-
1
-
-
0029893417
-
A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies
-
Almind K, Inoue G, Pedersen O & Kahn CR 1996 A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies. Journal of Clinical Investigation 97 2569-2575.
-
(1996)
Journal of Clinical Investigation
, vol.97
, pp. 2569-2575
-
-
Almind, K.1
Inoue, G.2
Pedersen, O.3
Kahn, C.R.4
-
2
-
-
0025827852
-
A cluster of four Sp1 binding sites required for efficient expression of the human insulin receptor gene
-
Araki E, Murakami T, Shirotani T, Kanai F, Shinohara Y, Shimada F, Mori M, Shichiri M & Ebina Y 1991 A cluster of four Sp1 binding sites required for efficient expression of the human insulin receptor gene. Journal of Biological Chemistry 266 3944-3948.
-
(1991)
Journal of Biological Chemistry
, vol.266
, pp. 3944-3948
-
-
Araki, E.1
Murakami, T.2
Shirotani, T.3
Kanai, F.4
Shinohara, Y.5
Shimada, F.6
Mori, M.7
Shichiri, M.8
Ebina, Y.9
-
3
-
-
0030444451
-
Human type 1 diabetes and the insulin gene: Principles of mapping polygenes
-
Bennett ST & Todd JA 1996 Human type 1 diabetes and the insulin gene: principles of mapping polygenes. Annual Review of Genetics 30 343-370.
-
(1996)
Annual Review of Genetics
, vol.30
, pp. 343-370
-
-
Bennett, S.T.1
Todd, J.A.2
-
4
-
-
33645982255
-
From mice to men: Insights into the insulin resistance syndromes
-
Biddinger SB & Kahn CR 2006 From mice to men: insights into the insulin resistance syndromes. Annual Review of Physiology 68 123-158.
-
(2006)
Annual Review of Physiology
, vol.68
, pp. 123-158
-
-
Biddinger, S.B.1
Kahn, C.R.2
-
5
-
-
3543072186
-
Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
-
Calle EE & Kaaks R 2004 Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nature Reviews. Cancer 4 579-591.
-
(2004)
Nature Reviews. Cancer
, vol.4
, pp. 579-591
-
-
Calle, E.E.1
Kaaks, R.2
-
6
-
-
4944240144
-
Genetic predisposition to colorectal cancer
-
de la Chapelle A 2004 Genetic predisposition to colorectal cancer. Nature Reviews. Cancer 4 769-780.
-
(2004)
Nature Reviews. Cancer
, vol.4
, pp. 769-780
-
-
de la Chapelle, A.1
-
7
-
-
33750527523
-
Haplotype-based association studies of IGFBPI and IGFBP3 with prostate and breast cancer risk: The multiethnic cohort
-
Cheng I, Penney KL, Stram DO, Le Marchand L, Giorgi E, Haiman CA, Kolonel LN, Pike M, Hirschhorn J, Henderson BE et al. 2006 Haplotype-based association studies of IGFBPI and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort. Cancer Epidemiology, Biomarkers and Prevention 15 1993-1997.
-
(2006)
Cancer Epidemiology, Biomarkers and Prevention
, vol.15
, pp. 1993-1997
-
-
Cheng, I.1
Penney, K.L.2
Stram, D.O.3
Le Marchand, L.4
Giorgi, E.5
Haiman, C.A.6
Kolonel, L.N.7
Pike, M.8
Hirschhorn, J.9
Henderson, B.E.10
-
8
-
-
24944432276
-
INSPstI polymorphism and prostate cancer in African-American men
-
Claeys GB, Sarma AV, Dunn RL, Zuhlke KA, Beebe-Dimmer J, Montie JE, Wojno KJ, Schottenfeld D & Cooney KA 2005 INSPstI polymorphism and prostate cancer in African-American men. Prostate 65 83-87.
