Suppression of microsomal cytochrome P450-dependent monooxygenases and mitochondrial oxidative phosphorylation by fullerenol, a polyhydroxylated fullerene C60

Toxicology Letters

Volumn 93, Issue 1, 1997, Pages 29-37

  Ueng, Tzuu Huei ^a   Kang, Jaw Jou ^a   Wang, Hui Wu ^a   Cheng, Yu Wen ^a   Chiang, Long Y ^b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Fullerene; Mitochondrial dysfunction; P450 suppression

Indexed keywords

7 ETHOXYCOUMARIN DEETHYLASE; CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; FULLERENE DERIVATIVE; UNSPECIFIC MONOOXYGENASE;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENZYME INHIBITION; LD 50; LIVER MICROSOME; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT;

ANIMALS; CA(2+) MG(2+)-ATPASE; CARBON; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; FULLERENES; LETHAL DOSE 50; MALE; MICE; MICE, INBRED ICR; MICROSOMES, LIVER; MITOCHONDRIA, LIVER; OXIDATIVE PHOSPHORYLATION; RATS;

ANIMALIA;

EID: 0031578443     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(97)00071-4     Document Type: Article

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