메뉴 건너뛰기




Volumn 7, Issue 7, 2011, Pages 773-781

Beneficial effect of aqueous Stem Bark Extracts of Strychnos henningsii Gilg in Streptozotocin-nicotinamide induced type 2 diabetic wistar rats

Author keywords

Biochemical; Clinical significance; Diabetes mellitus; Hematological analysis; Nicotinamide; Streptozotocin; Strychnos henningsii

Indexed keywords

ALANINE AMINOTRANSFERASE; ALANINE PHOSPHATASE; ALBUMIN; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; CALCIUM; CHOLESTEROL; GLIBENCLAMIDE; GLOBULIN; GLUCOSE; HEMOGLOBIN; NICOTINAMIDE; PHOSPHATASE; PLANT EXTRACT; STREPTOZOCIN; STRYCHNOS HENNINGSII EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA; URIC ACID;

EID: 80455127190     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2011.773.781     Document Type: Article
Times cited : (13)

References (40)
  • 1
    • 34147165556 scopus 로고    scopus 로고
    • Effects of some plants of the spurge family on haematological and biochemical parameters in rats
    • Adedapo, A.A., M.O. Abatan and O.O. Olorunsogo, 2007. Effects of some plants of the spurge family on haematological and biochemical parameters in rats. Vet. Arhiv, 77: 29-38.
    • (2007) Vet. Arhiv , vol.77 , pp. 29-38
    • Adedapo, A.A.1    Abatan, M.O.2    Olorunsogo, O.O.3
  • 2
    • 34248386492 scopus 로고    scopus 로고
    • Modulatory effects of ginger and clove oils on physiological responses in streptozotocin-induced diabetic rats
    • Al-Attar, A.M. and T.A. Zari, 2007. Modulatory effects of ginger and clove oils on physiological responses in streptozotocin-induced diabetic rats. Int. J. Pharmacol., 3: 34-40.
    • (2007) Int. J. Pharmacol. , vol.3 , pp. 34-40
    • Al-Attar, A.M.1    Zari, T.A.2
  • 3
    • 10744225371 scopus 로고    scopus 로고
    • Antidiabetic activity of red wine polyphenolic extract, ethanol or both in streptozotocin-treated rats
    • Al-Awwadi, N., J. Azay, P. Poucheret, G. Cassanas and M. Krosniak et al., 2004. Antidiabetic activity of red wine polyphenolic extract, ethanol or both in streptozotocin-treated rats. J. Agric. Food Chem., 52: 1008-1016.
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 1008-1016
    • Al-Awwadi, N.1    Azay, J.2    Poucheret, P.3    Cassanas, G.4    Krosniak, M.5
  • 4
    • 79958058849 scopus 로고    scopus 로고
    • Distribution of ABO and RH blood group alleles in Mandi Bahauddin District of Punjab, Pakistan
    • Anees, M., A. Jawad and I. Hashmi, 2007. Distribution of ABO and RH blood group alleles in Mandi Bahauddin District of Punjab, Pakistan. Proc. Pak. Acad. Sci., 44: 289-294.
    • (2007) Proc. Pak. Acad. Sci. , vol.44 , pp. 289-294
    • Anees, M.1    Jawad, A.2    Hashmi, I.3
  • 5
    • 76549090791 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic activities of Trianthema portulacastrum Linn. plant in normal and alloxan induced diabetic rats
    • Anreddy, R.N.R., M. Porika, N.R. Yellu and R.K. Devarakonda, 2010. Hypoglycemic and hypolipidemic activities of Trianthema portulacastrum Linn. plant in normal and alloxan induced diabetic rats. Int. J. Pharmacol., 6: 129-133.
