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Volumn 879, Issue 30, 2011, Pages 3465-3474
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Simultaneous quantification of nicotine and metabolites in rat brain by liquid chromatography-tandem mass spectrometry
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Author keywords
Brain; Liquid chromatography mass spectrometry; Metabolites; Nicotine; Rat
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Indexed keywords
ANALYTES;
ANALYTICAL METHOD;
BRAIN TISSUE;
CALIBRATION CURVES;
COTININE;
EXTRACTION RECOVERY;
GRADIENT ELUTION;
INTERNAL STANDARDS;
LC-MS/MS;
LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY;
LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY;
MATRIX EFFECTS;
MULTIPLE REACTION MONITORING;
NICOTINE;
OVERALL PROCESS EFFICIENCIES;
POSITIVE ELECTROSPRAY IONIZATION;
RAT BRAIN;
RAT BRAIN TISSUE;
SOLID-PHASE EXTRACTION;
TARGET ANALYTES;
VALIDATED METHODS;
BIOMOLECULES;
BRAIN;
COLUMN CHROMATOGRAPHY;
DEUTERIUM;
ELECTROSPRAY IONIZATION;
EXTRACTION;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
HISTOLOGY;
MASS SPECTROMETRY;
METABOLISM;
METABOLITES;
PYRIDINE;
QUALITY CONTROL;
RATS;
TISSUE;
LIQUIDS;
3' HYDROXYCOTININE;
ANABASINE;
ANATABINE;
COTININE;
COTININE N BETA DEXTRO GLUCURONIDE;
COTININE N OXIDE;
NICOTINE;
NICOTINE DERIVATIVE;
NICOTINE N BETA DEXTRO GLUCURONIDE;
NICOTINE N' OXIDE;
NORCOTININE;
NORNICOTINE;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ANIMAL TISSUE;
ARTICLE;
CALIBRATION;
CONCENTRATION (PARAMETERS);
ELECTROSPRAY MASS SPECTROMETRY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
LIQUID CHROMATOGRAPHY;
MALE;
MASS SPECTROMETRY;
NEUROTOXICITY;
NONHUMAN;
PRIORITY JOURNAL;
QUALITY CONTROL;
RAT;
SOLID PHASE EXTRACTION;
ALKALOIDS;
ANABASINE;
ANIMALS;
BIOLOGICAL MARKERS;
BRAIN CHEMISTRY;
CHROMATOGRAPHY, LIQUID;
COTININE;
LINEAR MODELS;
MALE;
NICOTINE;
PYRIDINES;
RATS;
RATS, SPRAGUE-DAWLEY;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
RATTUS;
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EID: 80555150610
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2011.09.026 Document Type: Article |
Times cited : (31)
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References (40)
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