Matrix metalloproteinase-2 and -9 are induced differently by metal nanoparticles in human monocytes: The role of oxidative stress and protein tyrosine kinase activation

Toxicology and Applied Pharmacology

Volumn 233, Issue 2, 2008, Pages 276-285

  Wan, Rong ^a,d   Mo, Yiqun ^a   Zhang, Xing ^b   Chien, Sufan ^c   Tollerud, David J ^a   Zhang, Qunwei ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c University of Louisville School of Medicine   (United States)

^d FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Human monocyte cell line U937; Matrix metalloproteinases; Metal nanoparticles; Tissue inhibitors of metalloproteinases

Indexed keywords

CURCUMIN; CYTOKINE; GELATINASE A; GELATINASE B; GENISTEIN; HERBIMYCIN A; MESSENGER RNA; METAL NANOPARTICLE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TITANIUM DIOXIDE; TRANSCRIPTION FACTOR AP 1; TRANSITION ELEMENT;

ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; FOREIGN BODY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LEUKOCYTE; MONOCYTE; OXIDATIVE STRESS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

COBALT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME PRECURSORS; GELATINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MONOCYTES; NANOPARTICLES; OXIDATIVE STRESS; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS; TITANIUM; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; U937 CELLS;

EID: 56049124072     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.08.022     Document Type: Article

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