    • (2010) Int. J. Pharmacol. , vol.6 , pp. 129-133
    • Anreddy, R.N.R.1    Porika, M.2    Yellu, N.R.3    Devarakonda, R.K.4
  • 6
    • 0036267519 scopus 로고    scopus 로고
    • Improvement of insulin sensitivity by perindopril in spontaneously hypertensive and streptozotocin-diabetic rats
    • Arun, G.S. and K.G. Ramesh, 2002. Improvement of insulin sensitivity by perindopril in spontaneously hypertensive and streptozotocin-diabetic rats. Indian J. Pharmacol., 34: 156-164.
    • (2002) Indian J. Pharmacol. , vol.34 , pp. 156-164
    • Arun, G.S.1    Ramesh, K.G.2
  • 7
    • 34548660456 scopus 로고    scopus 로고
    • Effect of Vernonia amygdalina Del leaf on kidney function of diabetic rats
    • Atangwho, I.J., P.E. Ebong, M.U. Eteng, E.U. Eyong and A.U. Obi, 2007. Effect of Vernonia amygdalina Del leaf on kidney function of diabetic rats. Int. J. Pharmacol., 3: 143-148.
    • (2007) Int. J. Pharmacol. , vol.3 , pp. 143-148
    • Atangwho, I.J.1    Ebong, P.E.2    Eteng, M.U.3    Eyong, E.U.4    Obi, A.U.5
  • 8
    • 0027417614 scopus 로고    scopus 로고
    • Diabetic nephropathy. What you need to know to preserve kidney function?
    • Bakris, G.L., 1997. Diabetic nephropathy. What you need to know to preserve kidney function? Postgrad. Med., 93: 89-100.
    • (1997) Postgrad. Med. , vol.93 , pp. 89-100
    • Bakris, G.L.1
  • 9
    • 42649126720 scopus 로고    scopus 로고
    • Antidiabetic activity of aqueous root extract of Ichnocarpus frutescens in streptozotocin-nicotinamide induced type-II diabetes in rats
    • Barik, R., S. Jain, D. Qwatra, A. Joshi, G.S. Tripathi and R. Goyal, 2008. Antidiabetic activity of aqueous root extract of Ichnocarpus frutescens in streptozotocin-nicotinamide induced type-II diabetes in rats. Indian J. Pharmacol., 40: 19-22.
    • (2008) Indian J. Pharmacol. , vol.40 , pp. 19-22
    • Barik, R.1    Jain, S.2    Qwatra, D.3    Joshi, A.4    Tripathi, G.S.5    Goyal, R.6
  • 10
    • 33747618478 scopus 로고    scopus 로고
    • Antihyperglycemic activity of aqueous root extract of Rubia cordifolia in streptozotocin-induced diabetic rats
    • Baskar, R., L.M. Bhakshu, G.V. Bharathi, S.S. Reddy, R. Karuna, G.K. Reddy and D. Saralakumari, 2006. Antihyperglycemic activity of aqueous root extract of Rubia cordifolia in streptozotocin-induced diabetic rats. Pharm. Biol., 44: 475-479.
    • (2006) Pharm. Biol. , vol.44 , pp. 475-479
    • Baskar, R.1    Bhakshu, L.M.2    Bharathi, G.V.3    Reddy, S.S.4    Karuna, R.5    Reddy, G.K.6    Saralakumari, D.7
  • 11
    • 0030832566 scopus 로고    scopus 로고
    • Antidiabetic and antihyperlipidemic effects of neem seed kernel powder on alloxan-diabetic rabbits
    • Bopanna, K.N., J. Kannan, S. Godgil, R. Balaraman and S.P. Rathod, 1997. Antidiabetic and antihyperlipidemic effects of neem seed kernel powder on alloxan-diabetic rabbits. Indian J. Pharmacol., 29: 162-172.