-
(2005)
Prostate
, vol.65
, pp. 83-87
-
-
Claeys, G.B.1
Sarma, A.V.2
Dunn, R.L.3
Zuhlke, K.A.4
Beebe-Dimmer, J.5
Montie, J.E.6
Wojno, K.J.7
Schottenfeld, D.8
Cooney, K.A.9
-
9
-
-
0037385239
-
A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription
-
Foti D, Iuliano R, Chiefari E & Brunetti A 2003 A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription. Molecular and Cellular Biology 23 2720-2732.
-
(2003)
Molecular and Cellular Biology
, vol.23
, pp. 2720-2732
-
-
Foti, D.1
Iuliano, R.2
Chiefari, E.3
Brunetti, A.4
-
10
-
-
0035160628
-
Insulin, insulin-like growth factors and colon cancer: A review of the evidence
-
Giovannucci E 2001 Insulin, insulin-like growth factors and colon cancer: a review of the evidence. Journal of Nutrition 131 3109S-3120S.
-
(2001)
Journal of Nutrition
, vol.131
-
-
Giovannucci, E.1
-
11
-
-
34247499482
-
Insulin resistance-related genes and advanced left-sided colorectal adenoma
-
Gunter MJ, Hayes RB, Chatterjee N, Yeager M, Welch R, Schoen RE, Yakochi L, Schatzkin A & Peters U 2007 Insulin resistance-related genes and advanced left-sided colorectal adenoma. Cancer Epidemiology, Biomarkers and Prevention 16 703-708.
-
(2007)
Cancer Epidemiology, Biomarkers and Prevention
, vol.16
, pp. 703-708
-
-
Gunter, M.J.1
Hayes, R.B.2
Chatterjee, N.3
Yeager, M.4
Welch, R.5
Schoen, R.E.6
Yakochi, L.7
Schatzkin, A.8
Peters, U.9
-
12
-
-
0028926007
-
Amplification and analysis of promoter region of insulin receptor gene in a patient with leprechaunism associated with severe insulin resistance
-
Haruta T, Imamura T, Iwanishi M, Egawa K, Goji K & Kobayashi M 1995 Amplification and analysis of promoter region of insulin receptor gene in a patient with leprechaunism associated with severe insulin resistance. Metabolism 44 430-437.
-
(1995)
Metabolism
, vol.44
, pp. 430-437
-
-
Haruta, T.1
Imamura, T.2
Iwanishi, M.3
Egawa, K.4
Goji, K.5
Kobayashi, M.6
-
13
-
-
0037468138
-
Polymorphism of the insulin gene is associated with increased prostate cancer risk
-
Ho GY, Melman A, Liu SM, Li M, Yu H, Negassa A, Burk RD, Hsing AW, Ghavamian R & Chua SC Jr 2003 Polymorphism of the insulin gene is associated with increased prostate cancer risk. British Journal of Cancer 88 263-269.
-
(2003)
British Journal of Cancer
, vol.88
, pp. 263-269
-
-
Ho, G.Y.1
Melman, A.2
Liu, S.M.3
Li, M.4
Yu, H.5
Negassa, A.6
Burk, R.D.7
Hsing, A.W.8
Ghavamian, R.9
Chua Jr, S.C.10
-
14
-
-
0034605463
-
Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women
-
Kaaks R, Toniolo P, Akhmedkhanov A, Lukanova A, Biessy C, Dechaud H, Rinaldi S, Zeleniuch-Jacquotte A, Shore RE & Riboli E 2000 Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women. Journal of National Cancer Institute 92 1592-1600.
-
(2000)
Journal of National Cancer Institute
, vol.92
, pp. 1592-1600
-
-
Kaaks, R.1
Toniolo, P.2
Akhmedkhanov, A.3
Lukanova, A.4
Biessy, C.5
Dechaud, H.6
Rinaldi, S.7
Zeleniuch-Jacquotte, A.8
Shore, R.E.9
Riboli, E.10
-
16
-
-
0025330709
-
Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance
-
Kadowaki T, Kadowaki H, Rechler MM, Serrano-Rios M, Roth J, Gorden P & Taylor SI 1990 Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance. Journal of Clinical Investigation 86 254-264.
