-
1
-
-
0035856952
-
Beta-cell death during progression to diabetes
-
Mathis D, Vence L, Benoist C. Beta-cell death during progression to diabetes. Nature 2001; 414(6865): 792-798.
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 792-798
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
2
-
-
0035668779
-
A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis
-
Eizirik DL, Mandrup-Poulsen T. A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 2001; 44(12): 2115-2133.
-
(2001)
Diabetologia
, vol.44
, Issue.12
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
3
-
-
4744355191
-
Death effectors of beta-cell apoptosis in type 1 diabetes
-
Lee MS, Chang I, Kim S. Death effectors of beta-cell apoptosis in type 1 diabetes. Mol Genet Metab 2004; 83(1-2): 82-92.
-
(2004)
Mol Genet Metab
, vol.83
, Issue.1-2
, pp. 82-92
-
-
Lee, M.S.1
Chang, I.2
Kim, S.3
-
4
-
-
0345448056
-
Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model
-
Turley S, Poirot L, Hattori M, Benoist C, Mathis D. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J Exp Med 2003; 198: 1527-1537.
-
(2003)
J Exp Med
, vol.198
, pp. 1527-1537
-
-
Turley, S.1
Poirot, L.2
Hattori, M.3
Benoist, C.4
Mathis, D.5
-
5
-
-
34548036686
-
Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes
-
Kim HS, Han MS, Chung KW, et al. Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes. Immunity 2007; 27(2): 321-333.
-
(2007)
Immunity
, vol.27
, Issue.2
, pp. 321-333
-
-
Kim, H.S.1
Han, M.S.2
Chung, K.W.3
-
6
-
-
0036884424
-
A blast from the past: clearance of apoptotic cells regulates immune responses
-
Savill J, Dransfield I, Gregory C, Haslett C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol 2002; 2: 965-975.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 965-975
-
-
Savill, J.1
Dransfield, I.2
Gregory, C.3
Haslett, C.4
-
7
-
-
0032695108
-
Natural adjuvants: endogenous activators of dentritic cells
-
Gallucchi S, Lolkema M, Matzinger P. Natural adjuvants: endogenous activators of dentritic cells. Nat Med 1999; 5: 1249-1255.
-
(1999)
Nat Med
, vol.5
, pp. 1249-1255
-
-
Gallucchi, S.1
Lolkema, M.2
Matzinger, P.3
-
8
-
-
0035877013
-
An essential role of the NF-kappa B/toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells
-
Li M, Carpio DF, Zheng Y, et al. An essential role of the NF-kappa B/toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. J Immunol 2001; 166: 7128-7135.
-
(2001)
J Immunol
, vol.166
, pp. 7128-7135
-
-
Li, M.1
Carpio, D.F.2
Zheng, Y.3
-
9
-
-
0035338504
-
Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteases
-
Fadok VA, Bratton DL, Guthrie L, Henson PM. Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteases. J Immunol 2001; 166: 6847-6854.
-
(2001)
J Immunol
, vol.166
, pp. 6847-6854
-
-
Fadok, V.A.1
Bratton, D.L.2
Guthrie, L.3
Henson, P.M.4
-
10
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002; 418: 191-195.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
11
-
-
0031825552
-
Systemic exposure to irradiated apoptotic cells induces autoantibody production
-
Mevorach D, Zhou JL, Song X, Elkon KB. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J Exp Med 1998; 188: 387-392.
-
(1998)
J Exp Med
, vol.188
, pp. 387-392
-
-
Mevorach, D.1
Zhou, J.L.2
Song, X.3
Elkon, K.B.4
-
12
-
-
2442665179
-
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice
-
Hanayama R, Tanaka M, Miyasaka K, et al. Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science 2004; 304: 1147-1150.
-
(2004)
Science
, vol.304
, pp. 1147-1150
-
-
Hanayama, R.1
Tanaka, M.2
Miyasaka, K.3
-
13
-
-
0035837323
-
Phagocytosis and clearance of apoptotic cells is mediated by MER
-
Scott RS, McMahon EJ, Pop SM, et al. Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 2001; 411: 207-211.
-
(2001)
Nature
, vol.411
, pp. 207-211
-
-
Scott, R.S.1
McMahon, E.J.2
Pop, S.M.3
-
14
-
-
0025908652
-
Streptozotocin- and alloxan-induced H2O2 generation and DNA fragmentation in pancreatic islets
-
Takasu N, Komiya I, Asawa T, Nagasawa Y, Yamada T. Streptozotocin- and alloxan-induced H2O2 generation and DNA fragmentation in pancreatic islets. Diabetes 1991; 40: 1141-1145.
-
(1991)
Diabetes
, vol.40
, pp. 1141-1145
-
-
Takasu, N.1
Komiya, I.2
Asawa, T.3
Nagasawa, Y.4
Yamada, T.5
-
15
-
-
0033770540
-
Life and death of the pancreatic b-cells
-
Bonner-Weir S. Life and death of the pancreatic b-cells. Trends Endocrinol Metab 2000; 9: 375-378.
-
(2000)
Trends Endocrinol Metab
, vol.9
, pp. 375-378
-
-
Bonner-Weir, S.1
-
16
-
-
0036320896
-
Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced
-
O'Brien BA, Huang Y, Geng X, Dutz JP, Finegood DT. Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced. Diabetes 2002; 2002: 2481-2488.
-
(2002)
Diabetes
, vol.2002
, pp. 2481-2488
-
-
O'Brien, B.A.1
Huang, Y.2
Geng, X.3
Dutz, J.P.4
Finegood, D.T.5
-
17
-
-
0033985277
-
Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?