    • (1997) Indian J. Pharmacol. , vol.29 , pp. 162-172
    • Bopanna, K.N.1    Kannan, J.2    Godgil, S.3    Balaraman, R.4    Rathod, S.P.5
  • 12
    • 0028871133 scopus 로고
    • Excessive glucose production rather than insulin resistance accounts for hypoglycaemia in recent-onset diabetic rats
    • Burcelain, R., M. Eddouks, J. Maury, J. Kande, R. Assan and J. Girard, 1995. Excessive glucose production rather than insulin resistance accounts for hypoglycaemia in recent-onset diabetic rats. Diabetolgia, 38: 283-290.
    • (1995) Diabetolgia , vol.38 , pp. 283-290
    • Burcelain, R.1    Eddouks, M.2    Maury, J.3    Kande, J.4    Assan, R.5    Girard, J.6
  • 13
    • 1842454891 scopus 로고    scopus 로고
    • Conditions associated with very low values of glycohaemoglobin measured by an HPLC method
    • Camargo, J.L. and J.L. Gross, 2004. Conditions associated with very low values of glycohaemoglobin measured by an HPLC method. J. Clin Pathol., 57: 346-349.
    • (2004) J. Clin Pathol. , vol.57 , pp. 346-349
    • Camargo, J.L.1    Gross, J.L.2
  • 14
    • 47249084343 scopus 로고    scopus 로고
    • Advances in understanding pathogenic mechanisms of thrombophilic disorders
    • Dahlback, B., 2008. Advances in understanding pathogenic mechanisms of thrombophilic disorders. Blood, 112: 19-27.
    • (2008) Blood , vol.112 , pp. 19-27
    • Dahlback, B.1
  • 15
    • 0033990368 scopus 로고    scopus 로고
    • Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed wistar rats
    • Ghasi, S., E. Nwobodo and J.O. Ofili, 2000. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed wistar rats. J. Ethnopharm., 69: 21-25.
    • (2000) J. Ethnopharm. , vol.69 , pp. 21-25
    • Ghasi, S.1    Nwobodo, E.2    Ofili, J.O.3
  • 16
    • 0033712738 scopus 로고    scopus 로고
    • Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism
    • Grover, J.K., V. Vats and S.S. Rathi, 2000. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J. Ethnopharmacol., 73: 461-470.
    • (2000) J. Ethnopharmacol. , vol.73 , pp. 461-470
    • Grover, J.K.1    Vats, V.2    Rathi, S.S.3
  • 17
    • 77953965826 scopus 로고    scopus 로고
    • The effects of methanol extract derived from Urtica pilulifera leaves on some hematological and biochemical parameters of diabetic rats
    • Irshaid, F. and K. Mansi, 2009. The effects of methanol extract derived from Urtica pilulifera leaves on some hematological and biochemical parameters of diabetic rats. Res. J. Biol. Sci., 4: 675-681.
    • (2009) Res. J. Biol. Sci. , vol.4 , pp. 675-681
    • Irshaid, F.1    Mansi, K.2
  • 18
    • 33846256215 scopus 로고    scopus 로고
    • Hepatoprotective and antioxidant activities of Vernonia amygdalina on acetaminophen-induced hepatic damage in mice
    • Iwalokun, B.A., B.U. Efedede, J.A. Alabi-Sofunde, T. Oduala, O.A. Magbagbeola and A.I. Akinwande, 2006. Hepatoprotective and antioxidant activities of Vernonia amygdalina on acetaminophen-induced hepatic damage in mice. J. Med. Food, 9: 524-530.
    • (2006) J. Med. Food , vol.9 , pp. 524-530
    • Iwalokun, B.A.1    Efedede, B.U.2    Alabi-Sofunde, J.A.3    Oduala, T.4    Magbagbeola, O.A.5    Akinwande, A.I.6
  • 19
    • 0014606996 scopus 로고
    • Diabetogenic action of streptozotocin: Relationship of dose to metabolic response
    • Junod, A., A.E. Lambert, W. Stauffacher and A.E. Renold, 1969. Diabetogenic action of streptozotocin: Relationship of dose to metabolic response. J. Clin. Invest., 48: 2129-2139.
