-
1
-
-
0035811625
-
Hepatitis C virus infection
-
Lauer GM, Walker BD. Hepatitis C virus infection. N Engl J Med 2001; 345:41-52.
-
(2001)
N Engl J Med
, vol.345
, pp. 41-52
-
-
Lauer, G.M.1
Walker, B.D.2
-
3
-
-
68849111675
-
Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence
-
Rehermann B. Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence. J Clin Invest 2009; 119:1745-54.
-
(2009)
J Clin Invest
, vol.119
, pp. 1745-1754
-
-
Rehermann, B.1
-
4
-
-
36348988986
-
T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts and controversies
-
Manigold T, Racanelli V. T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts and controversies. Lancet Infect Dis 2007; 7:804-13.
-
(2007)
Lancet Infect Dis
, vol.7
, pp. 804-813
-
-
Manigold, T.1
Racanelli, V.2
-
5
-
-
33745876557
-
Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses
-
Urbani S, Amadei B, Fisicaro P etal. Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses. Hepatology 2006; 44:126-39.
-
(2006)
Hepatology
, vol.44
, pp. 126-139
-
-
Urbani, S.1
Amadei, B.2
Fisicaro, P.3
-
6
-
-
77957926607
-
HCV+ hepatocytes induce human regulatory CD4+ T cells through the production of TGF-beta
-
Hall CH, Kassel R, Tacke RS, Hahn YS. HCV+ hepatocytes induce human regulatory CD4+ T cells through the production of TGF-beta. PLoS ONE 2010; 5:e12154.
-
(2010)
PLoS ONE
, vol.5
-
-
Hall, C.H.1
Kassel, R.2
Tacke, R.S.3
Hahn, Y.S.4
-
7
-
-
0013912854
-
Pooling of platelets in the spleen: role in the pathogenesis of 'hypersplenic' thrombocytopenia
-
Aster RH. Pooling of platelets in the spleen: role in the pathogenesis of 'hypersplenic' thrombocytopenia. J Clin Invest 1966; 45:645-57.
-
(1966)
J Clin Invest
, vol.45
, pp. 645-657
-
-
Aster, R.H.1
-
8
-
-
35448975065
-
Review article: the pathophysiology of thrombocytopenia in hepatitis C virus infection and chronic liver disease
-
Weksler BB. Review article: the pathophysiology of thrombocytopenia in hepatitis C virus infection and chronic liver disease. Aliment Pharmacol Ther 2007; 26 (Suppl. 1):13-19.
-
(2007)
Aliment Pharmacol Ther
, vol.26
, Issue.1 SUPPL.
, pp. 13-19
-
-
Weksler, B.B.1
-
9
-
-
0036829986
-
Treatment of chronic hepatitis C: a systematic review
-
Chander G, Sulkowski MS, Jenckes MW etal. Treatment of chronic hepatitis C: a systematic review. Hepatology 2002; 36:S135-44.
-
(2002)
Hepatology
, vol.36
-
-
Chander, G.1
Sulkowski, M.S.2
Jenckes, M.W.3
-
10
-
-
7044263003
-
Prevention of hepatitis C virus-related hepatocellular carcinoma
-
Heathcote EJ. Prevention of hepatitis C virus-related hepatocellular carcinoma. Gastroenterology 2004; 127:S294-302.
-
(2004)
Gastroenterology
, vol.127
-
-
Heathcote, E.J.1
-
12
-
-
0034619980
-
Peginterferon alfa-2a in patients with chronic hepatitis C and cirrhosis
-
Heathcote EJ, Shiffman ML, Cooksley WG etal. Peginterferon alfa-2a in patients with chronic hepatitis C and cirrhosis. N Engl J Med 2000; 343:1673-80.
-
(2000)
N Engl J Med
, vol.343
, pp. 1673-1680
-
-
Heathcote, E.J.1
Shiffman, M.L.2
Cooksley, W.G.3
-
13
-
-
0034619946
-
Peginterferon alfa-2a in patients with chronic hepatitis C
-
Zeuzem S, Feinman SV, Rasenack J etal. Peginterferon alfa-2a in patients with chronic hepatitis C. N Engl J Med 2000; 343:1666-72.
