Type 2 diabetes risk variants and colorectal cancer risk: The Multiethnic Cohort and PAGE studies

Gut

Volumn 60, Issue 12, 2011, Pages 1703-1711

  Cheng, Iona ^a   Caberto, Christian P ^a   Lum Jones, Annette ^a   Seifried, Ann ^a   Wilkens, Lynne R ^a   Schumacher, Fredrick R ^b   Monroe, Kristine R ^b   Lim, Unhee ^a   Tiirikainen, Maarit ^a   Kolonel, Laurence N ^a   Henderson, Brian E ^b   Stram, Daniel O ^b   Haiman, Christopher A ^b   Marchand, Loïc Le ^a  

^a UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE; AGED; ALLELE; ARTICLE; BODY MASS; CANCER PATIENT; CANCER RISK; CASE CONTROL STUDY; COHORT ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; DNA POLYMORPHISM; ETHNICITY; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POPULATION ARCHITECTURE USING GENOMICS AND EPIDEMIOLOGY STUDY; PRIORITY JOURNAL; SEX; SINGLE NUCLEOTIDE POLYMORPHISM; TYPES OF STUDY;

AGED; BODY MASS INDEX; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; CONTINENTAL POPULATION GROUPS; DIABETES MELLITUS, TYPE 2; ETHNIC GROUPS; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LOGISTIC MODELS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 80655144438     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2011.237727     Document Type: Article

References (51)