-
(1990)
Journal of Clinical Investigation
, vol.86
, pp. 254-264
-
-
Kadowaki, T.1
Kadowaki, H.2
Rechler, M.M.3
Serrano-Rios, M.4
Roth, J.5
Gorden, P.6
Taylor, S.I.7
-
17
-
-
0038398622
-
The insulin-like growth factor system and cancer
-
LeRoith D & Roberts CT Jr 2003 The insulin-like growth factor system and cancer. Cancer Letters 195 127-137.
-
(2003)
Cancer Letters
, vol.195
, pp. 127-137
-
-
LeRoith, D.1
Roberts Jr, C.T.2
-
18
-
-
26444543423
-
No association between genetic polymorphisms in insulin and insulin receptor substrate-1 and prostate cancer
-
Li L, Cicek MS, Casey G & Witte JS 2005 No association between genetic polymorphisms in insulin and insulin receptor substrate-1 and prostate cancer. Cancer Epidemiology, Biomarkers and Prevention 14 2462-2463.
-
(2005)
Cancer Epidemiology, Biomarkers and Prevention
, vol.14
, pp. 2462-2463
-
-
Li, L.1
Cicek, M.S.2
Casey, G.3
Witte, J.S.4
-
19
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer - analyses of cohorts of twins from Sweden, Denmark, and Finland
-
Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, Koskenvuo M, Pukkala E, Skytthe A & Hemminki K 2000 Environmental and heritable factors in the causation of cancer - analyses of cohorts of twins from Sweden, Denmark, and Finland. New England Journal of Medicine 343 78-85.
-
(2000)
New England Journal of Medicine
, vol.343
, pp. 78-85
-
-
Lichtenstein, P.1
Holm, N.V.2
Verkasalo, P.K.3
Iliadou, A.4
Kaprio, J.5
Koskenvuo, M.6
Pukkala, E.7
Skytthe, A.8
Hemminki, K.9
-
20
-
-
20344390516
-
Prostate cancer risk and IRS1, IRS2, IGFI, and INS polymorphisms: Strong association of IRS1 G972R variant and cancer risk
-
Neuhausen SL, Slattery ML, Garner CP, Ding YC, Hoffman M & Brothman AR 2005 Prostate cancer risk and IRS1, IRS2, IGFI, and INS polymorphisms: strong association of IRS1 G972R variant and cancer risk. Prostate 64 168-174.
-
(2005)
Prostate
, vol.64
, pp. 168-174
-
-
Neuhausen, S.L.1
Slattery, M.L.2
Garner, C.P.3
Ding, Y.C.4
Hoffman, M.5
Brothman, A.R.6
-
21
-
-
0034973569
-
Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
-
Ritchie MD, Hahn LW, Roodi N, Bailey LR, Dupont WD, Parl FF & Moore JH 2001 Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. American Journal of Human Genetics 69 138-147.
-
(2001)
American Journal of Human Genetics
, vol.69
, pp. 138-147
-
-
Ritchie, M.D.1
Hahn, L.W.2
Roodi, N.3
Bailey, L.R.4
Dupont, W.D.5
Parl, F.F.6
Moore, J.H.7
-
22
-
-
0037014743
-
Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer
-
Sandhu MS, Dunger DB & Giovannucci EL 2002 Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer. Journal of National Cancer Institute 94 972-980.
-
(2002)
Journal of National Cancer Institute
, vol.94
, pp. 972-980
-
-
Sandhu, M.S.1
Dunger, D.B.2
Giovannucci, E.L.3
-
23
-
-
0033532877
-
Increased blood glucose and insulin, body size, and incident colorectal cancer
-
Schoen RE, Tangen CM, Kuller LH, Burke GL, Cushman M, Tracy RP, Dobs A & Savage PJ 1999 Increased blood glucose and insulin, body size, and incident colorectal cancer. Journal of National Cancer Institute 91 1147-1154.
