Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Mirković, Bojana ^a   Sosič, Izidor ^a   Gobec, Stanislav ^a   Kos, Janko ^a,b  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPHENOL; 5 AMINOQUINOLINE 8 OL; AMINOQUINOLINE DERIVATIVE; CATALASE; CATHEPSIN; CATHEPSIN B; CATHEPSIN H; CATHEPSIN L; CYSTEINE PROTEINASE; DICHLORODIHYDROFLUORESCEIN DIACETATE; HYDROGEN PEROXIDE; HYDROXYL GROUP; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 4-AMINOPHENOL; AMINOPHENOL DERIVATIVE; CYSTEINE; FLUORESCENT DYE; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME KINETICS; FALSE POSITIVE RESULT; MASS SPECTROMETRY; OXIDATION REDUCTION REACTION; SIGNAL TRANSDUCTION; CHEMISTRY; DRUG ANTAGONISM; HUMAN; ISOELECTRIC FOCUSING; KINETICS; METABOLISM;

AMINOPHENOLS; CATHEPSIN B; CYSTEINE; FLUORESCENT DYES; HUMANS; ISOELECTRIC FOCUSING; KINETICS; MASS SPECTROMETRY; OXIDATION-REDUCTION; PROTEASE INHIBITORS; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS;

EID: 80455145191     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027197     Document Type: Article

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