    • (1969) J. Clin. Invest. , vol.48 , pp. 2129-2139
    • Junod, A.1    Lambert, A.E.2    Stauffacher, W.3    Renold, A.E.4
  • 20
    • 79959437718 scopus 로고    scopus 로고
    • Pharmacology and phytochemistry of Pakistani herbs and herbal drugs used for treatment of diabetes
    • Karim, A., M. Nouman, S. Munir and S. Sattar, 2011. Pharmacology and phytochemistry of Pakistani herbs and herbal drugs used for treatment of diabetes. Int. J. Pharmacol., 7: 419-439.
    • (2011) Int. J. Pharmacol. , vol.7 , pp. 419-439
    • Karim, A.1    Nouman, M.2    Munir, S.3    Sattar, S.4
  • 21
    • 0024240517 scopus 로고
    • Mechanisms of nicotinamide and thymidine protection from alloxan and streptozotocin toxicity
    • LeDoux, S.P., C.R. Hall, P.M. Forbes, N.J. Patton and G.L. Wilson, 1988. Mechanisms of nicotinamide and thymidine protection from alloxan and streptozotocin toxicity. Diabetes, 37: 1015-1019.
    • (1988) Diabetes , vol.37 , pp. 1015-1019
    • LeDoux, S.P.1    Hall, C.R.2    Forbes, P.M.3    Patton, N.J.4    Wilson, G.L.5
  • 22
    • 79957871538 scopus 로고    scopus 로고
    • Anti-diabetic effects of aqueous ethanolic extract of Hibiscus rosasinensis L. on streptozotocin-induced diabetic rats and the possible morphologic changes in the liver and kidney
    • Mandade, R. and S.A. Sreenivas, 2011. Anti-diabetic effects of aqueous ethanolic extract of Hibiscus rosasinensis L. on streptozotocin-induced diabetic rats and the possible morphologic changes in the liver and kidney. Int. J. Pharmacol., 7: 363-369.
    • (2011) Int. J. Pharmacol. , vol.7 , pp. 363-369
    • Mandade, R.1    Sreenivas, S.A.2
  • 23
    • 0031939587 scopus 로고    scopus 로고
    • Experimental NIDDM: Development of a new model in adult rats administered streptozotocin and nicotinamide
    • Masiello, P., C. Broca, R. Gross, M. Roye and M. Manteghetti et al., 1998. Experimental NIDDM: Development of a new model in adult rats administered streptozotocin and nicotinamide. Diabetes, 47: 224-229.
    • (1998) Diabetes , vol.47 , pp. 224-229
    • Masiello, P.1    Broca, C.2    Gross, R.3    Roye, M.4    Manteghetti, M.5
  • 24
    • 33744918517 scopus 로고    scopus 로고
    • Establishment and pathophysiological characterization of type 2 diabetic mouse model produced by streptozotocin and nicotinamide
    • Nakamura, T., T. Terajima, T. Ogata, K. Ueno, N. Hashimoto, K. Ono and S. Yano, 2006. Establishment and pathophysiological characterization of type 2 diabetic mouse model produced by streptozotocin and nicotinamide. Biol. Pharm. Bull., 29: 1167-1174.
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 1167-1174
    • Nakamura, T.1    Terajima, T.2    Ogata, T.3    Ueno, K.4    Hashimoto, N.5    Ono, K.6    Yano, S.7
  • 25
    • 43949098249 scopus 로고    scopus 로고
    • Antidiabetic activity of Aloe vera and histology of organs in streptozotocin-induced diabetic rats
    • Noor, A., S. Gunasekaran, A.S. Manickam and M.A. Vijayalakshmi, 2008. Antidiabetic activity of Aloe vera and histology of organs in streptozotocin-induced diabetic rats. Curr. Sci., 94: 1070-1076.