1. American Cancer Society. Cancer Facts & Figures 2010. Atlanta: American Cancer Society, 2010.
2. Mainous AG 3rd, Baker R, Koopman RJ, et al. Impact of the population at risk of diabetes on projections of diabetes burden in the United States: an epidemic on the way. Diabetologia 2007;50:934-40. (Pubitemid 46559242)
3. Larsson SC, Orsini N, Wolk A. Diabetes mellitus and risk of colorectal cancer: a meta-analysis. J Natl Cancer Inst 2005;97:1679-87. (Pubitemid 41672234)
4. He J, Stram DO, Kolonel LN, et al. The association of diabetes with colorectal cancer risk: the Multiethnic Cohort. Br J Cancer 2010;103:120-6.
5. Giovannucci E, Harlan DM, Archer MC, et al. Diabetes and cancer: a consensus report. CA Cancer J Clin 2010;60:207-21.
6. Will JC, Galuska D, Vinicor F, et al. Colorectal cancer: another complication of diabetes mellitus? Am J Epidemiol 1998;147:816-25. (Pubitemid 28244386)
7. Nilsen TI, Vatten LJ. Prospective study of colorectal cancer risk and physical activity, diabetes, blood glucose and BMI: exploring the hyperinsulinaemia hypothesis. Br J Cancer 2001;84:417-22. (Pubitemid 32154439)
8. Seow A, Yuan JM, Koh WP, et al. Diabetes mellitus and risk of colorectal cancer in the Singapore Chinese Health Study. J Natl Cancer Inst 2006;98:135-8. (Pubitemid 43159968)
9. Vinikoor LC, Long MD, Keku TO, et al. The association between diabetes, insulin use, and colorectal cancer among Whites and African Americans. Cancer Epidemiol Biomarkers Prev 2009;18:1239-42.
10. Folsom AR, Pankow JS, Peacock JM, et al. Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care 2008;31:905-9.
11. Hazra A, Fuchs CS, Chan AT, et al. Association of the TCF7L2 polymorphism with colorectal cancer and adenoma risk. Cancer Causes Control 2008;19:975-80.
12. Slattery ML, Folsom AR, Wolff R, et al. Transcription factor 7-like 2 polymorphism and colon cancer. Cancer Epidemiol Biomarkers Prev 2008;17:978-82.
13. Rung J, Cauchi S, Albrechtsen A, et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet 2009; 41:1110-15.
14. Saxena R, Voight BF, Lyssenko V, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007;316:1331-6. (Pubitemid 46871653)
15. Scott LJ, Mohlke KL, Bonnycastle LL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007;316:1341-5. (Pubitemid 46871655)
16. Sladek R, Rocheleau G, Rung J, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007;445:881-5.
17. Steinthorsdottir V, Thorleifsson G, Reynisdottir I, et al. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 2007;39:770-5. (Pubitemid 46848592)
18. Takeuchi F, Serizawa M, Yamamoto K, et al. Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes 2009;58:1690-9.
19. Timpson NJ, Lindgren CM, Weedon MN, et al. Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. Diabetes 2009;58:505-10.
20. Zeggini E, Scott LJ, Saxena R, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008;40:638-45. (Pubitemid 351601209)
21. Pechlivanis S, Pardini B, Bermejo JL, et al. Insulin pathway related genes and risk of colorectal cancer: INSR promoter polymorphism shows a protective effect. Endocr Relat Cancer 2007;14:733-40. (Pubitemid 350074062)
22. Landi D, Moreno V, Guino E, et al. Polymorphisms affecting micro-RNA regulation and associated with the risk of dietary-related cancers: a review from the literature and new evidence for a functional role of rs17281995 (CD86) and rs1051690 (INSR), previously associated with colorectal cancer. Mutat Res. Published Online First: 30 October 2010. doi:10.1016/j.mrfmmm.2010.10.002.
23. Leroy EC, Moore JH, Hu C, et al. Genes in the insulin and insulin-like growth factor pathway and odds of metachronous colorectal neoplasia. Hum Genet 2011;129:503-12.
24. Salonen JT, Uimari P, Aalto JM, et al. Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. Am J Hum Genet 2007;81:338-45. (Pubitemid 47236080)
25. Unoki H, Takahashi A, Kawaguchi T, et al. SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 2008;40:1098-102.
26. Yasuda K, Miyake K, Horikawa Y, et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 2008;40:1092-7.
27. Zeggini E, Weedon MN, Lindgren CM, et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007;316:1336-41. (Pubitemid 46871654)
28. Pare G, Chasman DI, Parker AN, et al. Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study. PLoS Genet 2008;4:e1000312.
29. Sandhu MS, Weedon MN, Fawcett KA, et al. Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet 2007;39:951-3. (Pubitemid 47185173)
30. Kolonel LN, Henderson BE, Hankin JH, et al. A multiethnic cohort in Hawaii and Los Angeles: baseline characteristics. Am J Epidemiol 2000;151:346-57. (Pubitemid 30463612)
31. Gauderman WJ. Sample size requirements for association studies of gene - gene interaction. Am J Epidemiol 2002;155:478-84. (Pubitemid 34174160)
32. He J, Wilkens LR, Stram DO, et al. Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations. Cancer Epidemiol Biomarkers Prev 2011;20:70-81.
33. Tsai FJ, Yang CF, Chen CC, et al. A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. PLoS Genet 2010;6:e1000847.
34. Price AL, Patterson NJ, Plenge RM, et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006;38:904-9. (Pubitemid 44141658)
35. Kosoy R, Nassir R, Tian C, et al. Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America. Hum Mutat 2009;30:69-78.
36. Hirschhorn JN, Daly MJ. Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 2005;6:95-108. (Pubitemid 40179532)
37. Drieschner N, Belge G, Rippe V, et al. Evidence for a 3p25 breakpoint hot spot region in thyroid tumors of follicular origin. Thyroid 2006;16:1091-6. (Pubitemid 44864483)
38. Rippe V, Drieschner N, Meiboom M, et al. Identification of a gene rearranged by 2p21 aberrations in thyroid adenomas. Oncogene 2003;22:6111-14. (Pubitemid 37175890)
39. Eeles RA, Kote-Jarai Z, Al Olama AA, et al. Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet 2009;41:1116-21.
40. Hu C, Zhang R, Wang C, et al. PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population. PLoS One 2009;4:e7643.
41. Cook DL, Hales CN. Intracellular ATP directly blocks K+ channels in pancreatic B-cells. Nature 1984;311:271-3. (Pubitemid 14071146)
42. Inagaki N, Gonoi T, Clement JP 4th, et al. Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 1995;270:1166-70.
43. Stancakova A, Kuulasmaa T, Paananen J, et al. Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men. Diabetes 2009;58:2129-36.
44. Koontz JI, Soreng AL, Nucci M, et al. Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors. Proc Natl Acad Sci USA 2001;98:6348-53. (Pubitemid 32488241)
45. Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci USA 2002;99:16899-903. (Pubitemid 36034070)
46. Voight BF, Scott LJ, Steinthorsdottir V, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010;42:579-89.
47. Thomas G, Jacobs KB, Yeager M, et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet 2008;40:310-15. (Pubitemid 351311773)
48. Johansson A, Marroni F, Hayward C, et al. Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Hum Mol Genet 2009;18:373-80.
49. Soranzo N, Rivadeneira F, Chinappen-Horsley U, et al. Meta-analysis of genome-wide scans for human adult stature identifies novel loci and associations with measures of skeletal frame size. PLoS Genet 2009;5:e1000445.
50. Szala S, Froehlich M, Scollon M, et al. Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2. Proc Natl Acad Sci USA 1990;87:3542-6.
51. Greco C, Bralet MP, Ailane N, et al. E-cadherin/p120-catenin and tetraspanin Co-029 cooperate for cell motility control in human colon carcinoma. Cancer Res 2010;70:7674-83.