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Volumn 79, Issue 11, 2011, Pages 4696-4707

Proteomic analysis of anaplasma phagocytophilum during infection of human myeloid cells identifies a protein that is pronouncedly upregulated on the infectious dense-cored cell

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; RNA;

EID: 80855140062     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.05658-11     Document Type: Article
Times cited : (41)

References (62)
  • 2
    • 0037378109 scopus 로고    scopus 로고
    • Expression of multiple outer membrane protein sequence variants from a single genomic locus of Anaplasma phagocytophilum
    • Barbet, A. F., et al. 2003. Expression of multiple outer membrane protein sequence variants from a single genomic locus of Anaplasma phagocytophilum. Infect. Immun. 71:1706-1718.
    • (2003) Infect. Immun. , vol.71 , pp. 1706-1718
    • Barbet, A.F.1
  • 3
    • 18744367006 scopus 로고    scopus 로고
    • Insights into pathogen immune evasion mechanisms: Anaplasma phagocytophilum fails to induce an apoptosis differentiation program in human neutrophils
    • Borjesson, D. L., et al. 2005. Insights into pathogen immune evasion mechanisms: Anaplasma phagocytophilum fails to induce an apoptosis differentiation program in human neutrophils. J. Immunol. 174:6364-6372.
    • (2005) J. Immunol. , vol.174 , pp. 6364-6372
    • Borjesson, D.L.1
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 33750620715 scopus 로고    scopus 로고
    • Laboratory maintenance of Anaplasma phagocytophilum
    • R. Coico, T. F. Kowalik, J. M. Quarles, B. Stevenson, and R. Taylor (ed.), J. Wiley and Sons, Hoboken, NJ
    • Carlyon, J. A. 2005. Laboratory maintenance of Anaplasma phagocytophilum, p. 3A.2.1-3A.2.30. In R. Coico, T. F. Kowalik, J. M. Quarles, B. Stevenson, and R. Taylor (ed.), Current protocols in microbiology. J. Wiley and Sons, Hoboken, NJ.
    • (2005) Current protocols in microbiology
    • Carlyon, J.A.1
  • 6
    • 0037114184 scopus 로고    scopus 로고
    • Repression of rac2 mRNA expression by Anaplasma phagocytophila is essential to the inhibition of superoxide production and bacterial proliferation
    • Carlyon, J. A., W. T. Chan, J. Galan, D. Roos, and E. Fikrig. 2002. Repression of rac2 mRNA expression by Anaplasma phagocytophila is essential to the inhibition of superoxide production and bacterial proliferation. J. Immunol. 169:7009-7018.
    • (2002) J. Immunol. , vol.169 , pp. 7009-7018
    • Carlyon, J.A.1    Chan, W.T.2    Galan, J.3    Roos, D.4    Fikrig, E.5
  • 7
    • 0033850294 scopus 로고    scopus 로고
    • ankA: an Ehrlichia phagocytophila group gene encoding a cytoplasmic protein antigen with ankyrin repeats
    • Caturegli, P., et al. 2000. ankA: an Ehrlichia phagocytophila group gene encoding a cytoplasmic protein antigen with ankyrin repeats. Infect. Immun. 68:5277-5283.
    • (2000) Infect. Immun. , vol.68 , pp. 5277-5283
    • Caturegli, P.1
  • 8
    • 0028079454 scopus 로고
    • Identification of the antigenic constituents of Ehrlichia chaffeensis
    • Chen, S. M., J. S. Dumler, H. M. Feng, and D. H. Walker. 1994. Identification of the antigenic constituents of Ehrlichia chaffeensis. Am. J. Trop. Med. Hyg. 50:52-58.
    • (1994) Am. J. Trop. Med. Hyg. , vol.50 , pp. 52-58
    • Chen, S.M.1    Dumler, J.S.2    Feng, H.M.3    Walker, D.H.4
  • 9
    • 33745771590 scopus 로고    scopus 로고
    • Intraleukocyte expression of two-component systems in Ehrlichia chaffeensis and Anaplasma phagocytophilum and effects of the histidine kinase inhibitor closantel
    • Cheng, Z., Y. Kumagai, M. Lin, C. Zhang, and Y. Rikihisa. 2006. Intraleukocyte expression of two-component systems in Ehrlichia chaffeensis and Anaplasma phagocytophilum and effects of the histidine kinase inhibitor closantel. Cell. Microbiol. 8:1241-1252.
