot G, Garrett L, et al. (2011) Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2. Dev Cell 20: 163-176.
    • (2011) Dev Cell , vol.20 , pp. 163-176
    • Gao, B.1    Song, H.2    Bishop, K.3    Elliot, G.4    Garrett, L.5
  • 38
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L, Huang H, He X, et al. (2003) Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425: 836-841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3    Huang, H.4    He, X.5
  • 39
    • 0242268524 scopus 로고    scopus 로고
    • Osteoblastic cells regulate the haematopoietic stem cell niche
    • Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, et al. (2003) Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425: 841-846.
    • (2003) Nature , vol.425 , pp. 841-846
    • Calvi, L.M.1    Adams, G.B.2    Weibrecht, K.W.3    Weber, J.M.4    Olson, D.P.5
  • 40
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, et al. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121: 1109-1121.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Yilmaz, O.H.4    Terhorst, C.5
  • 41
    • 21244472780 scopus 로고    scopus 로고
    • Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
    • Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, et al. (2005) Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med 201: 1781-1791.
    • (2005) J Exp Med , vol.201 , pp. 1781-1791
    • Stier, S.1    Ko, Y.2    Forkert, R.3    Lutz, C.4    Neuhaus, T.5
  • 42
    • 70449706222 scopus 로고    scopus 로고
    • On the adaptation of endosteal stem cell niche function in response to stress
    • Jiang Y, Bonig H, Ulyanova T, Chang K, Papayannopoulou T, (2009) On the adaptation of endosteal stem cell niche function in response to stress. Blood 114: 3773-3782.
    • (2009) Blood , vol.114 , pp. 3773-3782
    • Jiang, Y.1    Bonig, H.2    Ulyanova, T.3    Chang, K.4    Papayannopoulou, T.5
  • 44
    • 77957020167 scopus 로고    scopus 로고
    • The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche
    • Omatsu Y, Sugiyama T, Kohara H, Kondoh G, Fujii N, et al. (2010) The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche. Immunity 33: 387-399.
    • (2010) Immunity , vol.33 , pp. 387-399
    • Omatsu, Y.1    Sugiyama, T.2    Kohara, H.3    Kondoh, G.4    Fujii, N.5
  • 45
    • 35648990464 scopus 로고    scopus 로고
    • Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK
    • Chang J, Sonoyama W, Wang Z, Jin Q, Zhang C, et al. (2007) Noncanonical Wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK. J Biol Chem 282: 30938-30948.
    • (2007) J Biol Chem , vol.282 , pp. 30938-30948
    • Chang, J.1    Sonoyama, W.2    Wang, Z.3    Jin, Q.4    Zhang, C.5
  • 46
    • 61849095684 scopus 로고    scopus 로고
    • JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation
    • Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, et al. (2009) JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation. J Bone Miner Res 24: 398-410.
    • (2009) J Bone Miner Res , vol.24 , pp. 398-410
    • Matsuguchi, T.1    Chiba, N.2    Bandow, K.3    Kakimoto, K.4    Masuda, A.5
  • 47
    • 70349574479 scopus 로고    scopus 로고
    • Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation
    • Dominici M, Rasini V, Bussolari R, Chen X, Hofmann TJ, et al. (2009) Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation. Blood 114: 2333-2343.
    • (2009) Blood , vol.114 , pp. 2333-2343
    • Dominici, M.1    Rasini, V.2    Bussolari, R.3    Chen, X.4    Hofmann, T.J.5
  • 48
    • 66149183002 scopus 로고    scopus 로고
    • beta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells
    • Nemeth MJ, Mak KK, Yang Y, Bodine DM, (2009) beta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells. Stem Cells 27: 1109-1119.
    • (2009) Stem Cells , vol.27 , pp. 1109-1119
    • Nemeth, M.J.1    Mak, K.K.2    Yang, Y.3    Bodine, D.M.4
  • 49
    • 58749092353 scopus 로고    scopus 로고
    • Soluble Frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis
    • Yokota T, Oritani K, Garrett KP, Kouro T, Nishida M, et al. (2008) Soluble Frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis. J Immunol 181: 6061-6072.
    • (2008) J Immunol , vol.181 , pp. 6061-6072
    • Yokota, T.1    Oritani, K.2    Garrett, K.P.3    Kouro, T.4    Nishida, M.5
  • 50
    • 77956449328 scopus 로고    scopus 로고
    • An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity
    • Hope KJ, Cellot S, Ting SB, MacRae T, Mayotte N, et al. (2010) An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell 7: 101-113.
    • (2010) Cell Stem Cell , vol.7 , pp. 101-113
    • Hope, K.J.1    Cellot, S.2    Ting, S.B.3    MacRae, T.4    Mayotte, N.5
  • 51
    • 77956608212 scopus 로고    scopus 로고
    • The endocytic adaptor Numb regulates thymus size by modulating pre-TCR signaling during asymmetric division
    • Aguado R, Martin-Blanco N, Caraballo M, Canelles M, (2010) The endocytic adaptor Numb regulates thymus size by modulating pre-TCR signaling during asymmetric division. Blood 116: 1705-1714.
    • (2010) Blood , vol.116 , pp. 1705-1714
    • Aguado, R.1    Martin-Blanco, N.2    Caraballo, M.3    Canelles, M.4
  • 52
    • 64249099616 scopus 로고    scopus 로고
    • A functional screen to identify novel effectors of hematopoietic stem cell activity
    • Deneault E, Cellot S, Faubert A, Laverdure JP, Frechette M, et al. (2009) A functional screen to identify novel effectors of hematopoietic stem cell activity. Cell 137: 369-379.
    • (2009) Cell , vol.137 , pp. 369-379
    • Deneault, E.1    Cellot, S.2    Faubert, A.3    Laverdure, J.P.4    Frechette, M.5
  • 53
    • 0032126633 scopus 로고    scopus 로고
    • Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
    • Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, et al. (1998) Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J 17: 3714-3725.
    • (1998) EMBO J , vol.17 , pp. 3714-3725
    • Kroon, E.1    Krosl, J.2    Thorsteinsdottir, U.3    Baban, S.4    Buchberg, A.M.5
  • 54
    • 33846706250 scopus 로고    scopus 로고
    • Prediction of graft-versus-host disease in humans by donor gene expression profiling
    • Baron C, Somogyi R, Greller LD, Rineau V, Wilkinson P, et al. (2007) Prediction of graft-versus-host disease in humans by donor gene expression profiling. PLoS Med 4: e23.
    • (2007) PLoS Med , vol.4
    • Baron, C.1    Somogyi, R.2    Greller, L.D.3    Rineau, V.4    Wilkinson, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.