-
Trudeau JD, Dutz JP, Arany E, Hill DJ, Fieldus WE, Finegood DT. Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes? Diabetes 2000; 49: 1-7.
-
(2000)
Diabetes
, vol.49
, pp. 1-7
-
-
Trudeau, J.D.1
Dutz, J.P.2
Arany, E.3
Hill, D.J.4
Fieldus, W.E.5
Finegood, D.T.6
-
18
-
-
0036141519
-
Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes
-
Horwitz MS, Ilic A, Fine C, Rodriguez E, Sarvetnick N. Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes. J Clin Invest 2002; 109: 79-87.
-
(2002)
J Clin Invest
, vol.109
, pp. 79-87
-
-
Horwitz, M.S.1
Ilic, A.2
Fine, C.3
Rodriguez, E.4
Sarvetnick, N.5
-
19
-
-
79955157031
-
TLR2 signaling improves immunoregulation to prevent type 1 diabetes
-
Filippi CM, Ehrhardt K, Estes EA, Larsson P, Oldham JE, von Herrath MG. TLR2 signaling improves immunoregulation to prevent type 1 diabetes. Eur J Immunol 2011; 41(5): 1399-1409.
-
(2011)
Eur J Immunol
, vol.41
, Issue.5
, pp. 1399-1409
-
-
Filippi, C.M.1
Ehrhardt, K.2
Estes, E.A.3
Larsson, P.4
Oldham, J.E.5
von Herrath, M.G.6
-
20
-
-
16844365788
-
Naturally arising Foxp3-expressing CD25 + CD4+ regulatory T cells in immunological tolerance to self and non-self
-
Sakaguchi S. Naturally arising Foxp3-expressing CD25 + CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005; 6(4): 345-352.
-
(2005)
Nat Immunol
, vol.6
, Issue.4
, pp. 345-352
-
-
Sakaguchi, S.1
-
21
-
-
0037450804
-
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
-
Caramalho I, Lopes-Carvalho T, Ostler D, Zelenay S, Haury M, Demengeot J. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med 2003; 197(4): 403-411.
-
(2003)
J Exp Med
, vol.197
, Issue.4
, pp. 403-411
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
Zelenay, S.4
Haury, M.5
Demengeot, J.6
-
22
-
-
32444432610
-
Toll-like receptor 2 controls expansion and function of regulatory T cells
-
Sutmuller RP, den Brok MH, Kramer M, et al. Toll-like receptor 2 controls expansion and function of regulatory T cells. J Clin Invest 2006; 116(2): 485-494.
-
(2006)
J Clin Invest
, vol.116
, Issue.2
, pp. 485-494
-
-
Sutmuller, R.P.1
den Brok, M.H.2
Kramer, M.3
-
23
-
-
0030960632
-
Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens
-
Elias D, Meilin A, Ablamunits V, et al. Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens. Diabetes 1997; 46(5): 758-764.
-
(1997)
Diabetes
, vol.46
, Issue.5
, pp. 758-764
-
-
Elias, D.1
Meilin, A.2
Ablamunits, V.3
-
24
-
-
0035944844
-
Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial
-
Raz I, Elias D, Avron A, Tamir M, Metzger M, Cohen IR. Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. Lancet 2001; 358(9295): 1749-1753.
-
(2001)
Lancet
, vol.358
, Issue.9295
, pp. 1749-1753
-
-
Raz, I.1
Elias, D.2
Avron, A.3
Tamir, M.4
Metzger, M.5
Cohen, I.R.6
-
25
-
-
33745817772
-
Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling
-
Zanin-Zhorov A, Cahalon L, Tal G, Margalit R, Lider O, Cohen IR. Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling. J Clin Invest 2006; 116(7): 2022-2032.
-
(2006)
J Clin Invest
, vol.116
, Issue.7
, pp. 2022-2032
-
-
Zanin-Zhorov, A.1
Cahalon, L.2
Tal, G.3
Margalit, R.4
Lider, O.5
Cohen, I.R.6
-
26
-
-
54549122338
-
Innate immunity and intestinal microbiota in the development of type 1 diabetes
-
Wen L, Ley RE, Volchkov PY, et al. Innate immunity and intestinal microbiota in the development of type 1 diabetes. Nature 2008; 455(7216): 1109-1113.
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1109-1113
-
-
Wen, L.1
Ley, R.E.2
Volchkov, P.Y.3
-
27
-
-
77954735211
-
TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes
-
Zhang Y, Lee AS, Shameli A, et al. TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes. J Immunol 2010; 184(10): 5645-5653.
-
(2010)
J Immunol
, vol.184
, Issue.10
, pp. 5645-5653
-
-
Zhang, Y.1
Lee, A.S.2
Shameli, A.3
-
28
-
-
34247891509
-
Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease
-
Marshak-Rothstein A, Rifkin IR. Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Ann Rev Immunol 2007; 25: 419-441.
-
(2007)
Ann Rev Immunol
, vol.25
, pp. 419-441
-
-
Marshak-Rothstein, A.1
Rifkin, I.R.2
-
29
-
-
0034886143
-
Toll-like receptors: critical proteins linking innate and acquired immunity
-
Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001; 2(8): 675-680.
-
(2001)
Nat Immunol
, vol.2
, Issue.8
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
30
-
-
28444494764
-
Infections and autoimmune diseases
-
Bach JF. Infections and autoimmune diseases. J Autoimmun 2005; 25(Suppl.): 74-80.
-
(2005)
J Autoimmun
, vol.25
, Issue.SUPPL.
, pp. 74-80
-
-
Bach, J.F.1
|