    • (2006) Cell. Microbiol. , vol.8 , pp. 1241-1252
    • Cheng, Z.1    Kumagai, Y.2    Lin, M.3    Zhang, C.4    Rikihisa, Y.5
  • 10
    • 33750917844 scopus 로고    scopus 로고
    • Transformation of Anaplasma phagocytophilum
    • Felsheim, R. F., et al. 2006. Transformation of Anaplasma phagocytophilum. BMC Biotechnol. 6:42.
    • (2006) BMC Biotechnol , vol.6 , pp. 42
    • Felsheim, R.F.1
  • 11
    • 67650886021 scopus 로고    scopus 로고
    • Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum
    • Garcia-Garcia, J. C., N. C. Barat, S. J. Trembley, and J. S. Dumler. 2009. Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum. PLoS Pathog. 5:e1000488.
    • (2009) PLoS Pathog , vol.5
    • Garcia-Garcia, J.C.1    Barat, N.C.2    Trembley, S.J.3    Dumler, J.S.4
  • 12
    • 66549089938 scopus 로고    scopus 로고
    • Silencing of host cell CYBB gene expression by the nuclear effector AnkA of the intracellular pathogen Anaplasma phagocytophilum
    • Garcia-Garcia, J. C., K. E. Rennoll-Bankert, S. Pelly, A. M. Milstone, and J. S. Dumler. 2009. Silencing of host cell CYBB gene expression by the nuclear effector AnkA of the intracellular pathogen Anaplasma phagocytophilum. Infect. Immun. 77:2385-2391.
    • (2009) Infect. Immun. , vol.77 , pp. 2385-2391
    • Garcia-Garcia, J.C.1    Rennoll-Bankert, K.E.2    Pelly, S.3    Milstone, A.M.4    Dumler, J.S.5
  • 13
    • 63049084861 scopus 로고    scopus 로고
    • The detection, correlation, and comparison of peptide precursor and product ions from data independent LC-MS with data dependent LC-MS/MS
    • Geromanos, S. J., et al. 2009. The detection, correlation, and comparison of peptide precursor and product ions from data independent LC-MS with data dependent LC-MS/MS. Proteomics 9:1683-1695.
    • (2009) Proteomics , vol.9 , pp. 1683-1695
    • Geromanos, S.J.1
  • 14
    • 0030044553 scopus 로고    scopus 로고
    • Direct cultivation of the causative agent of human granulocytic ehrlichiosis
    • Goodman, J. L., et al. 1996. Direct cultivation of the causative agent of human granulocytic ehrlichiosis. N. Engl. J. Med. 334:209-215.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 209-215
    • Goodman, J.L.1
  • 15
    • 42149144628 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum infects cells of the megakaryocytic lineage through sialylated ligands but fails to alter platelet production
    • Granick, J. L., D. V. Reneer, J. A. Carlyon, and D. L. Borjesson. 2008. Anaplasma phagocytophilum infects cells of the megakaryocytic lineage through sialylated ligands but fails to alter platelet production. J. Med. Microbiol. 57:416-423.
    • (2008) J. Med. Microbiol. , vol.57 , pp. 416-423
    • Granick, J.L.1    Reneer, D.V.2    Carlyon, J.A.3    Borjesson, D.L.4
  • 16
    • 0027076709 scopus 로고
    • An improved procedure for the purification of protein fused with glutathione S-transferase
    • Grieco, F., J. M. Hay, and R. Hull. 1992. An improved procedure for the purification of protein fused with glutathione S-transferase. Biotechniques 13:856-858.
    • (1992) Biotechniques , vol.13 , pp. 856-858
    • Grieco, F.1    Hay, J.M.2    Hull, R.3
  • 17
    • 0030910616 scopus 로고    scopus 로고
    • Propagation of granulocytic Ehrlichia spp. from human and equine sources in HL-60 cells induced to differentiate into functional granulocytes
    • Heimer, R., A. Van Andel, G. P. Wormser, and M. L. Wilson. 1997. Propagation of granulocytic Ehrlichia spp. from human and equine sources in HL-60 cells induced to differentiate into functional granulocytes. J. Clin. Microbiol. 35:923-927.
