-
1
-
-
0344845003
-
Epithelial-mesenchymal transitions in development and pathologies
-
Thiery, J. P. (2003) Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell. Biol. 15, 740-746
-
(2003)
Curr. Opin. Cell. Biol.
, vol.15
, pp. 740-746
-
-
Thiery, J.P.1
-
2
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri, R., and Weinberg, R. A. (2009) The basics of epithelial-mesenchymal transition. J. Clin. Invest. 119, 1420-1428
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
3
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
DOI 10.1038/nrm1835, PII NRM1835
-
Thiery, J. P., and Sleeman, J. P. (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7, 131-142 (Pubitemid 43278296)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.2
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
4
-
-
79953303497
-
A systems view of epithelial-mesenchymal transition signaling states
-
Thomson, S., Petti, F., Sujka-Kwok, I., Mercado, P., Bean, J., Monaghan, M., Seymour, S. L., Argast, G. M., Epstein, D. M., and Haley, J. D. (2011) A systems view of epithelial-mesenchymal transition signaling states. Clin. Exp. Metastasis 28, 137-155
-
(2011)
Clin. Exp. Metastasis
, vol.28
, pp. 137-155
-
-
Thomson, S.1
Petti, F.2
Sujka-Kwok, I.3
Mercado, P.4
Bean, J.5
Monaghan, M.6
Seymour, S.L.7
Argast, G.M.8
Epstein, D.M.9
Haley, J.D.10
-
5
-
-
34548175512
-
Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
-
DOI 10.1111/j.1349-7006.2007.00550.x
-
Moustakas, A., and Heldin, C. H. (2007) Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression. Cancer Sci. 98, 1512-1520 (Pubitemid 47308444)
-
(2007)
Cancer Science
, vol.98
, Issue.10
, pp. 1512-1520
-
-
Moustakas, A.1
Heldin, C.-H.2
-
6
-
-
59449090107
-
TGFβ-induced epithelial to mesenchymal transition
-
Xu, J., Lamouille, S., and Derynck, R. (2009) TGFβ-induced epithelial to mesenchymal transition. Cell Res. 19, 156-172
-
(2009)
Cell Res.
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
7
-
-
70450142560
-
Inflammation and EMT: An alliance towards organ fibrosis and cancer progression
-
López-Novoa, J. M., and Nieto, M. A. (2009) Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol. Med. 1, 303-314
-
(2009)
EMBO Mol. Med.
, vol.1
, pp. 303-314
-
-
López-Novoa, J.M.1
Nieto, M.A.2
-
8
-
-
77956178360
-
EMT, cancer stem cells, and drug resistance: An emerging axis of evil in the war on cancer
-
Singh, A., and Settleman, J. (2010) EMT, cancer stem cells, and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 29, 4741-4751
-
(2010)
Oncogene
, vol.29
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
9
-
-
0034778447
-
EGFR and cancer prognosis
-
Nicholson, R. J., Gee, J. M., and Harper, M. E. (2001) EGFR and cancer prognosis. Eur. J. Cancer 37, 9-15
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 9-15
-
-
Nicholson, R.J.1
Gee, J.M.2
Harper, M.E.3
-
10
-
-
33847718214
-
The EGF receptor family: spearheading a merger of signaling and therapeutics
-
DOI 10.1016/j.ceb.2007.02.008, PII S0955067407000221
-
Bublil, E. M., and Yarden, Y. (2007) The EGF receptor family: spearheading a merger of signaling and therapeutics. Curr. Opin. Cell. Biol. 19, 124-134 (Pubitemid 46386405)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.2
, pp. 124-134
-
-
Bublil, E.M.1
Yarden, Y.2
-
11
-
-
1842471336
-