    • (2008) Curr. Sci. , vol.94 , pp. 1070-1076
    • Noor, A.1    Gunasekaran, S.2    Manickam, A.S.3    Vijayalakshmi, M.A.4
  • 26
    • 0037454716 scopus 로고    scopus 로고
    • Augmented lipopolysaccharide-induction of the histamine-forming enzyme in streptozotocin-induced diabetic mice
    • Oguri, S., K. Motegi and Y. Endo, 2003. Augmented lipopolysaccharide-induction of the histamine-forming enzyme in streptozotocin-induced diabetic mice. Biochem. Biophys. Acta, 1637: 83-90.
    • (2003) Biochem. Biophys. Acta , vol.1637 , pp. 83-90
    • Oguri, S.1    Motegi, K.2    Endo, Y.3
  • 27
    • 75649151676 scopus 로고    scopus 로고
    • Ethnobotanical survey of medicinal plants used for the management of diabetes mellitus in the Nkonkobe municipality of South Africa
    • Oyedemi, S.O., G. Bradley and A.J. Afolayan, 2009. Ethnobotanical survey of medicinal plants used for the management of diabetes mellitus in the Nkonkobe municipality of South Africa. J. Med. Plants Res., 3: 1040-1044.
    • (2009) J. Med. Plants Res. , vol.3 , pp. 1040-1044
    • Oyedemi, S.O.1    Bradley, G.2    Afolayan, A.J.3
  • 28
    • 77953681402 scopus 로고    scopus 로고
    • In vitro and in vivo antioxidant activities of aqueous extract of Strychnos henningsii Gilg
    • Oyedemi, S.O., G. Bradley and A.J. Afolayan, 2010a. In vitro and in vivo antioxidant activities of aqueous extract of Strychnos henningsii Gilg. Afr. J. Pharm. Pharmacol., 4: 70-78.
    • (2010) Afr. J. Pharm. Pharmacol. , vol.4 , pp. 70-78
    • Oyedemi, S.O.1    Bradley, G.2    Afolayan, A.J.3
  • 29
    • 80455161635 scopus 로고    scopus 로고
    • Toxicological effects of the aqueous stem bark extract of Strychnos henningsii Gilg in Wistar rats
    • Oyedemi, S.O., G. Bradley and A.J. Afolayan, 2010b. Toxicological effects of the aqueous stem bark extract of Strychnos henningsii Gilg in Wistar rats. J. Nat. Pharm., 1: 33-39.
    • (2010) J. Nat. Pharm. , vol.1 , pp. 33-39
    • Oyedemi, S.O.1    Bradley, G.2    Afolayan, A.J.3
  • 30
    • 79959423975 scopus 로고    scopus 로고
    • Antidiabetic and haematological effect of aqueous stem bark extract of Afzelia Africana (Smith) on streptozotocin-induced diabetic Wistar rats
    • Oyedemi, S.O., E.A. Adewusi, O.A. Aiyegoro and D.A. Akinpelu, 2011. Antidiabetic and haematological effect of aqueous stem bark extract of Afzelia Africana (Smith) on streptozotocin-induced diabetic Wistar rats. Asian Pac. J. Trop. Biomed., 1: 353-358.
    • (2011) Asian Pac. J. Trop. Biomed. , vol.1 , pp. 353-358
    • Oyedemi, S.O.1    Adewusi, E.A.2    Aiyegoro, O.A.3    Akinpelu, D.A.4
  • 31
    • 84925351689 scopus 로고    scopus 로고
    • Paul, A.J., 2002. Streptozotocin. http://www. answers.com/topic/streptozotocin#ixzzl KvPBTumc
    • (2002) Streptozotocin
    • Paul, A.J.1
  • 32
    • 60249089485 scopus 로고    scopus 로고
    • Protective role of Tephrosia purpurea ethanolic seed extract on glycoprotein components in streptozotocin induced diabetic rats
    • Pavana, P., S. Sethupathy and S. Manoharan, 2008. Protective role of Tephrosia purpurea ethanolic seed extract on glycoprotein components in streptozotocin induced diabetic rats. Int. J. Pharmacol., 4: 114-119.