    • (1997) J. Clin. Microbiol. , vol.35 , pp. 923-927
    • Heimer, R.1    Van Andel, A.2    Wormser, G.P.3    Wilson, M.L.4
  • 18
    • 33745713623 scopus 로고    scopus 로고
    • The interactions of Anaplasma phagocytophilum, endothelial cells, and human neutrophils
    • Herron, M. J., M. E. Ericson, T. J. Kurtti, and U. G. Munderloh. 2005. The interactions of Anaplasma phagocytophilum, endothelial cells, and human neutrophils. Ann. N. Y. Acad. Sci. 1063:374-382.
    • (2005) Ann. N. Y. Acad. Sci. , vol.1063 , pp. 374-382
    • Herron, M.J.1    Ericson, M.E.2    Kurtti, T.J.3    Munderloh, U.G.4
  • 19
    • 0034595997 scopus 로고    scopus 로고
    • Intracellular parasitism by the human granulocytic ehrlichiosis bacterium through the P-selectin ligand
    • Herron, M. J., et al. 2000. Intracellular parasitism by the human granulocytic ehrlichiosis bacterium through the P-selectin ligand, PSGL-1. Science 288: 1653-1656.
    • (2000) PSGL-1. Science , vol.288 , pp. 1653-1656
    • Herron, M.J.1
  • 20
    • 33645760951 scopus 로고    scopus 로고
    • Comparative genomics of emerging human ehrlichiosis agents
    • Hotopp, J. C., et al. 2006. Comparative genomics of emerging human ehrlichiosis agents. PLoS Genet. 2:e21.
    • (2006) PLoS Genet , vol.2
    • Hotopp, J.C.1
  • 21
    • 77955427023 scopus 로고    scopus 로고
    • The Anaplasma phagocytophilum-occupied vacuole selectively recruits Rab-GTPases that are predominantly associated with recycling endosomes
    • Huang, B., et al. 2010. The Anaplasma phagocytophilum-occupied vacuole selectively recruits Rab-GTPases that are predominantly associated with recycling endosomes. Cell. Microbiol. 12:1292-1307.
    • (2010) Cell. Microbiol. , vol.12 , pp. 1292-1307
    • Huang, B.1
  • 22
    • 77955427703 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum APH_0032 is expressed late during infection and localizes to the pathogen-occupied vacuolar membrane
    • Huang, B., et al. 2010. Anaplasma phagocytophilum APH_0032 is expressed late during infection and localizes to the pathogen-occupied vacuolar membrane. Microb. Pathog. 49:273-284.
    • (2010) Microb. Pathog. , vol.49 , pp. 273-284
    • Huang, B.1
  • 23
    • 77951215124 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum APH_1387 is expressed throughout bacterial intracellular development and localizes to the pathogen-occupied vacuolar membrane
    • Huang, B., et al. 2010. Anaplasma phagocytophilum APH_1387 is expressed throughout bacterial intracellular development and localizes to the pathogen-occupied vacuolar membrane. Infect. Immun. 78:1864-1873.
    • (2010) Infect. Immun. , vol.78 , pp. 1864-1873
    • Huang, B.1
  • 24
    • 33947410383 scopus 로고    scopus 로고
    • Porin activity of Anaplasma phagocytophilum outer membrane fraction and purified P44
    • Huang, H., X. Wang, T. Kikuchi, Y. Kumagai, and Y. Rikihisa. 2007. Porin activity of Anaplasma phagocytophilum outer membrane fraction and purified P44. J. Bacteriol. 189:1998-2006.
    • (2007) J. Bacteriol. , vol.189 , pp. 1998-2006
    • Huang, H.1    Wang, X.2    Kikuchi, T.3    Kumagai, Y.4    Rikihisa, Y.5
  • 25
    • 4544382411 scopus 로고    scopus 로고
    • Neutrophil NADPH oxidase is reduced at the Anaplasma phagocytophilum phagosome
    • IJdo, J. W., and A. C. Mueller. 2004. Neutrophil NADPH oxidase is reduced at the Anaplasma phagocytophilum phagosome. Infect. Immun. 72:5392-5401.
