Metabolism of dl-praeruptorin A in rat liver microsomes using HPLC-electrospray ionization tandem mass spectrometry

Archives of Pharmacal Research

Volumn 34, Issue 8, 2011, Pages 1311-1321

  Ruan, Hang ^a   Zhang, Zhen ^a   Liang, Xin Fang ^a   Fu, Yan ^a   Su, Mei Qin ^a   Liu, Qi Lin ^a   Wang, Xiu Min ^a   Zhu, Xuan ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

Cytochrome P450 isoforms; Dl Praeruptorin A; HPLC ESI MS n; In vitro; Metabolites; Rat liver microsomes

Indexed keywords

ALPHA NAPHTHOFLAVONE; BETA NAPHTHOFLAVONE; CYTOCHROME P450; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; DEXAMETHASONE; DISULFIRAM; DL PRAERUPTORIN A; DRUG METABOLITE; FLUINDOSTATIN; HERBACEOUS AGENT; KETOCONAZOLE; METYRAPONE; PHENOBARBITAL; PROADIFEN; QUINIDINE; TICLOPIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG METABOLISM; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; LIVER MICROSOME; NONHUMAN; RAT;

ANIMALS; CARDIOVASCULAR AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG INTERACTIONS; DRUGS, CHINESE HERBAL; ENZYME INDUCTION; ENZYME INHIBITORS; HYDROXYLATION; ISOENZYMES; MALE; MEMBRANE PROTEINS; MICROSOMES, LIVER; MOLECULAR STRUCTURE; PROADIFEN; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 80855140921     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0811-y     Document Type: Article

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