-
(2000)
N Engl J Med
, vol.343
, pp. 1666-1672
-
-
Zeuzem, S.1
Feinman, S.V.2
Rasenack, J.3
-
14
-
-
33748445531
-
Splenectomy for thrombocytopenia in patients with hepatitis C cirrhosis
-
Hayashi PH, Mehia C, Joachim Reimers H, Solomon HS, Bacon BR. Splenectomy for thrombocytopenia in patients with hepatitis C cirrhosis. J Clin Gastroenterol 2006; 40:740-4.
-
(2006)
J Clin Gastroenterol
, vol.40
, pp. 740-744
-
-
Hayashi, P.H.1
Mehia, C.2
Joachim Reimers, H.3
Solomon, H.S.4
Bacon, B.R.5
-
15
-
-
53749106612
-
Splenectomy for thrombocytopenia in patients with hepatitis C cirrhosis
-
Davern TJ. Splenectomy for thrombocytopenia in patients with hepatitis C cirrhosis. J Clin Gastroenterol 2008; 42:863-4.
-
(2008)
J Clin Gastroenterol
, vol.42
, pp. 863-864
-
-
Davern, T.J.1
-
16
-
-
75449089682
-
CX3CL1 (fractalkine): a signpost for biliary inflammation in primary biliary cirrhosis
-
Shimoda S, Harada K, Niiro H etal. CX3CL1 (fractalkine): a signpost for biliary inflammation in primary biliary cirrhosis. Hepatology 2010; 51:567-75.
-
(2010)
Hepatology
, vol.51
, pp. 567-575
-
-
Shimoda, S.1
Harada, K.2
Niiro, H.3
-
17
-
-
23944467250
-
Adaptive immune responses in acute and chronic hepatitis C virus infection
-
Bowen DG, Walker CM. Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature 2005; 436:946-52.
-
(2005)
Nature
, vol.436
, pp. 946-952
-
-
Bowen, D.G.1
Walker, C.M.2
-
18
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber DL, Wherry EJ, Masopust D etal. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006; 439:682-7.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
-
19
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
Fife BT, Pauken KE, Eagar TN etal. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol 2009; 10:1185-92.
-
(2009)
Nat Immunol
, vol.10
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
-
20
-
-
24944509220
-
T cells and viral persistence: lessons from diverse infections
-
Klenerman P, Hill A. T cells and viral persistence: lessons from diverse infections. Nat Immunol 2005; 6:873-9.
-
(2005)
Nat Immunol
, vol.6
, pp. 873-879
-
-
Klenerman, P.1
Hill, A.2
-
21
-
-
33645846313
-
Tissue expression of PD-L1 mediates peripheral T cell tolerance
-
Keir ME, Liang SC, Guleria I etal. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med 2006; 203:883-95.
-
(2006)
J Exp Med
, vol.203
, pp. 883-895
-
-
Keir, M.E.1
Liang, S.C.2
Guleria, I.3
-
22
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman Y, Wood CR, Chernova T etal. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2001; 2:261-8.
-
(2001)
Nat Immunol
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
-
23
-
-
19944370822
-
T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection
-
Boettler T, Spangenberg HC, Neumann-Haefelin C etal. T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. J Virol 2005; 79:7860-7.
-
(2005)
J Virol
, vol.79
, pp. 7860-7867
-
-
Boettler, T.1
Spangenberg, H.C.2
Neumann-Haefelin, C.3
-
24
-
-
21344442507
-
Cellular immune selection with hepatitis C virus persistence in humans
-
Cox AL, Mosbruger T, Mao Q etal. Cellular immune selection with hepatitis C virus persistence in humans. J Exp Med 2005; 201:1741-52.
-
(2005)
J Exp Med
, vol.201
, pp. 1741-1752
-
-
Cox, A.L.1
Mosbruger, T.2
Mao, Q.3
-
25
-
-
0037105567
-
Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
-
Wedemeyer H, He XS, Nascimbeni M etal. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J Immunol 2002; 169:3447-58.
-
(2002)
J Immunol
, vol.169
, pp. 3447-3458
-
-
Wedemeyer, H.1
He, X.S.2
Nascimbeni, M.3
-
26
-
-
7044247947
-
An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection
-
Cabrera R, Tu Z, Xu Y etal. An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. Hepatology 2004; 40:1062-71.