    • (2004) Infect. Immun. , vol.72 , pp. 5392-5401
    • Ijdo, J.W.1    Mueller, A.C.2
  • 26
    • 0032836127 scopus 로고    scopus 로고
    • Serodiagnosis of human granulocytic ehrlichiosis by a recombinant HGE-44-based enzymelinked immunosorbent assay
    • IJdo, J. W., C. Wu, L. A. Magnarelli, and E. Fikrig. 1999. Serodiagnosis of human granulocytic ehrlichiosis by a recombinant HGE-44-based enzymelinked immunosorbent assay. J. Clin. Microbiol. 37:3540-3544.
    • (1999) J. Clin. Microbiol. , vol.37 , pp. 3540-3544
    • Ijdo, J.W.1    Wu, C.2    Magnarelli, L.A.3    Fikrig, E.4
  • 27
    • 0036719903 scopus 로고    scopus 로고
    • Differential expression of the p44 gene family in the agent of human granulocytic ehrlichiosis
    • IJdo, J. W., C. Wu, S. R. Telford, III, and E. Fikrig. 2002. Differential expression of the p44 gene family in the agent of human granulocytic ehrlichiosis. Infect. Immun. 70:5295-5298.
    • (2002) Infect. Immun. , vol.70 , pp. 5295-5298
    • Ijdo, J.W.1    Wu, C.2    Telford III, S.R.3    Fikrig, E.4
  • 28
    • 0035577035 scopus 로고    scopus 로고
    • Host cell-specific expression of a p44 epitope by the human granulocytic ehrlichiosis agent
    • Jauron, S. D., et al. 2001. Host cell-specific expression of a p44 epitope by the human granulocytic ehrlichiosis agent. J. Infect. Dis. 184:1445-1450.
    • (2001) J. Infect. Dis. , vol.184 , pp. 1445-1450
    • Jauron, S.D.1
  • 29
    • 33748045474 scopus 로고    scopus 로고
    • Biochemical activities of three pairs of Ehrlichia chaffeensis two-component regulatory system proteins involved in inhibition of lysosomal fusion
    • Kumagai, Y., Z. Cheng, M. Lin, and Y. Rikihisa. 2006. Biochemical activities of three pairs of Ehrlichia chaffeensis two-component regulatory system proteins involved in inhibition of lysosomal fusion. Infect. Immun. 74:5014-5022.
    • (2006) Infect. Immun. , vol.74 , pp. 5014-5022
    • Kumagai, Y.1    Cheng, Z.2    Lin, M.3    Rikihisa, Y.4
  • 30
    • 63449138218 scopus 로고    scopus 로고
    • The Anaplasma phagocytophilum PleC histidine kinase and PleD diguanylate cyclase two-component system and role of cyclic di-GMP in host cell infection
    • Lai, T. H., Y. Kumagai, M. Hyodo, Y. Hayakawa, and Y. Rikihisa. 2009. The Anaplasma phagocytophilum PleC histidine kinase and PleD diguanylate cyclase two-component system and role of cyclic di-GMP in host cell infection. J. Bacteriol. 191:693-700.
    • (2009) J. Bacteriol. , vol.191 , pp. 693-700
    • Lai, T.H.1    Kumagai, Y.2    Hyodo, M.3    Hayakawa, Y.4    Rikihisa, Y.5
  • 31
    • 63049138916 scopus 로고    scopus 로고
    • Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures
    • Li, G. Z., et al. 2009. Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures. Proteomics 9:1696-1719.
    • (2009) Proteomics , vol.9 , pp. 1696-1719
    • Li, G.Z.1
  • 32
    • 79960140462 scopus 로고    scopus 로고
    • Gloabal proteomic analysis of two tick-borne emerging zoonotic agents: Anaplasma phagocytophilum and Ehrlichis chaffeensis
    • article 24. doi:103389/fmicb.2011.00024
    • Lin, M., T. Kikuchi, H. M. Brewer, A. D. Norbeck, and Y. Rikihisa. 2011. Gloabal proteomic analysis of two tick-borne emerging zoonotic agents: Anaplasma phagocytophilum and Ehrlichis chaffeensis. Front Microbiol. 2:article 24. doi:10.3389/fmicb.2011.00024.