Signaling through the epidermal growth factor receptor during the development of malignancy
-
DOI 10.1016/j.pharmthera.2004.01.002, PII S0163725804000208
-
Grandis, J. R., and Sok, J. C. (2004) Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol. Ther. 102, 37-46 (Pubitemid 38429984)
-
(2004)
Pharmacology and Therapeutics
, vol.102
, Issue.1
, pp. 37-46
-
-
Grandis, J.R.1
Sok, J.C.2
-
13
-
-
34250711876
-
Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma
-
DOI 10.1158/1535-7163.MCT-07-0138
-
Frederick, B. A., Helfrich, B. A., Coldren, C. D., Zheng, D., Chan, D., Bunn, P. A., Jr., and Raben, D. (2007) Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma. Mol. Cancer Ther. 6, 1683-1691 (Pubitemid 46954044)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.6
, pp. 1683-1691
-
-
Frederick, B.A.1
Helfrich, B.A.2
Coldren, C.D.3
Zheng, D.4
Chan, D.5
Bunn Jr., P.A.6
Raben, D.7
-
14
-
-
57049132745
-
Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy
-
Thomson, S., Petti, F., Sujka-Kwok, I., Epstein, D., and Haley, J. D. (2008) Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy. Clin. Exp. Metastasis 25, 843-854
-
(2008)
Clin. Exp. Metastasis
, vol.25
, pp. 843-854
-
-
Thomson, S.1
Petti, F.2
Sujka-Kwok, I.3
Epstein, D.4
Haley, J.D.5
-
15
-
-
47549092230
-
Bypassing cellular EGF receptor dependence through epithelial-to- mesenchymal-like transitions
-
Barr, S., Thomson, S., Buck, E., Russo, S., Petti, F., Sujka-Kwok, I., Eyzaguirre, A., Rosenfeld-Franklin, M., Gibson, N. W., Miglarese, M., Epstein, D., Iwata, K. K., and Haley, J. D. (2008) Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions. Clin. Exp. Metastasis 25, 685-693
-
(2008)
Clin. Exp. Metastasis
, vol.25
, pp. 685-693
-
-
Barr, S.1
Thomson, S.2
Buck, E.3
Russo, S.4
Petti, F.5
Sujka-Kwok, I.6
Eyzaguirre, A.7
Rosenfeld-Franklin, M.8
Gibson, N.W.9
Miglarese, M.10
Epstein, D.11
Iwata, K.K.12
Haley, J.D.13
-
16
-
-
0036141447
-
Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
-
Chakravarti, A., Loeffler, J. S., and Dyson, N. J. (2002) Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res. 62, 200-207 (Pubitemid 34074005)
-
(2002)
Cancer Research
, vol.62
, Issue.1
, pp. 200-207
-
-
Chakravarti, A.1
Loeffler, J.S.2
Dyson, N.J.3
-
17
-
-
0035177216
-
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
-
DOI 10.1101/gad.828901
-
Elenbaas, B., Spirio, L., Koerner, F., Fleming, M. D., Zimonjic, D. B., Donaher, J. L., Popescu, N. C., Hahn, W. C., and Weinberg, R. A. (2001) Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev. 15, 50-65 (Pubitemid 32060682)
-
(2001)
Genes and Development
, vol.15
, Issue.1
, pp. 50-65
-
-
Elenbaas, B.1
Spirio, L.2
Koerner, F.3
Fleming, M.D.4
Zimonjic, D.B.5
Donaher, J.L.6
Popescu, N.C.7
Hahn, W.C.8
Weinberg, R.A.9
-
18
-
-
77957262381
-
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
-
Taube, J. H., Herschkowitz, J. I., Komurov, K., Zhou, A. Y., Gupta, S., Yang, J., Hartwell, K., Onder, T. T., Gupta, P. B., Evans, K. W., Hollier, B. G., Ram, P. T., Lander, E. S., Rosen, J. M., Weinberg, R. A., and Mani, S. A. (2010) Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc. Natl. Acad. Sci. U.S.A. 107, 15449-15454
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 15449-15454
-
-
Taube, J.H.1
Herschkowitz, J.I.2
Komurov, K.3
Zhou, A.Y.4
Gupta, S.5
