Effects of dl-praeruptorin A on cultured neonatal rat ventricular cardiomyocytes with hypertrophy induced by endothelin-1

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 31, Issue 4, 2009, Pages 231-236

  Tu, X ^a   Miao, L ^b   Kang, Y ^b   Xia, H ^c   Tu, J W ^d   Wang, Q ^a   Tu, Q ^e   Wang, J M ^c   Hao, Huang ^f  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Angiocardiopathy Internal Department   (China)

^c WUHAN UNIVERSITY   (China)

^d HUBEI UNIVERSITY OF CHINESE MEDICINE   (China)

^e JIANGHAN UNIVERSITY   (China)

^f WUHAN NO 1 HOSPITAL   (China)

Author keywords

Cardiomyocyte hypertrophy; dl Praeruptorin A; Endothelin 1; Mitogen activated protein kinase pathway

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; ENDOTHELIN 1; LEUCINE; MITOGEN ACTIVATED PROTEIN KINASE; PRAERUPTORIN; PROTEIN BAX; PROTEIN BCL 2; PYRANOCOUMARIN DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; CALCIUM; COUMARIN DERIVATIVE; HERBACEOUS AGENT; PRAERUPTORIN A; PROTEIN C JUN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL SURFACE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MEDICINAL PLANT; NEWBORN; NONHUMAN; PEUCEDANUM PRAERUPTORUM; PLANT ROOT; PROTEIN SYNTHESIS; RAT; ANIMAL; CARDIOMEGALY; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; GENETICS; HEART CONTRACTION; HEART VENTRICLE; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM; CARDIOMEGALY; CELLS, CULTURED; COUMARINS; DRUGS, CHINESE HERBAL; ENDOTHELIN-1; GENE EXPRESSION REGULATION; HEART VENTRICLES; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 69849094954     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2009.31.4.1371199     Document Type: Article

References (24)

1. Kozawa, T., Sakai, K., Uchida, M., Okuyama, T., Shibata S. Calcium antagonistic action of a coumarin isolated from "Qian-Hu", a Chinese traditional medicine. J Pharm Pharmacol 1981, 33(5): 317-320
2. Wu, J., Fong, W-F., Zhang, J-X. et al. Reversal of multidrug resistance in cancer cells by pyranocoumarins isolated from Radix Peucedani. Eur J Pharmacol 2003, 473(1): 9-17.
3. Lu, M., Nicoletti, M., Battinelli, L., Mazzanti, G. Isolation of praeruptorins A and B from Peucedanum praeruptorum Dunn. and their general pharmacological evaluation in comparison with extracts of the drug. Farmaco 2001, 56: 417-420
4. Zhang, J-X., Fong, W-F., Wu, J-Y., Yang M., Cheung, H-Y. Pyranocoumarins isolated from Peucedanum praeruptorum as differentiation inducers in human leukemic HL-60 cells. Planta Med 2003, 69(3): 223-229
5. Ye, W-P., Ge, Z-D., Liu, G-H. The extraction and separation of Pd-Ia from the Chinese herb Peucedanum praeruptorum Dunn. J China Med Univ 1996, 25(4): 351-354
6. Iwaki, K., Sukhatme, V., Shubeita, H., Chien, K. α- And β-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. J Biol Chem 1990, 265(23): 13809-13817
7. Sugden, P.H. An overview of endothelin signaling in the cardiac myocyte. J Mol Cell Cardiol 2003, 35(8): 871-886
8. Sadoshima, J., Xu, Y., Slayter, H.S., Izumo, S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 1993, 75(5): 977-984 (Pubitemid 24014554)
9. Ito, H., Hirata, Y., Adachi, S. et al. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 1993, 92(1): 398-403.
10. Liang, F., Gardner, D.G. Autocrine/paracrine determinants of strain-activated brain natriuretic peptide gene expression in cultured cardiac myocytes. J Biol Chem 1998, 273(23): 14612-14619
11. Dunnmon, P.M., Iwaki, K., Henderson, S.A., Sen, A., Chien, K.R. Phorbol esters induce immediate-early genes and activate cardiac gene transcription in neonatal rat myocardial cells. J Mol Cell Cardiol 1990, 22(8): 901-910
12. Tramontano, A.F., Muniyappa, R., Black, A.D. et al. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem Biophys Res Commun 2003, 308(4): 990-994
13. Dragunow, M., Preston, K. The role of inducible transcription factors in apoptotic nerve cell death. Brain Res Rev 1995, 21(1): 1-28.
14. Hughes, P., Dragunow, M. Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol Rev 1995, 47(1): 133-178
15. Krown, K.A., Page, M.T., Nguyen, C. et al. Tumor necrosis factor alphainduced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. J Clin Invest 1996, 98(12): 2854-2865
16. Sheng, M., Greenberg, M.E. The regulation and function of c-fos and other immediate-early genes in the nervous system. Neuron 1990, 4(4): 477-485
17. Yang, H.Y., Liu, J.C., Chen, Y.L. et al. Inhibitory effect of trilinolein on endothelin-1-induced c-fos gene expression in cultured neonatal rat cardiomyocytes. Naunyn Schmiedebergs Arch Pharmacol 2005, 372(2): 160-167
18. Cheng, T.H., Shih, N.L., Chen, C.H. et al. Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced beta-myosin heavy chain gene expression and cardiomyocyte hypertrophy. J Biomed Sci 2005, 12(1): 123-133
19. Irukayama-Tomobe, Y., Miyauchi, T., Sakai, S. et al. Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferatoractivated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway. Circulation 2004, 109(7): 904-910
20. Molostvov, G., James, S., Fletcher, S., Bennett, J., Lehnert, H., Bland, R., Zehnder, D. Extracellular calcium-sensing receptor is functionally expressed in human artery. Am J Physiol Renal Physiol 2007, 293(3): 946-955
21. Edwards, C., Armstrong, P., Goode, G., Mtshali, C., Williams, S., Myles, E.L., Washington, B. Cross-talking between calcium and histamine in the expression of MAPKs in hypertensive vascular smooth muscle cells. Cell Mol Biol (Noisy-le-grand) 2007, 53(4): 61-66
22. Menick, D.R., Renaud, L., Buchholz, A. et al. Regulation of Ncx1 gene expression in the normal and hypertrophic heart. Ann NY Acad Sci 2007, 1099: 195-203.
23. Nodai, A., Machida, T., Izumi, S. et al. Sphingosine 1-phosphate induces cyclooxygenase-2 via Ca2+-dependent, but MAPK-independent mechanism in rat vascular smooth muscle cells. Life Sci 2007, 80(19): 1768-1776
24. Wang, G., Kawakami, K., Gick, G. Divergent signaling pathways mediate induction of Na,K-ATPase alpha1 and beta1 subunit gene transcription by low potassium. Mol Cell Biochem 2007, 294(1-2): 73-85.