Glutathione peroxidases at work on epididymal spermatozoa: An example of the dual effect of reactive oxygen species on mammalian male fertilizing ability

Journal of Andrology

Volumn 32, Issue 6, 2011, Pages 641-650

  Noblanc, Anaís ^a   Kocer, Ayhan ^a   Chabory, Eléonore ^b   Vernet, Patrick ^a   Saez, Fabrice ^a   Cadet, Rémi ^a   Conrad, Marcus ^c,d   Drevet, Joël R ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b Laboratoire de Biologie de la Reproduction   (France)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Disulfide bridges; DNA condensation; DNA oxidation; Genomic stability; Hydrogen peroxide; Lipid peroxidation; Protamines

Indexed keywords

DNA; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE PEROXIDASE 3; GLUTATHIONE PEROXIDASE 5; MESSENGER RNA; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE; SELENIUM; UNCLASSIFIED DRUG;

CELL NUCLEUS; DNA DAMAGE; DNA FRAGMENTATION; ENZYME ACTIVITY; EPIDIDYMIS; FERTILIZATION; INTRACYTOPLASMIC SPERM INJECTION; LIPID PEROXIDATION; MALE FERTILITY; MALE INFERTILITY; MAMMAL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SPERMATOGENESIS; SPERMATOZOON; SPERMATOZOON MATURATION;

ANIMALS; EPIDIDYMIS; FERTILIZATION; GLUTATHIONE PEROXIDASE; HUMANS; MALE; MICE; RATS; REACTIVE OXYGEN SPECIES; SPERM MATURATION; SPERMATOZOA;

EID: 80455178791     PISSN: 01963635     EISSN: 19394640     Source Type: Journal    
DOI: 10.2164/jandrol.110.012823     Document Type: Review

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