-
(1999)
Journal of National Cancer Institute
, vol.91
, pp. 1147-1154
-
-
Schoen, R.E.1
Tangen, C.M.2
Kuller, L.H.3
Burke, G.L.4
Cushman, M.5
Tracy, R.P.6
Dobs, A.7
Savage, P.J.8
-
24
-
-
3142770705
-
Associations among IRS1, IRS2, IGFI, and IGFBP3 genetic polymorphisms and colorectal cancer
-
Slattery ML, Samowitz W, Curtin K, Ma KN, Hoffman M, Caan B & Neuhausen S 2004 Associations among IRS1, IRS2, IGFI, and IGFBP3 genetic polymorphisms and colorectal cancer. Cancer Epidemiology, Biomarkers and Prevention 13 1206-1214.
-
(2004)
Cancer Epidemiology, Biomarkers and Prevention
, vol.13
, pp. 1206-1214
-
-
Slattery, M.L.1
Samowitz, W.2
Curtin, K.3
Ma, K.N.4
Hoffman, M.5
Caan, B.6
Neuhausen, S.7
-
25
-
-
33644680756
-
Polymorphisms in IGF-binding protein 1 are associated with impaired renal function in type 2 diabetes
-
Stephens RH, McElduff P, Heald AH, New JP, Worthington J, Ollier WE & Gibson JM 2005 Polymorphisms in IGF-binding protein 1 are associated with impaired renal function in type 2 diabetes. Diabetes 54 3547-3553.
-
(2005)
Diabetes
, vol.54
, pp. 3547-3553
-
-
Stephens, R.H.1
McElduff, P.2
Heald, A.H.3
New, J.P.4
Worthington, J.5
Ollier, W.E.6
Gibson, J.M.7
-
26
-
-
10344254808
-
The insulin-like growth factor-I pathway mediator genes: SHC1 Met300Val shows a protective effect in breast cancer
-
Wagner K, Hemminki K, Grzybowska E, Klaes R, Butkiewicz D, Pamula J, Pekala W, Zientek H, Mielzynska D, Siwinska E et al. 2004 The insulin-like growth factor-I pathway mediator genes: SHC1 Met300Val shows a protective effect in breast cancer. Carcinogenesis 25 2473-2478.
-
(2004)
Carcinogenesis
, vol.25
, pp. 2473-2478
-
-
Wagner, K.1
Hemminki, K.2
Grzybowska, E.3
Klaes, R.4
Butkiewicz, D.5
Pamula, J.6
Pekala, W.7
Zientek, H.8
Mielzynska, D.9
Siwinska, E.10
-
27
-
-
34547739530
-
The GH1/IGF-1 axis polymorphisms and their impact on breast cancer development
-
Wagner K, Hemminki K & Forsti A 2007 The GH1/IGF-1 axis polymorphisms and their impact on breast cancer development. Breast Cancer Research Treatment 104 233-248.
-
(2007)
Breast Cancer Research Treatment
, vol.104
, pp. 233-248
-
-
Wagner, K.1
Hemminki, K.2
Forsti, A.3
-
28
-
-
0034805447
-
Identification of a cis-acting element and a novel trans-acting factor of the human insulin receptor gene in HepG2 and rat liver cells
-
Yoshizato K, Shirotani T, Furukawa N, Taguchi T, Motoshima H, Toyonaga T, Hirashima Y, Kawashima J, Ebina Y, Shichiri M et al. 2001 Identification of a cis-acting element and a novel trans-acting factor of the human insulin receptor gene in HepG2 and rat liver cells. Biochemical and Biophysical Research Communications 280 428-434.
-
(2001)
Biochemical and Biophysical Research Communications
, vol.280
, pp. 428-434
-
-
Yoshizato, K.1
Shirotani, T.2
Furukawa, N.3
Taguchi, T.4
Motoshima, H.5
Toyonaga, T.6
Hirashima, Y.7
Kawashima, J.8
Ebina, Y.9
Shichiri, M.10
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