-
(2004)
Hepatology
, vol.40
, pp. 1062-1071
-
-
Cabrera, R.1
Tu, Z.2
Xu, Y.3
-
27
-
-
43249107955
-
Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection
-
Ebinuma H, Nakamoto N, Li Y etal. Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection. J Virol 2008; 82:5043-53.
-
(2008)
J Virol
, vol.82
, pp. 5043-5053
-
-
Ebinuma, H.1
Nakamoto, N.2
Li, Y.3
-
28
-
-
44849113503
-
Cutting edge: programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: race-dependent differences
-
Golden-Mason L, Klarquist J, Wahed AS, Rosen HR. Cutting edge: programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: race-dependent differences. J Immunol 2008; 180:3637-41.
-
(2008)
J Immunol
, vol.180
, pp. 3637-3641
-
-
Golden-Mason, L.1
Klarquist, J.2
Wahed, A.S.3
Rosen, H.R.4
-
29
-
-
58149380829
-
Pretreatment prediction of virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients using viral and host factors
-
Shirakawa H, Matsumoto A, Joshita S etal. Pretreatment prediction of virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients using viral and host factors. Hepatology 2008; 48:1753-60.
-
(2008)
Hepatology
, vol.48
, pp. 1753-1760
-
-
Shirakawa, H.1
Matsumoto, A.2
Joshita, S.3
-
30
-
-
0033136306
-
Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals
-
Kanto T, Hayashi N, Takehara T etal. Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals. J Immunol 1999; 162:5584-91.
-
(1999)
J Immunol
, vol.162
, pp. 5584-5591
-
-
Kanto, T.1
Hayashi, N.2
Takehara, T.3
-
31
-
-
39549097752
-
Cell culture-produced hepatitis C virus impairs plasmacytoid dendritic cell function
-
Shiina M, Rehermann B. Cell culture-produced hepatitis C virus impairs plasmacytoid dendritic cell function. Hepatology 2008; 47:385-95.
-
(2008)
Hepatology
, vol.47
, pp. 385-395
-
-
Shiina, M.1
Rehermann, B.2
-
32
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003; 4:330-6.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
33
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299:1057-61.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
34
-
-
41149112957
-
Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection
-
Ha SJ, Mueller SN, Wherry EJ etal. Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. J Exp Med 2008; 205:543-55.
-
(2008)
J Exp Med
, vol.205
, pp. 543-555
-
-
Ha, S.J.1
Mueller, S.N.2
Wherry, E.J.3
-
35
-
-
44449143022
-
Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model
-
Lukens JR, Cruise MW, Lassen MG, Hahn YS. Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model. J Immunol 2008; 180:4875-84.
-
(2008)
J Immunol
, vol.180
, pp. 4875-4884
-
-
Lukens, J.R.1
Cruise, M.W.2
Lassen, M.G.3
Hahn, Y.S.4
-
36
-
-
53049099600
-
PD-1 ligand expression by human colonic myofibroblasts/fibroblasts regulates CD4+ T-cell activity
-
37 e1-2
-
Pinchuk IV, Saada JI, Beswick EJ etal. PD-1 ligand expression by human colonic myofibroblasts/fibroblasts regulates CD4+ T-cell activity. Gastroenterology 2008; 135:1228-37, 37 e1-2.
-
(2008)
Gastroenterology
, vol.135
, pp. 1228-1237
-
-
Pinchuk, I.V.1
Saada, J.I.2
Beswick, E.J.3
-
37
-
-
72949086641
-
Chronically inflamed livers up-regulate expression of inhibitory B7 family members
-
Kassel R, Cruise MW, Iezzoni JC, Taylor NA, Pruett TL, Hahn YS. Chronically inflamed livers up-regulate expression of inhibitory B7 family members. Hepatology 2009; 50:1625-37.
-
(2009)
Hepatology
, vol.50
, pp. 1625-1637
-
-
Kassel, R.1
Cruise, M.W.2
Iezzoni, J.C.3
Taylor, N.A.4
Pruett, T.L.5
Hahn, Y.S.6
-
38
-
-
0242559053
-
Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis
-
Rodig N, Ryan T, Allen JA etal. Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis. Eur J Immunol 2003; 33:3117-26.
-
(2003)
Eur J Immunol
, vol.33
, pp. 3117-3126
-
-
Rodig, N.1
Ryan, T.2
Allen, J.A.3
|