    • (2011) Front Microbiol , vol.2
    • Lin, M.1    Kikuchi, T.2    Brewer, H.M.3    Norbeck, A.D.4    Rikihisa, Y.5
  • 33
    • 23444434654 scopus 로고    scopus 로고
    • Establishment of cloned Anaplasma phagocytophilum and analysis of p44 gene conversion within an infected horse and infected SCID mice
    • Lin, Q., and Y. Rikihisa. 2005. Establishment of cloned Anaplasma phagocytophilum and analysis of p44 gene conversion within an infected horse and infected SCID mice. Infect. Immun. 73:5106-5114.
    • (2005) Infect. Immun. , vol.73 , pp. 5106-5114
    • Lin, Q.1    Rikihisa, Y.2
  • 34
    • 0036702309 scopus 로고    scopus 로고
    • Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients
    • Lin, Q., et al. 2002. Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients. J. Clin. Microbiol. 40:2981-2988.
    • (2002) J. Clin. Microbiol. , vol.40 , pp. 2981-2988
    • Lin, Q.1
  • 36
    • 0036841212 scopus 로고    scopus 로고
    • Expression of Anaplasma marginale major surface protein 2 operon-associated proteins during mammalian and arthropod infection
    • Lohr, C. V., et al. 2002. Expression of Anaplasma marginale major surface protein 2 operon-associated proteins during mammalian and arthropod infection. Infect. Immun. 70:6005-6012.
    • (2002) Infect. Immun. , vol.70 , pp. 6005-6012
    • Lohr, C.V.1
  • 37
    • 0032812655 scopus 로고    scopus 로고
    • Invasion and intracellular development of the human granulocytic ehrlichiosis agent in tick cell culture
    • Munderloh, U. G., et al. 1999. Invasion and intracellular development of the human granulocytic ehrlichiosis agent in tick cell culture. J. Clin. Microbiol. 37:2518-2524.
    • (1999) J. Clin. Microbiol. , vol.37 , pp. 2518-2524
    • Munderloh, U.G.1
  • 38
    • 2942654840 scopus 로고    scopus 로고
    • Infection of endothelial cells with Anaplasma marginale and A. phagocytophilum
    • Munderloh, U. G., et al. 2004. Infection of endothelial cells with Anaplasma marginale and A. phagocytophilum. Vet. Microbiol. 101:53-64.
    • (2004) Vet. Microbiol. , vol.101 , pp. 53-64
    • Munderloh, U.G.1
  • 39
    • 0030023811 scopus 로고    scopus 로고
    • Isolation of the equine granulocytic ehrlichiosis agent, Ehrlichia equi, in tick cell culture
    • Munderloh, U. G., et al. 1996. Isolation of the equine granulocytic ehrlichiosis agent, Ehrlichia equi, in tick cell culture. J. Clin. Microbiol. 34:664-670.
    • (1996) J. Clin. Microbiol. , vol.34 , pp. 664-670
    • Munderloh, U.G.1
  • 40
    • 50849100137 scopus 로고    scopus 로고
    • Whole genome transcription profiling of Anaplasma phagocytophilum in human and tick host cells by tiling array analysis
    • Nelson, C. M., et al. 2008. Whole genome transcription profiling of Anaplasma phagocytophilum in human and tick host cells by tiling array analysis. BMC Genomics 9:364.
    • (2008) BMC Genomics , vol.9 , pp. 364
    • Nelson, C.M.1
  • 41
    • 77649251212 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction
    • Niu, H., V. Kozjak-Pavlovic, T. Rudel, and Y. Rikihisa. 2010. Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction. PLoS Pathog. 6:e1000774.
    • (2010) PLoS Pathog , vol.6
    • Niu, H.1    Kozjak-Pavlovic, V.2    Rudel, T.3    Rikihisa, Y.4
  • 42
    • 72749109443 scopus 로고    scopus 로고
    • 'Nothing is permanent but change'-antigenic variation in persistent bacterial pathogens
    • Palmer, G. H., T. Bankhead, and S. A. Lukehart. 2009. 'Nothing is permanent but change'-antigenic variation in persistent bacterial pathogens. Cell. Microbiol. 11:1697-1705.
