Concordant up-regulation of cytochrome P450 Cyp3a11, testosterone oxidation and androgen receptor expression in mouse brain after xenobiotic treatment

Journal of Neurochemistry

Volumn 109, Issue 2, 2009, Pages 670-681

  Meyer, Ralf Peter ^a,b   Gehlhaus, Marcel ^b   Schwab, Ricarda ^b,c   Bürck, Carolin ^b,c   Knoth, Rolf ^b   Hagemeyer, Christoph Eugen ^d  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c FURTWANGEN UNIVERSITY   (Germany)

^d BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Androgen receptor; CYP3A 2B; Cytochrome P450; Mouse brain; PC 12 cells; Phenytoin; Testosterone metabolism

Indexed keywords

15ALPHA HYDROXYTESTOSTERONE; 16ALPHA HYDROXYTESTOSTERONE; 16BETA HYDROXYTESTOSTERONE; 2ALPHA HYDROXYTESTOSTERONE; 2BETA HYDROXYTESTOSTERONE; 6BETA HYDROXYTESTOSTERONE; ANDROGEN RECEPTOR; ANTIBODY; CHLORAMPHENICOL; CYTOCHROME P450 2B; CYTOCHROME P450 2B9; CYTOCHROME P450 3A; CYTOCHROME P450 3A11; KETOCONAZOLE; NIFEDIPINE; ORPHENADRINE; PHENYTOIN; TESTOSTERONE; TESTOSTERONE DERIVATIVE; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME REGULATION; HIPPOCAMPUS; HORMONE INHIBITION; HORMONE RESPONSE; HYDROXYLATION; HYPOTHALAMUS; LIMBIC SYSTEM; MALE; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TESTOSTERONE METABOLISM; THALAMUS;

ANIMALS; BRAIN; CYTOCHROME P-450 CYP3A; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MEMBRANE PROTEINS; METABOLIC DETOXICATION, DRUG; MICE; MICE, INBRED C57BL; OXIDATION-REDUCTION; PC12 CELLS; RATS; RECEPTORS, ANDROGEN; TESTOSTERONE; TIME FACTORS; UP-REGULATION; XENOBIOTICS;

EID: 62649093460     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.05994.x     Document Type: Article

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