Yang, J.6
Hartwell, K.7
Onder, T.T.8
Gupta, P.B.9
Evans, K.W.10
Hollier, B.G.11
Ram, P.T.12
Lander, E.S.13
Rosen, J.M.14
Weinberg, R.A.15
Mani, S.A.16
-
19
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
DOI 10.1016/j.cell.2004.06.006, PII S0092867404005768
-
Yang, J., Mani, S. A., Donaher, J. L., Ramaswamy, S., Itzykson, R. A., Come, C., Savagner, P., Gitelman, I., Richardson, A., and Weinberg, R. A. (2004) Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117, 927-939 (Pubitemid 38798858)
-
(2004)
Cell
, vol.117
, Issue.7
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
20
-
-
21244437500
-
Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
-
DOI 10.1245/ASO.2005.04.010
-
Martin, T. A., Goyal, A., Watkins, G., and Jiang, W. G. (2005) Expression of the transcription factors Snail, Slug, and Twist and their clinical significance in human breast cancer. Ann. Surg. Oncol. 12, 488-496 (Pubitemid 40884264)
-
(2005)
Annals of Surgical Oncology
, vol.12
, Issue.6
, pp. 488-496
-
-
Martin, T.A.1
Goyal, A.2
Watkins, G.3
Jiang, W.G.4
-
21
-
-
79952499030
-
Twist1-induced invadopodia formation promotes tumor metastasis
-
Eckert, M. A., Lwin, T. M., Chang, A. T., Kim, J., Danis, E., Ohno-Machado, L., and Yang, J. (2011) Twist1-induced invadopodia formation promotes tumor metastasis. Cancer Cell 19, 372-386
-
(2011)
Cancer Cell
, vol.19
, pp. 372-386
-
-
Eckert, M.A.1
Lwin, T.M.2
Chang, A.T.3
Kim, J.4
Danis, E.5
Ohno-Machado, L.6
Yang, J.7
-
22
-
-
79951555293
-
Transcription factors Zeb1, Twist, and Snail in breast carcinoma
-
Soini, Y., Tuhkanen, H., Sironen, R., Virtanen, I., Kataja, V., Auvinen, P., Mannermaa, A., and Kosma, V. M. (2011) Transcription factors Zeb1, Twist, and Snail in breast carcinoma. BMC Cancer 11, 73
-
(2011)
BMC Cancer
, vol.11
, pp. 73
-
-
Soini, Y.1
Tuhkanen, H.2
Sironen, R.3
Virtanen, I.4
Kataja, V.5
Auvinen, P.6
Mannermaa, A.7
Kosma, V.M.8
-
23
-
-
69149108735
-
Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer
-
Ponzo, M. G., Lesurf, R., Petkiewicz, S., O'Malley, F. P., Pinnaduwage, D., Andrulis, I. L., Bull, S. B., Chughtai, N., Zuo, D., Souleimanova, M., Germain, D., Omeroglu, A., Cardiff, R. D., Hallett, M., and Park, M. (2009) Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer. Proc. Natl. Acad. Sci. U.S.A. 106, 12903-12908
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 12903-12908
-
-
Ponzo, M.G.1
Lesurf, R.2
Petkiewicz, S.3
O'Malley, F.P.4
Pinnaduwage, D.5
Andrulis, I.L.6
Bull, S.B.7
Chughtai, N.8
Zuo, D.9
Souleimanova, M.10
Germain, D.11
Omeroglu, A.12
Cardiff, R.D.13
Hallett, M.14
Park, M.15
-
24
-
-
67650831418
-
Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer
-
Ma, J., DeFrances, M. C., Zou, C., Johnson, C., Ferrell, R., and Zarnegar, R. (2009) Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer. J. Clin. Invest. 119, 478-491
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 478-491
-
-
Ma, J.1
DeFrances, M.C.2
Zou, C.3
Johnson, C.4
Ferrell, R.5
Zarnegar, R.6
-
25
-
-
36549089022
-
Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells
-
Hutcheson, I. R., Knowlden, J. M., Hiscox, S. E., Barrow, D., Gee, J. M., Robertson, J. F., Ellis, I. O., and Nicholson, R. I. (2007) Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells. Breast Cancer Res. 9, R50
-
(2007)
Breast Cancer Res.
