Splenectomy for thrombocytopenia in patients with hepatitis C cirrhosis

Journal of Clinical Gastroenterology

Volumn 42, Issue 7, 2008, Pages 863-864

  Davern, Timothy J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELTROMBOPAG; ALPHA2B INTERFERON; ANTIVIRUS AGENT;

DRUG TOLERABILITY; HAEMOPHILUS INFLUENZAE; HEPATITIS C; HUMAN; INFECTION RISK; LETTER; LIVER CIRRHOSIS; MORBIDITY; MULTIPLE ORGAN FAILURE; PRIORITY JOURNAL; SEPSIS; SPLENECTOMY; STREPTOCOCCUS PNEUMONIAE; THROMBOCYTOPENIA; UNSPECIFIED SIDE EFFECT; VACCINATION; MICROBIOLOGY; NOTE;

ANTIVIRAL AGENTS; HEPATITIS C, CHRONIC; HUMANS; INTERFERON ALFA-2B; LIVER CIRRHOSIS; SEPSIS; SPLENECTOMY; THROMBOCYTOPENIA;

EID: 53749106612     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/MCG.0b013e318033f96e     Document Type: Letter

References (5)

1. Hayashi PH, Mehia C, Joachim Reimers H, et al. Splenectomy for thrombocytopenia in patients with hepatitis C cirrhosis. J Clin Gastroenterol. 2006;40:740-744.
2. el-Khishen MA, Henderson JM, Millikan WJ Jr, et al. Splenectomy is contraindicated for thrombocytopenia secondary to portal hypertension. Surg Gynecol Obstet. 1985; 160:233-238.
3. Davidson RN, Wall RA. Prevention and management of infections in patients without a spleen. Clin Microbiol Infect. 2001;7:657-660.
4. Waghorn DJ. Overwhelming infection in asplenic patients: current best practice preventive measures are not being followed. J Clin Pathol. 2001;54:2214-2218.
5. McHutchison JG, Afdhal NH, Dusheiko G, et al. Eltrombopag, an oral platelet growth factor, facilitates initiation of interferon therapy in subjects with HCV associated thrombocytopenia: results from a phase II placebo controlled, double-blind, dose-ranging study. Hepatology. 2006;44:692-3A.