    • (2009) Cell. Microbiol. , vol.11 , pp. 1697-1705
    • Palmer, G.H.1    Bankhead, T.2    Lukehart, S.A.3
  • 43
    • 0037972480 scopus 로고    scopus 로고
    • Major surface protein 2 of Anaplasma phagocytophilum facilitates adherence to granulocytes
    • Park, J., K. S. Choi, and J. S. Dumler. 2003. Major surface protein 2 of Anaplasma phagocytophilum facilitates adherence to granulocytes. Infect. Immun. 71:4018-4025.
    • (2003) Infect. Immun. , vol.71 , pp. 4018-4025
    • Park, J.1    Choi, K.S.2    Dumler, J.S.3
  • 44
    • 0031935981 scopus 로고    scopus 로고
    • Ultrastructural differentiation of the genogroups in the genus Ehrlichia
    • Popov, V. L., et al. 1998. Ultrastructural differentiation of the genogroups in the genus Ehrlichia. J. Med. Microbiol. 47:235-251.
    • (1998) J. Med. Microbiol. , vol.47 , pp. 235-251
    • Popov, V.L.1
  • 45
    • 77951097433 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells
    • Rikihisa, Y. 2010. Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells. Nat. Rev. Microbiol. 8:328-339.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 328-339
    • Rikihisa, Y.1
  • 46
    • 0031015273 scopus 로고    scopus 로고
    • Ultrastructural and antigenic characterization of a granulocytic ehrlichiosis agent directly isolated and stably cultivated from a patient in New York state
    • Rikihisa, Y., et al. 1997. Ultrastructural and antigenic characterization of a granulocytic ehrlichiosis agent directly isolated and stably cultivated from a patient in New York state. J. Infect. Dis. 175:210-213.
    • (1997) J. Infect. Dis. , vol.175 , pp. 210-213
    • Rikihisa, Y.1
  • 47
    • 2942596226 scopus 로고    scopus 로고
    • Restricted changes in major surface protein-2 (msp2) transcription after prolonged in vitro passage of Anaplasma phagocytophilum
    • Scorpio, D. G., K. Caspersen, H. Ogata, J. Park, and J. S. Dumler. 2004. Restricted changes in major surface protein-2 (msp2) transcription after prolonged in vitro passage of Anaplasma phagocytophilum. BMC Microbiol. 4:1.
    • (2004) BMC Microbiol , vol.4 , pp. 1
    • Scorpio, D.G.1    Caspersen, K.2    Ogata, H.3    Park, J.4    Dumler, J.S.5
  • 48
    • 0036149933 scopus 로고    scopus 로고
    • Expression of major surface protein 2 variants with conserved T-cell epitopes in Anaplasma centrale vaccinates
    • Shkap, V., T. Molad, K. A. Brayton, W. C. Brown, and G. H. Palmer. 2002. Expression of major surface protein 2 variants with conserved T-cell epitopes in Anaplasma centrale vaccinates. Infect. Immun. 70:642-648.
    • (2002) Infect. Immun. , vol.70 , pp. 642-648
    • Shkap, V.1    Molad, T.2    Brayton, K.A.3    Brown, W.C.4    Palmer, G.H.5
  • 49
    • 11044231152 scopus 로고    scopus 로고
    • Ehrlichia chaffeensis expresses macrophage- and tick cell-specific 28-kilodalton outer membrane proteins
    • Singu, V., H. Liu, C. Cheng, and R. R. Ganta. 2005. Ehrlichia chaffeensis expresses macrophage- and tick cell-specific 28-kilodalton outer membrane proteins. Infect. Immun. 73:79-87.
    • (2005) Infect. Immun. , vol.73 , pp. 79-87
    • Singu, V.1    Liu, H.2    Cheng, C.3    Ganta, R.R.4
  • 50
    • 33747009964 scopus 로고    scopus 로고
    • Unique macrophage and tick cell-specific protein expression from the p28/p30-outer membrane protein multigene locus in Ehrlichia chaffeensis and Ehrlichia canis
    • Singu, V., et al. 2006. Unique macrophage and tick cell-specific protein expression from the p28/p30-outer membrane protein multigene locus in Ehrlichia chaffeensis and Ehrlichia canis. Cell. Microbiol. 8:1475-1487.