, vol.9
-
-
Hutcheson, I.R.1
Knowlden, J.M.2
Hiscox, S.E.3
Barrow, D.4
Gee, J.M.5
Robertson, J.F.6
Ellis, I.O.7
Nicholson, R.I.8
-
26
-
-
57349179996
-
Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence
-
Kim, H. D., Guo, T. W., Wu, A. P., Wells, A., Gertler, F. B., and Lauffenburger, D. A. (2008) Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence. Mol. Biol. Cell 19, 4249-4259
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4249-4259
-
-
Kim, H.D.1
Guo, T.W.2
Wu, A.P.3
Wells, A.4
Gertler, F.B.5
Lauffenburger, D.A.6
-
27
-
-
4544381664
-
Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data
-
DOI 10.1089/cmb.2004.11.544
-
Janes, K. A., Kelly, J. R., Gaudet, S., Albeck, J. G., Sorger, P. K., and Lauffenburger, D. A. (2004) Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data. J. Comput. Biol. 11, 544-561 (Pubitemid 39238373)
-
(2004)
Journal of Computational Biology
, vol.11
, Issue.4
, pp. 544-561
-
-
Janes, K.A.1
Kelly, J.R.2
Gaudet, S.3
Albeck, J.G.4
Sorger, P.K.5
Lauffenburger, D.A.6
-
30
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini, Y., and Hochberg, Y. (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. Roy. Stat. Soc. B Met. 57, 289-300
-
(1995)
J. Roy. Stat. Soc. B Met.
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
31
-
-
0042424602
-
Statistical significance for genome-wide studies
-
Storey, J. D., and Tibshirani, R. (2003) Statistical significance for genome-wide studies. Proc. Natl. Acad. Sci. U.S.A. 100, 9440-9445
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
32
-
-
36249012382
-
EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation
-
DOI 10.1242/jcs.010488
-
Joslin, E. J., Opresko, L. K., Wells, A., Wiley, H. S., and Lauffenburger, D. A. (2007) EGF receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation. J. Cell Sci. 120, 3688-3699 (Pubitemid 350120960)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.20
, pp. 3688-3699
-
-
Joslin, E.J.1
Opresko, L.K.2
Wells, A.3
Wiley, H.S.4
Lauffenburger, D.A.5
-
33
-
-
78650512223
-
Collective cell migration requires suppression of actomysoin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
-
Hidalgo-Carcedo, C., Hooper, S., Chaudhry, S. I., Williamson, P., Harrington, K., Leitinger, B., and Sahai, E. (2011) Collective cell migration requires suppression of actomysoin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. Nat. Cell Biol. 13, 49-58
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 49-58
-
-
Hidalgo-Carcedo, C.1
Hooper, S.2
Chaudhry, S.I.3
Williamson, P.4
Harrington, K.5
Leitinger, B.6
Sahai, E.7
-
34
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
DOI 10.1016/j.ccr.2006.10.008, PII S153561080600314X
-
Neve, R. M., Chin, K., Fridlyand, J., Yeh, J., Baehner, F. L., Fevr, T., Clark, L., Bayani, N., Coppe, J. P., Tong, F., Speed, T., Spellman, P. T., DeVries, S., Lapuk, A., Wang, N. J., Kuo, W. L., Stilwell, J. L., Pinkel, D., Albertson, D. G., Waldman, F. M., McCormick, F., Dickson, R. B., Johnson, M. D., Lippman, M., Ethier, S., Gazdar, A., and Gray, J. W. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10, 515-527 (Pubitemid 44854747)
-
(2006)
Cancer Cell
, vol.10
, Issue.6
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
Clark, L.7
Bayani, N.8
Coppe, J.-P.9
Tong, F.10
Speed, T.11
Spellman, P.T.12
DeVries, S.13
Lapuk, A.14
Wang, N.J.15
Kuo, W.-L.16
Stilwell, J.L.17
Pinkel, D.18
Albertson, D.G.19
Waldman, F.M.20
McCormick, F.21
Dickson, R.B.22
Johnson, M.D.23
Lippman, M.24
Ethier, S.25
Gazdar, A.26
Gray, J.W.27
more..
