The role of hypoxia inducible factor-1α in the increased MMP-2 and MMP-9 production by human monocytes exposed to nickel nanoparticles

Nanotoxicology

Volumn 5, Issue 4, 2011, Pages 568-582

  Wan, Rong ^a   Mo, Yiqun ^a   Chien, Sufan ^b   Li, Yihua ^a   Li, Yixin ^a   Tollerud, David J ^a   Zhang, Qunwei ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Human monocyte U937; Hypoxia inducible factor 1 ; Matrix metalloproteinases; Metal nanoparticles; Tissue inhibitor of metalloproteinases

Indexed keywords

GELATINASE A; GELATINASE B; HEAT SHOCK PROTEIN 90 INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; METAL NANOPARTICLE; NICKEL; TANESPIMYCIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TITANIUM DIOXIDE;

ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SYNTHESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; NANOTECHNOLOGY; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANALYSIS OF VARIANCE; BENZOQUINONES; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KINETICS; LACTAMS, MACROCYCLIC; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METAL NANOPARTICLES; MONOCYTES; NICKEL; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TITANIUM; U937 CELLS;

RATTUS;

EID: 80655125256     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2010.537791     Document Type: Article

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