    • (2006) Cell. Microbiol. , vol.8 , pp. 1475-1487
    • Singu, V.1
  • 52
    • 78650256980 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum AptA modulates Erk1/2 signalling
    • Sukumaran, B., et al. 2011. Anaplasma phagocytophilum AptA modulates Erk1/2 signalling. Cell. Microbiol. 13:47-61.
    • (2011) Cell. Microbiol. , vol.13 , pp. 47-61
    • Sukumaran, B.1
  • 53
    • 77449143169 scopus 로고    scopus 로고
    • Purifying natively folded proteins from inclusion bodies using sarkosyl, Triton X-100, and CHAPS
    • Tao, H., et al. 2010. Purifying natively folded proteins from inclusion bodies using sarkosyl, Triton X-100, and CHAPS. Biotechniques 48:61-64.
    • (2010) Biotechniques 48 , pp. 61-64
    • Tao, H.1
  • 54
    • 70350468702 scopus 로고    scopus 로고
    • Current management of human granulocytic anaplasmosis, human monocytic ehrlichiosis and Ehrlichia ewingii ehrlichiosis
    • Thomas, R. J., J. S. Dumler, and J. A. Carlyon. 2009. Current management of human granulocytic anaplasmosis, human monocytic ehrlichiosis and Ehrlichia ewingii ehrlichiosis. Expert Rev. Anti Infect. Ther. 7:709-722.
    • (2009) Expert Rev. Anti Infect. Ther. , vol.7 , pp. 709-722
    • Thomas, R.J.1    Dumler, J.S.2    Carlyon, J.A.3
  • 55
    • 0027968068 scopus 로고
    • CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J. D., D. G. Higgins, and T. J. Gibson. 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:4673-4680.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 56
    • 69049095022 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum densecored organisms mediate cellular adherence through recognition of human P-selectin glycoprotein ligand 1
    • Troese, M. J., and J. A. Carlyon. 2009. Anaplasma phagocytophilum densecored organisms mediate cellular adherence through recognition of human P-selectin glycoprotein ligand 1. Infect. Immun. 77:4018-4027.
    • (2009) Infect. Immun. , vol.77 , pp. 4018-4027
    • Troese, M.J.1    Carlyon, J.A.2
  • 57
    • 65449156907 scopus 로고    scopus 로고
    • Differential expression and glycosylation of Anaplasma phagocytophilum major surface protein 2 paralogs during cultivation in sialyl Lewis x-deficient host cells
    • Troese, M. J., et al. 2009. Differential expression and glycosylation of Anaplasma phagocytophilum major surface protein 2 paralogs during cultivation in sialyl Lewis x-deficient host cells. Infect. Immun. 77:1746-1756.
    • (2009) Infect. Immun. , vol.77 , pp. 1746-1756
    • Troese, M.J.1
  • 59
    • 0032080403 scopus 로고    scopus 로고
    • The agent of Human Granulocytic Ehrlichiosis resides in an endosomal compartment
    • Webster, P., J. W. IJdo, L. M. Chicoine, and E. Fikrig. 1998. The agent of Human Granulocytic Ehrlichiosis resides in an endosomal compartment. J. Clin. Invest. 101:1932-1941.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1932-1941
    • Webster, P.1    Ijdo, J.W.2    Chicoine, L.M.3    Fikrig, E.4
  • 61
    • 0033580934 scopus 로고    scopus 로고
    • Multiple p44 genes encoding major outer membrane proteins are expressed in the human granulocytic ehrlichiosis agent
    • Zhi, N., N. Ohashi, and Y. Rikihisa. 1999. Multiple p44 genes encoding major outer membrane proteins are expressed in the human granulocytic ehrlichiosis agent. J. Biol. Chem. 274:17828-17836.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17828-17836
    • Zhi, N.1    Ohashi, N.2    Rikihisa, Y.3
  • 62
    • 0036175313 scopus 로고    scopus 로고
    • Transcript heterogeneity of the p44 multigene family in a human granulocytic ehrlichiosis agent transmitted by ticks
    • Zhi, N., et al. 2002. Transcript heterogeneity of the p44 multigene family in a human granulocytic ehrlichiosis agent transmitted by ticks. Infect. Immun. 70:1175-1184.
    • (2002) Infect. Immun. , vol.70 , pp. 1175-1184
    • Zhi, N.1


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