-
35
-
-
47549102418
-
Epithelial-mesenchymal transition traits in human breast cancer cell lines
-
Blick, T., Widodo, E., Hugo, H., Waltham, M., Lenburg, M. E., Neve, R. M., and Thompson, E. W. (2008) Epithelial-mesenchymal transition traits in human breast cancer cell lines. Clin. Exp. Metastasis 25, 629-642
-
(2008)
Clin. Exp. Metastasis
, vol.25
, pp. 629-642
-
-
Blick, T.1
Widodo, E.2
Hugo, H.3
Waltham, M.4
Lenburg, M.E.5
Neve, R.M.6
Thompson, E.W.7
-
36
-
-
77954718424
-
Predictive biomarkers to tyrosine kinase inhibitors for the epidermal growth factor receptor in non-smallcell lung cancer
-
DeLuca, A., and Normanno, N. (2010) Predictive biomarkers to tyrosine kinase inhibitors for the epidermal growth factor receptor in non-smallcell lung cancer. Curr. Drug Targets 11, 851-864
-
(2010)
Curr. Drug Targets
, vol.11
, pp. 851-864
-
-
DeLuca, A.1
Normanno, N.2
-
37
-
-
33947576034
-
The importance of c-Kit and PDGF receptors as potential targets for molecular therapy in breast cancer
-
DOI 10.2174/092986707780090963
-
Roussidis, A. E., Theocharis, A. D., Tzanakakis, G. N., and Karamanos, N. K. (2007) The importance of c-Kit and PDGF receptors as potential targets for molecular therapy in breast cancer. Curr. Med. Chem. 14, 735-743 (Pubitemid 46477708)
-
(2007)
Current Medicinal Chemistry
, vol.14
, Issue.7
, pp. 735-743
-
-
Roussidis, A.E.1
Theocharis, A.D.2
Tzanakakis, G.N.3
Karamanos, N.K.4
-
38
-
-
2442426180
-
Epidermal Growth Factor Induces Fibroblast Contractility and Motility via a Protein Kinase C δ-dependent Pathway
-
DOI 10.1074/jbc.M311981200
-
Iwabu, A., Smith, K., Allen, F. D., Lauffenburger, D. A., and Wells, A. (2004) Epidermal growth factor induces fibroblast contractility and motility via a protein kinase Cδ-dependent pathway. J. Biol. Chem. 279, 14551-14560 (Pubitemid 38618842)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.15
, pp. 14551-14560
-
-
Iwabu, A.1
Smith, K.2
Allen, F.D.3
Lauffenburger, D.A.4
Wells, A.5
-
39
-
-
12344321571
-
Discovery of meaningful associations in genomic data using partial correlation coefficients
-
DOI 10.1093/bioinformatics/bth445
-
de la Fuente, A., Bing, N., Hoeschele, I., and Mendes, P. (2004) Discovery of meaningful associations in genomic data using partial correlation coefficients. Bioinformatics 20, 3565-3574 (Pubitemid 40136792)
-
(2004)
Bioinformatics
, vol.20
, Issue.18
, pp. 3565-3574
-
-
De La, F.A.1
Bing, N.2
Hoeschele, I.3