    • (2008) Int. J. Pharmacol. , vol.4 , pp. 114-119
    • Pavana, P.1    Sethupathy, S.2    Manoharan, S.3
  • 34
    • 0035073812 scopus 로고    scopus 로고
    • Hypoglycemic and antihyperglycemic activity of Syzygium alternifolium (Wt.) Walp. seed extracts in normal and diabetic rats
    • Rao, B.K. and C.H. Rao, 2001. Hypoglycemic and antihyperglycemic activity of Syzygium alternifolium (Wt.) Walp. seed extracts in normal and diabetic rats. Phytomedicine, 8: 88-93.
    • (2001) Phytomedicine , vol.8 , pp. 88-93
    • Rao, B.K.1    Rao, C.H.2
  • 35
    • 34548657526 scopus 로고    scopus 로고
    • Effect of Equisetum arvense L. (Equisetaceae) in microalbuminuria and creatinine excretion in streptozotocin-induced diabetes in male rats
    • Safiyeh, S., F. Fathallah, N. Vahid, S.S. Habib and N. Nabat, 2007. Effect of Equisetum arvense L. (Equisetaceae) in microalbuminuria and creatinine excretion in streptozotocin-induced diabetes in male rats. Int. J. Pharmacol., 3: 155-159.
    • (2007) Int. J. Pharmacol. , vol.3 , pp. 155-159
    • Safiyeh, S.1    Fathallah, F.2    Vahid, N.3    Habib, S.S.4    Nabat, N.5
  • 36
    • 0025073589 scopus 로고
    • Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice
    • Swanston-Flatt, S.K., C. Day, C.J. Bailey and P.R. Flatt, 1990. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia, 33: 462-464.
    • (1990) Diabetologia , vol.33 , pp. 462-464
    • Swanston-Flatt, S.K.1    Day, C.2    Bailey, C.J.3    Flatt, P.R.4
  • 38
    • 0030896144 scopus 로고    scopus 로고
    • Serum magnesium and protein concentration during the 1st five years of insulin dependent diabetes in children
    • Tuvemo, T., U. Evald, M. Kobbah and L.A. Proos, 1997. Serum magnesium and protein concentration during the 1st five years of insulin dependent diabetes in children. Acta Paediatr. Suppl., 418: 7-10.
    • (1997) Acta Paediatr. Suppl. , vol.418 , pp. 7-10
    • Tuvemo, T.1    Evald, U.2    Kobbah, M.3    Proos, L.A.4
  • 39
    • 77953570914 scopus 로고    scopus 로고
    • Silymarin and milk thistle extract may prevent the progression of diabetic nephropathy in streptozotocin-induced diabetic rats
    • Vessal, G., M. Akmali, P. Najafi, M.R. Moein and M.M. Sagheb, 2010. Silymarin and milk thistle extract may prevent the progression of diabetic nephropathy in streptozotocin-induced diabetic rats. Renal Failure, 32: 733-739.
    • (2010) Renal Failure , vol.32 , pp. 733-739
    • Vessal, G.1    Akmali, M.2    Najafi, P.3    Moein, M.R.4    Sagheb, M.M.5
  • 40
    • 29244440389 scopus 로고    scopus 로고
    • Aphrodisiac potentials of aqueous extract of Fadogia agrestis (Schweinf. Ex Heim) stem in male albino rats
    • Yakubu, M.T., M.A. Akanji and A.T. Oladiji, 2005. Aphrodisiac potentials of aqueous extract of Fadogia agrestis (Schweinf. Ex Heim) stem in male albino rats. Asian J. Androl., 7: 399-404.
    • (2005) Asian J. Androl. , vol.7 , pp. 399-404
    • Yakubu, M.T.1    Akanji, M.A.2    Oladiji, A.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.