Sustained and localized in vitro release of BMP-2/7, RANKL, and tetracycline from FlexBone, an elastomeric osteoconductive bone substitute

Journal of Orthopaedic Research

Volumn 27, Issue 10, 2009, Pages 1306-1311

  Xu, Jianwen ^a   Li, Xinning ^a   Lian, Jane B ^a   Ayers, David C ^a   Song, Jie ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Bone morphogenetic protein; Hydrogel; Hydroxyapatite; Receptor activator of nuclear factor B ligand; Tetracycline

Indexed keywords

CALCIUM PHOSPHATE; ELASTOMER; HYDROXYAPATITE; NANOCRYSTAL; OSTEOCLAST DIFFERENTIATION FACTOR; POLYMACON; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT OSTEOGENIC PROTEIN 1; TETRACYCLINE;

ADSORPTION; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIUM CULTURE; BONE DEFECT; BONE PROSTHESIS; BONE REMODELING; CELL DIFFERENTIATION; CHEMICAL ENVIRONMENT; CONTROLLED STUDY; CROSS LINKING; DRUG RELEASE; ENCAPSULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; HYDROGEL; LOADING TEST; MACROPHAGE; MOUSE; MYOBLAST; NONHUMAN; OSSIFICATION; POLYMERIZATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 7; BONE SUBSTITUTES; CELL DIFFERENTIATION; CELL LINE; HUMANS; MACROPHAGES; MICE; MYOBLASTS, SKELETAL; OSTEOCLASTS; OSTEOGENESIS; RANK LIGAND; RECOMBINANT PROTEINS; TETRACYCLINE;

EID: 70349214840     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20890     Document Type: Article

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