Mendes, P.4
-
40
-
-
77954726255
-
Emerging targeted therapies for breast cancer
-
Alvarez, R. H., Valero, V., and Hortobagyi, G. N. (2010) Emerging targeted therapies for breast cancer. J. Clin. Oncol. 28, 3366-3379
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3366-3379
-
-
Alvarez, R.H.1
Valero, V.2
Hortobagyi, G.N.3
-
41
-
-
45549088083
-
Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism
-
Havasi, A., Li, Z., Wang, Z., Martin, J. L., Botla, V., Ruchalski, K., Schwartz, J. H., and Borkan, S. C. (2008) Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. J. Biol. Chem. 283, 12305-12313
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 12305-12313
-
-
Havasi, A.1
Li, Z.2
Wang, Z.3
Martin, J.L.4
Botla, V.5
Ruchalski, K.6
Schwartz, J.H.7
Borkan, S.C.8
-
42
-
-
78649669332
-
Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of survival
-
Kanagasabai, R., Karthikeyan, K., Vedam, K., Qien, W., Zhu, Q., and Ilangovan, G. (2010) Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of survival. Mol. Cancer Res. 8, 1399-1412
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 1399-1412
-
-
Kanagasabai, R.1
Karthikeyan, K.2
Vedam, K.3
Qien, W.4
Zhu, Q.5
Ilangovan, G.6
-
43
-
-
77951966160
-
Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells
-
Ahmed, M., and Kundu, G. C. (2010) Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells. Mol. Cancer 9, 101
-
(2010)
Mol. Cancer
, vol.9
, pp. 101
-
-
Ahmed, M.1
Kundu, G.C.2
-
44
-
-
73549121061
-
Effects of combined inhibition of MEK and mTOR on downstream signaling and tumor growth in pancreatic cancer xenograft models
-
Chang, Q., Chen, E., and Hedley, D. W. (2009) Effects of combined inhibition of MEK and mTOR on downstream signaling and tumor growth in pancreatic cancer xenograft models. Cancer Biol. Ther. 8, 1893-1901
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 1893-1901
-
-
Chang, Q.1
Chen, E.2
Hedley, D.W.3
-
45
-
-
75749103348
-
Src signaling in cancer invasion
-
Guarino, M. (2010) Src signaling in cancer invasion. J. Cell. Physiol. 223, 14-26
-
(2010)
J. Cell. Physiol.
, vol.223
, pp. 14-26
-
-
Guarino, M.1
-
46
-
-
34447569172
-
Protein kinase Cepsilon may act as EGF-inducible scaffold protein for phospholipase Cgamma1
-
Valkova, C., Maerz, S., Imhof, D., and Liebmann, C. (2007) Protein kinase Cepsilon may act as EGF-inducible scaffold protein for phospholipase Cgamma1. Cell Signal. 19, 1830-1843
-
(2007)
Cell Signal.
, vol.19
, pp. 1830-1843
-
-
Valkova, C.1
Maerz, S.2
Imhof, D.3
Liebmann, C.4
-
47
-
-
56649100563
-
SRC-dependent signalling regulates actin ruffle formation induced by glycerophosphoinositol 4-phosphate
-
Filippi, B. M., Mariggiò, S., Pulvirenti, T., and Corda, D. (2008) SRC-dependent signalling regulates actin ruffle formation induced by glycerophosphoinositol 4-phosphate. Biochim. Biophys. Acta 1783, 2311-2322
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 2311-2322
-
-
Filippi, B.M.1
Mariggiò, S.2
Pulvirenti, T.3
Corda, D.4
-
48
-
-
18344390740
-
Suppression of cell migration by protein kinase Cδ
-
DOI 10.1038/sj.onc.1208465
-
Jackson, D., Zheng, Y., Lyo, D., Shen, Y., Nakayama, K., Nakayama, K. I., Humphries, M. J., Ryland, M. E., and Foster, D. A. (2005) Suppression of cell migration by protein kinase Cδ. Oncogene 24, 3067-3072 (Pubitemid 40675540)
-
(2005)
Oncogene
, vol.24
, Issue.18
, pp. 3067-3072
-
-
Jackson, D.1
Zheng, Y.2
Lyo, D.3
Shen, Y.4
Nakayama, K.5
Nakayama, K.I.6
Humphries, M.J.7
Reyland, M.E.8
Foster, D.A.9
-
49
-
-
0141542627
-
Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells
-
Kruger, J. S., and Reddy, K. B. (2003) Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells. Mol. Cancer Res. 1, 801-809 (Pubitemid 37174451)
-
(2003)
Molecular Cancer Research
, vol.1
, Issue.11
, pp. 801-809
-
-
Kruger, J.S.1
Reddy, K.B.2
-
50
-
-
60049091422
-
KITENIN recruits Dishevelled/PKCδ to form a functional complex and controls the migration and invasiveness of colorectal cancer cells
-
Kho, D. H., Bae, J. A., Lee, J. H., Cho, H. J., Cho, S. H., Lee, J. H., Seo, Y. W., Ahn, K. Y., Chung, I. J., and Kim, K. K. (2009) KITENIN recruits Dishevelled/PKCδ to form a functional complex and controls the migration and invasiveness of colorectal cancer cells. Gut 58, 509-519
-
(2009)
Gut
, vol.58
, pp. 509-519
-
-
Kho, D.H.1
Bae, J.A.2
Lee, J.H.3
Cho, H.J.4
Cho, S.H.5
Lee, J.H.6
Seo, Y.W.7
Ahn, K.Y.8
Chung, I.J.9
Kim, K.K.10
-
51
-
-
1542327692
-
Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentation signaling
-
DOI 10.1073/pnas.0308768101
-
Prudhomme, W., Daley, G. Q., Zandstra, P., and Lauffenburger, D. A. (2004) Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signaling. Proc. Natl. Acad. Sci. U.S.A. 101, 2900-2905 (Pubitemid 38327708)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.9
, pp. 2900-2905
-
-
Prudhomme, W.1
Daley, G.Q.2
Zandstra, P.3
Lauffenburger, D.A.4
-
52
-
-
28844441230
-
Cell signaling: A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
-
DOI 10.1126/science.1116598
-
Janes, K. A., Albeck, J. G., Gaudet, S., Sorger, P. K., Lauffenburger, D. A., and Yaffe, M. B. (2005) Systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science 310, 1646-1653 (Pubitemid 41780781)
-
(2005)
Science
, vol.310
, Issue.5754
, pp. 1646-1653
-
-
Janes, K.A.1
Albeck, J.G.2
Gaudet, S.3
Sorger, P.K.4
Lauffenburger, D.A.5
Yaffe, M.B.6
-
53
-
-
34247127891
-
Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response
-
Kemp, M. L., Wille, L., Lewis, C. L., Nicholson, L. B., and Lauffenburger, D. A. (2007) Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response. J. Immunol. 178, 4984-4992 (Pubitemid 46595281)
-
(2007)
Journal of Immunology
, vol.178
, Issue.8
, pp. 4984-4992
-
-
Kemp, M.L.1
Wille, L.2
Lewis, C.3
Nicholson, L.B.4
Lauffenburger, D.A.5
-
54
-
-
44249090908
-
Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells
-
DOI 10.1124/mol.107.043794
-
Kumar, N., Afeyan, R., Kim, H. D., and Lauffenburger, D. A. (2008) Multipathway model enables prediction of kinase inhibitor cross-talk on migration of HER2-overexpressing mammary epithelial cells. Mol. Pharmacol. 73, 1668-1678 (Pubitemid 351724356)
-
(2008)
Molecular Pharmacology
, vol.73
, Issue.6
, pp. 1668-1678
-
-
Kumar, N.1
Afeyan, R.2
Kim, H.-D.3
Lauffenburger, D.A.4
|